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Associate Research Scientist-Image Analysis 1

Charles River Laboratories International Inc (CRL)

Durham, NC, US, 27703

Associate Research Scientist-Image Analysis 1 Req ID #:  135272 Location: 

Durham, NC, US, 27703 For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about. Job Summary Serve as a scientist in the conduct of assigned nonclinical research studies of basic complexity, to include study management, interpretation and reporting of study data, and assuring the regulatory compliance of these projects. The projects would mainly consist of quantitative specialty pathology projects, including histomorphometry (both manual and automated) and stereology.

We are seeking an Associate Research Scientist - Image Analysis for our Safety Assessment site located in Durham, NC.   .

The following are responsibilities related to the Associate Research Scientist:  With guidance from senior scientific staff, serve as a principal investigator in the direction and execution of assigned studies in compliance with GLP regulations as they apply to the conduct of nonclinical research.Generate high-quality study phase plans (if applicable) and reports appropriate for assigned studies. Utilize image analysis and stereology software, including method development, creation of algorithms, manual measurements, and data generation for morphometry and stereology studies. Conduct manual histomorphometric analysis under the light microscope, including enumeration of ovarian follicles and cell counts for labeling index determination. Review, interpret, integrate, and present data on assigned studies, using the assistance of senior scientific staff as appropriate.  This may include basic mathematical and statistical calculations and intermediate level stereology calculations as experience allows, as well as creation of data tables for reports. Function as contact, with guidance from senior scientific staff, for the planning and execution of sponsor interaction related to assigned studies, including proposal management and study scheduling, conduct and reporting.  Participate in study-related meetings and teleconferences. Provide guidance to the laboratory staff on the conduct of assigned studies. Assist senior scientific staff in the development of novel histology and pathology techniques. Attend scientific meetings, conferences and training courses to enhance job and professional skills. Review documentation of functions performed as part of quality control requirements.

The following are minimum qualifications related to the Associate Research Scientist position: Education: Bachelor's degree (B.S./B.A.) or equivalent in a scientific related discipline. Related Master's degree (M.S./M.A.) or PhD/DVM preferred. Experience:  Minimum of 5 years related experience in the contract research or pharmaceutical industry, to include at least 2 years as a Research Associate or equivalent role. An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above. Advanced knowledge of normal histology and the ability to recognize morphological changes in tissues. Ability to operate a light microscope. Previous experience in histomorphometry is highly desired.

  Experience in a histology lab, particularly with advanced techniques such as immunohistochemistry, is preferred but not required. Other:  Effective written and verbal communication skills. Ability to handle multiple projects, prioritize work and meet deadlines. Proficiency in the use of standard software including Microsoft® Excel, Word, PowerPoint, etc. and with standard laboratory calculations.  Experience using image analysis software is preferred but not required.


About Safety Assessment

Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market.  Each year approximately 120 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.


About Charles River

Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.


With over 14,000 employees within 80 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2018, revenue increased by 22% to $2.27 billion from $1.86 billion in 2017.

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2018.


Charles River Laboratories is an Equal Opportunity Employer - M/F/Disabled/Vet. If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to [email protected] This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.

Nearest Major Market: Durham

Nearest Secondary Market: Raleigh

Job Segment: Scientific, Toxicology, Biotech, Research Associate, Research Scientist, Science, Engineering, Research

2021-10-21 00:00:00

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