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Combined Effects of Aerobic Exercise and Strength Training Among Post CABG Patients

2026年7月17日 更新者：Riphah International University

Combined Effects of Aerobic Exercise and Strength Training on Functional Capacity, Cardiorespiratory Fitness and Quality of Life With Cardiac Rehabilitation Phase II Among Post CABG Patients

Title of study Combined effects aerobic exercise and strength training on functional capacity, cardiorespiratory fitness and quality of life with cardiac rehabilitation phase II among post CABG patients Objective (s) of the study To investigate the combined effects of aerobic exercise and strength training on functional capacity, cardiorespiratory fitness and quality of life with cardiac rehabilitation phase II among post CABG patients.

Methodology (Design, sample size, sampling technique, Study setting, inclusion and exclusion criteria and Tool) Design: Randomized Controlled Trial Sample Size: 42 patients Sampling Technique: Convenient sampling technique will be used for selection of patient after that simple random sampling technique will be used for randomization among groups Study Setting: Hospital Setting SF-12, 6-min walk test, VO2 max, step test This study will not harm any fundamental rights of the patients and will consider and respect the preferences of patients.

調査の概要

状態

募集

条件

介入・治療

詳細な説明

Coronary artery bypass grafting (CABG) is a common surgical procedure for coronary artery disease (CAD). Post-CABG patients often experience decreased functional capacity, muscle strength, and quality of life due to prolonged bed rest, surgical trauma, and underlying cardiovascular disease. Cardiac Rehabilitation after coronary artery bypass graft surgery is necessary to prevent complications, improve functioning, and alleviate symptoms. Aerobic exercises and strength training are used in CR, but their combined effects on post-CABG patients are not well understood. The objective of this study will be to investigate the combined effects of aerobic exercise and strength training on functional capacity, cardiorespiratory fitness and quality of life with cardiac rehabilitation phase II among post CABG patients.

Study design will be randomized controlled trial. 42 patients will be included in study. Data will be collected from Imran Idrees hospital, Sialkot. Convenient sampling technique will be used for selection of patient after that simple random sampling technique for randomization among groups. Study will be conducted within 10 months after approval of synopsis. The SF-12 questionnaire will be used for quality of life, 6-minute walk test for functional capacity, step test and VO2max for cardiorespiratory fitness. Both genders aged between 30 to 60 years with stable cardiovascular condition and no other comorbidities will be included in this study. Participants with any musculoskeletal or neurological impairment and symptoms of significant myocardial ischemia, including chest pain and any history of fracture or surgery will be excluded from this study. Patients will be divided in to two groups. Group A will be assigned aerobic exercise and Group B will be assigned aerobic exercise and strength training. Pre and post values for functional capacity, cardiorespiratory fitness and quality of life will be recorded. Data will be analyzed by using SPSS version 24. After testing the Normality of data by applying Shapiro-wilk test, paired sample t-test/ independent t-test / Anova test to find which technique will be more beneficial for post CABG patients.

研究の種類

介入

入学 (推定)

42

段階

  • 適用できない

連絡先と場所

このセクションには、調査を実施する担当者の連絡先の詳細と、この調査が実施されている場所に関する情報が記載されています。

研究連絡先

研究連絡先のバックアップ

研究場所

  • パキスタン
    • Punjab Province
      • Sialkot、Punjab Province、パキスタン、40100
        • 募集
        • Imran Idrees teaching hospital sialkot
        • コンタクト：
        • 主任研究者：
          • Nida Khalid, MS PT

参加基準

研究者は、適格基準と呼ばれる特定の説明に適合する人を探します。これらの基準のいくつかの例は、人の一般的な健康状態または以前の治療です。

適格基準

就学可能な年齢

  • 大人

健康ボランティアの受け入れ

いいえ

説明

Inclusion Criteria:

  • Both genders (male, female)

    • Patient who underwent a successful CABG (no complications during surgery and/or in the following weeks)
    • Patients willing to participate in the phase II cardiac rehabilitation program.
    • Age between 30 to 60 years
    • Patients having no impairment in the musculoskeletal system

Exclusion Criteria:

  • Patients with unstable congestive heart failure and symptoms of significant myocardial ischemia, including chest pain

    • Patients with uncontrolled diabetes mellitus or hypertension.
    • Patients with any motor or neurological impairment
    • Patients with severe disturbance of consciousness, having an orthopedic problem and critical limb ischemia

研究計画

このセクションでは、研究がどのように設計され、研究が何を測定しているかなど、研究計画の詳細を提供します。

研究はどのように設計されていますか？

デザインの詳細

  • 主な目的：処理
  • 割り当て：ランダム化
  • 介入モデル：並列代入
  • マスキング：ダブル

武器と介入

参加者グループ / アーム
介入・治療
アクティブコンパレータ：aerobic exercise
Aerobic exercise refers to the type of repetitive, structured physical activity that requires the body's metabolic system to use oxygen to produce energy. Aerobic exercise improves the capacity of the cardiovascular system to uptake and transport oxygen. Aerobic exercise training intensity is the most important variable in improving CRF during CR for most patients. Upper limb cycle ergometry is a form of aerobic exercise that can be tailored to individual needs. In the described protocol, patients perform 5 minutes of active exercise followed by 2 minutes of recovery, maintaining 20-30 rotations per minute. Moderate-intensity continuous aerobic training (MCT) is defined as 60% to 85% of peak heart rate and/or RPE of 12 to 14 on the 6 to 20 scale.
行動：aerobic exercise

