The clinical study of microneedling for burn hypertrophic scars

The company Centre hospitalier de l'Université de Montréal (CHUM) is commencing recruitment for the clinical trial of the Microneedling for Burn Hypertrophic Scars.

The trial officially began on the January 22, 2021 and is planned to complete on June 20, 2026.

Approximately 33 to 91% of severe burn victims will develop hypertrophic scars. Hypertrophic scars are defined as erythematous (red), raised and rigid scars that can cause pain and itching, among other things. They cause psychological distress and affect the quality of life of burn victims. Microneedling is a technique that uses an electrical device to create hundreds of microchannels that penetrate the skin layers.

This study is interested in determining the effectiveness of microneedling in improving the pliability, thickness and erythema of hypertrophic scars. Each scar will receive up to 5 ACS-pen treatments followed by the application of cortisone (triamcinolone acetonide). Knowing that microneedling increases the absorption of products applied to the skin by about 80%, it is logical to think that creating these channels to the dermis and applying cortisone afterwards would have a beneficial effect on the hypertrophic scars of these patients.

The link to the complete study profile: https://ichgcp.net/clinical-trials-registry/NCT05423613 or https://clinicaltrials.gov/ct2/show/NCT05423613.