Acute Pain Caused by Paclitaxel in Patients With Cancer
2016년 7월 12일 업데이트: Alliance for Clinical Trials in Oncology
Paclitaxel-Associated Acute Pain Syndrome Natural History Study
RATIONALE: Gathering information over time from patients receiving paclitaxel for cancer may help doctors learn more about pain caused by paclitaxel and plan the best treatment.
PURPOSE: This clinical trial is studying acute pain caused by paclitaxel in patients with cancer.
연구 개요
상세 설명
OBJECTIVES:
- To describe the incidence and characteristics of and change in pain related to paclitaxel infusions over several courses in patients receiving paclitaxel weekly or every 2-4 weeks with or without neurotoxic chemotherapy.
- To investigate the association between paclitaxel-induced acute pain syndrome symptoms and eventual chemotherapy-induced neuropathy.
- To perform exome-sequencing analysis and identify genetic variants that predict paclitaxel- induced peripheral neuropathy.
- To identify clinical phenotypes associated with paclitaxel toxicity (i.e., acute pain syndrome and neuropathy).
- To explore whether there are any evident differences between results seen in the majority Caucasian population and the minority populations.
OUTLINE: This is a multicenter study. Patients are grouped according to paclitaxel dosing schedule (weekly vs every 2-4 weeks) and concurrent use of neurotoxic agent (yes vs no).
Blood samples are collected at baseline for correlative laboratory studies, including genetic biomarker and polymorphism studies.
연구 유형
관찰
등록 (실제)
306
연락처 및 위치
이 섹션에서는 연구를 수행하는 사람들의 연락처 정보와 이 연구가 수행되는 장소에 대한 정보를 제공합니다.
연구 장소
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Colorado
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Aurora, Colorado, 미국, 80012
- Aurora Presbyterian Hospital
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Boulder, Colorado, 미국, 80301-9019
- Boulder Community Hospital
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Colorado Springs, Colorado, 미국, 80933
- Penrose Cancer Center at Penrose Hospital
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Denver, Colorado, 미국, 80210
- Porter Adventist Hospital
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Denver, Colorado, 미국, 80220
- Rose Medical Center
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Denver, Colorado, 미국, 80218
- Presbyterian - St. Luke's Medical Center
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Denver, Colorado, 미국, 80204
- St. Anthony Central Hospital
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Denver, Colorado, 미국, 80218
- St. Joseph Hospital
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Denver, Colorado, 미국, 80224-2522
- CCOP - Colorado Cancer Research Program
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Englewood, Colorado, 미국, 80110
- Swedish Medical Center
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Grand Junction, Colorado, 미국, 81502
- St. Mary's Regional Cancer Center at St. Mary's Hospital and Medical Center
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Greeley, Colorado, 미국, 80631
- North Colorado Medical Center
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Littleton, Colorado, 미국, 80122
- Littleton Adventist Hospital
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Lone Tree, Colorado, 미국, 80124
- Sky Ridge Medical Center
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Longmont, Colorado, 미국, 80501
- Hope Cancer Care Center at Longmont United Hospital
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Loveland, Colorado, 미국, 80539
- McKee Medical Center
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Parker, Colorado, 미국, 80138
- Parker Adventist Hospital
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Pueblo, Colorado, 미국, 81004
- St. Mary - Corwin Regional Medical Center
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Thornton, Colorado, 미국, 80229
- North Suburban Medical Center
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Wheat Ridge, Colorado, 미국, 80033
- Exempla Lutheran Medical Center
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Connecticut
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Hartford, Connecticut, 미국, 06105
- Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center
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Hawaii
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Aiea, Hawaii, 미국, 96701
- Kapiolani Medical Center at Pali Momi
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Honolulu, Hawaii, 미국, 96813
- Cancer Research Center of Hawaii
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Honolulu, Hawaii, 미국, 96826
- Kapiolani Medical Center for Women and Children
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Honolulu, Hawaii, 미국, 96813
- OnCare Hawaii, Incorporated - Lusitana
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Honolulu, Hawaii, 미국, 96813
- Queen's Cancer Institute at Queen's Medical Center
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Honolulu, Hawaii, 미국, 96813
- Straub Clinic and Hospital, Incorporated
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Honolulu, Hawaii, 미국, 96817
- Hawaii Medical Center - East
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Honolulu, Hawaii, 미국, 96817
- OnCare Hawaii, Incorporated - Kuakini
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Honolulu, Hawaii, 미국, 96859
- Tripler Army Medical Center
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Lihue, Hawaii, 미국, 96766
- Kauai Medical Clinic
