Relationship Between Biological Profiles and Clinical Evolutions Within the Same Cluster COVID-19 (COVIDCOLLECT) (COVIDCOLLECT)
2020年10月21日 更新者：University Hospital, Clermont-Ferrand
Biological Collection for the Study of the Relationship Between the Biological Profiles Observed and the Clinical Evolutions Within the Same Cluster of Transmission of the Coronavirus SARS-CoV-2
The hypothesis is that from a cluster defined by a confirmed positive case of COVID-19 and its contact cases, it is possible to study the different expressions and clinical evolutions of COVID-19 infection and to explore the biological profiles related to the observed clinical history. Certain biological determinants (virological, immunological, microbological or gentic) could indeed be correlated with the clinical presentation and/or be useful for personalized care.
The main objective is to study the relationship between the biological profiles observed and the clinical evolutions within the same cluster of transmission of the coronavirus SARS-CoV-2 (positive COVID-19 cases and contact subjects).
調査の概要
状態
わからない
詳細な説明
Subjects with a COVID-19 infection and thei contact cases (identification according to health insurance criteria, see "Améli.fr") will be offered a clinical evaluation and the takin of biological samples, whether they are hospitalized or via the outpatient screening channel.
For the main objective: during the D0 visit, the subjects who agreed to participate in the study will have a clinical evaluation according to a standardized questionnaire and a nasopharyngeal swab, saliva, blood, stool and urine.
For secondary objectives : longitudinal follow-up will be carried out for 21 days, for index cases and contact cases, whether they have a positive or negative RT-PCR test on D0. A final consultation will be carried out at M3. Nasopharyngeal samples, saliva, blood, stool and urine will be taken on D10 and D21. A blood test will be taken at M3 to carry out a COVID-19 serology.
研究の種類
介入
入学 (予想される)
100
段階
- 適用できない
連絡先と場所
このセクションには、調査を実施する担当者の連絡先の詳細と、この調査が実施されている場所に関する情報が記載されています。
研究場所
-
-
-
Clermont-Ferrand、フランス、63000
- CHU de Clermont-Ferrand
-
-
参加基準
研究者は、適格基準と呼ばれる特定の説明に適合する人を探します。これらの基準のいくつかの例は、人の一般的な健康状態または以前の治療です。
適格基準
就学可能な年齢
- 子
- 大人
- 高齢者
健康ボランティアの受け入れ
はい
受講資格のある性別
全て
説明
Inclusion Criteria:
- Child or adult, no age limit
- Able to give informed consent to participate in research
- If a minor participant: consent of the legal representatives
- If confirmed case COVID-19 (symptomatic or asymptomatic): laboratory result confirming infection with SARS-CoV-2 by RT-PCR or by serology
- If contact case: people identified as a risk contact according to the criteria of the "Amélie.fr" health insurance
Exclusion Criteria:
- Subjects under tutorship, curatorship, deprived of liberty, safeguard of justice
- Refusal of the child
- Refusal of participation
研究計画
このセクションでは、研究がどのように設計され、研究が何を測定しているかなど、研究計画の詳細を提供します。
研究はどのように設計されていますか？
デザインの詳細
- 主な目的：診断
- 割り当て：なし
- 介入モデル：単一グループの割り当て
- マスキング：なし（オープンラベル）
武器と介入
参加者グループ / アーム |
介入・治療 |
|---|---|
|
実験的：cohort
Biological collection with nasopharyngeal samples, saliva, blood, stool and urine
|
Subjects with a COVID-19 infection and their contact cases (identification according to health insurance criteria, see "Améli.fr") will be offered a clinical evaluation and the takin of biological samples, whether they are hospitalized or via the outpatient screening channel. For the main objective: during the Day0 visit, the subjects who agreed to participate in the study will have a clinical evaluation according to a standardized questionnaire and a nasopharyngeal swab, saliva, blood, stool and urine. For secondary objectives : longitudinal follow-up will be carried out for 21 days, for index cases and contact cases, whether they have a positive or negative RT-PCR test on D0. A final consultation will be carried out at M3. Nasopharyngeal samples, saliva, blood, stool and urine will be taken on D10 and D21. A blood test will be taken at M3 to carry out a COVID-19 serology. |
