The study of association between olfactory training and quality of life following COVID-19

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Department of Otorhinolaryngology, Head and Neck Surgery & Audiology, Copenhagen University Hospital is commencing recruitment for the clinical trial of the Association Between Smell Training and Quality of Life in Patients With Impaired Sense of Smell Following COVID-19.

The trial officially began on June 29, 2022 and is planned to complete by September 30, 2025.

The impaired quality of life in patients with impaired sense of smell following COVID-19 can be possibly improved performing olfactory training with essential oils, compared to patients performing olfactory training with placebo oils. Patients will be given a diary to record their olfactory training.

The nurse or medical student instructing the patients in the training and performing the smell and taste tests is blinded.

Study population includes adult patients with impaired sense of taste and smell following COVID-19 > 3 months, experiencing hyposmia (15-30) or anosmia (<15) assessed by Sniffin' Sticks Olfactory Test for Threshold, Discrimination and Identification (TDI) performed in the Unit for Sense of Taste and Smell or medical assessment of parosmia based on medical history.  Patients with hyposmia, anosmia or parosmia of any origin other than COVID-19, or those who do not read or speak Danish, or who lack of compliance to perform daily olfactory training will be excluded from participation.

The link to the complete study profile:

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