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Wailuku, Hawaii, 미국, 96793
- Maui Memorial Medical Center
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Wailuku, Hawaii, 미국, 96793
- Pacific Cancer Institute - Maui
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Idaho
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Boise, Idaho, 미국, 83706
- Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center
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Illinois
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Bloomington, Illinois, 미국, 61701
- St. Joseph Medical Center
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Bloomington%, Illinois, 미국, 61701
- Illinois CancerCare - Bloomington
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Canton, Illinois, 미국, 61520
- Illinois CancerCare - Canton
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Canton, Illinois, 미국, 61520
- Graham Hospital
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Carthage, Illinois, 미국, 62321
- Memorial Hospital
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Carthage, Illinois, 미국, 62321
- Illinois CancerCare - Carthage
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Eureka, Illinois, 미국, 61530
- Illinois CancerCare - Eureka
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Eureka, Illinois, 미국, 61530
- Eureka Community Hospital
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Galesburg, Illinois, 미국, 61401
- Illinois CancerCare - Galesburg
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Galesburg, Illinois, 미국, 61401
- Galesburg Clinic, PC
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Havana, Illinois, 미국, 62644
- Mason District Hospital
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Havana, Illinois, 미국, 62644
- Illinois CancerCare - Havana
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Kewanee, Illinois, 미국, 61443
- Illinois CancerCare - Kewanee Clinic
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Macomb, Illinois, 미국, 61455
- Illinois CancerCare - Macomb
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Macomb, Illinois, 미국, 61455
- Mcdonough District Hospital
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Moline, Illinois, 미국, 61265
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Moline, Illinois, 미국, 61265
- Trinity Cancer Center at Trinity Medical Center - 7th Street Campus
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Monmouth, Illinois, 미국, 61462
- Illinois CancerCare - Monmouth
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Monmouth, Illinois, 미국, 61462
- OSF Holy Family Medical Center
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Normal, Illinois, 미국, 61761
- Bromenn Regional Medical Center
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Normal, Illinois, 미국, 61761
- Community Cancer Center
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Normal, Illinois, 미국, 61761
- Illinois CancerCare - Community Cancer Center
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Ottawa, Illinois, 미국, 61350
- Community Hospital of Ottawa
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Ottawa, Illinois, 미국, 61350
- Oncology Hematology Associates of Central Illinois, PC - Ottawa
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Pekin, Illinois, 미국, 61554
- Cancer Treatment Center at Pekin Hospital
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Pekin, Illinois, 미국, 61603
- Illinois CancerCare - Pekin
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Peoria, Illinois, 미국, 61636
- Methodist Medical Center of Illinois
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Peoria, Illinois, 미국, 61614
- Proctor Hospital
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Peoria, Illinois, 미국, 61637
- OSF St. Francis Medical Center
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Peoria, Illinois, 미국, 61615
- CCOP - Illinois Oncology Research Association
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Peoria, Illinois, 미국, 61615
- Oncology Hematology Associates of Central Illinois, PC - Peoria
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Peru, Illinois, 미국, 61354
- Illinois CancerCare - Peru
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Peru, Illinois, 미국, 61354
- Illinois Valley Community Hospital
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Princeton, Illinois, 미국, 61356
- Perry Memorial Hospital
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Princeton, Illinois, 미국, 61356
- Illinois CancerCare - Princeton
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Spring Valley, Illinois, 미국, 61362
- Illinois CancerCare - Spring Valley
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Indiana
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Elkhart, Indiana, 미국, 46515
- Elkhart General Hospital
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Elkhart, Indiana, 미국, 46514
- Michiana Hematology-Oncology, PC - Elkhart
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Kokomo, Indiana, 미국, 46904
- Howard Community Hospital
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La Porte, Indiana, 미국, 46350
- Center for Cancer Therapy at LaPorte Hospital and Health Services
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Mishawaka, Indiana, 미국, 46545-1470
- Michiana Hematology-Oncology, PC - South Bend
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Mishawaka, Indiana, 미국, 46545-1470
- Saint Joseph Regional Medical Center
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Plymouth, Indiana, 미국, 46563
