Comparison Of Early Mobilization And Electrical Stimulation On Functional Recovery After Lumbar Disc Herniation Surgery (EMES-LDH)
Comparison Of Early Mobilization And Electrical Stimulation-Supported Rehabilitation On Functional Recovery, Pain Level, And Mobility After Lumbar Disc Herniation Surgery: A Prospective Randomized Controlled Trial
This randomized controlled trial aims to compare the effectiveness of early mobilization alone versus early mobilization combined with electrical stimulation on functional recovery following lumbar disc herniation surgery. Lumbar disc herniation is a common cause of low back pain and functional limitation, significantly affecting quality of life.
Although surgical intervention is effective in patients who do not respond to conservative treatment, optimal postoperative recovery largely depends on appropriate rehabilitation strategies. Early mobilization is widely recommended to prevent complications, preserve muscle function, and facilitate return to daily activities. In addition, electrical stimulation modalities such as neuromuscular electrical stimulation (NMES) and transcutaneous electrical nerve stimulation (TENS) have been increasingly integrated into rehabilitation programs to enhance pain control, muscle activation, and neuromuscular re-education.
In this study, a total of 60 participants who have undergone primary lumbar disc herniation surgery will be randomly assigned into two groups. The first group will receive an early mobilization program alone, while the second group will receive early mobilization combined with electrical stimulation (NMES/TENS). The intervention period will last 6 to 8 weeks, with sessions conducted three times per week.
Primary outcomes include functional disability measured by the Oswestry Disability Index (ODI) and pain intensity measured by the Visual Analog Scale (VAS). Secondary outcomes include functional mobility assessed by the Timed Up and Go (TUG) test, walking speed assessed by the 10-Meter Walk Test (10MWT), and muscle strength evaluated using manual muscle testing (MMT).
The findings of this study are expected to contribute to the development of evidence-based postoperative rehabilitation protocols and to clarify the clinical effectiveness of electrical stimulation in patients undergoing lumbar disc herniation surgery
調査の概要
状態
詳細な説明
Lumbar disc herniation is one of the most prevalent musculoskeletal conditions leading to low back pain, disability, and reduced functional capacity in adults. Surgical treatment is commonly indicated in patients with persistent symptoms or neurological deficits who do not respond to conservative management. Despite successful surgical intervention, postoperative recovery outcomes vary considerably and are highly influenced by rehabilitation strategies.
Early mobilization is considered a cornerstone of postoperative rehabilitation, as it reduces the risk of complications such as deep vein thrombosis, muscle atrophy, and joint stiffness. It also promotes faster recovery of functional independence and return to daily activities. However, early mobilization alone may not be sufficient to optimize neuromuscular recovery and pain management in all patients.
Electrical stimulation modalities, including neuromuscular electrical stimulation (NMES) and transcutaneous electrical nerve stimulation (TENS), have been increasingly utilized in rehabilitation settings. NMES facilitates muscle activation and prevents disuse atrophy, while TENS is widely used for pain modulation through neurophysiological mechanisms such as gate control theory. These modalities may provide additional benefits when combined with conventional rehabilitation approaches.
However, there is a limited number of high-quality randomized controlled trials directly comparing early mobilization alone with electrical stimulation-supported rehabilitation in patients following lumbar disc herniation surgery. This gap in the literature highlights the need for well-designed clinical trials to guide evidence-based practice.
Study Design
This study is designed as a prospective, two-arm, parallel-group randomized controlled trial. Participants will be randomly allocated using a computer-generated randomization method into one of two groups:
Group 1: Early mobilization program Group 2: Early mobilization combined with electrical stimulation (NMES/TENS) Intervention Protocol Both groups will participate in a structured rehabilitation program conducted three times per week for 6-8 weeks. The early mobilization program will include gradual ambulation, posture training, range of motion exercises, and functional activity training.
In the intervention group, electrical stimulation will be applied to paraspinal and lower extremity muscle groups. The parameters of NMES and TENS will be adjusted based on patient tolerance and clinical indications.
