Diabetes Study With Rosiglitazone Monotherapy Versus Metformin Or Glyburide/Glibenclamide
2017년 11월 27일 업데이트: GlaxoSmithKline
A Randomized, Double-Blind Study to Compare the Durability of Glucose Lowering and Preservation of Pancreatic Beta-Cell Function of Rosiglitazone Monotherapy Compared to Metformin or Glyburide/Glibenclamide in Patients With Drug-Naive, Recently Diagnosed Type 2 Diabetes Mellitus
The study will compare and evaluate the effects of long-term treatment of monotherapy with rosiglitazone, metformin and glyburide/glibenclamide on the improvement and maintenance of glycemic control in patients with recently diagnosed type 2 diabetes mellitus.
연구 개요
연구 유형
중재적
등록 (실제)
4426
단계
- 3단계
연락처 및 위치
이 섹션에서는 연구를 수행하는 사람들의 연락처 정보와 이 연구가 수행되는 장소에 대한 정보를 제공합니다.
연구 장소
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De Bilt, 네덜란드, 3731 DN
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Den Bosch, 네덜란드, 5223 GV
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Geleen, 네덜란드, 6166 GR
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Hengelo, 네덜란드, 7555 DL
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Huizen, 네덜란드, 1271 BB
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Losser, 네덜란드, 7581 BV
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Losser, 네덜란드, 7582 BD
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Rijswijk, 네덜란드, 2281 AK
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Roelofarendsveen, 네덜란드, 2371 RB
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Woerden, 네덜란드, 3443 GG
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Hamar, 노르웨이, 2317
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Paradis, 노르웨이, 5231
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Skedsmokorset, 노르웨이, N-2020
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Frederiksberg C, 덴마크, 1900
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Odense, 덴마크, 5000
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Berlin, 독일, 13355
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Berlin, 독일, 13057
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Hamburg, 독일, 22041
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Hamburg, 독일, 22607
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Baden-Wuerttemberg
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Bad Rappenau, Baden-Wuerttemberg, 독일, 74906
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Deggingen, Baden-Wuerttemberg, 독일, 73326
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Mannheim, Baden-Wuerttemberg, 독일, 68161
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Trochtelfingen, Baden-Wuerttemberg, 독일, 72818
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Unterschneidheim, Baden-Wuerttemberg, 독일, 73485
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Wangen, Baden-Wuerttemberg, 독일, 88239
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Weinheim, Baden-Wuerttemberg, 독일, 69469
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Bayern
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Aschaffenburg, Bayern, 독일, 63739
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Haag, Bayern, 독일, 83527
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Hoehenkirchen-Siegertsbrunn, Bayern, 독일, 85635
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Ismaning, Bayern, 독일, 85737
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Krummenaab, Bayern, 독일, 92703
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Kuenzing, Bayern, 독일, 94550
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Landshut, Bayern, 독일, 84028
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Muenchen, Bayern, 독일, 80339
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Muenchen, Bayern, 독일, 80805
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Muenchen, Bayern, 독일, 80469
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Muenchen, Bayern, 독일, 80807
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Muenchen, Bayern, 독일, 80937
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Muenchen, Bayern, 독일, 81379
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Nuernberg, Bayern, 독일, 90427
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Wallerfing, Bayern, 독일, 94574
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Hessen
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Bad Kreuznach, Hessen, 독일, 55545
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Frankfurt, Hessen, 독일, 60326
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Grossalmerode, Hessen, 독일, 37247
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Lollar, Hessen, 독일, 35475
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Offenbach, Hessen, 독일, 63071
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Offenbach, Hessen, 독일, 63067
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Offenbach, Hessen, 독일, 63065
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Offenbach, Hessen, 독일, 63073
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Schaafheim, Hessen, 독일, 64850
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Vellmar, Hessen, 독일, 34246
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Niedersachsen
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Damme, Niedersachsen, 독일, 49401
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Hannover, Niedersachsen, 독일, 30171
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Hannover, Niedersachsen, 독일, 30177
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Hildesheim, Niedersachsen, 독일, 31139
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Lueneburg, Niedersachsen, 독일, 21335
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Paderborn, Niedersachsen, 독일, 33100
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Winsen/Lohe, Niedersachsen, 독일, 21423
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Nordrhein-Westfalen
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Beckum, Nordrhein-Westfalen, 독일, 59269
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Bergkamen, Nordrhein-Westfalen, 독일, 59192