- Michiana Hematology Oncology PC - Plymouth
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South Bend, Indiana, 미국, 46601
- Memorial Hospital of South Bend
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South Bend, Indiana, 미국, 46601
- CCOP - Northern Indiana CR Consortium
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Westville, Indiana, 미국, 46391
- Michiana Hematology Oncology PC - La Porte
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Iowa
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Ames, Iowa, 미국, 50010
- McFarland Clinic, PC
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Bettendorf, Iowa, 미국, 52722
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Cedar Rapids, Iowa, 미국, 52403
- Cedar Rapids Oncology Associates
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Cedar Rapids, Iowa, 미국, 52403
- Mercy Regional Cancer Center at Mercy Medical Center
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Clive, Iowa, 미국, 50325
- Medical Oncology and Hematology Associates - West Des Moines
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Des Moines, Iowa, 미국, 50309
- CCOP - Iowa Oncology Research Association
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Des Moines, Iowa, 미국, 50309
- John Stoddard Cancer Center at Iowa Methodist Medical Center
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Des Moines, Iowa, 미국, 50309
- Medical Oncology and Hematology Associates at John Stoddard Cancer Center
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Des Moines, Iowa, 미국, 50314
- Medical Oncology and Hematology Associates at Mercy Cancer Center
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Des Moines, Iowa, 미국, 50314
- Mercy Cancer Center at Mercy Medical Center - Des Moines
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Des Moines, Iowa, 미국, 50316
- John Stoddard Cancer Center at Iowa Lutheran Hospital
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Mason City, Iowa, 미국, 50401
- Mercy Cancer Center at Mercy Medical Center - North Iowa
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Ottumwa, Iowa, 미국, 52501
- McCreery Cancer Center at Ottumwa Regional
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Sioux City, Iowa, 미국, 51101
- Siouxland Hematology-Oncology Associates, LLP
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Sioux City, Iowa, 미국, 51102
- Mercy Medical Center - Sioux City
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Sioux City, Iowa, 미국, 51104
- St. Luke's Regional Medical Center
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Kansas
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Chanute, Kansas, 미국, 66720
- Cancer Center of Kansas, PA - Chanute
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Dodge City, Kansas, 미국, 67801
- Cancer Center of Kansas, PA - Dodge City
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El Dorado, Kansas, 미국, 67042
- Cancer Center of Kansas, PA - El Dorado
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Fort Scott, Kansas, 미국, 66701
- Cancer Center of Kansas - Fort Scott
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Independence, Kansas, 미국, 67301
- Cancer Center of Kansas-Independence
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Kingman, Kansas, 미국, 67068
- Cancer Center of Kansas, PA - Kingman
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Lawrence, Kansas, 미국, 66044
- Lawrence Memorial Hospital
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Liberal, Kansas, 미국, 67901
- Cancer Center of Kansas, PA - Liberal
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McPherson, Kansas, 미국, 67460
- Cancer Center of Kansas, PA - McPherson
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Newton, Kansas, 미국, 67114
- Cancer Center of Kansas, PA - Newton
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Parsons, Kansas, 미국, 67357
- Cancer Center of Kansas, PA - Parsons
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Pratt, Kansas, 미국, 67124
- Cancer Center of Kansas, PA - Pratt
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Salina, Kansas, 미국, 67401
- Cancer Center of Kansas, PA - Salina
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Wellington, Kansas, 미국, 67152
- Cancer Center of Kansas, PA - Wellington
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Wichita, Kansas, 미국, 67208
- Cancer Center of Kansas, PA - Medical Arts Tower
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Wichita, Kansas, 미국, 67214
- Cancer Center of Kansas, PA - Wichita
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Wichita, Kansas, 미국, 67214
- CCOP - Wichita
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Wichita, Kansas, 미국, 67214
- Via Christi Cancer Center at Via Christi Regional Medical Center
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Wichita, Kansas, 미국, 67208
- Associates in Womens Health, PA - North Review
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Winfield, Kansas, 미국, 67156
- Cancer Center of Kansas, PA - Winfield
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Louisiana
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Baton Rouge, Louisiana, 미국, 70809
- Ochsner Health Center - Bluebonnet
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New Orleans, Louisiana, 미국, 70121
- CCOP - Ochsner
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New Orleans, Louisiana, 미국, 70121
- Ochsner Cancer Institute at Ochsner Clinic Foundation
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Michigan