この研究は何を測定していますか？
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
Virological profile
時間枠：Day 0
|
Nasopharyngeal SARS-CoV-2 viral load at day 0 by RT-PCR (in log or ΔCT)
|
Day 0
|
|
Virological profile
時間枠：Day 10
|
Nasopharyngeal SARS-CoV-2 viral load at day 0 by RT-PCR (in log or ΔCT)
|
Day 10
|
|
Virological profile
時間枠：Day 21
|
Nasopharyngeal SARS-CoV-2 viral load at day 0 by RT-PCR (in log or ΔCT)
|
Day 21
|
|
Virological profile (serology)
時間枠：Day 0
|
SARS-CoV-2 serology by enzyme-linked immunosorbent assays or magnetic chemiluminescence enzyme immunoassay (IgG and IgM titers)
|
Day 0
|
|
Virological profile (serology)
時間枠：Day 10
|
SARS-CoV-2 serology by enzyme-linked immunosorbent assays or magnetic chemiluminescence enzyme immunoassay (IgG and IgM titers)
|
Day 10
|
|
Virological profile (serology)
時間枠：Day 21
|
SARS-CoV-2 serology by enzyme-linked immunosorbent assays or magnetic chemiluminescence enzyme immunoassay (IgG and IgM titers)
|
Day 21
|
|
Immunological profile with blood level for markers of inflammation (cytokine)
時間枠：Day 0
|
cytokine panel by flow cytometry or enzyme-linked immunosorbent assay in pg/mL
|
Day 0
|
|
Immunological profile with blood level for markers of inflammation (cytokine)
時間枠：Day 10
|
cytokine panel by flow cytometry or enzyme-linked immunosorbent assay in pg/mL
|
Day 10
|
|
Immunological profile with blood level for markers of inflammation (cytokine)
時間枠：Day 21
|
cytokine panel by flow cytometry or enzyme-linked immunosorbent assay in pg/mL
|
Day 21
|
|
Immunological profile with blood level for markers of inflammation
時間枠：Day 0
|
markers on immune cell subpopulation by RT-PCR or flow cytometry in CT value or %
|
Day 0
|
|
Immunological profile with blood level for markers of inflammation
時間枠：Day 10
|
markers on immune cell subpopulation by RT-PCR or flow cytometry in CT value or %
|
Day 10
|
|
Immunological profile with blood level for markers of inflammation
時間枠：Day 21
|
markers on immune cell subpopulation by RT-PCR or flow cytometry in CT value or %
|
Day 21
|
|
Biochemical profile by blood dosage of CRP
時間枠：Day 0
|
CRP in mg/l
|
Day 0
|
|
Biochemical profile by blood dosage of CRP
時間枠：Day 10
|
CRP in mg/l
|
Day 10
|
|
Biochemical profile by blood dosage of CRP
時間枠：Day 21
|
CRP in mg/l
|
Day 21
|
|
Biochemical profile by blood dosage of CRP
時間枠：Day 90
|
CRP in mg/l
|
Day 90
|
|
Biochemical profile by blood dosage of ASAT/ALAT
時間枠：Day 0
|
ASAT/ALAT in U/L
|
Day 0
|
|
Biochemical profile by blood dosage of ASAT/ALAT
時間枠：Day 10
|
ASAT/ALAT in U/L
|
Day 10
|
|
Biochemical profile by blood dosage of ASAT/ALAT
時間枠：Day 21
|
ASAT/ALAT in U/L
|
Day 21
|
|
Biochemical profile by blood dosage of ASAT/ALAT
時間枠：Day 90
|
ASAT/ALAT in U/L
|
Day 90
|
|
Biochemical profile by blood dosage of LDH
時間枠：Day 0
|
LDH in U/L
|
Day 0
|
|
Biochemical profile by blood dosage of LDH
時間枠：Day 10
|
LDH in U/L
|
Day 10
|
|
Biochemical profile by blood dosage of LDH
時間枠：Day 21
|
LDH in U/L
|
Day 21
|
|
Biochemical profile by blood dosage of LDH
時間枠：Day 90
|
LDH in U/L
|
Day 90
|
|
Biochemical profile by blood dosage of Lactate
時間枠：Day 0
|
Lactate in mg/l
|
Day 0
|
|
Biochemical profile by blood dosage of Lactate
時間枠：Day 10
|
Lactate in mg/l
|
Day 10
|
|
Biochemical profile by blood dosage of Lactate
時間枠：Day 21
|
Lactate in mg/l
|
Day 21
|
|
Biochemical profile by blood dosage of Lactate
時間枠：Day 90
|
Lactate in mg/l
|
Day 90
|
|
Biochemical profile by blood dosage of D-Dimer
時間枠：Day 0
|
D-Dimer in µg/L
|
Day 0
|
|
Biochemical profile by blood dosage of D-Dimer
時間枠：Day 10
|