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Borken, Nordrhein-Westfalen, 독일, 46325
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Dortmund, Nordrhein-Westfalen, 독일, 44137
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Duisburg, Nordrhein-Westfalen, 독일, 47119
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Essen, Nordrhein-Westfalen, 독일, 45130
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Euskirchen, Nordrhein-Westfalen, 독일, 53879
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Goch, Nordrhein-Westfalen, 독일, 47574
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Luedenscheid, Nordrhein-Westfalen, 독일, 58511
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Luenen, Nordrhein-Westfalen, 독일, 44534
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Neuss, Nordrhein-Westfalen, 독일, 41460
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Schwabenheim, Nordrhein-Westfalen, 독일, 55270
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Siegen, Nordrhein-Westfalen, 독일, 57072
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Warendorf, Nordrhein-Westfalen, 독일, 48231
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Rheinland-Pfalz
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Deidesheim, Rheinland-Pfalz, 독일, 67146
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Diez, Rheinland-Pfalz, 독일, 65582
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Lambrecht, Rheinland-Pfalz, 독일, 67466
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Rhaunen, Rheinland-Pfalz, 독일, 55624
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Sachsen
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Chemnitz, Sachsen, 독일, 09130
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Dresden, Sachsen, 독일, 01309
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Dresden, Sachsen, 독일, 01129
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Dresden, Sachsen, 독일, 01187
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Freital, Sachsen, 독일, 01705
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Pirna, Sachsen, 독일, 01796
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Schmiedeberg, Sachsen, 독일, 01762
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Schleswig-Holstein
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Itzehoe, Schleswig-Holstein, 독일, 25524
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Ratzeburg, Schleswig-Holstein, 독일, 23909
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Wahlstedt, Schleswig-Holstein, 독일, 23812
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Wilster, Schleswig-Holstein, 독일, 25554
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Alabama
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Anniston, Alabama, 미국, 36207
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Birmingham, Alabama, 미국, 35233
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Arizona
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Mesa, Arizona, 미국, 85206
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Tucson, Arizona, 미국, 85723
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Arkansas
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Little Rock, Arkansas, 미국, 77205
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California
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Berkeley, California, 미국, 94705
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Corona, California, 미국, 92879
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Fair Oaks, California, 미국, 95628
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Fremont, California, 미국, 94538
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Fresno, California, 미국, 93720
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Fullerton, California, 미국, 92835
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Greenbrae, California, 미국, 94904
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Harbor City, California, 미국, 90710
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Healdsburg, California, 미국, 95448
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La Jolla, California, 미국, 92037
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Loma Linda, California, 미국, 92354
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Los Angeles, California, 미국, 90095
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Los Angeles, California, 미국, 90059
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Modesto, California, 미국, 95355
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Pasadena, California, 미국, 91105
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San Diego, California, 미국, 92126
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San Francisco, California, 미국, 94143
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Santa Rosa, California, 미국, 95405
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Sunnyvale, California, 미국, 94086
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Ukiah, California, 미국, 95482
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Walnut Creek, California, 미국, 94598
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Yorba Linda, California, 미국, 92886
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Colorado
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Boulder, Colorado, 미국, 80304
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Denver, Colorado, 미국, 80209
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Denver, Colorado, 미국, 80220
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Englewood, Colorado, 미국, 80110
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Longmont, Colorado, 미국, 80501
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Wheat Ridge, Colorado, 미국, 80033
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Wheat Ridge, Colorado, 미국, 80043
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District of Columbia
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Washington, District of Columbia, 미국, 20037
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Washington, District of Columbia, 미국, 20003
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Florida
