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Influence of Ambient Temperature on Food Intake Through a Randomized Control Trial in an Office Setting

2015年3月11日 更新者:University of Alabama at Birmingham
Based on preliminary data and previous studies, the investigators hypothesize that the ambient temperature experienced by an individual influences his or her food intake in males and females aged 19 to 30. Specifically, exposure to temperatures above the thermoneutral zone (TNZ) will decrease consumption in young adults in a sedentary situation. Researchers will execute a randomized control trial specifically testing thermal exposure and its effect on an individual's food consumption. Participants will receive and wear a t-shirt. They will have a thermal image taken of the inner canthus of their eye and middle finger nail bed, representing a baseline of core and peripheral temperatures, respectively. They will be randomized to either a colder environment (65°F) or a warmer environment (75°F) under the artifice of monitoring routine office work with abnormal temperature conditions. Their knowledge of the experiment will be limited until the end. They will experience this temperature while filling out paperwork and performing basic office tasks. After one hour, another thermal image will be taken. Each participant will be presented with a large, Mellow Mushroom cheese pizza and directed to eat at their leisure and subsequently finish the office tasks over the next hour. The participants will then be debriefed on the parameters of the experiment and body measurements will be taken at the end so as to prevent bias of the subject by limiting their food intake. The investigators will quantify energy intake by weighing remaining food and comparing to known caloric content by weight from bomb calorimetry tests. The infrared thermal images will determine whether the temperatures experienced were extreme enough to initiate a change in thermoregulation.

調査の概要

詳細な説明

Previous studies suggest increased time spent outdoors is associated with lower body mass index (BMI).1,2 . In addition, energy expenditure and hunger have been associated with exposure to heat or cold. Increased usage of central heating and air conditioning systems coupled with increased time spent indoors has created an environment where humans are expending less energy to regulate their body temperature.3 The human thermoneutral zone (TNZ) is the range of ambient temperatures in which a healthy adult can maintain body temperature without expending energy beyond the normal basal metabolic rate. Energy intake and expenditure are adjusted at temperatures above and below the TNZ.4 The temperature of the food, smell, time of consumption, and number of people present are established factors that influence food consumption in humans.5 In addition, evidence supports the role of the environment upon an individual's food intake. Wall color, lighting, and ambient noise, influence consumption preferences and quantities.6 Based on research in animal models, particularly mice and livestock,food intake and subsequently, weight gain is reduced in high ambient temperatures.7-10 In addition in young, physically active, healthy males, food intake is inversely proportional to TNZ.11 However, energy expenditure increases above and below the TNZ. These studies are based on extreme conditions, therefore there is a lack of information on how small changes in ambient temperature may affect food intake in the general human public. Recent research shows the effectiveness of small changes over time to lead to changes in consumption practices.12 Thus, altering the thermal environment subtly may lead to a greater understanding of long term effects in weight management. The investigators have previously examined the thermal environment of persons going about their daily lives in both urban and rural settings (X120217008). Preliminary analysis of the results suggest increased % body fat is associated with lower heat exposure.

研究の種類

介入

入学 (実際)

20

段階

  • 適用できない

連絡先と場所

このセクションには、調査を実施する担当者の連絡先の詳細と、この調査が実施されている場所に関する情報が記載されています。

研究場所

    • Alabama
      • Birmingham、Alabama、アメリカ、35294-0022
        • University of Alabama at Birmingham School of Public Health

参加基準

研究者は、適格基準と呼ばれる特定の説明に適合する人を探します。これらの基準のいくつかの例は、人の一般的な健康状態または以前の治療です。

適格基準

就学可能な年齢

19年~35年 (大人)

健康ボランティアの受け入れ

いいえ

受講資格のある性別

全て

説明

Inclusion Criteria:

  • Inclusion Criteria:

    • Ages 19-35
    • Men and women

Exclusion Criteria:

  • Exclusion Criteria:

    • Any food allergy, including, but not limited to lactose or gluten intolerance.
    • Religious affiliations that include specific food guidelines.
    • Personal dietary restrictions, including but not limited to veganism.
    • Participation in any weight-reduction program, weight-loss diet, or other special diet within the previous 3 months.
    • Weight loss or gain of >5% of body weight in the past 6 months for any reason except post-partum weight loss.
    • Currently taking medication that suppresses or stimulates appetite or that affects body weight, including oral anti-diabetic medications.
    • History of prior surgical procedure for weight control or liposuction.
    • Anyone currently taking statins.
    • Self report of high blood pressure (above 140 systolic, 90 diastolic)
    • Current smoker or quit smoking less than 6 months prior.
    • Any major disease, including:
    • Active cancer or cancer requiring treatment in the past 2 years (except nonmelanoma skin cancer).

