Swiss University Hospital developes of a Keratoconus Detection Algorithm by Deep Learning Analysis and Its Validation on Eyestar Images

Photo by Liam Welch

University Hospital Inselspital, Berne is starting a new clinical trial of Development of a Keratoconus Detection Algorithm by Deep Learning Analysis and Its Validation on Eyestar Images.

This is a monocentric clinical study to develop an imaging analysis algorithm for the Eyestar 900 to identify keratoconus corneas and improve biometry for intraocular lens calculations.

Keratoconus is a progressive corneal ectatic disorder, characterised by thinning, protrusion and irregularity. Corneal imaging is crucial in keratoconus detection and progression analysis. Detection of keratoconus in early stages is important and has therapeutic consequence, whether to plan a surgical intervention or calculating an intraocular lens, before cataract surgery, as standard lens calculation techniques may lead to wrong results in patients with a keratoconus.

The Eyestar 900 is a swept-source OCT biometer and has the potential to be used for early keratoconus identification and progression analysis.

The clinical trial starts in February 15, 2021 and will continue throughout December 1, 2023.

Patients with all stages of keratoconus and healthy corneas can be enrolled into this study.

The indicators for exclusion are:

  • Keratoconus patients with hydrops, status following hydrops
  • Patients with degenerative corneal diseases
  • Patients after corneal surgery

The contacts and locations are the Universitätsklinik für Augenheilkunde, Inselspital, Bern, Switzerland.

The Inselspital, also named the University Hospital of Bern (Universitätsspital Bern), located in Bern, is one of the five university hospitals of Switzerland. It is associated with the University of Bern.

As of 2016, the hospital employs a staff of 7,255 and provides care for 250,000 patients each year. It also provides practical training to 600 medical students and over 1,000 other healthcare professionals.

The prominent physicians who have practiced in the Inselspital include Emil Theodor Kocher, the 1909 Nobel laureate.

For more details: https://ichgcp.net/clinical-trials-registry/NCT04763785

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