Clinical trial investigating OCT Guided vs COmplete Pci- in patients with infarction
The company Azienda Ospedaliera Città della Salute e della Scienza di Torino is enrolling patients into the clinical trial investigating OCT Guided vs COmplete Pci in patieNts With sT Segment Elevation myocArdial infarCtion and mulTivessel Disease (OCT-CONTACT).
STEMI patients with multivessel disease will be randomized to complete PCI versus PCI driven by high risk criteria of plaques evaluated with OCT.
The principle by which OCT works is similar to ultrasound, although light waves close to infrared are used instead of ultrasounds. In practice, the light waves, emitted into the vessel through a special catheter positioned in the coronary artery, meet the surrounding structures and are partly absorbed and partly reflected by them. The reflected waves are picked up by a sensor positioned on the catheter and analyzed through software that produces images visible live on a special console.
The trial is designed to enroll male and female 18 Years and older and is being conducted in the Città della Salute e della Scienza di Torino, Torino, Piemonte, Italy; Ospedale San Luigi Gonzaga, Orbassano, Orbassano, Italy; Ospedale di Rivoli, Rivoli, Italy; AOU Città della Salute e della Scienza di Torino, Torino, Italy; Ospedale San Giovanni Bosco, Torino, Italy; Citta della Salute, Turin, Italy.
The study start date is February 1, 2021.
Inclusion Criteria: 1. Patients with STEMI and residual non culprit CAD 2. Informed consent.
Exclusion Criteria: 1. Refusal or inability to provide informed consent. 2. < 18 years of age 3. Cardiogenic shock 4. Previous Coronary Artery Bypass Grafting (CABG 5. Indication for revascularization by CABG. 6. eGFR < 30 ml/min/m2 7. ULM stenosis 8. Estimated life expectancy < 3 year 9. Non culprit CTO lesion
This page provides a more detailed overview of this clinical trial: https://ichgcp.net/clinical-trials-registry/NCT04878133