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Adrian, Michigan, 미국, 49221
- Hickman Cancer Center at Bixby Medical Center
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Ann Arbor, Michigan, 미국, 48106-0995
- Saint Joseph Mercy Cancer Center
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Ann Arbor, Michigan, 미국, 48106
- CCOP - Michigan Cancer Research Consortium
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Battle Creek, Michigan, 미국, 49017
- Battle Creek Health System Cancer Care Center
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Big Rapids, Michigan, 미국, 49307
- Mecosta County Medical Center
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Dearborn, Michigan, 미국, 48123-2500
- Oakwood Cancer Center at Oakwood Hospital and Medical Center
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Escanaba, Michigan, 미국, 49431
- Green Bay Oncology, Limited - Escanaba
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Flint, Michigan, 미국, 48503
- Hurley Medical Center
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Flint, Michigan, 미국, 48503
- Genesys Hurley Cancer Institute
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Grand Rapids, Michigan, 미국, 49503
- Butterworth Hospital at Spectrum Health
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Grand Rapids, Michigan, 미국, 49503
- CCOP - Grand Rapids
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Grand Rapids, Michigan, 미국, 49503
- Lacks Cancer Center at Saint Mary's Health Care
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Grosse Pointe Woods, Michigan, 미국, 48236
- Van Elslander Cancer Center at St. John Hospital and Medical Center
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Iron Mountain, Michigan, 미국, 49801
- Dickinson County Healthcare System
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Jackson, Michigan, 미국, 49201
- Foote Memorial Hospital
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Lansing, Michigan, 미국, 48912-1811
- Sparrow Regional Cancer Center
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Livonia, Michigan, 미국, 48154
- St. Mary Mercy Hospital
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Monroe, Michigan, 미국, 48162
- Community Cancer Center of Monroe
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Monroe, Michigan, 미국, 48162
- Mercy Memorial Hospital - Monroe
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Muskegon, Michigan, 미국, 49443
- Mercy General Health Partners
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Pontiac, Michigan, 미국, 48341-2985
- St. Joseph Mercy Oakland
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Port Huron, Michigan, 미국, 48060
- Mercy Regional Cancer Center at Mercy Hospital
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Saginaw, Michigan, 미국, 48601
- Seton Cancer Institute at Saint Mary's - Saginaw
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Saint Joseph, Michigan, 미국, 49085
- Lakeside Cancer Specialists, PLLC
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St. Joseph, Michigan, 미국, 49085
- Lakeland Regional Cancer Care Center - St. Joseph
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Traverse City, Michigan, 미국, 49684
- Munson Medical Center
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Warren, Michigan, 미국, 48093
- St. John Macomb Hospital
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Minnesota
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Alexandria, Minnesota, 미국, 56308
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Bemidji, Minnesota, 미국, 56601
- MeritCare Bemidji
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Burnsville, Minnesota, 미국, 55337
- Fairview Ridges Hospital
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Coon Rapids, Minnesota, 미국, 55433
- Mercy and Unity Cancer Center at Mercy Hospital
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Duluth, Minnesota, 미국, 55805
- CCOP - Duluth
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Duluth, Minnesota, 미국, 55805-1983
- Duluth Clinic Cancer Center - Duluth
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Duluth, Minnesota, 미국, 55805
- Miller - Dwan Medical Center
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Edina, Minnesota, 미국, 55435
- Fairview Southdale Hospital
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Fridley, Minnesota, 미국, 55432
- Mercy and Unity Cancer Center at Unity Hospital
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Hutchinson, Minnesota, 미국, 55350
- Hutchinson Area Health Care
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Mankato, Minnesota, 미국, 56002
- Immanuel St. Joseph's
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Maplewood, Minnesota, 미국, 55109
- HealthEast Cancer Care at St. John's Hospital
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Maplewood, Minnesota, 미국, 55109
- Minnesota Oncology - Maplewood
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Minneapolis, Minnesota, 미국, 55407
- Virginia Piper Cancer Institute at Abbott - Northwestern Hospital
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Minneapolis, Minnesota, 미국, 55415
- Hennepin County Medical Center - Minneapolis
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New Ulm, Minnesota, 미국, 56073
- New Ulm Medical Center
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Robbinsdale, Minnesota, 미국, 55422-2900
- Humphrey Cancer Center at North Memorial Outpatient Center
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Rochester, Minnesota, 미국, 55905
- Mayo Clinic Cancer Center
