Technical Specialist - Molecular

Medpace Holdings, Inc.

Singapore, Singapore

Job Summary

TheTechnical Specialist – Molecular at Medpace Reference Laboratories plays a pivotal role in research-based drug development within the pharmaceutical industry. Due to our recent growth, we are in need of qualified and focused driven individuals, like yourself. You would have the unique opportunity to work on the laboratory side of the fast-paced medical world by conducting tests on blood, tissue and other samples. If you have an analytical mind set, and enjoy working in a laboratory setting, this could be the opportunity for you!

The current opening is for a candidate with strong background in qPCR techniques for quantification of viruses as well as gene expression in different sample types using sample-to-result qPCR platforms, Sanger sequencing and Next Generation Sequencing using Illumina Platforms. The incumbent is also expected to have a broader knowledge of other molecular techniques especially cell culturing and genomics.

Responsibilities

  • Perform routine instrument maintenance and troubleshooting;
  • Expected to develop knowledge of federal regulations regarding clinical trials;
  • Expected to develop knowledge of pre-analytical variables affecting clinical laboratory testing;
  • Expected to develop knowledge of disease processes and correlation with clinical laboratory data;
  • Perform laboratory investigations;
  • Perform testing, documentation, and routine lab system operations;
  • Ensure validity of laboratory data reported.
  • Develop methods for routine and biomarker testing (primarily usingqPCR, Sanger sequencing and NGS) in our expanding laboratory.
  • Perform viral load and sequencing assays according to SOPs.
  • Participate in validation activities and participate in daily operation of the qPCR and sequencing platforms.
  • Participate in experimental design and instrument set-up.
  • Contribute to maintaining a Quality environment and participate actively in SOP writing; and
  • Maintain overview of inventory and orders.

Qualifications

  • Min. Master’s degree of Science.
  • Experience with qPCR techniques especially on large platforms such as the Abbott m2000 and the Roche Cobas;experience in Sanger and NGS sequencing
  • Experience in optimizing, and analyzing results.
  • Knowledge of principles of viral load, viral shedding and gene expression by qPCR, Sanger sequencing and NGS preferably in a central lab environment.
  • Knowledge of the Analyse-it data analysis statistical package is preferable;
  • Basic knowledge of drug therapy techniques and medical terminology;
  • Excellent written and verbal communication skills and good command of both written and spoken of English;
  • Able to work in a team environment with effective interpersonal skills and able to work independently; and

Job posted: 2023-03-08

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