Impact of Stroke Unit Care on Acute Stroke Outcomes
2026年8月5日 更新者：Rania Hussein Ibrahim Mohammed、Assiut University
Impact of Stroke Unit Care on Outcome of Acute Stroke Patients
This observational study is designed to evaluate and compare the recovery outcomes of patients who have experienced their first acute stroke. Specifically, it looks at how receiving care in a specialized Stroke Unit compares to receiving care in a conventional hospital neurology ward.
Researchers will observe 140 adult patients admitted to Assiut University Hospital within 48 hours of their stroke symptoms starting. Patients will be observed in two distinct groups of 70 based on their admission setting:
- Stroke Unit Care: Patients in this group receive care from a specialized, multi-professional team (including vascular neurologists, stroke nurses, neuro-physiotherapists, and clinical pharmacists). They undergo continuous heart and vital sign monitoring for the first 24 to 48 hours, participate in early physical activity protocols, and follow strict guidelines for swallowing checks, temperature control, and blood sugar management.
- Conventional Ward Care: Patients in this group receive standard medical care and general nursing management. Their vital signs are checked during routine shifts, and physical therapy is provided only when specifically requested on a case-by-case basis.
The study will track the patients' progress by measuring their independence in daily activities, physical disability levels, and cognitive (thinking) skills. Assessments will happen when they are discharged from the hospital, and then again at 2 weeks, 1 month, 2 months, and 3 months after they go home to evaluate their overall recovery, complications, and mortality rates.
調査の概要
研究の種類
観察的
入学 (推定)
140
参加基準
研究者は、適格基準と呼ばれる特定の説明に適合する人を探します。これらの基準のいくつかの例は、人の一般的な健康状態または以前の治療です。
適格基準
就学可能な年齢
- 大人
- 高齢者
健康ボランティアの受け入れ
なし
サンプリング方法
非確率サンプル
調査対象母集団
The study population consists of adult patients (aged 18 years and older) who present with an acute, first-ever stroke (either ischemic or hemorrhagic).
Patients must be admitted to the hospital within 48 hours of their initial symptom onset.
The population will be recruited from admissions to either the general Neurology inpatient wards or the specialized Stroke Unit within the Neurology and Psychiatry, and Neurosurgery departments at Assiut University Hospital over a 6-month duration.
説明
Inclusion Criteria:
- Patients aged ≥ 18 years at the time of presentation.
- Confirmed clinical diagnosis of acute first ever stroke (either ischemic or hemorrhagic) supported by objective neuroimaging findings via history case taking and emergency CT or MRI scans.
- Hospital admission initiated within 48 hours of initial symptom onset.
- Informed consent provided, signed, and dated by the patient or a legally authorized proxy representative.
Exclusion Criteria:
- Diagnosis of a Transient Ischemic Attack (TIA) or presenting stroke mimics (e.g., complex migraines, severe hypoglycemia, conversion disorders, status epilepticus).
- Pre-existing severe functional disability prior to the index stroke event, established as a baseline pre-stroke Modified Rankin Scale (mRS) score > 2.
- Co-morbid advanced or terminal medical or neurological or psychiatric conditions with a documented clinical life expectancy of less than 6 months.
- Incomplete medical charts, structural data gaps, or formal withdrawal on baseline assessment or on hospital stay assessment before discharge.
研究計画
このセクションでは、研究がどのように設計され、研究が何を測定しているかなど、研究計画の詳細を提供します。
研究はどのように設計されていますか？
デザインの詳細
コホートと介入
グループ/コホート |
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Dedicated Stroke Unit (SU) Care
Patients admitted to the stroke unit for acute stroke management.
Core interventions include care managed by a specialized multi-professional team consisting of vascular neurologists, specialized stroke nurses, neuro-physiotherapists, and clinical pharmacists.
Care also involves continuous non-invasive cardiac, telemetry, and hemodynamic tracking for at least the initial 24-48 hours, evidence-based early mobilization protocols, and standardized integrated clinical pathways focusing on early dysphagia screening, rapid glycemic control, and strict normothermia management.
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Conventional Ward Care
Patients confirmed to have an acute stroke who are admitted directly to neurology wards for acute stroke management.
Care components include standard medical workup, generalized nursing management, and intermittent monitoring of vital signs dictated by routine ward shift protocols.
On-call or scheduled consultations from physical therapy are requested on an ad-hoc, case-by-case basis.
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この研究は何を測定していますか？
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
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Degree of Functional Dependence Using the Barthel Index
時間枠：Baseline (on admission)
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The Barthel Index measures a patient's degree of independence in daily activity performance.
Possible scores range from 0 to 100, with higher scores indicating a higher degree of independence (better outcome)
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Baseline (on admission)
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Degree of Functional Dependence Using the Barthel Index
時間枠：2 weeks post-discharge
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The Barthel Index measures a patient's degree of independence in daily activity performance.
Possible scores range from 0 to 100, with higher scores indicating a higher degree of independence (better outcome)
|
2 weeks post-discharge
|
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Degree of Functional Dependence Using the Barthel Index
時間枠：1 month post-discharge
|
The Barthel Index measures a patient's degree of independence in daily activity performance.
Possible scores range from 0 to 100, with higher scores indicating a higher degree of independence (better outcome)
|
1 month post-discharge
|
|
Degree of Functional Dependence Using the Barthel Index
時間枠：2 month post-discharge
|
The Barthel Index measures a patient's degree of independence in daily activity performance.
Possible scores range from 0 to 100, with higher scores indicating a higher degree of independence (better outcome)
|
2 month post-discharge
|
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Degree of Functional Dependence Using the Barthel Index
時間枠：3 month post-discharge
|
The Barthel Index measures a patient's degree of independence in daily activity performance.
Possible scores range from 0 to 100, with higher scores indicating a higher degree of independence (better outcome)
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3 month post-discharge
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協力者と研究者
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スポンサー
研究記録日
これらの日付は、ClinicalTrials.gov への研究記録と要約結果の提出の進捗状況を追跡します。研究記録と報告された結果は、国立医学図書館 (NLM) によって審査され、公開 Web サイトに掲載される前に、特定の品質管理基準を満たしていることが確認されます。
主要日程の研究
研究開始 (推定)
2026年9月1日
一次修了 (推定)
2027年9月1日
研究の完了 (推定)
2027年10月1日
試験登録日
最初に提出
2026年8月1日
QC基準を満たした最初の提出物
2026年8月5日
最初の投稿 (実際)
2026年8月6日
学習記録の更新
投稿された最後の更新 (実際)
2026年8月6日
QC基準を満たした最後の更新が送信されました
2026年8月5日
最終確認日
2026年8月1日
詳しくは
本研究に関する用語
その他の研究ID番号
- Acute Stroke Unit Outcomes
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