Research Association conducts clinical trial of Eye Movements Recording Using a Smartphone

Photo by Bacila Vlad

Bibliographic Research Association for Neurosciences (Association de Recherche Bibliographique pour les Neurosciences) is enrolling patients into the clinical trial investigating Eye Movements Recording Using a Smartphone: Comparison to Standard Video-oculography in Patients With Multiple Sclerosis.

This study aims to compare measurements obtained through the e-VOG application (mobile application, usable on mobile phones or tablets, to measure eye movements) with measurements from the standard video-oculography device (Eye-Tracker®T2), in patient with Multiple Sclerosis.
Based on literature, investigators hypothesize that it would be relevant to focus more broadly on subclinical abnormalities of oculomotricity in multiple sclerosis (MS). However, the difficulty of accessing video-oculography platforms (or eye-tracking devices) is probably one of the main limitations to performing this type of assessment.

To respond this problem, the "Resources and Skills Center-Multiple Sclerosis" (CRC SEP) team at the Nice University Hospital Center (France) has developed a mobile application (named e-VOG), usable on mobile phones or tablets, to measure eye movements. e-VOG reproduces the classic paradigms of video-oculography to collect data similar to standard video-oculography recording (saccade latency and speed, anti-saccade error rate, presence of fixation abnormalities).

e-VOG will not replace standard video-oculography platforms, because its technical characteristics are not as high. But investigators hypothesize that this application could constitute a screening tool for subclinical oculomotor abnormalities, usable by neurologists in consultation, directly on their mobile, which would make it possible to select a smaller population of patients in whom a further exploration by standard video-oculography would be indicated.

Memory Center of the Rainier III Gerontologic Center (Princess Grace Hospital - Monaco) is equipped with a standard video-oculography device, also named eye-tracking device (Eye-Tracker®T2), which records eye movements at a high frequency and measures saccades parameters (latency, speed, amplitudes etc).

This study is a collaborative study between the Center Rainier III team and the CRC SEP team in Nice. Its objective will be to compare measurements obtained through the e-VOG application with measurements from the standard video-oculography device.

The trial is designed to enroll male and female 18 years and older and is being conducted in the Centre Mémoire / Centre de Gérontologie Clinique Rainier III / Princess Grace Hospital, Monaco, Monaco.

The study start date is October 8, 2020.

The location of the study is entre Mémoire / Centre de Gérontologie Clinique Rainier III / Princess Grace Hospital, Monaco.

Participants will be recruited from patients with MS for whom a standard video-oculography exam is prescribed by the CRC SEP of the CHU de Nice (France) as part of routine care.

The patients that can be enrolled into this study include:

  • male or female
  • 18 years old and above
  • referred by a neurologist to perform a video-oculography (Eye-Tracking) examination as part of routine care
  • with Multiple Sclerosis (defined according to McDonald's 2017 criteria)
  • covered by a health insurance system

This page provides a more detailed overview of this clinical trial: https://ichgcp.net/clinical-trials-registry/NCT04702763

Clinical Research News

Upcoming Clinical Trials