Toxicology - Scientific & Management - Technical/Scientific

Toxicology - Scientific & Management - Technical/Scientific Req ID #:  79614 Location: 

Shrewsbury, MA, US, 01545 For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about. Job Summary The incumbent will serve as a lead Molecular Biology Scientist in the conduct of preclinical and clinical research studies at all levels of complexity. Responsibilities include study management, interpretation, and reporting of study data and assuring the regulatory compliance of these projects, as appropriate. Additional responsibilities include serving as a subject matter expert for the development and validation of molecular biology assays (eg: PCR, qPCR, ddPCR, genotyping and mRNA expression), as well as serving as the primary scientific contact for key clients and the on-site support of their programs.

ESSENTIAL DUTIES AND RESPONSIBILITIES:

• Function independently as a Study Director in the direction and execution of assigned studies in compliance with regulations as they apply to the conduct of preclinical and clinical research. Provide scientific expertise in study conduct, design, and interpretation.

• Participate in the proposal management and bid development process, serving as a key scientific contact

for new business generated from established business relationships.

• Participate in and coordinate all phases of the study planning process with appropriate departments.

• Design preclinical assays, generate high-quality laboratory method, protocols, amendments, reports, and develop appropriate changes to study design for assigned projects and programs.

• Review, interpret, integrate, and present data on assigned studies.

• Function independently as the point of contact for the planning and execution of sponsor interaction related to assigned studies, including proposal management and study scheduling, conduct and reporting.

• Function as a subject matter expert in molecular assays (qPCR and ddPCR) and provide oversight of the laboratory. Mentor technical staff in areas such as protocol interpretation, method development and refinement, study-related problem resolution, and technique validation.

• Provide technical and scientific guidance to the research staff.

• Attend scientific meetings, conferences, and training courses to enhance job and professional skills. Present abstracts/posters at national meetings, when appropriate, to maintain a scientific presence and visibility in areas of individual expertise.

• May supervise research and/or scientific staff, as appropriate for scope of responsibilities.

• May direct activities of assigned group(s) to ensure effective performance of function.

• Interview and select qualified exempt-level departmental personnel. Recommend, review, and approve personnel actions, including hiring, promotions and raises. Partner with Human Resources in the handling of disciplinary issues. Prepare and/or approve appropriate personnel action paperwork.

• Monitor performance of direct reports. Provide regular coaching and counseling. Prepare and deliver

salary and performance reviews; review and approve performance and salary appraisals initiated by direct reports.

• Ensure optimum performance of group function. Recommend and implement techniques to improve productivity, increase efficiencies, cut costs, take advantage e of opportunities, and maintain state -of-the-art practices.

• Perform testing facility management duties for the site as delegated by senior management.

• Perform all other related duties as assigned.

About Safety Assessment

Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market.  Each year approximately 300 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.

About Charles River

Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 17,000 employees within 90 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2019, revenue increased to $2.62 billion.

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2019.

Equal Employment Opportunity 

Charles River Laboratories is an Equal Opportunity Employer - M/F/Disabled/Vet

<span style="font-family:"Arial",sans-serif">If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to  <span style="font-family:"Arial",sans-serif">crrecruitment_US@crl.com <span style="font-family:"Arial",sans-serif">. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications <span style="font-family:"Arial",sans-serif">.

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Nearest Major Market: Worcester

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