D-Dimer in µg/L
|
Day 10
|
|
Biochemical profile by blood dosage of D-Dimer
時間枠：Day 21
|
D-Dimer in µg/L
|
Day 21
|
|
Biochemical profile by blood dosage of D-Dimer
時間枠：Day 90
|
D-Dimer in µg/L
|
Day 90
|
|
Biochemical profile by blood dosage of Troponin
時間枠：Day 0
|
Troponin in µg/L
|
Day 0
|
|
Biochemical profile by blood dosage of Troponin
時間枠：Day 10
|
Troponin in µg/L
|
Day 10
|
|
Biochemical profile by blood dosage of Troponin
時間枠：Day 21
|
Troponin in µg/L
|
Day 21
|
|
Biochemical profile by blood dosage of Troponin
時間枠：Day 90
|
Troponin in µg/L
|
Day 90
|
|
Biochemical profile by blood dosage of Ferritin
時間枠：Day 0
|
Ferritin in µg/L
|
Day 0
|
|
Biochemical profile by blood dosage of Ferritin
時間枠：Day 10
|
Ferritin in µg/L
|
Day 10
|
|
Biochemical profile by blood dosage of Ferritin
時間枠：Day 21
|
Ferritin in µg/L
|
Day 21
|
|
Biochemical profile by blood dosage of RAGE
時間枠：Day 0
|
RAGE (receptor of advanced end glycation products) by enzyme-linked immunosorbent assays in pg/mg total protein
|
Day 0
|
|
Biochemical profile by blood dosage of RAGE
時間枠：Day 10
|
RAGE (receptor of advanced end glycation products) by enzyme-linked immunosorbent assays in pg/mg total protein
|
Day 10
|
|
Biochemical profile by blood dosage of RAGE
時間枠：Day 21
|
RAGE (receptor of advanced end glycation products) by enzyme-linked immunosorbent assays in pg/mg total protein
|
Day 21
|
|
Biochemical profile by blood dosage of SUPAR
時間枠：Day 0
|
SUPAR (soluble urokinase plasminogen activator receptor) by enzyme-linked immunosorbent assays in pg/mg total protein
|
Day 0
|
|
Biochemical profile by blood dosage of SUPAR
時間枠：Day 10
|
SUPAR (soluble urokinase plasminogen activator receptor) by enzyme-linked immunosorbent assays in pg/mg total protein
|
Day 10
|
|
Biochemical profile by blood dosage of SUPAR
時間枠：Day 21
|
SUPAR (soluble urokinase plasminogen activator receptor) by enzyme-linked immunosorbent assays in pg/mg total protein
|
Day 21
|
|
Haematological profile by blood dosage of leukocytes
時間枠：Day 0
|
leukocytes in Giga/L
|
Day 0
|
|
Haematological profile by blood dosage of leukocytes
時間枠：Day 10
|
leukocytes in Giga/L
|
Day 10
|
|
Haematological profile by blood dosage of leukocytes
時間枠：Day 21
|
leukocytes in Giga/L
|
Day 21
|
|
Haematological profile by blood dosage of leukocytes
時間枠：Day 90
|
leukocytes in Giga/L
|
Day 90
|
|
Haematological profile by blood dosage of Red blood cells
時間枠：Day 0
|
Red blood cells in Tera/L
|
Day 0
|
|
Haematological profile by blood dosage of Red blood cells
時間枠：Day 10
|
Red blood cells in Tera/L
|
Day 10
|
|
Haematological profile by blood dosage of Red blood cells
時間枠：Day 21
|
Red blood cells in Tera/L
|
Day 21
|
|
Haematological profile by blood dosage of Red blood cells
時間枠：Day 90
|
Red blood cells in Tera/L
|
Day 90
|
|
Haematological profile by blood dosage of Hemoglobin
時間枠：Day 0
|
Hemoglobin in g/dL
|
Day 0
|
|
Haematological profile by blood dosage of Hemoglobin
時間枠：Day 10
|
Hemoglobin in g/dL
|
Day 10
|
|
Haematological profile by blood dosage of Hemoglobin
時間枠：Day 21
|
Hemoglobin in g/dL
|
Day 21
|
|
Haematological profile by blood dosage of Hemoglobin
時間枠：Day 90
|
Hemoglobin in g/dL
|
Day 90
|
|
Haematological profile by blood dosage of Hematocrit
時間枠：Day 0
|
Hematocrit in %
|
Day 0
|
|
Haematological profile by blood dosage of Hematocrit
時間枠：Day 10
|
Hematocrit in %
|
Day 10
|
|
Haematological profile by blood dosage of Hematocrit
時間枠：Day 21
|
Hematocrit in %
|
Day 21
|
|
Haematological profile by blood dosage of Hematocrit
時間枠：Day 90
|
Hematocrit in %
|
Day 90
|
|
Haematological profile by blood dosage of Mean corpuscular volume
時間枠：Day 0
|
Mean corpuscular volume in fL
|
Day 0
|
|
Haematological profile by blood dosage of Mean corpuscular volume
時間枠：Day 10
|
Mean corpuscular volume in fL
|
Day 10
|
|
