Acute Kidney Injury in Major Abdominal Surgery: Retrospective Study of 501 Patients
研究概览
地位
条件
详细说明
Ethical approval was submitted and approved by the regional ethical committee, Etisk prövningsnämnd Uppsala, # 2017/418.
Patients were selected from the time span of april 2016 to september 2017. The investigators identified 499 patients that had undergone any of the selected procedures. The procedures were, pancreatic resection, HIPEC surgery in colorectal setting, gynecological debulking in metastasized ovarian cancer, and liver resection.
The risk of acute kidney injury (AKI) by the KDIGO definition during the postoperative period will be estimated in the group as a whole, and for each type of surgery separately. In addition the data will be stratified by sex to investigate systematic gender disparities or physiological differences. Length of stay, thirty day and sixty day mortality will secondary endpoints.
研究类型
注册 (实际的)
参与标准
资格标准
适合学习的年龄
- 孩子
- 成人
- 年长者
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
Any of the selected procedures.
Exclusion Criteria:
Patient has expressed his or her will to nor participate in any study.
学习计划
研究是如何设计的？
设计细节
队列和干预
团体/队列 |
|---|
|
肝切除术
|
|
Pancreatic resection
|
|
HIPEC surgery
|
|
Gynecological debulking surgery
|
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Incidence of AKI
大体时间：the first 24- 72 hours postop
|
Frequency of AKI as defined by KDIGO
|
the first 24- 72 hours postop
|
次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Mortality
大体时间：30, 60 and 360 days postoperatively
|
30, 60, and 360 day mortality rate
|
30, 60 and 360 days postoperatively
|
|
Major Adverse Kidney Events
大体时间：30, 60 and 360 days postoperatively
|
Renal composite outcome according to Major Adverse Kidney Events (MAKE)
|
30, 60 and 360 days postoperatively
|
|
Fluid balance
大体时间：24-72h
|
Fluid balance during surgery, and the first postoperative days.
|
24-72h
|
|
Electrolyte disturbances
大体时间：24-72h
|
Any electrolyte disturbance.
|
24-72h
|
合作者和调查者
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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