Outcome Measures Assessments will be performed at baseline (pre-intervention) and after completion of the intervention program.
Primary Outcomes:
Functional disability: Oswestry Disability Index (ODI) Pain intensity: Visual Analog Scale (VAS)
Secondary Outcomes:
Functional mobility: Timed Up and Go (TUG) test Walking speed: 10-Meter Walk Test (10MWT) Muscle strength: Manual Muscle Testing (MMT) Eligibility Criteria Participants aged between 18 and 65 years who have undergone primary lumbar disc herniation surgery and are in the early postoperative period (within the first 2 weeks) will be included. Patients with previous spinal surgery, severe neurological deficits, contraindications to electrical stimulation (e.g., pacemaker), or serious systemic diseases will be excluded.
Statistical Analysis Data will be analyzed using IBM SPSS Statistics software. Normality will be assessed using the Shapiro-Wilk test. Between-group comparisons will be performed using independent samples t-test or Mann-Whitney U test, while within-group comparisons will be analyzed using paired samples t-test or Wilcoxon signed-rank test. A two-way repeated measures ANOVA will be used to evaluate group-by-time interactions. A p-value of less than 0.05 will be considered statistically significant.
Expected Outcomes and Significance This study aims to provide high-quality evidence regarding the comparative effectiveness of early mobilization and electrical stimulation-supported rehabilitation. The results are expected to support clinical decision-making, optimize postoperative rehabilitation protocols, and contribute to the advancement of evidence-based physiotherapy practices.
研究の種類
入学 (推定)
段階
- 適用できない
連絡先と場所
研究連絡先
- 名前:Mehmet Salih TAN, Doctorate
- 電話番号:+905467266876
- メール:mstan@medipol.edu.tr
参加基準
適格基準
就学可能な年齢
- 大人
- 高齢者
健康ボランティアの受け入れ
説明
Inclusion Criteria:
- Age between 18 and 65 years
- Patients who have undergone primary lumbar disc herniation surgery
- Being in the early postoperative period (within the first 2 weeks after surgery)
- Clinically stable condition
- Ability to understand and follow instructions
- Willingness to participate in the study and provide informed consent
Exclusion Criteria:
- History of previous spinal surgery
- Presence of severe neurological deficits (e.g., progressive motor loss, cauda equina syndrome)
- Contraindications to electrical stimulation (e.g., pacemaker, implanted electronic devices)
- Presence of severe systemic or uncontrolled chronic diseases (e.g., severe cardiovascular, respiratory, or metabolic disorders)
- Cognitive impairment or inability to cooperate with rehabilitation program Pregnancy
研究計画
研究はどのように設計されていますか?
デザインの詳細
- 主な目的:処理
- 割り当て:ランダム化
- 介入モデル:並列代入
- マスキング:独身
武器と介入
参加者グループ / アーム |
介入・治療 |
|---|---|
|
実験的:Early Mobilization + Electrical Stimulation
Participants in this group will receive the same early mobilization program combined with electrical stimulation (NMES and/or TENS).
Electrical stimulation will be applied to paraspinal and lower extremity muscle groups based on patient tolerance and clinical indications.
The rehabilitation program will be conducted three times per week for 6-8 weeks.
|
A structured early mobilization program initiated in the early postoperative period following lumbar disc herniation surgery.
The program includes gradual ambulation, posture training, range of motion exercises, and functional activity training.
Sessions will be conducted three times per week for 6-8 weeks.
The program is designed to improve functional recovery, mobility, and independence in daily activities.
Electrical stimulation will be applied as an adjunct to early mobilization in the postoperative rehabilitation of lumbar disc herniation.
Neuromuscular electrical stimulation (NMES) will be used to facilitate muscle activation and prevent muscle atrophy, while transcutaneous electrical nerve stimulation (TENS) will be used for pain modulation.