Haematological profile by blood dosage of Mean corpuscular volume
時間枠：Day 21
|
Mean corpuscular volume in fL
|
Day 21
|
|
Haematological profile by blood dosage of Mean corpuscular volume
時間枠：Day 90
|
Mean corpuscular volume in fL
|
Day 90
|
|
Haematological profile by blood dosage of Mean corpuscular hemoglobin
時間枠：Day 0
|
Mean corpuscular hemoglobin in pg
|
Day 0
|
|
Haematological profile by blood dosage of Mean corpuscular hemoglobin
時間枠：Day 10
|
Mean corpuscular hemoglobin in pg
|
Day 10
|
|
Haematological profile by blood dosage of Mean corpuscular hemoglobin
時間枠：Day 21
|
Mean corpuscular hemoglobin in pg
|
Day 21
|
|
Haematological profile by blood dosage of Mean corpuscular hemoglobin
時間枠：Day 90
|
Mean corpuscular hemoglobin in pg
|
Day 90
|
|
Haematological profile by blood dosage of average corpuscular concentration of haemoglobin
時間枠：Day 0
|
Average corpuscular concentration of haemoglobin in g/dL
|
Day 0
|
|
Haematological profile by blood dosage of average corpuscular concentration of haemoglobin
時間枠：Day 10
|
Average corpuscular concentration of haemoglobin in g/dL
|
Day 10
|
|
Haematological profile by blood dosage of average corpuscular concentration of haemoglobin
時間枠：Day 21
|
Average corpuscular concentration of haemoglobin in g/dL
|
Day 21
|
|
Haematological profile by blood dosage of average corpuscular concentration of haemoglobin
時間枠：Day 90
|
Average corpuscular concentration of haemoglobin in g/dL
|
Day 90
|
|
Haematological profile by blood dosage of polynuclear neutrophil
時間枠：Day 0
|
polynuclear neutrophil in Giga/L
|
Day 0
|
|
Haematological profile by blood dosage of polynuclear neutrophil
時間枠：Day 10
|
polynuclear neutrophil in Giga/L
|
Day 10
|
|
Haematological profile by blood dosage of polynuclear neutrophil
時間枠：Day 21
|
polynuclear neutrophil in Giga/L
|
Day 21
|
|
Haematological profile by blood dosage of polynuclear neutrophil
時間枠：Day 90
|
polynuclear neutrophil in Giga/L
|
Day 90
|
|
Haematological profile by blood dosage of polynuclear eosinophils
時間枠：Day 0
|
polynuclear eosinophils in Giga/L
|
Day 0
|
|
Haematological profile by blood dosage of polynuclear eosinophils
時間枠：Day 10
|
polynuclear eosinophils in Giga/L
|
Day 10
|
|
Haematological profile by blood dosage of polynuclear eosinophils
時間枠：Day 21
|
polynuclear eosinophils in Giga/L
|
Day 21
|
|
Haematological profile by blood dosage of polynuclear eosinophils
時間枠：Day 90
|
polynuclear eosinophils in Giga/L
|
Day 90
|
|
Haematological profile by blood dosage of polynuclear basophils
時間枠：Day 0
|
polynuclear basophils in Giga/L
|
Day 0
|
|
Haematological profile by blood dosage of polynuclear basophils
時間枠：Day 10
|
polynuclear basophils in Giga/L
|
Day 10
|
|
Haematological profile by blood dosage of polynuclear basophils
時間枠：Day 21
|
polynuclear basophils in Giga/L
|
Day 21
|
|
Haematological profile by blood dosage of polynuclear basophils
時間枠：Day 90
|
polynuclear basophils in Giga/L
|
Day 90
|
|
Haematological profile by blood dosage of lymphocytes
時間枠：Day 0
|
lymphocytes in Giga/L
|
Day 0
|
|
Haematological profile by blood dosage of lymphocytes
時間枠：Day 10
|
lymphocytes in Giga/L
|
Day 10
|
|
Haematological profile by blood dosage of lymphocytes
時間枠：Day 21
|
lymphocytes in Giga/L
|
Day 21
|
|
Haematological profile by blood dosage of lymphocytes
時間枠：Day 90
|
lymphocytes in Giga/L
|
Day 90
|
|
Haematological profile by blood dosage of monocytes
時間枠：Day 90
|
monocytes in Giga/L
|
Day 90
|
|
Haematological profile by blood dosage of monocytes
時間枠：Day 0
|
monocytes in Giga/L
|
Day 0
|
|
Haematological profile by blood dosage of monocytes
時間枠：Day 10
|
monocytes in Giga/L
|
Day 10
|
|
Haematological profile by blood dosage of monocytes
時間枠：Day 21
|
monocytes in Giga/L
|
Day 21
|
|
Haematological profile by blood dosage of platelets
時間枠：Day 0
|