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Fort Myers, Florida, 미국, 33907
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Hollywood, Florida, 미국, 33023
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Jacksonville, Florida, 미국, 32216
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Jacksonville, Florida, 미국, 32204
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Melbourne, Florida, 미국, 32935
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Miami, Florida, 미국, 33136
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Miami, Florida, 미국, 33176
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Orlando, Florida, 미국, 32806
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Palm Harbor, Florida, 미국, 34683
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Saint Petersburg, Florida, 미국, 33710
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Saint Petersburg, Florida, 미국, 33702
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Sarasota, Florida, 미국, 34239
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Tampa, Florida, 미국, 33612
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Titusville, Florida, 미국, 32796
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West Palm Beach, Florida, 미국, 33401
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Georgia
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Atlanta, Georgia, 미국, 30322
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Atlanta, Georgia, 미국, 30312
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Atlanta, Georgia, 미국, 30308
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Atlanta, Georgia, 미국, 30338
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Atlanta, Georgia, 미국, 30328
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Blue Ridge, Georgia, 미국, 30513
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Dunwoody, Georgia, 미국, 30338
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Fayetteville, Georgia, 미국, 30214
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Hawaii
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Honolulu, Hawaii, 미국, 96813
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Idaho
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Boise, Idaho, 미국, 83706
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Illinois
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Chicago, Illinois, 미국, 60612
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Gurnee, Illinois, 미국, 60031
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Springfield, Illinois, 미국, 62704
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Indiana
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Evansville, Indiana, 미국, 47713
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Indianapolis, Indiana, 미국, 46202
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Indianapolis, Indiana, 미국, 46250
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Kentucky
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Lexington, Kentucky, 미국, 40504-2681
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Louisiana
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Lake Charles, Louisiana, 미국, 70601
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New Orleans, Louisiana, 미국, 70119
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Slidell, Louisiana, 미국, 70461
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Slidell, Louisiana, 미국, 70458
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Maine
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Bangor, Maine, 미국, 04401
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Maryland
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Baltimore, Maryland, 미국, 21201
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Baltimore, Maryland, 미국, 21208
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Baltimore, Maryland, 미국, 21204
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Baltimore, Maryland, 미국, 21205
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Massachusetts
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Boston, Massachusetts, 미국, 02114
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Springfield, Massachusetts, 미국, 01199
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Michigan
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Ann Arbor, Michigan, 미국, 48109
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Detroit, Michigan, 미국, 48201
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Lansing, Michigan, 미국, 48912
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Royal Oak, Michigan, 미국, 48073
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Minnesota
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Minneapolis, Minnesota, 미국, 55404
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Minneapolis, Minnesota, 미국, 55407-3799
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Minneapolis, Minnesota, 미국, 55416
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Mississippi
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Jackson, Mississippi, 미국, 39202
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Olive Branch, Mississippi, 미국, 38654
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Missouri
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Kansas City, Missouri, 미국, 64132
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Saint Louis, Missouri, 미국, 63110
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Saint Louis, Missouri, 미국, 63128
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Montana
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Billings, Montana, 미국, 59102
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Nebraska
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Omaha, Nebraska, 미국, 68131
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Omaha, Nebraska, 미국, 68105
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Nevada
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Henderson, Nevada, 미국, 89014
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New Jersey
