Research Scientist 1, Protein Engineering

Research Scientist 1, Protein Engineering Req ID #:  199931 Location: 

South San Francisco, CA, US, 94080 For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about. Job Summary  

We are seeking a Research Scientist for our Antibody Discovery site located in South San Francisco, CA.  

The successful candidate will work as a part of the Protein Sciences team to support purification and analytical characterization of recombinant proteins and antibodies. This role will require work primarily in a laboratory setting. You will possess strong analytical capability, interpersonal skills, a highly collaborative work ethic, the ability to adapt to changing needs, and the capacity to multitask to meet key goals.  

Key technical skills: 

•    Experience in different protein characterization technologies (DLS, HPLC, SEC-MALS, CE-SDS, Western Blot, ELISA, etc) is essential.

•    Knowledge and experience on antibody developability and protein formulation would be highly valued.

•    Recombinant protein purification experience using Ni-NTA, SEC, IEX, ProA columns is a plus.

•    Understanding and hands on experience with BLI is a plus. Job Qualifications  

The following are minimum requirements related to the Research Scientist position.

•    Education: Bachelor’s or Masters in Protein Chemistry, Biochemistry, Biology, or related fields.

•    Experience: Minimum of 2 years of laboratory experience in biotech/industry in a similar role.  

•    Basic understanding of protein and antibody purification and analytical characterization of recombinant proteins and antibodies strongly preferred. 

•    Highly motivated with a strong willingness to learn and grow. Must be able to work productively in a fast-paced, collaborative team environment.

•    Strong analytical and organizational skills are essential.

About RightSource (Biologics Testing)

The biopharmaceutical industry is growing at an unprecedented pace which is simultaneously changing current testing methodologies. To keep up with the demand, we offer a flexible testing platform which can be deployed on-site at the client site to their exact needs. Our biologics testing lab...in a box…at the client site. RightSource℠ is completely managed and operated using our quality management system, SOP’s, methods, and best practices. It’s as if you shipped your samples to an outsourced lab but walked down the hall instead.

Our Biologics Testing Solutions offers a variety of services such as contamination and impurity testing, protein characterization, bioassays, viral clearance studies and stability and lot release programs, we support clients throughout the biologic development cycle, from the establishment and characterization of cell banks through preclinical and clinical studies to marketed products. Whether clients need stand-alone services, a unique package of testing, or insourced support, our Biologics group can create a custom solution to suit their needs.  With more than 50 years of experience and proven regulatory expertise, the Charles River Biologics group can address challenging projects for biotechnology and pharmaceutical companies worldwide. Each year more than 20,000 biologic testing reports are sent each and over 200 licenses products are supported by our biologics testing solutions team. 

About Charles River

Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 20,000 employees within 110 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. 

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 86% of the drugs approved by the FDA in 2021.

At Charles River Laboratories, we recognize and recruit all talent. We are a company committed to the principle of diversity and inclusion and work daily in this direction.

For more information, please visit www.criver.com.

Nearest Major Market: San Francisco

Nearest Secondary Market: Oakland

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