platelets in Giga/L
|
Day 0
|
|
Haematological profile by blood dosage of platelets
時間枠：Day 10
|
platelets in Giga/L
|
Day 10
|
|
Haematological profile by blood dosage of platelets
時間枠：Day 21
|
platelets in Giga/L
|
Day 21
|
|
Haematological profile by blood dosage of platelets
時間枠：Day 90
|
platelets in Giga/L
|
Day 90
|
|
Haematological profile by blood dosage of activated partial thromboplastin time
時間枠：Day 0
|
activated partial thromboplastin time in second/witness
|
Day 0
|
|
Haematological profile by blood dosage of activated partial thromboplastin time
時間枠：Day 10
|
activated partial thromboplastin time in second/witness
|
Day 10
|
|
Haematological profile by blood dosage of activated partial thromboplastin time
時間枠：Day 21
|
activated partial thromboplastin time in second/witness
|
Day 21
|
|
Haematological profile by blood dosage of activated partial thromboplastin time
時間枠：Day 90
|
activated partial thromboplastin time in second/witness
|
Day 90
|
|
Haematological profile by blood dosage of fibrinogen
時間枠：Day 0
|
fibrinogen in g/L
|
Day 0
|
|
Haematological profile by blood dosage of fibrinogen
時間枠：Day 10
|
fibrinogen in g/L
|
Day 10
|
|
Haematological profile by blood dosage of fibrinogen
時間枠：Day 21
|
fibrinogen in g/L
|
Day 21
|
|
Haematological profile by blood dosage of fibrinogen
時間枠：Day 90
|
fibrinogen in g/L
|
Day 90
|
|
Haematological profile by blood dosage of factor V
時間枠：Day 0
|
factor V in %
|
Day 0
|
|
Haematological profile by blood dosage of factor V
時間枠：Day 10
|
factor V in %
|
Day 10
|
|
Haematological profile by blood dosage of factor V
時間枠：Day 21
|
factor V in %
|
Day 21
|
|
Haematological profile by blood dosage of factor V
時間枠：Day 90
|
factor V in %
|
Day 90
|
二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
SARS-CoV-2 salivary viral load
時間枠：Day 0
|
RT-PCR SARS-CoV-2 on saliva in ΔCT value or log10 copies per mL
|
Day 0
|
|
SARS-CoV-2 salivary viral load
時間枠：Day 10
|
RT-PCR SARS-CoV-2 on saliva in ΔCT value or log10 copies per mL
|
Day 10
|
|
SARS-CoV-2 salivary viral load
時間枠：Day 21
|
RT-PCR SARS-CoV-2 on saliva in ΔCT value or log10 copies per mL
|
Day 21
|
|
Comparison of viral sequences
時間枠：Day 0
|
bioinformatic and statistical analyzes of viral sequences (arbitrary unit and p-values)
|
Day 0
|
|
Comparison of viral sequences
時間枠：Day 10
|
bioinformatic and statistical analyzes of viral sequences (arbitrary unit and p-values)
|
Day 10
|
|
Comparison of viral sequences
時間枠：Day 21
|
bioinformatic and statistical analyzes of viral sequences (arbitrary unit and p-values)
|
Day 21
|
|
microbiota analysis
時間枠：Day 0
|
bioinformatic and statistical analyzes of microbiota (arbitrary unit and p-values)
|
Day 0
|
|
microbiota analysis
時間枠：Day 10
|
bioinformatic and statistical analyzes of microbiota (arbitrary unit and p-values)
|
Day 10
|
|
microbiota analysis
時間枠：Day 21
|
bioinformatic and statistical analyzes of microbiota (arbitrary unit and p-values)
|
Day 21
|
|
environmental and societal factors (EPICE)
時間枠：Day 0
|
EPICE score (Assessment of precariousness and health inequalities in examination centers Health) at day 0 from 0 to 100
|
Day 0
|
|
environmental and societal factors
時間枠：Day 0
|
eating habits
|
Day 0
|
|
environmental and societal factors
時間枠：day 10
|
eating habits
|
day 10
|
|
environmental and societal factors
時間枠：day 21
|
eating habits
|
day 21
|
|
environmental and societal factors
時間枠：day 90
|
eating habits
|
day 90
|
|
environmental and societal factors (SF-36)
時間枠：Day 0
|
SF-36 score (quality of life by Gardenal O) from 0 to 100
|
Day 0
|
|
environmental and societal factors (SF-36)
時間枠：day 10
|
SF-36 score (quality of life by Gardenal O) from 0 to 100
|
day 10
|
|
environmental and societal factors (SF-36)
時間枠：day 21
|
SF-36 score (quality of life by Gardenal O) from 0 to 100
|
day 21