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Cherry Hill, New Jersey, 미국, 08034
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Cherry Hill, New Jersey, 미국, 8034
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New Mexico
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Albuquerque, New Mexico, 미국, 87106
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Albuquerque, New Mexico, 미국, 87102
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Albuquerque, New Mexico, 미국, 87109
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New York
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Albany, New York, 미국, 12206
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Bronx, New York, 미국, 10461
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Endwell, New York, 미국, 13760
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Flushing, New York, 미국, 11365
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New York, New York, 미국, 10032
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New York, New York, 미국, 10021
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New York, New York, 미국, 10029
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New York, New York, 미국, 10003
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New York, New York, 미국, 10010
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Rochester, New York, 미국, 14642
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Rochester, New York, 미국, 14609
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Syracuse, New York, 미국, 13210
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North Carolina
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Durham, North Carolina, 미국, 27710
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Ohio
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Cincinnati, Ohio, 미국, 45219
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Cleveland, Ohio, 미국, 44195
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Cleveland, Ohio, 미국, 44121
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Mogadore, Ohio, 미국, 44260
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Westlake, Ohio, 미국, 44145
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Oklahoma
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Oklahoma City, Oklahoma, 미국, 73104
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Oregon
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Bend, Oregon, 미국, 97701
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Eugene, Oregon, 미국, 97401
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Portland, Oregon, 미국, 97239
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Portland, Oregon, 미국, 97219
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Pennsylvania
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Downingtown, Pennsylvania, 미국, 19335
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Feasterville, Pennsylvania, 미국, 19053
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Fleetwood, Pennsylvania, 미국, 19522
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Hermitage, Pennsylvania, 미국, 16148
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Hershey, Pennsylvania, 미국, 17033
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Jefferson Hills, Pennsylvania, 미국, 15025
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Philadelphia, Pennsylvania, 미국, 19107
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Philadelphia, Pennsylvania, 미국, 19104
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Philadelphia, Pennsylvania, 미국, 19115
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Philadelphia, Pennsylvania, 미국, 19148
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Pittsburgh, Pennsylvania, 미국, 15219
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Upland, Pennsylvania, 미국, 19013
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Warminster, Pennsylvania, 미국, 18974
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West Chester, Pennsylvania, 미국, 19380
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South Carolina
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Charleston, South Carolina, 미국, 29403
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Columbia, South Carolina, 미국, 29201
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Greer, South Carolina, 미국, 29651
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Spartanburg, South Carolina, 미국, 29303
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Tennessee
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Bristol, Tennessee, 미국, 37620
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Nashville, Tennessee, 미국, 37211
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Texas
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Arlington, Texas, 미국, 76014
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Austin, Texas, 미국, 78745
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Beaumont, Texas, 미국, 77701
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Corpus Christi, Texas, 미국, 78412
- GSK Investigational Site
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Corpus Christi, Texas, 미국, 78411
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Dallas, Texas, 미국, 75230
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Dallas, Texas, 미국, 75231
- GSK Investigational Site
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Dallas, Texas, 미국, 75390
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Fort Worth, Texas, 미국, 76107
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Houston, Texas, 미국, 77030
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Houston, Texas, 미국, 77024
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Irving, Texas, 미국, 75061
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Midland, Texas, 미국, 79705
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San Antonio, Texas, 미국, 78229
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San Antonio, Texas, 미국, 78207
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Utah
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Ogden, Utah, 미국, 84403
