Helsinki University Central Hospital starts clinical trial of Preoperative i.v. Iron Substitution in Patients With Colon Cancer
Photo by Hans Reniers
The Helsinki University Central Hospital is enrolling patients into the clinical trial investigating Preoperative i.v. Iron Substitution in Patients With Colon Cancer (PREFECO).
About 70% of colon cancer patients are anemic. Preoperative anemia in patients with colorectal cancer is associated with both impaired disease-free survival and overall survival. The purpose of this study is to compare the effects of preoperative iv iron substitution on postoperative recovery in preoperatively anemic (male Hb <130, female Hb <120) and iron deficient colon cancer patients in a prospective setup. As a primary outcome, the effect of iv-iron substitution on postoperative complications is investigated.
The trial is designed to enrol male and female 18 Years to 100 years and is being conducted in the Jorvi Hospital, Espoo, HUS, Finland.
The study start date is October 1, 2020.
Among the criteria that allow participation, the following are indicated:
- Age> 18 years
- Dg: Colon ca
- The planned measure: the colon resection
- Men: Hb <130, women: Hb <120 and iron deficiency (elevated TfR, low TrFesat or low ferritin)
Patients with the following pathologies:
- hyperreactivity for Ferinject
- haemochromatosis
are excluded from participation.
This page provides a more detailed overview of this clinical trial: https://ichgcp.net/clinical-trials-registry/NCT04653181