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Saint Cloud, Minnesota, 미국, 56303
- CentraCare Clinic - River Campus
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Saint Cloud, Minnesota, 미국, 56303
- Coborn Cancer Center
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Saint Louis Park, Minnesota, 미국, 55416
- CCOP - Metro-Minnesota
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Saint Louis Park, Minnesota, 미국, 55416
- Park Nicollet Cancer Center
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Saint Paul, Minnesota, 미국, 55102
- United Hospital
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Shakopee, Minnesota, 미국, 55379
- St. Francis Cancer Center at St. Francis Medical Center
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St. Paul, Minnesota, 미국, 55101
- Regions Hospital Cancer Care Center
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Stillwater, Minnesota, 미국, 55082
- Lakeview Hospital
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Waconia, Minnesota, 미국, 55387
- Ridgeview Medical Center
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Willmar, Minnesota, 미국, 56201
- Willmar Cancer Center at Rice Memorial Hospital
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Woodbury, Minnesota, 미국, 55125
- Minnesota Oncology - Woodbury
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Missouri
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Cape Girardeau, Missouri, 미국, 63703
- Southeast Cancer Center
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Jefferson City, Missouri, 미국, 65109
- Goldschmidt Cancer Center
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Saint Louis, Missouri, 미국, 63131
- Missouri Baptist Cancer Center
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Saint Louis, Missouri, 미국, 63141
- Comprehensive Cancer Care, PC
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Montana
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Billings, Montana, 미국, 59101
- CCOP - Montana Cancer Consortium
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Billings, Montana, 미국, 59101
- St. Vincent Healthcare Cancer Care Services
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Billings, Montana, 미국, 59107-7000
- Billings Clinic - Downtown
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Billings, Montana, 미국, 59102
- Hematology-Oncology Centers of the Northern Rockies - Billings
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Bozeman, Montana, 미국, 59715
- Bozeman Deaconess Cancer Center
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Butte, Montana, 미국, 59701
- St. James Healthcare Cancer Care
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Great Falls, Montana, 미국, 59405
- Great Falls Clinic - Main Facility
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Great Falls, Montana, 미국, 59405
- Sletten Cancer Institute at Benefis Healthcare
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Havre, Montana, 미국, 59501
- Northern Montana Hospital
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Helena, Montana, 미국, 59601
- St. Peter's Hospital
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Kalispell, Montana, 미국, 59901
- Kalispell Regional Medical Center
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Kalispell, Montana, 미국, 59901
- Glacier Oncology, PLLC
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Kalispell, Montana, 미국, 59901
- Kalispell Medical Oncology at KRMC
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Missoula, Montana, 미국, 59807-7877
- Montana Cancer Specialists at Montana Cancer Center
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Missoula, Montana, 미국, 59807
- Montana Cancer Center at St. Patrick Hospital and Health Sciences Center
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Nebraska
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Lincoln, Nebraska, 미국, 68510
- Cancer Resource Center - Lincoln
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Omaha, Nebraska, 미국, 68106
- CCOP - Missouri Valley Cancer Consortium
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Omaha, Nebraska, 미국, 68122
- Immanuel Medical Center
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Omaha, Nebraska, 미국, 68124
- Alegant Health Cancer Center at Bergan Mercy Medical Center
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Omaha, Nebraska, 미국, 68131-2197
- Creighton University Medical Center
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Omaha, Nebraska, 미국, 68130
- Lakeside Hospital
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North Dakota
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Bismarck, North Dakota, 미국, 58501
- Bismarck Cancer Center
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Bismarck, North Dakota, 미국, 58501
- Medcenter One Hospital Cancer Care Center
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Bismarck, North Dakota, 미국, 58501
- Mid Dakota Clinic, PC
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Bismarck, North Dakota, 미국, 58502
- St. Alexius Medical Center Cancer Center
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Fargo, North Dakota, 미국, 58122
- CCOP - MeritCare Hospital
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Fargo, North Dakota, 미국, 58102
- MeritCare Broadway
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Fargo, North Dakota, 미국, 58122
- Roger Maris Cancer Center at MeritCare Hospital
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Ohio
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Bowling Green, Ohio, 미국, 43402