|
|
environmental and societal factors (SF-36)
時間枠：day 90
|
SF-36 score (quality of life by Gardenal O) from 0 to 100
|
day 90
|
|
environmental and societal factors (Physical activity)
時間枠：Day 0
|
Physical activity score (by J. Ricci et L. Gagnon test for adults and ActiFitY test for children) from 0 to 100
|
Day 0
|
|
environmental and societal factors (Physical activity)
時間枠：day 10
|
Physical activity score (by J. Ricci et L. Gagnon test for adults and ActiFitY test for children) from 0 to 100
|
day 10
|
|
environmental and societal factors (Physical activity)
時間枠：day 21
|
Physical activity score (by J. Ricci et L. Gagnon test for adults and ActiFitY test for children) from 0 to 100
|
day 21
|
|
environmental and societal factors (Physical activity)
時間枠：day 90
|
Physical activity score (by J. Ricci et L. Gagnon test for adults and ActiFitY test for children) from 0 to 100
|
day 90
|
|
body weight
時間枠：Day 0
|
body weight in kg
|
Day 0
|
|
body weight
時間枠：day 10
|
body weight in kg
|
day 10
|
|
body weight
時間枠：day 21
|
body weight in kg
|
day 21
|
|
body weight
時間枠：day 90
|
body weight in kg
|
day 90
|
|
oxygen saturation
時間枠：Day 0
|
oxygen saturation in %
|
Day 0
|
|
oxygen saturation
時間枠：day 10
|
oxygen saturation in %
|
day 10
|
|
oxygen saturation
時間枠：day 21
|
oxygen saturation in %
|
day 21
|
|
oxygen saturation
時間枠：day 90
|
oxygen saturation in %
|
day 90
|
|
Respiratory rate
時間枠：Day 0
|
Respiratory rate per minute
|
Day 0
|
|
Respiratory rate
時間枠：day 10
|
Respiratory rate per minute
|
day 10
|
|
Respiratory rate
時間枠：day 21
|
Respiratory rate per minute
|
day 21
|
|
Respiratory rate
時間枠：day 90
|
Respiratory rate per minute
|
day 90
|
|
cardiac frequency
時間枠：Day 0
|
cardiac frequency per minute
|
Day 0
|
|
cardiac frequency
時間枠：day 10
|
cardiac frequency per minute
|
day 10
|
|
cardiac frequency
時間枠：day 21
|
cardiac frequency per minute
|
day 21
|
|
cardiac frequency
時間枠：day 90
|
cardiac frequency per minute
|
day 90
|
|
lung damage
時間枠：Day 0
|
Lung damage on auscultation in terms of presence/absence
|
Day 0
|
|
lung damage
時間枠：day 10
|
Lung damage on auscultation in terms of presence/absence
|
day 10
|
|
lung damage
時間枠：day 21
|
Lung damage on auscultation in terms of presence/absence
|
day 21
|
|
lung damage
時間枠：day 90
|
Lung damage on auscultation in terms of presence/absence
|
day 90
|
|
lung evolution
時間枠：day 90
|
CT san in terms of normal/abnormal (children and pregnant women not concerned)
|
day 90
|
|
blood pressure
時間枠：Day 0
|
Dysatolic/systolic blood pressure in mmHg
|
Day 0
|
|
blood pressure
時間枠：day 10
|
Dysatolic/systolic blood pressure in mmHg
|
day 10
|
|
blood pressure
時間枠：day 21
|
Dysatolic/systolic blood pressure in mmHg
|
day 21
|
|
blood pressure
時間枠：day 90
|
Dysatolic/systolic blood pressure in mmHg
|
day 90
|
|
body temperature
時間枠：Day 0
|
Body temperature in °C
|
Day 0
|
|
body temperature
時間枠：day 10
|
Body temperature in °C
|
day 10
|
|
body temperature
時間枠：day 21
|
Body temperature in °C
|
day 21
|
|
body temperature
時間枠：day 90
|
Body temperature in °C
|
day 90
|
|
clinical exam (skin)
時間枠：Day 0
|
Skin mottling in terms of presence/absence
|
Day 0
|
|
clinical exam (skin)
時間枠：day 10
|
Skin mottling in terms of presence/absence
|
day 10
|
|
clinical exam (skin)
時間枠：day 21
|
Skin mottling in terms of presence/absence
|
day 21
|
|
clinical exam (skin)
時間枠：day 90
|
Skin mottling in terms of presence/absence
|
day 90
|
|
clinical exam (polypnea)
時間枠：Day 0
|
polypnea in terms of presence/absence
|
Day 0
|
|
clinical exam (polypnea)
時間枠：day 10
|
polypnea in terms of presence/absence
|
day 10
|
|
clinical exam (polypnea)
時間枠：day 21
|
polypnea in terms of presence/absence
|
day 21
|
|
clinical exam (polypnea)
時間枠：day 90
|
polypnea in terms of presence/absence
|
day 90
|
|
denutrition
時間枠：Day 0
|