      • Active or chronic infections, including self-reported HIV positivity and active tuberculosis.
      • Active cardiovascular disease or event including hospitalization or therapeutic procedures for treatment of heart disease (e.g., coronary artery bypass, percutaneous transluminal coronary angioplasty) in the past 6 months; New York Heart Association Functional Class >2 with respect to congestive heart failure; stroke or transient ischemic attack in the past 6 months.
      • Gastrointestinal disease, including self-reported chronic hepatitis or cirrhosis, any episode of alcoholic hepatitis or alcoholic pancreatitis within past year, inflammatory bowel disease requiring treatment in the past year, recent or significant abdominal surgery (e.g., gastrectomy).
      • Active renal disease.
      • Lung disease: chronic obstructive airway disease requiring use of oxygen.
      • Diagnosed diabetes (type 1 or 2).
      • Uncompensated or uncontrolled psychiatric disease (such as schizophrenia and bipolar disorder) that, in opinion of the investigators, would impede conduct of the trial or completion of procedures.
    • Self reported history of or current eating disorders
    • Conditions or behaviors likely to effect the conduct of the trial: unable or unwilling to give informed consent; unable to communicate with the pertinent staff; another household member is a participant or staff member in the trial; current or anticipated participation in another research project that would interfere with the offered session; unwilling to accept condition assignment by randomization
    • Currently taking antidepressant, steroid, or thyroid medication, unless dosage has been stable for at least 6 months.
    • Self-report of a recent or ongoing problem with drug abuse or addiction.
    • Self report of excessive alcohol intake, either acute or chronic, defined as any one of the following: 1) average consumption of 3 or more alcohol containing beverages daily; 2) consumption of 7 or more alcoholic beverages within a 24-hr period in the past 12 months
    • Pregnancy and childbearing: currently pregnant or less than 3 months post partum; currently nursing or within 6 weeks of having completed nursing; pregnancy anticipated during between time of screening and session date; unwilling to report possible or confirmed pregnancies promptly during the course of the trial;
    • Students in the Environmental Health Science Department, Nutrition Sciences School, Any student, trainee, or post-doctoral fellow who is directly or indirectly receiving funding from the Nutrition Obesity Research Center.
    • Any other conditions which, in opinion of the investigators, would adversely affect the conduct of the trial.

研究計画

このセクションでは、研究がどのように設計され、研究が何を測定しているかなど、研究計画の詳細を提供します。

研究はどのように設計されていますか?

デザインの詳細

  • 主な目的:ヘルスサービス研究
  • 割り当て:ランダム化
  • 介入モデル:並列代入
  • マスキング:独身

武器と介入

参加者グループ / アーム
介入・治療
実験的:Cold
The cold treatment was 18-20°C (64.5-68°F), which is at the lower end of the thermalneutral zone in healthy adults.
実験的:Warm
The warm treatment was 25-27°C (77-80.6°F), which is above the range of the thermalneutral zone.

この研究は何を測定していますか?

主要な結果の測定

結果測定
メジャーの説明
時間枠
Food intake (kcalories)
時間枠:1 hour
Participants experienced the thermal environment for 1 hour and then were presented food (pizza) and had 1 hour to eat to their fill.
1 hour

二次結果の測定

結果測定
メジャーの説明
時間枠
Estimate of thermoregulation
時間枠:2 hours
An infrared thermal camera took thermal images of partipants inner canthus and 3rd fingernail bed as estimates of core and peripheral temperature respectively. The difference between core minus peripheral temperature estimates whether heat dissipation has been initiated.
2 hours

協力者と研究者

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出版物と役立つリンク

研究に関する情報を入力する責任者は、自発的にこれらの出版物を提供します。これらは、研究に関連するあらゆるものに関するものである可能性があります。

研究記録日

これらの日付は、ClinicalTrials.gov への研究記録と要約結果の提出の進捗状況を追跡します。研究記録と報告された結果は、国立医学図書館 (NLM) によって審査され、公開 Web サイトに掲載される前に、特定の品質管理基準を満たしていることが確認されます。

主要日程の研究

研究開始

2014年3月1日

一次修了 (実際)

2014年5月1日

研究の完了 (実際)

2014年5月1日

試験登録日

最初に提出

2015年3月6日

QC基準を満たした最初の提出物

2015年3月11日

最初の投稿 (見積もり)

2015年3月12日

学習記録の更新

投稿された最後の更新 (見積もり)

2015年3月12日

QC基準を満たした最後の更新が送信されました

2015年3月11日

最終確認日

2015年3月1日

詳しくは

本研究に関する用語

その他の研究ID番号

  • X140206006

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米国FDA規制医薬品の研究

いいえ

米国FDA規制機器製品の研究

いいえ

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いいえ

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