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Salt Lake City, Utah, 미국, 84103
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Salt Lake City, Utah, 미국, 84108
- GSK Investigational Site
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Virginia
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Charlottesville, Virginia, 미국, 22908
- GSK Investigational Site
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Newport News, Virginia, 미국, 23606
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Richmond, Virginia, 미국, 23249
- GSK Investigational Site
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Salem, Virginia, 미국, 24153
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Washington
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Federal Way, Washington, 미국, 98003
- GSK Investigational Site
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Seattle, Washington, 미국, 98195
- GSK Investigational Site
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Seattle, Washington, 미국, 98108
- GSK Investigational Site
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Seattle, Washington, 미국, 98104
- GSK Investigational Site
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Spokane, Washington, 미국, 99204
- GSK Investigational Site
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Spokane, Washington, 미국, 99208
- GSK Investigational Site
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Spokane, Washington, 미국, 99207
- GSK Investigational Site
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Wenatchee, Washington, 미국, 98801
- GSK Investigational Site
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West Virginia
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Charleston, West Virginia, 미국, 25304
- GSK Investigational Site
-
Huntington, West Virginia, 미국, 25701
- GSK Investigational Site
-
-
Wisconsin
-
Madison, Wisconsin, 미국, 53717
- GSK Investigational Site
-
Milwaukee, Wisconsin, 미국, 53209
- GSK Investigational Site
-
Oregon, Wisconsin, 미국, 53575
- GSK Investigational Site
-
-
-
-
-
Blankenberge, 벨기에, 8370
- GSK Investigational Site
-
Boechout, 벨기에, 2530
- GSK Investigational Site
-
Deurne, 벨기에, 2100
- GSK Investigational Site
-
Leuven, 벨기에, 3000
- GSK Investigational Site
-
Lubbeek (Linden), 벨기에, B-3210
- GSK Investigational Site
-
Tielt, 벨기에, 8700
- GSK Investigational Site
-
Wezembeek-Oppem, 벨기에, 1970
- GSK Investigational Site
-
Wijnegem, 벨기에, 2110
- GSK Investigational Site
-
Zemst, 벨기에, 1980
- GSK Investigational Site
-
-
-
-
-
Alta, 스웨덴, 138 21
- GSK Investigational Site
-
Degerberga, 스웨덴, 297 31
- GSK Investigational Site
-
Gimo, 스웨덴, SE-747 43
- GSK Investigational Site
-
Malmö, 스웨덴, SE-214 26
- GSK Investigational Site
-
Stockholm, 스웨덴, SE-114 35
- GSK Investigational Site
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-
-
-
-
Albaida (Valencia), 스페인
- GSK Investigational Site
-
Basurto/Bilbao, 스페인, 48013
- GSK Investigational Site
-
Benassal (Castellón), 스페인, 12160
- GSK Investigational Site
-
Benicasim (Castellón), 스페인
- GSK Investigational Site
-
Bilbao, 스페인, 48013
- GSK Investigational Site
-
Cartagena, 스페인, 30203
- GSK Investigational Site
-
Cáceres, 스페인, 10005
- GSK Investigational Site
-
El Palmar (Murcia), 스페인, 30120
- GSK Investigational Site
-
Elche (Alicante), 스페인, 03202
- GSK Investigational Site
-
Elda-Alicante, 스페인, 03600
- GSK Investigational Site
-
Figueras, 스페인, 17600
- GSK Investigational Site
-
Gerona, 스페인
- GSK Investigational Site
-
Granollers (Barcelona), 스페인, 08400
- GSK Investigational Site
-
Jerez (Cadiz), 스페인, 11047
- GSK Investigational Site
-
Madrid, 스페인, 28006
- GSK Investigational Site
-
Madrid, 스페인, 28046
- GSK Investigational Site
-
Malaga, 스페인, 29009
- GSK Investigational Site
-
Mataro, 스페인, 08034
- GSK Investigational Site
-
Merida, 스페인, 6800
- GSK Investigational Site
-
Olleria, Valencia, 스페인, 46850
- GSK Investigational Site
-
Onda/Castellón, 스페인, 12200
- GSK Investigational Site
-
Orihuela (Alicante), 스페인, 03314
- GSK Investigational Site
-
Plasencia, 스페인, 10600
- GSK Investigational Site
-
Pontevedra, 스페인, 36071
- GSK Investigational Site
-
Sagunto/Valencia, 스페인, 46520
- GSK Investigational Site
-
San Juan (Alicante), 스페인, 03550
- GSK Investigational Site
-
San Vincente Raspeig (Alicante), 스페인, 03690
- GSK Investigational Site
-
Santa Coloma De Gramanet (Barcelona), 스페인, 08923
- GSK Investigational Site
-
Tenerife, 스페인, 38010
- GSK Investigational Site
-
Tereul, 스페인, 44002
- GSK Investigational Site
-
Toledo, 스페인, 45004
- GSK Investigational Site
-
Torrelavega/Santander, 스페인, 39300
- GSK Investigational Site
-
Valencia, 스페인, 46017
- GSK Investigational Site
-
Valencia, 스페인
- GSK Investigational Site
-
Valencia, 스페인, 46830
- GSK Investigational Site
-
Valladolid, 스페인, 47010
- GSK Investigational Site
-
Vallda (Valencia), 스페인
- GSK Investigational Site
-
Villajoyosa - Alicante, 스페인, 03570
- GSK Investigational Site
-
Zamora, 스페인, 49021
- GSK Investigational Site
-
Zaragoza, 스페인, 50003
- GSK Investigational Site
-
-
-
-
-
Belfast, 아일랜드, BT16 ORH
- GSK Investigational Site
-
Co. Tipperary, 아일랜드
- GSK Investigational Site
-
Cork, 아일랜드
- GSK Investigational Site
-
Dublin, 아일랜드, 8
- GSK Investigational Site
-
Dublin, 아일랜드, 4
- GSK Investigational Site
-
Dublin, 아일랜드, 7
- GSK Investigational Site
-
Dublin, 아일랜드, 15
- GSK Investigational Site
-
Dublin, 아일랜드, 24
- GSK Investigational Site
-
Gowran, 아일랜드
- GSK Investigational Site
-
Kilkenny, 아일랜드
- GSK Investigational Site
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-
-
-
-
Barnsley, 영국, S70 3RJ
- GSK Investigational Site
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Bath, 영국, BA2 3HT
- GSK Investigational Site
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Bradford, 영국, BD7 3EE
- GSK Investigational Site
-
Cardiff, 영국, CF5 4AE
- GSK Investigational Site
-
Co.Antrim, 영국
- GSK Investigational Site
-
Doncaster, 영국, DN1 2EG
- GSK Investigational Site
-
Doncaster, 영국, DN9 1EP
- GSK Investigational Site
-
Gateshead, 영국, NE9 6SX
- GSK Investigational Site
-
Glasgow, 영국, G51 4TF
- GSK Investigational Site
-
Glenrothes, 영국