- Wood County Oncology Center
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Chillicothe, Ohio, 미국, 45601
- Adena Regional Medical Center
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Columbus, Ohio, 미국, 43214-3998
- Riverside Methodist Hospital Cancer Care
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Columbus, Ohio, 미국, 43222
- Mount Carmel Health - West Hospital
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Columbus, Ohio, 미국, 43215
- CCOP - Columbus
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Columbus, Ohio, 미국, 43215
- Grant Medical Center Cancer Care
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Columbus, Ohio, 미국, 43228
- Doctors Hospital at Ohio Health
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Delaware, Ohio, 미국, 43015
- Grady Memorial Hospital
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Elyria, Ohio, 미국, 44035
- Community Cancer Center
-
Elyria, Ohio, 미국, 44035
- Hematology Oncology Center
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Lancaster, Ohio, 미국, 43130
- Fairfield Medical Center
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Lima, Ohio, 미국, 45804
- Lima Memorial Hospital
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Marietta, Ohio, 미국, 45750
- Strecker Cancer Center at Marietta Memorial Hospital
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Maumee, Ohio, 미국, 43537-1839
- Northwest Ohio Oncology Center
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Mount Vernon, Ohio, 미국, 43050
- Knox Community Hospital
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Newark, Ohio, 미국, 43055
- Licking Memorial Cancer Care Program at Licking Memorial Hospital
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Norwalk, Ohio, 미국, 44857
- Fisher-Titus Medical Center
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Oregon, Ohio, 미국, 43616
- St. Charles Mercy Hospital
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Oregon, Ohio, 미국, 43616
- Toledo Clinic - Oregon
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Portsmouth, Ohio, 미국, 45662
- Southern Ohio Medical Center Cancer Center
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Sandusky, Ohio, 미국, 44870
- North Coast Cancer Care, Incorporated
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Springfield, Ohio, 미국, 45505
- Community Hospital of Springfield and Clark County
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Sylvania, Ohio, 미국, 43560
- Flower Hospital Cancer Center
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Tiffin, Ohio, 미국, 44883
- Mercy Hospital of Tiffin
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Toledo, Ohio, 미국, 43608
- St. Vincent Mercy Medical Center
-
Toledo, Ohio, 미국, 43606
- Toledo Hospital
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Toledo, Ohio, 미국, 43614
- Medical University of Ohio Cancer Center
-
Toledo, Ohio, 미국, 43617
- CCOP - Toledo Community Hospital
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Toledo, Ohio, 미국, 43623
- Toledo Clinic, Incorporated - Main Clinic
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Toledo, Ohio, 미국, 43623
- St. Anne Mercy Hospital
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Wauseon, Ohio, 미국, 43567
- Fulton County Health Center
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Westerville, Ohio, 미국, 43081
- Mount Carmel St. Ann's Cancer Center
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Zanesville, Ohio, 미국, 43701
- Genesis - Good Samaritan Hospital
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Oklahoma
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Tulsa, Oklahoma, 미국, 74136
- Natalie Warren Bryant Cancer Center at St. Francis Hospital
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Oregon
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Clackamas, Oregon, 미국, 97015
- Clackamas Radiation Oncology Center
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Milwaukie, Oregon, 미국, 97222
- Providence Milwaukie Hospital
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Newberg, Oregon, 미국, 97132
- Providence Newberg Medical Center
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Oregon City, Oregon, 미국, 97045
- Willamette Falls Hospital
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Portland, Oregon, 미국, 97213-2967
- Providence Cancer Center at Providence Portland Medical Center
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Portland, Oregon, 미국, 97225
- CCOP - Columbia River Oncology Program
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Portland, Oregon, 미국, 97225
- Providence St. Vincent Medical Center
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Pennsylvania
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Danville, Pennsylvania, 미국, 17822-0001
- Geisinger Cancer Institute at Geisinger Health
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Hazleton, Pennsylvania, 미국, 18201
- Geisinger Hazleton Cancer Center
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State College, Pennsylvania, 미국, 16801
- Geisinger Medical Group - Scenery Park
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Wilkes-Barre, Pennsylvania, 미국, 18711
- Frank M. and Dorothea Henry Cancer Center at Geisinger Wyoming Valley Medical Center
-
-
South Dakota
-
Rapid City, South Dakota, 미국, 57701
- Rapid City Regional Hospital
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Sioux Falls, South Dakota, 미국, 57117-5039
- Sanford Cancer Center at Sanford USD Medical Center