denutrition in terms of presence/absence
|
Day 0
|
|
denutrition
時間枠：day 10
|
denutrition in terms of presence/absence
|
day 10
|
|
denutrition
時間枠：day 21
|
denutrition in terms of presence/absence
|
day 21
|
|
denutrition
時間枠：day 90
|
denutrition in terms of presence/absence
|
day 90
|
|
Antibiotic treatment
時間枠：Day 0
|
Antibiotic treatment in terms of presence/absence with precision if necessary
|
Day 0
|
|
Antibiotic treatment
時間枠：day 10
|
Antibiotic treatment in terms of presence/absence with precision if necessary
|
day 10
|
|
Antibiotic treatment
時間枠：day 21
|
Antibiotic treatment in terms of presence/absence with precision if necessary
|
day 21
|
|
Antibiotic treatment
時間枠：day 90
|
Antibiotic treatment in terms of presence/absence with precision if necessary
|
day 90
|
|
Steroidal anti-inflammatory treatment
時間枠：Day 0
|
Steroidal anti-inflammatory treatment in terms of presence/absence with precision if necessary
|
Day 0
|
|
Steroidal anti-inflammatory treatment
時間枠：day 10
|
Steroidal anti-inflammatory treatment in terms of presence/absence with precision if necessary
|
day 10
|
|
Steroidal anti-inflammatory treatment
時間枠：day 21
|
Steroidal anti-inflammatory treatment in terms of presence/absence with precision if necessary
|
day 21
|
|
Steroidal anti-inflammatory treatment
時間枠：day 90
|
Steroidal anti-inflammatory treatment in terms of presence/absence with precision if necessary
|
day 90
|
|
Anti-diabetic treatment
時間枠：Day 0
|
Anti-diabetic treatment in terms of presence/absence with precision if necessary
|
Day 0
|
|
Anti-diabetic treatment
時間枠：day 10
|
Anti-diabetic treatment in terms of presence/absence with precision if necessary
|
day 10
|
|
Anti-diabetic treatment
時間枠：day 21
|
Anti-diabetic treatment in terms of presence/absence with precision if necessary
|
day 21
|
|
Anti-diabetic treatment
時間枠：day 90
|
Anti-diabetic treatment in terms of presence/absence with precision if necessary
|
day 90
|
|
Gastric protector treatment
時間枠：Day 0
|
Gastric protector treatment in terms of presence/absence with precision if necessary
|
Day 0
|
|
Gastric protector treatment
時間枠：day 10
|
Gastric protector treatment in terms of presence/absence with precision if necessary
|
day 10
|
|
Gastric protector treatment
時間枠：day 21
|
Gastric protector treatment in terms of presence/absence with precision if necessary
|
day 21
|
|
Gastric protector treatment
時間枠：day 90
|
Gastric protector treatment in terms of presence/absence with precision if necessary
|
day 90
|
|
chills
時間枠：Day 0
|
chills in terms of presence/absence
|
Day 0
|
|
chills
時間枠：day 10
|
chills in terms of presence/absence
|
day 10
|
|
chills
時間枠：day 21
|
chills in terms of presence/absence
|
day 21
|
|
chills
時間枠：day 90
|
chills in terms of presence/absence
|
day 90
|
|
Myalgia
時間枠：Day 0
|
Myalgia in terms of presence/absence
|
Day 0
|
|
Myalgia
時間枠：day 10
|
Myalgia in terms of presence/absence
|
day 10
|
|
Myalgia
時間枠：day 21
|
Myalgia in terms of presence/absence
|
day 21
|
|
Myalgia
時間枠：day 90
|
Myalgia in terms of presence/absence
|
day 90
|
|
Anorexia
時間枠：Day 0
|
Anorexia in terms of presence/absence
|
Day 0
|
|
Anorexia
時間枠：day 10
|
Anorexia in terms of presence/absence
|
day 10
|
|
Anorexia
時間枠：day 21
|
Anorexia in terms of presence/absence
|
day 21
|
|
Anorexia
時間枠：day 90
|
Anorexia in terms of presence/absence
|
day 90
|
|
Rhinitis
時間枠：Day 0
|
Rhinitis in terms of presence/absence
|
Day 0
|
|
Rhinitis
時間枠：day 10
|
Rhinitis in terms of presence/absence
|
day 10
|
|
Rhinitis
時間枠：day 21
|
Rhinitis in terms of presence/absence
|
day 21
|
|
Rhinitis
時間枠：day 90
|
Rhinitis in terms of presence/absence
|
day 90
|
|
Confusion
時間枠：Day 0
|
Confusion in terms of presence/absence
|
Day 0
|
|
Confusion
時間枠：day 10
|
Confusion in terms of presence/absence
|
day 10
|
|
Confusion
時間枠：day 21
|