- GSK Investigational Site
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Irvine, 영국, KA12 OAY
- GSK Investigational Site
-
Kent, 영국, TN11 9HL
- GSK Investigational Site
-
Leicester, 영국, LE3 8GS
- GSK Investigational Site
-
London, 영국, SE1 9RT
- GSK Investigational Site
-
London, 영국, W1M 7AB
- GSK Investigational Site
-
Newtownabbey, 영국, BT36 4PP
- GSK Investigational Site
-
Peterborough, 영국, PE7 3JL
- GSK Investigational Site
-
Swansea, 영국, SA4 4BY
- GSK Investigational Site
-
Wakefield, 영국, WF1 4DG
- GSK Investigational Site
-
Wigan, 영국, WN1 1XX
- GSK Investigational Site
-
-
Aberdeenshire
-
Aberdeen, Aberdeenshire, 영국, AB25 2AY
- GSK Investigational Site
-
-
Bedfordshire
-
Sandy, Bedfordshire, 영국, SG19 3JR
- GSK Investigational Site
-
-
Berkshire
-
Reading, Berkshire, 영국, RG2 7AG
- GSK Investigational Site
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-
Carmarthenshire
-
Llanelli, Carmarthenshire, 영국, SA14 8QF
- GSK Investigational Site
-
-
Cheshire
-
Warrington, Cheshire, 영국, WA5 1QC
- GSK Investigational Site
-
-
Dorset
-
Bournemouth, Dorset, 영국, BH7 7DW
- GSK Investigational Site
-
Poole, Dorset, 영국
- GSK Investigational Site
-
-
Glamorgan
-
Barry, Glamorgan, 영국, CF63 4HP
- GSK Investigational Site
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Cardiff, Glamorgan, 영국, CF14 9BB
- GSK Investigational Site
-
-
Hertfordshire
-
Hemel Hempstead, Hertfordshire, 영국, HP2 4AD
- GSK Investigational Site
-
Stevenage, Hertfordshire, 영국
- GSK Investigational Site
-
-
Lanarkshire
-
Airdrie, Lanarkshire, 영국, ML6 0JS
- GSK Investigational Site
-
Glasgow, Lanarkshire, 영국, G81 4SA
- GSK Investigational Site
-
-
Lancashire
-
Bolton, Lancashire, 영국
- GSK Investigational Site
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Chorley, Lancashire, 영국, PR7 1NY
- GSK Investigational Site
-
-
Midlothian
-
Edinburgh, Midlothian, 영국, EH3 9YW
- GSK Investigational Site
-
-
Northamptonshire
-
Wellingborough, Northamptonshire, 영국, NN8 4RW
- GSK Investigational Site
-
-
Nottinghamshire
-
Nottingham, Nottinghamshire, 영국, NG3 7DQ
- GSK Investigational Site
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-
Pembrokeshire
-
Haverfordwest, Pembrokeshire, 영국, SA61 1RN
- GSK Investigational Site
-
-
Somerset
-
Frome, Somerset, 영국, BA11 1EZ
- GSK Investigational Site
-
-
Sussex West
-
Crawley, Sussex West, 영국, RH10 1LL
- GSK Investigational Site
-
-
Warwickshire
-
Nuneaton, Warwickshire, 영국, CV10 7DJ
- GSK Investigational Site
-
Rugby, Warwickshire, 영국, CV21 3SP
- GSK Investigational Site
-
-
West Lothian
-
Livingston, West Lothian, 영국, EH54 6PP
- GSK Investigational Site
-
-
Wiltshire
-
Melksham, Wiltshire, 영국, SN12 6UN
- GSK Investigational Site
-
Trowbridge, Wiltshire, 영국, BA14 8TG
- GSK Investigational Site
-
-
-
-
-
Vienna, 오스트리아, A-1130
- GSK Investigational Site
-
Vienna, 오스트리아, A-1080
- GSK Investigational Site
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Wiener Neustadt, 오스트리아, A-2700
- GSK Investigational Site
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-
-
-
-
Firenze, 이탈리아, 50134
- GSK Investigational Site
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La Spezia, 이탈리아, 19100
- GSK Investigational Site
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Lecce, 이탈리아, 73100
- GSK Investigational Site
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Milano, 이탈리아, 20132
- GSK Investigational Site
-
Palermo, 이탈리아, 90127
- GSK Investigational Site
-
Parma, 이탈리아, 43100
- GSK Investigational Site
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Perugia, 이탈리아, 06126
- GSK Investigational Site
-
Rovigo, 이탈리아, 45100
- GSK Investigational Site
-
S. Benedetto TR (AP), 이탈리아
- GSK Investigational Site
-
San Giovanni Rotondo FG, 이탈리아
- GSK Investigational Site
-
Sassari, 이탈리아
- GSK Investigational Site
-
Terni, 이탈리아, 05100
- GSK Investigational Site
-
Torino, 이탈리아, 10126
- GSK Investigational Site
-
Udine, 이탈리아, 33100
- GSK Investigational Site
-
Vicenza, 이탈리아, 36100
- GSK Investigational Site
-
-
Emilia-Romagna
-
Ferrara, Emilia-Romagna, 이탈리아, 44100
- GSK Investigational Site
-
Ravenna, Emilia-Romagna, 이탈리아, 48100
- GSK Investigational Site
-
Scandiano (RE), Emilia-Romagna, 이탈리아, 42019
- GSK Investigational Site
-
-
Lombardia
-
Rozzano (MI), Lombardia, 이탈리아, 20089
- GSK Investigational Site
-
-
Puglia
-
Acquaviva Delle Fonti (BA), Puglia, 이탈리아, 70021
- GSK Investigational Site
-
-
Sicilia
-
Catania, Sicilia, 이탈리아, 95100
- GSK Investigational Site
-
-
Umbria
-
Città Di Castello (PG), Umbria, 이탈리아, 06012
- GSK Investigational Site
-
-
-
-
-
Ostrava, 체코, 703 52
- GSK Investigational Site
-
Phaha 5, 체코, 150 06
- GSK Investigational Site
-
Praha 4, 체코, 142 00
- GSK Investigational Site
-
Usti Nad Labem, 체코, 401 13
- GSK Investigational Site
-
Zlin, 체코, 762 75
- GSK Investigational Site
-
-
-
-
Alberta
-
Calgary, Alberta, 캐나다, T2R 0X7
- GSK Investigational Site
-
Edmonton, Alberta, 캐나다, T6G 2C8
- GSK Investigational Site
-
Edmonton, Alberta, 캐나다, T5N 3Y6
- GSK Investigational Site
-
Red Deer, Alberta, 캐나다, T4N 6V7
- GSK Investigational Site
-
-
British Columbia
-
Coquitlam, British Columbia, 캐나다, V3K 3P4
- GSK Investigational Site
-
Vancouver, British Columbia, 캐나다, V5Z 1M9
- GSK Investigational Site
-
Victoria, British Columbia, 캐나다, V8R 6T9
- GSK Investigational Site
-
-
Manitoba
-
Winnipeg, Manitoba, 캐나다, R2H 2A6
- GSK Investigational Site
-
Winnipeg, Manitoba, 캐나다, R3E 3P4
- GSK Investigational Site
-
-
New Brunswick
-
Cambellton, New Brunswick, 캐나다, E3N 3S8
- GSK Investigational Site
-
Moncton, New Brunswick, 캐나다, E1C 6Z8
- GSK Investigational Site
-
-
Newfoundland and Labrador
-
Saint John's, Newfoundland and Labrador, 캐나다, A1B 3V6
- GSK Investigational Site
-
-
Nova Scotia
-
Antigonish, Nova Scotia, 캐나다, B2G 2C2
- GSK Investigational Site
-
Halifax, Nova Scotia, 캐나다, B3H 1V7
- GSK Investigational Site
-
-
Ontario
-
Burlington, Ontario, 캐나다, L7M 4Y1
- GSK Investigational Site
-
Kingston, Ontario, 캐나다, K7L 2V7
- GSK Investigational Site
-
London, Ontario, 캐나다, N6A 4V2
- GSK Investigational Site
-
Mississauga, Ontario, 캐나다, L5M 2N1
- GSK Investigational Site
-
Oakville, Ontario, 캐나다, L6H 3P1
