Principal Scientist - Lab Sciences Bioanalytical

Principal Scientist - Lab Sciences Bioanalytical Req ID #:  73555 Location: 

Mattawan, MI, US, 49071 For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about. Job Summary We are seeking aPrincipal Scientistfor ourBioanalyticalTeamlocated inMattawan, MI.

ThePrincipal Scientist isresponsible for the development or oversight of the development of methods to quantify chemical entities, including small molecules, proteins, peptides, oligonucleotides and novel compounds using LC-MS/MS. This individual demonstrates expertise in the use of instrumentation and laboratory techniques and has the aptitude to drive implementation of new platforms including automation platforms. A Principal Scientist effectively applies his/her experience and knowledge to provide guidance for method development activities and troubleshooting method performance, providing scientific expertise to laboratory staff. This position may also be responsible for the general oversight and management of staff assigned to multiple departments or functions. A Principal Scientist is also responsible for developing and ensuring compliance to departmental policies and procedures. This individual is expected to be an expert in his/her discipline, providing leadership in developing staff and efficient and scientifically valid processes and procedures. This individual may function as a Principal Investigator or Study Director, responsible for the development and execution of validation and sample analysis protocols/plans in accordance with company standard operating procedures (SOPs), industry regulatory guidelines (GxP), and budgetary guidelines.

The following are the minimum requirements related to thePrincipal Scientistposition.

PhD in relevant field and 15-20 years of relevant experience (preferred); or Master's/Bachelor's degree in relevant field and 15-20 years of relevant experience (preferred). Proficient using laboratory software applications and LIMS. Expert knowledge of GxPs and industry guidance documents. Ability to work extended hours beyond normal work schedule to include, but not limited to, evenings,weekends, extended shifts and/or extra shifts, sometimes on short notice. Familiarity with Microsoft Office Suite. Ability to work under specific time constraints.

About Safety Assessment

Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market.  Each year approximately 120 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.

About Charles River

Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 17,000 employees within 90 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2019, revenue increased to $2.62 billion.

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2019.

Equal Employment Opportunity 

Charles River Laboratories is an Equal Opportunity Employer - M/F/Disabled/Vet

.

Nearest Major Market: Kalamazoo

Job Segment: Chemistry, Scientific, Toxicology, Laboratory, Biotech, Science, Engineering