Confusion in terms of presence/absence
|
day 21
|
|
Confusion
時間枠：day 90
|
Confusion in terms of presence/absence
|
day 90
|
|
Asthenia
時間枠：Day 0
|
Asthenia in terms of presence/absence
|
Day 0
|
|
Asthenia
時間枠：day 10
|
Asthenia in terms of presence/absence
|
day 10
|
|
Asthenia
時間枠：day 21
|
Asthenia in terms of presence/absence
|
day 21
|
|
Asthenia
時間枠：day 90
|
Asthenia in terms of presence/absence
|
day 90
|
|
Falls at home
時間枠：Day 0
|
Falls at home in terms of presence/absence
|
Day 0
|
|
Falls at home
時間枠：day 10
|
Falls at home in terms of presence/absence
|
day 10
|
|
Falls at home
時間枠：day 21
|
Falls at home in terms of presence/absence
|
day 21
|
|
Falls at home
時間枠：day 90
|
Falls at home in terms of presence/absence
|
day 90
|
|
Insomnia
時間枠：Day 0
|
Insomnia in terms of presence/absence
|
Day 0
|
|
Insomnia
時間枠：day 10
|
Insomnia in terms of presence/absence
|
day 10
|
|
Insomnia
時間枠：day 21
|
Insomnia in terms of presence/absence
|
day 21
|
|
Insomnia
時間枠：day 90
|
Insomnia in terms of presence/absence
|
day 90
|
|
Angina
時間枠：Day 0
|
Angina in terms of presence/absence
|
Day 0
|
|
Angina
時間枠：day 10
|
Angina in terms of presence/absence
|
day 10
|
|
Angina
時間枠：day 21
|
Angina in terms of presence/absence
|
day 21
|
|
Angina
時間枠：day 90
|
Angina in terms of presence/absence
|
day 90
|
|
Ageusia
時間枠：Day 0
|
Ageusia in terms of presence/absence
|
Day 0
|
|
Ageusia
時間枠：day 10
|
Ageusia in terms of presence/absence
|
day 10
|
|
Ageusia
時間枠：day 21
|
Ageusia in terms of presence/absence
|
day 21
|
|
Ageusia
時間枠：day 90
|
Ageusia in terms of presence/absence
|
day 90
|
|
Respiratory complaints
時間枠：Day 0
|
Respiratory complaints in term of SRIpr score from 0 to 100
|
Day 0
|
|
Respiratory complaints
時間枠：day 2
|
Respiratory complaints in term of SRIpr score from 0 to 100
|
day 2
|
|
Respiratory complaints
時間枠：day 4
|
Respiratory complaints in term of SRIpr score from 0 to 100
|
day 4
|
|
Respiratory complaints
時間枠：day 6
|
Respiratory complaints in term of SRIpr score from 0 to 100
|
day 6
|
|
Respiratory complaints
時間枠：day 8
|
Respiratory complaints in term of SRIpr score from 0 to 100
|
day 8
|
|
Respiratory complaints
時間枠：day 10
|
Respiratory complaints in term of SRIpr score from 0 to 100
|
day 10
|
|
Respiratory complaints
時間枠：day 21
|
Respiratory complaints in term of SRIpr score from 0 to 100
|
day 21
|
|
Respiratory complaints
時間枠：day 90
|
Respiratory complaints in term of SRIpr score from 0 to 100
|
day 90
|
|
transmission rate
時間枠：Day 0
|
Rate of viral transmission determine by bioinformatic and statistical analyzes in %
|
Day 0
|
|
transmission rate
時間枠：day 10
|
Rate of viral transmission determine by bioinformatic and statistical analyzes in %
|
day 10
|
|
transmission rate
時間枠：day 21
|
Rate of viral transmission determine by bioinformatic and statistical analyzes in %
|
day 21
|
|
prolonged viral shedding
時間枠：between day 0 and day 21
|
Prolonged viral shedding evaluate by RT-PCR (CT value or log10 copies per mL)
|
between day 0 and day 21
|
協力者と研究者
ここでは、この調査に関係する人々や組織を見つけることができます。
捜査官
- 主任研究者：Céclie Henquell、University Hospital, Clermont-Ferrand
研究記録日
これらの日付は、ClinicalTrials.gov への研究記録と要約結果の提出の進捗状況を追跡します。研究記録と報告された結果は、国立医学図書館 (NLM) によって審査され、公開 Web サイトに掲載される前に、特定の品質管理基準を満たしていることが確認されます。
主要日程の研究
研究開始 (予想される)
2020年11月1日
一次修了 (予想される)
2021年11月1日
研究の完了 (予想される)
2022年2月1日
試験登録日
最初に提出
2020年10月2日
QC基準を満たした最初の提出物
2020年10月21日
最初の投稿 (実際)
2020年10月22日
学習記録の更新
投稿された最後の更新 (実際)
2020年10月22日
QC基準を満たした最後の更新が送信されました
2020年10月21日
最終確認日
2020年9月1日
詳しくは
本研究に関する用語
追加の関連 MeSH 用語
その他の研究ID番号
- RBPH 2020 HENQUELL
- 2020-A02381-38 (その他の識別子：ANSM)
医薬品およびデバイス情報、研究文書
米国FDA規制医薬品の研究
いいえ
米国FDA規制機器製品の研究
いいえ
この情報は、Web サイト clinicaltrials.gov から変更なしで直接取得したものです。研究の詳細を変更、削除、または更新するリクエストがある場合は、register@clinicaltrials.gov。 までご連絡ください。 clinicaltrials.gov に変更が加えられるとすぐに、ウェブサイトでも自動的に更新されます。