- GSK Investigational Site
-
Ottawa, Ontario, 캐나다, K1H 7W9
- GSK Investigational Site
-
Sudbury, Ontario, 캐나다, P3A 1Y8
- GSK Investigational Site
-
Thornhill, Ontario, 캐나다, L4J 1V8
- GSK Investigational Site
-
Thunder Bay, Ontario, 캐나다, P7B 2Z3
- GSK Investigational Site
-
Timmins, Ontario, 캐나다, P4N 8P2
- GSK Investigational Site
-
Toronto, Ontario, 캐나다, M5C 2T2
- GSK Investigational Site
-
Windsor, Ontario, 캐나다, N8X 1K4
- GSK Investigational Site
-
-
Prince Edward Island
-
Charlottetown, Prince Edward Island, 캐나다, C1A 1L2
- GSK Investigational Site
-
-
Quebec
-
Chicoutimi, Quebec, 캐나다, G7H 5H6
- GSK Investigational Site
-
La Malbaie, Quebec, 캐나다, G5A 1W7
- GSK Investigational Site
-
Laval, Quebec, 캐나다, H7T 2P5
- GSK Investigational Site
-
Montreal, Quebec, 캐나다, H1T 2M4
- GSK Investigational Site
-
Montreal, Quebec, 캐나다, H2W 1T8
- GSK Investigational Site
-
Plessisville, Quebec, 캐나다, G6L 3J1
- GSK Investigational Site
-
Saint Marc Des Carrieres, Quebec, 캐나다, G0A 4B0
- GSK Investigational Site
-
Sainte-Foy, Quebec, 캐나다, G1V 4G5
- GSK Investigational Site
-
Sherbrooke, Quebec, 캐나다, J1H 5N4
- GSK Investigational Site
-
St-Isidore De Dorchester, Quebec, 캐나다, G0S 2S0
- GSK Investigational Site
-
-
Saskatchewan
-
Regina, Saskatchewan, 캐나다, S4P 0W5
- GSK Investigational Site
-
Saskatoon, Saskatchewan, 캐나다, S7N 0W8
- GSK Investigational Site
-
-
-
-
-
Alben, 프랑스, 73410
- GSK Investigational Site
-
Bezier, 프랑스, 34500
- GSK Investigational Site
-
Bourges, 프랑스, 18000
- GSK Investigational Site
-
Brogile, 프랑스, 27270
- GSK Investigational Site
-
Chartres, 프랑스, 28000
- GSK Investigational Site
-
Denguin, 프랑스, 64230
- GSK Investigational Site
-
Evreux, 프랑스, 27000
- GSK Investigational Site
-
Gamarde Les Bains, 프랑스, 40380
- GSK Investigational Site
-
La Rochelle, 프랑스, 17000
- GSK Investigational Site
-
Labarthe Sur Leze, 프랑스, 31860
- GSK Investigational Site
-
Le Mans, 프랑스, 72000
- GSK Investigational Site
-
Le Pian Medoc, 프랑스, 33290
- GSK Investigational Site
-
Lille, 프랑스, 59000
- GSK Investigational Site
-
Mallemort, 프랑스, 13370
- GSK Investigational Site
-
Marseille, 프랑스, 13008
- GSK Investigational Site
-
Marseille, 프랑스, 13001
- GSK Investigational Site
-
Marsillargues, 프랑스, 34590
- GSK Investigational Site
-
Marssac, 프랑스, 81150
- GSK Investigational Site
-
Mont De Marsen, 프랑스, 40000
- GSK Investigational Site
-
Montignac, 프랑스, 24290
- GSK Investigational Site
-
Moulon, 프랑스, 33420
- GSK Investigational Site
-
Murs Erigne, 프랑스, 49610
- GSK Investigational Site
-
Nantes, 프랑스, 44300
- GSK Investigational Site
-
Nantes Cedex 01, 프랑스, 44093
- GSK Investigational Site
-
Nimes, 프랑스, 30900
- GSK Investigational Site
-
Orthez, 프랑스, 64300
- GSK Investigational Site
-
Paris, 프랑스, 75015
- GSK Investigational Site
-
Rennes, 프랑스, 35200
- GSK Investigational Site
-
Roanna, 프랑스, 42300
- GSK Investigational Site
-
Saint Etienne, 프랑스, 42000
- GSK Investigational Site
-
Saint Genies Des Fontaines, 프랑스, 66740
- GSK Investigational Site
-
Sisteron, 프랑스, 04200
- GSK Investigational Site
-
St Julien Des Landes, 프랑스, 85150
- GSK Investigational Site
-
St Martin D'Heres, 프랑스, 38400
- GSK Investigational Site
-
St Pierre de Chandieu, 프랑스, 69780
- GSK Investigational Site
-
Strasbourg, 프랑스, 67000
- GSK Investigational Site
-
Tarare, 프랑스, 69170
- GSK Investigational Site
-
Vieux Conde, 프랑스, 59690
- GSK Investigational Site
-
Vourey, 프랑스, 38210
- GSK Investigational Site
-
-
-
-
-
Hanko, 핀란드, 10900
- GSK Investigational Site
-
Helsinki, 핀란드, 00150
- GSK Investigational Site
-
Jyvaskyla, 핀란드, 40100
- GSK Investigational Site
-
Lmatra, 핀란드, 55800
- GSK Investigational Site
-
Savitaipale, 핀란드, 54800
- GSK Investigational Site
-
-
-
-
-
Budapest, 헝가리, 1076
- GSK Investigational Site
-
Miskolc, 헝가리, 3526
- GSK Investigational Site
-
-
참여기준
연구원은 적격성 기준이라는 특정 설명에 맞는 사람을 찾습니다. 이러한 기준의 몇 가지 예는 개인의 일반적인 건강 상태 또는 이전 치료입니다.
자격 기준
공부할 수 있는 나이
30년 (성인, 고령자)
건강한 자원 봉사자를 받아들입니다
아니
연구 대상 성별
모두
설명
Inclusion criteria:
- Newly diagnosed patients (< 3years) with type 2 diabetes.
- Fasting plasma glucose (FPG) range of 126-240 mg/dL at Screening.
- No previous treatment with oral or parenteral glucose-lowering therapy.
Exclusion criteria:
- History of lactic acidosis.
- Anemia (<11g for males, <10 g for females).
- Unstable or severe NY Heart Association-class 3 or 4.
- Any NY Heart Association congestive heart failure.
- Patients with chronic diseases requiring periodic or intermittent treatment with oral or intravenous corticosteroids.
공부 계획
이 섹션에서는 연구 설계 방법과 연구가 측정하는 내용을 포함하여 연구 계획에 대한 세부 정보를 제공합니다.
연구는 어떻게 설계됩니까?
디자인 세부사항
- 주 목적: 치료
- 할당: 무작위
- 중재 모델: 병렬 할당
연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
|---|
|
Time from randomization to the primary action point (monotherapy failure).
|
2차 결과 측정
결과 측정 |
|---|
|
Comparison of effects of long-term treatment with Rosiglitazone, Metformin, Glyburide: - maintenance/restoration of beta-cell function: HOMA IS, progression of microalbuminuria, fibrinolytic markers (PAI-1,fibrinogen, CRP).
|
공동 작업자 및 조사자
여기에서 이 연구와 관련된 사람과 조직을 찾을 수 있습니다.
스폰서
간행물 및 유용한 링크
연구에 대한 정보 입력을 담당하는 사람이 자발적으로 이러한 간행물을 제공합니다. 이것은 연구와 관련된 모든 것에 관한 것일 수 있습니다.
일반 간행물
- Gnesin F, Thuesen ACB, Kahler LKA, Madsbad S, Hemmingsen B. Metformin monotherapy for adults with type 2 diabetes mellitus. Cochrane Database Syst Rev. 2020 Jun 5;6(6):CD012906. doi: 10.1002/14651858.CD012906.pub2.
- Viberti G, Kahn SE, Greene DA, Herman WH, Zinman B, Holman RR, Haffner SM, Levy D, Lachin JM, Berry RA, Heise MA, Jones NP, Freed MI. A diabetes outcome progression trial (ADOPT): an international multicenter study of the comparative efficacy of rosiglitazone, glyburide, and metformin in recently diagnosed type 2 diabetes. Diabetes Care. 2002 Oct;25(10):1737-43. doi: 10.2337/diacare.25.10.1737.
- Viberti G, Lachin J, Holman R, Zinman B, Haffner S, Kravitz B, Heise MA, Jones NP, O'Neill MC, Freed MI, Kahn SE, Herman WH; ADOPT Study Group. A Diabetes Outcome Progression Trial (ADOPT): baseline characteristics of Type 2 diabetic patients in North America and Europe. Diabet Med. 2006 Dec;23(12):1289-94. doi: 10.1111/j.1464-5491.2006.02022.x.