Aerobic Exercise Plan:

  1. Warm-up (5 minutes): - Light arm movements (e.g., arm circles, shoulder rolls) - Dynamic stretching (e.g., arm swings)
  2. Aerobic Exercise (20-30 minutes): - Arm cycle ergometer - Intensity: Moderate (40-60% of maximum heart rate reserve) - Frequency: 2-3 times per week
  3. Cool-down (5-10 minutes): - Static stretching (e.g., bicep, triceps, chest muscles)
アクティブコンパレータ：Aerobic Exercise and strength training
supervised exercise sessions 3 times per week for 6 months. Thus, in addition to the aerobic exercise training (as above), upper extremity resistance exercise was initially prescribed at 30% of 1RM, increasing to a maximum of 70% of 1RM by 4 weeks. Seventy percent of 1RM is in the comfortably hard range (5-7 on the Borg 1-10 scale, which is comparable to 13-15 on the 6-20 Borg scale). Each exercise repetition involved a slow controlled movement with approximately 2 sec of concentric lifting and 4 sec of eccentric lowering. Proper breathing techniques were enforced (with expiration during concentric lifting and inspiration during eccentric lowering).
行動：Aerobic Exercise and strength training
  1. Warm-up (5-10 minutes): - Light cardio (e.g., walking, jogging in place) - Dynamic stretching (e.g., arm circles, leg swings)
  2. Aerobic Exercise (10-20 minutes): - Arm cycle ergometer - Intensity: Moderate (40-60% of maximum heart rate reserve) - Frequency: 2-3 times per week
  3. Resistance Training (10-15 minutes): - Upper extremity exercises using resistance bands or light dumbbells - 2-3 sets of 8-12 repetitions per exercise - Intensity: 30-70% of 1RM - Frequency: 2-3 times per week

Cool-down (5-10 minutes): - Static stretching (e.g., bicep, triceps, chest muscles)

この研究は何を測定していますか？

主要な結果の測定

結果測定
メジャーの説明
時間枠
Six-Minute Walk Test (6MWT)
時間枠：5 weeks
The six-minute walk test (6MWT) is a simple test that objectively evaluates a patient's functional capacity. This simple walk test is particularly applicable in the CAD population due to the risk of acute cardiac events associated with the gold standard maximal exercise testing for assessing functional capacity. The 6MWT requires a 30-m, flat, hard walking path, a stopwatch, a lap counter and two cones to mark the turning points. The patients were instructed to walk as far as possible along the pathway, in 6 minutes. During the test encouragement was not given and only asked about their conditions. At the end, total walked distance was measured and recorded
5 weeks
Step test
時間枠：5 weeks
The 6 min step test is a safe, valid, sensitive, and reproducible tool for evaluating cardiorespiratory fitness. The 6MST was shown to be a safe and reliable field test to assess exercise tolerance in a sample of very deconditioned adults at risk of CVD
5 weeks
Vo2 max
時間枠：5 weeks
Vo2 max was estimated using a graded exercise test. Oxygen consumption was measured using metabolic gas analyzer. In this research VO2 Max will be measured through a submaximal 6 mint walk test
5 weeks

二次結果の測定

結果測定
メジャーの説明
時間枠
SF-12 Questionnaire
時間枠：5 weeks
The SF-12 are multi-item generic health surveys intended to measure general health. The SF 12 is a shorter version of the SF-36 and uses only 12 questions to measure functional health and well-being from the patient's perspective. SF-12 were first published in 1992 and 1996, respectively, with the revised versions of both questionnaires published in 2000. SF-12 measure 8 health domains: physical functioning, role physical, bodily pain, general health, vitality, social functioning, role emotional, and mental health. The SF-12 consists of 12 items: 2 items on physical functioning, 2 items on role physical, 1 item on bodily pain, 1 item on general health, 1 item on vitality, 1 item on social functioning, 2 items on role emotional, and 2 items on mental health.
5 weeks

協力者と研究者

ここでは、この調査に関係する人々や組織を見つけることができます。

スポンサー

Riphah International University

捜査官

  • 主任研究者：Arjumand Bano, MS、Riphah International University

研究記録日

これらの日付は、ClinicalTrials.gov への研究記録と要約結果の提出の進捗状況を追跡します。研究記録と報告された結果は、国立医学図書館 (NLM) によって審査され、公開 Web サイトに掲載される前に、特定の品質管理基準を満たしていることが確認されます。

主要日程の研究

研究開始 (実際)

2026年6月1日

一次修了 (推定)

2026年8月1日

研究の完了 (推定)

2026年8月1日

試験登録日

最初に提出

2026年6月1日

QC基準を満たした最初の提出物

2026年7月17日

最初の投稿 (実際)

2026年7月20日

学習記録の更新

投稿された最後の更新 (実際)

2026年7月20日

QC基準を満たした最後の更新が送信されました

2026年7月17日

最終確認日

2026年7月1日

詳しくは

本研究に関する用語

キーワード

追加の関連 MeSH 用語

その他の研究ID番号

  • REC/RCR & AHS/25/0301

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