The largest hospital in Southern Denmark prodides Onco-Geriatric Screening of Cancer Patients Age 70 or More
Photo by Eberhard Grossgasteiger
The Odense University Hospital in collaboration with Academy of Geriatric Cancer Research, Danish Cancer Society and University of Southern Denmarkis commencing recruitment for the clinical trial of Onco-Geriatric Screening of Cancer Patients Age 70 or More (PROGNOSIS-G8).
Older patients with cancer constitute a heterogeneous group with varying comorbidity; therefore, geriatric assessment with initial screening is recommended. The Geriatric 8 (G8) has been established as a promising screening tool. Currently, there are no guidelines for oncogeriatric screening in older cancer patients in Denmark. The researchers hypothesize that by screening persons age 70 years or more with newly diagnosed cancer, with the G8, we can assess the prognostic value and identify a subgroup of patients who will benefit from a CGA.
The aims of the study are:
- Determine whether Danish cancer patients, with a G8 score of ≤14, experience poorer quality of life (QoL), receive less recommended standard cancer treatment, experience more treatment-related toxicity, stop treatment earlier, and experience shorter survival than patients with a G8 score >14.
- Ascertain whether the standard G8 cut-off score of ≤14 is the most relevant cut-off score, with respect to treatment adherence, treatment-related toxicity, QoL, and survival, when focusing on the older Danish cancer patient population.
- Establish whether the performance and prognostic value of the G8 can be strengthened through the addition of a functional measure, the 30-second chair stand test (30-CST), and/ or the handgrip strength test (HGST).
- Evaluate the prognostic value of the modified Geriatric 8 (mG8).
The trial is designed to enroll male and female 70 years and older and is being conducted in the Odense University Hospital, Odense, Fyn, Denmark.
All outpatients, age 70 years or more with solid malignancies, referred to the Department of Oncology at Odense University Hospital for antineoplastic treatment or information can be enrolled into this study.
This page provides a more detailed overview of this clinical trial: https://ichgcp.net/clinical-trials-registry/NCT04644874