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-
Virginia
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Fredericksburg, Virginia, 미국, 22401
- Fredericksburg Oncology, Incorporated
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Richmond, Virginia, 미국, 23298-0037
- Virginia Commonwealth University Massey Cancer Center
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-
Washington
-
Seattle, Washington, 미국, 98101
- Virginia Mason Medical Center
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Seattle, Washington, 미국, 98101
- CCOP - Virginia Mason Research Center
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Vancouver, Washington, 미국, 98664
- Southwest Washington Medical Center Cancer Center
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-
Wisconsin
-
Chippewa Falls, Wisconsin, 미국, 54729
- Marshfield Clinic - Chippewa Center
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Eau Claire, Wisconsin, 미국, 54701
- Marshfield Clinic Cancer Care at Regional Cancer Center
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Fond du Lac, Wisconsin, 미국, 54935
- Central Wisconsin Cancer Program at Agnesian HealthCare
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Green Bay, Wisconsin, 미국, 54307-3508
- St. Vincent Hospital Regional Cancer Center
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Green Bay, Wisconsin, 미국, 54301-3526
- Green Bay Oncology, Limited at St. Vincent Hospital Regional Cancer Center
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Green Bay, Wisconsin, 미국, 54303
- Green Bay Oncology, Limited at St. Mary's Hospital
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Green Bay, Wisconsin, 미국, 54303
- St. Mary's Hospital Medical Center - Green Bay
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Manitowoc, Wisconsin, 미국, 54221-1450
- Holy Family Memorial Medical Center Cancer Care Center
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Marinette, Wisconsin, 미국, 54143
- Bay Area Cancer Care Center at Bay Area Medical Center
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Marshfield, Wisconsin, 미국, 54449
- Marshfield Clinic - Marshfield Center
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Minocqua, Wisconsin, 미국, 54548
- Marshfield Clinic - Lakeland Center
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Oconto Falls, Wisconsin, 미국, 54154
- Green Bay Oncology, Limited - Oconto Falls
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Rhinelander, Wisconsin, 미국, 54501
- Ministry Medical Group at Saint Mary's Hospital
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Rice Lake, Wisconsin, 미국, 54868
- Marshfield Clinic - Indianhead Center
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Sheboygan, Wisconsin, 미국, 53081
- St. Nicholas Hospital
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Stevens Point, Wisconsin, 미국, 54481
- Marshfield Clinic at Saint Michael's Hospital
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Sturgeon Bay, Wisconsin, 미국, 54235
- Green Bay Oncology, Limited - Sturgeon Bay
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Weston, Wisconsin, 미국, 54476
- Marshfield Clinic - Weston Center
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Wisconsin Rapids, Wisconsin, 미국, 54494
- Marshfield Clinic - Wisconsin Rapids Center
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Wyoming
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Sheridan, Wyoming, 미국, 82801
- Welch Cancer Center at Sheridan Memorial Hospital
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-
참여기준
연구원은 적격성 기준이라는 특정 설명에 맞는 사람을 찾습니다. 이러한 기준의 몇 가지 예는 개인의 일반적인 건강 상태 또는 이전 치료입니다.
자격 기준
공부할 수 있는 나이
18년 이상 (성인, 고령자)
건강한 자원 봉사자를 받아들입니다
아니
연구 대상 성별
모두
샘플링 방법
비확률 샘플
연구 인구
Patients diagnosed with cancer who are planning to receive paclitaxel IV at least 175 mg/m^2 at 2-4 week intervals (course duration of 2, 3, or 4 weeks, respectively) or 70-90 mg/m^2 weekly (3 out of 4 weeks allowed).
설명
DISEASE CHARACTERISTICS:
- Diagnosis of cancer
Planning to receive paclitaxel IV (excluding paclitaxel albumin-stabilized nanoparticle formulation [nab-paclitaxel]) according to one of the following dosing schedules:
- At least 175 mg/m^2 at 2-4 week intervals (course duration of 2, 3, or 4 weeks, respectively)
- 70-90 mg/m^2 weekly (3 out of 4 weeks allowed)
PATIENT CHARACTERISTICS:
- ECOG performance status 0-1
- Life expectancy > 6 months
- Able to complete questionnaires (alone or with assistance)
- Willing to provide required biological specimens
- No prior or concurrent peripheral neuropathy (from diabetes or other causes)
- No prior or concurrent fibromyalgia
PRIOR CONCURRENT THERAPY:
- See Disease Characteristics
- No prior paclitaxel or neurotoxic chemotherapy drugs, including other taxanes, platinum agents, vinca alkaloids, or epothilones
- No concurrent neutrophil colony-stimulating factor therapy
공부 계획
이 섹션에서는 연구 설계 방법과 연구가 측정하는 내용을 포함하여 연구 계획에 대한 세부 정보를 제공합니다.
연구는 어떻게 설계됩니까?
디자인 세부사항
코호트 및 개입
그룹/코호트 |
개입 / 치료 |
|---|---|
|
Group I
Patients complete pain questionnaires at baseline, 2-8 days after each weekly paclitaxel treatment given in combination with a neurotoxic agent, and then monthly for 1 year.
Information about the type, location, and duration of pain and neuropathy as well as types of interventions used to manage the pain symptoms and the patients' pain responses is collected.
|
|
|
Group II
Patients complete pain questionnaires at baseline, 2-8 days after each weekly paclitaxel treatment not given in combination with a neurotoxic agent, and then monthly for 1 year.