- Kahn SE, Haffner SM, Heise MA, Herman WH, Holman RR, Jones NP, Kravitz BG, Lachin JM, O'Neill MC, Zinman B, Viberti G; ADOPT Study Group. Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy. N Engl J Med. 2006 Dec 7;355(23):2427-43. doi: 10.1056/NEJMoa066224. Epub 2006 Dec 4. Erratum In: N Engl J Med. 2007 Mar 29;356(13):1387-8.
- Kahn SE, Zinman B, Haffner SM, O'Neill MC, Kravitz BG, Yu D, Freed MI, Herman WH, Holman RR, Jones NP, Lachin JM, Viberti GC; ADOPT Study Group. Obesity is a major determinant of the association of C-reactive protein levels and the metabolic syndrome in type 2 diabetes. Diabetes. 2006 Aug;55(8):2357-64. doi: 10.2337/db06-0116.
- Zinman B, Kahn SE, Haffner SM, O'Neill MC, Heise MA, Freed MI; ADOPT Study Group. Phenotypic characteristics of GAD antibody-positive recently diagnosed patients with type 2 diabetes in North America and Europe. Diabetes. 2004 Dec;53(12):3193-200. doi: 10.2337/diabetes.53.12.3193.
- Lachin JM, Viberti G, Zinman B, Haffner SM, Aftring RP, Paul G, Kravitz BG, Herman WH, Holman RR, Kahn SE; ADOPT Study Group. Renal function in type 2 diabetes with rosiglitazone, metformin, and glyburide monotherapy. Clin J Am Soc Nephrol. 2011 May;6(5):1032-40. doi: 10.2215/CJN.09291010. Epub 2011 Mar 31.
- Kahn SE, Haffner SM, Viberti G, Herman WH, Lachin JM, Kravitz BG, Yu D, Paul G, Holman RR, Zinman B; Diabetes Outcome Progression Trial (ADOPT) Study Group. Rosiglitazone decreases C-reactive protein to a greater extent relative to glyburide and metformin over 4 years despite greater weight gain: observations from a Diabetes Outcome Progression Trial (ADOPT). Diabetes Care. 2010 Jan;33(1):177-83. doi: 10.2337/dc09-1661. Epub 2009 Oct 6.
- Kahn SE, Zinman B, Lachin JM, Haffner SM, Herman WH, Holman RR, Kravitz BG, Yu D, Heise MA, Aftring RP, Viberti G; Diabetes Outcome Progression Trial (ADOPT) Study Group. Rosiglitazone-associated fractures in type 2 diabetes: an Analysis from A Diabetes Outcome Progression Trial (ADOPT). Diabetes Care. 2008 May;31(5):845-51. doi: 10.2337/dc07-2270. Epub 2008 Jan 25.
연구 기록 날짜
이 날짜는 ClinicalTrials.gov에 대한 연구 기록 및 요약 결과 제출의 진행 상황을 추적합니다. 연구 기록 및 보고된 결과는 공개 웹사이트에 게시되기 전에 특정 품질 관리 기준을 충족하는지 확인하기 위해 국립 의학 도서관(NLM)에서 검토합니다.
연구 주요 날짜
연구 시작
2000년 1월 3일
기본 완료 (실제)
2006년 6월 1일
연구 완료 (실제)
2006년 6월 19일
연구 등록 날짜
최초 제출
2006년 1월 17일
QC 기준을 충족하는 최초 제출
2006년 1월 17일
처음 게시됨 (추정)
2006년 1월 19일
연구 기록 업데이트
마지막 업데이트 게시됨 (실제)
2017년 11월 29일
QC 기준을 충족하는 마지막 업데이트 제출
2017년 11월 27일
마지막으로 확인됨
2017년 11월 1일
추가 정보
이 연구와 관련된 용어
기타 연구 ID 번호
- 49653/048
개별 참가자 데이터(IPD) 계획
개별 참가자 데이터(IPD)를 공유할 계획입니까?
예
IPD 계획 설명
Patient-level data for this study will be made available through www.clinicalstudydatarequest.com following the timelines and process described on this site.
연구 데이터/문서
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정보에 입각한 동의서
정보 식별자: 49653/048정보 댓글: For additional information about this study please refer to the GSK Clinical Study Register
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통계 분석 계획
정보 식별자: 49653/048정보 댓글: For additional information about this study please refer to the GSK Clinical Study Register
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연구 프로토콜
정보 식별자: 49653/048정보 댓글: For additional information about this study please refer to the GSK Clinical Study Register
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임상 연구 보고서
정보 식별자: 49653/048정보 댓글: For additional information about this study please refer to the GSK Clinical Study Register
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개별 참가자 데이터 세트
정보 식별자: 49653/048정보 댓글: For additional information about this study please refer to the GSK Clinical Study Register
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데이터 세트 사양
정보 식별자: 49653/048정보 댓글: For additional information about this study please refer to the GSK Clinical Study Register
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주석이 달린 사례 보고서 양식
정보 식별자: 49653/048정보 댓글: For additional information about this study please refer to the GSK Clinical Study Register
이 정보는 변경 없이 clinicaltrials.gov 웹사이트에서 직접 가져온 것입니다. 귀하의 연구 세부 정보를 변경, 제거 또는 업데이트하도록 요청하는 경우 register@clinicaltrials.gov. 문의하십시오. 변경 사항이 clinicaltrials.gov에 구현되는 즉시 저희 웹사이트에도 자동으로 업데이트됩니다. .