Stimulation will be applied to paraspinal and lower extremity muscle groups according to patient tolerance and clinical indications.
Sessions will be conducted three times per week for 6-8 weeks.
|
|
アクティブコンパレータ:Early Mobilization
Participants in this group will receive a structured early mobilization program following lumbar disc herniation surgery.
The program will include gradual ambulation, posture training, range of motion exercises, and functional activity training.
Sessions will be conducted three times per week for 6-8 weeks.
No electrical stimulation will be applied in this group
|
A structured early mobilization program initiated in the early postoperative period following lumbar disc herniation surgery.
The program includes gradual ambulation, posture training, range of motion exercises, and functional activity training.
Sessions will be conducted three times per week for 6-8 weeks.
The program is designed to improve functional recovery, mobility, and independence in daily activities.
|
この研究は何を測定していますか?
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
Oswestry Disability Index (ODI)
時間枠:Baseline (pre-intervention) and 8 weeks post-intervention
|
The Oswestry Disability Index (ODI) will be used to evaluate functional disability related to low back pain following lumbar disc herniation surgery.
The questionnaire consists of 10 sections assessing activities of daily living including pain intensity, personal care, lifting, walking, sitting, standing, sleeping, social life, and traveling.
Each section is scored from 0 to 5, and total scores are expressed as a percentage, with higher scores indicating greater disability.
|
Baseline (pre-intervention) and 8 weeks post-intervention
|
|
Visual Analog Scale (VAS) for Pain
時間枠:Baseline (pre-intervention) and 8 weeks post-intervention
|
Pain intensity will be assessed using the Visual Analog Scale (VAS), a 10 cm horizontal line ranging from 0 (no pain) to 10 (worst imaginable pain).
Participants will mark their perceived pain level.
The VAS is widely used for both acute and chronic pain assessment and is highly sensitive to clinical change.
|
Baseline (pre-intervention) and 8 weeks post-intervention
|
二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
Timed Up and Go Test (TUG)
時間枠:Baseline and 8 weeks post-intervention
|
The Timed Up and Go (TUG) test will be used to assess functional mobility and balance.
Participants will rise from a standard chair, walk 3 meters, turn, return, and sit down.
The time in seconds will be recorded, with lower times indicating better functional mobility.
|
Baseline and 8 weeks post-intervention
|
|
10-Meter Walk Test (10MWT)
時間枠:Baseline and 8 weeks post-intervention
|
Walking speed will be evaluated using the 10-Meter Walk Test.
Participants will walk a 10-meter distance at a comfortable pace, and time will be recorded.
Walking speed (m/s) will be calculated, with higher values indicating better functional ambulation capacity.
|
Baseline and 8 weeks post-intervention
|
|
Manual Muscle Testing (MMT)
時間枠:Baseline and 8 weeks post-intervention
|
Muscle strength will be assessed using Manual Muscle Testing (MMT), graded on a 0-5 scale.
A score of 0 indicates no muscle contraction, while 5 indicates normal muscle strength.
Key muscle groups of the lower extremity and paraspinal region will be evaluated.
|
Baseline and 8 weeks post-intervention
|
協力者と研究者
研究記録日
主要日程の研究
研究開始 (推定)
一次修了 (推定)
研究の完了 (推定)
試験登録日
最初に提出
QC基準を満たした最初の提出物
最初の投稿 (実際)
学習記録の更新
投稿された最後の更新 (実際)
QC基準を満たした最後の更新が送信されました
最終確認日
詳しくは
本研究に関する用語
追加の関連 MeSH 用語
その他の研究ID番号
- LDH-EMES-2026
- Medipol-PT-2026-05 (その他の識別子:Istanbul Medipol Universtiy)
個々の参加者データ (IPD) の計画
個々の参加者データ (IPD) を共有する予定はありますか?
IPD プランの説明
医薬品およびデバイス情報、研究文書
米国FDA規制医薬品の研究
米国FDA規制機器製品の研究
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