Information about the type, location, and duration of pain and neuropathy as well as types of interventions used to manage the pain symptoms and the patients' pain responses is collected.
|
|
|
Group III
Patients complete pain questionnaires at baseline, 2-8 days after each 2-4 week paclitaxel treatment given in combination with a neurotoxic agent, and then monthly for 1 year.
Information about the type, location, and duration of pain and neuropathy as well as types of interventions used to manage the pain symptoms and the patients' pain responses is collected.
|
|
|
Group IV
Patients complete pain questionnaires at baseline, 2-8 days after each 2-4 week paclitaxel treatment not given in combination with a neurotoxic agent, and then monthly for 1 year.
Information about the type, location, and duration of pain and neuropathy as well as types of interventions used to manage the pain symptoms and the patients' pain responses is collected.
|
연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
기간 |
|---|---|
|
Maximum of the worst pain scores from the initiation of paclitaxel therapy (day 1) until day 7 (first week of therapy)
기간: Up to day 7
|
Up to day 7
|
2차 결과 측정
결과 측정 |
기간 |
|---|---|
|
Maximum of the average pain score
기간: Up to 12 months
|
Up to 12 months
|
|
Area under the curve of worst, average, and least pain
기간: Up to 12 months
|
Up to 12 months
|
|
Worst pain reported for the overall week
기간: Up to 12 months
|
Up to 12 months
|
|
Rate of non-prescription pain medication use
기간: Up to 12 months
|
Up to 12 months
|
|
Rate of opioid use
기간: Up to 12 months
|
Up to 12 months
|
|
Rate of other pain therapy use
기간: Up to 12 months
|
Up to 12 months
|
|
Correlation of the worst pain score for the first dose of therapy with subsequent neuropathy scores
기간: Up to 12 months
|
Up to 12 months
|
공동 작업자 및 조사자
여기에서 이 연구와 관련된 사람과 조직을 찾을 수 있습니다.
간행물 및 유용한 링크
연구에 대한 정보 입력을 담당하는 사람이 자발적으로 이러한 간행물을 제공합니다. 이것은 연구와 관련된 모든 것에 관한 것일 수 있습니다.
일반 간행물
- Reeves BN, Dakhil SR, Sloan JA, Wolf SL, Burger KN, Kamal A, Le-Lindqwister NA, Soori GS, Jaslowski AJ, Kelaghan J, Novotny PJ, Lachance DH, Loprinzi CL. Further data supporting that paclitaxel-associated acute pain syndrome is associated with development of peripheral neuropathy: North Central Cancer Treatment Group trial N08C1. Cancer. 2012 Oct 15;118(20):5171-8. doi: 10.1002/cncr.27489. Epub 2012 Mar 13.
- Loprinzi CL, Reeves BN, Dakhil SR, Sloan JA, Wolf SL, Burger KN, Kamal A, Le-Lindqwister NA, Soori GS, Jaslowski AJ, Novotny PJ, Lachance DH. Natural history of paclitaxel-associated acute pain syndrome: prospective cohort study NCCTG N08C1. J Clin Oncol. 2011 Apr 10;29(11):1472-8. doi: 10.1200/JCO.2010.33.0308. Epub 2011 Mar 7.
연구 기록 날짜
이 날짜는 ClinicalTrials.gov에 대한 연구 기록 및 요약 결과 제출의 진행 상황을 추적합니다. 연구 기록 및 보고된 결과는 공개 웹사이트에 게시되기 전에 특정 품질 관리 기준을 충족하는지 확인하기 위해 국립 의학 도서관(NLM)에서 검토합니다.
연구 주요 날짜
연구 시작
2009년 2월 1일
기본 완료 (실제)
2011년 4월 1일
연구 완료 (실제)
2013년 5월 1일
연구 등록 날짜
최초 제출
2009년 3월 10일
QC 기준을 충족하는 최초 제출
2009년 3월 10일
처음 게시됨 (추정)
2009년 3월 11일
연구 기록 업데이트
마지막 업데이트 게시됨 (추정)
2016년 7월 14일
QC 기준을 충족하는 마지막 업데이트 제출
2016년 7월 12일
마지막으로 확인됨
2016년 7월 1일
추가 정보
이 정보는 변경 없이 clinicaltrials.gov 웹사이트에서 직접 가져온 것입니다. 귀하의 연구 세부 정보를 변경, 제거 또는 업데이트하도록 요청하는 경우 register@clinicaltrials.gov. 문의하십시오. 변경 사항이 clinicaltrials.gov에 구현되는 즉시 저희 웹사이트에도 자동으로 업데이트됩니다. .