이 페이지는 자동 번역되었으며 번역의 정확성을 보장하지 않습니다. 참조하십시오 영문판 원본 텍스트의 경우.

The Study of Cognitive Rehabilitation Effectiveness for Mild Traumatic Brain Injury (SCORE)

2015년 2월 6일 업데이트: Amy Bowles, M.D., Brooke Army Medical Center

Phase IV Study of Cognitive Rehabilitation Effectiveness for Mild Traumatic Brain Injury

The objective of this trial is to evaluate the effectiveness of cognitive rehabilitation in OIF/OEF service members with a history of mild traumatic brain injury and persistent (3-24 months post injury) cognitive complaints. This is a prospective, randomized, control treatment trial of cognitive rehabilitation for OEF/OIF Service Members with a history of mild traumatic brain injury (mTBI) and persistent (3-24 months post-injury) cognitive complaints. Subjects will be recruited from consecutive patient referrals to the TBI Service at SAMMC-North. Patients who meet eligibility criteria and consent to participate in the treatment trial will be randomly assigned to one of four, 6-week treatment arms of the study. Subjects will be evaluated prior to the start of treatment and 3, 6, 12, and 18 weeks following the initiation of the study. The total number of patients to be studied is 160 (maximum), which is approximately 20 patients per month.

연구 개요

상태

완전한

정황

개입 / 치료

상세 설명

This is a prospective, randomized, control treatment trial of cognitive rehabilitation for OEF/OIF Service Members with a history of mild traumatic brain injury (mTBI) and persistent (3-24 months post-injury) cognitive complaints. Subjects will be recruited from consecutive patient referrals to the TBI Service at SAMMC-North. Patients who meet eligibility criteria and consent to participate in the treatment trial will be randomly assigned to one of four, 6-week treatment arms of the study: 1. Psychoeducational control group; 2. Non-therapist directed, computerized cognitive rehabilitation; 3. Therapist-directed individualized cognitive rehabilitation; and 4. Integrated interdisciplinary cognitive rehabilitation combined with cognitive-behavioral psychotherapy. (Components of the treatment arms are described in detail in section 4.6; Research Design and Methods.) All subjects enrolled in the study will receive the standard of care in management of chronic post-concussive symptoms, consistent with the VA/DoD Clinical Practice Guidelines for the Management of Concussion/mild TBI (Barth et al., 2009), regardless of treatment assignment. The standard of care includes provision of patient education materials (adapted from existing studies to address more persistent rather than acute symptom management), regular scheduled follow-up with a medical provider every three weeks, and symptom-based treatment of post-concussive complaints (e.g., medication trials for headache and co-occurring psychiatric disorders, physical therapy for vestibular complaints, case management, and supportive counseling with social work for soldiers assigned to the Warriors-in-Transition Battalion). Study participants who are assigned to treatment arms 2, 3, or 4 will additionally receive manualized cognitive rehabilitation therapies during the 6-week treatment phase of the study. Cognitive rehabilitation treatment intensity (i.e., number of hours of treatment per week) will be matched for individuals assigned to treatment arms 2, 3, or 4. Participants assigned to the control treatment group (treatment arm 1) will be offered individualized cognitive rehabilitation therapy if their cognitive complaints do not abate following the completion of the six-week treatment trial.

Study participants will be evaluated prior to the initiation of treatment, as well as at 3-weeks, 6-weeks, 12-weeks, and 18-weeks following the start of treatment. Study evaluators will be blind to treatment assignment. Pre-treatment baseline assessments and peri-/post-treatment outcome assessments will include demographic information, injury-related variables, self-report inventories, performance on neuropsychological testing, and functional status (e.g., work status; healthcare utilization). Detailed descriptions of the data to be collected including primary and secondary outcome measures, as well as co-variate measures can be found in section 4.8: Instrumentation.

연구 유형

중재적

등록 (실제)

143

단계

  • 4단계

연락처 및 위치

이 섹션에서는 연구를 수행하는 사람들의 연락처 정보와 이 연구가 수행되는 장소에 대한 정보를 제공합니다.

연구 장소

  • 미국
    • Texas
      • San Antonio, Texas, 미국, 78234
        • Brooke Army Medical Center

참여기준

연구원은 적격성 기준이라는 특정 설명에 맞는 사람을 찾습니다. 이러한 기준의 몇 가지 예는 개인의 일반적인 건강 상태 또는 이전 치료입니다.

자격 기준

공부할 수 있는 나이

18년 이상 (성인, 고령자)

건강한 자원 봉사자를 받아들입니다

아니

연구 대상 성별

모두

설명

Inclusion Criteria:

  • Diagnosis of mTBI as defined in the VA/DoD Clinical Practice Guidelines for the Management of Concussion/mild TBI (Barth et al., 2009) which occurred during deployment in support of OEF/OIF within 3-24 months of study enrollment;
  • Presence of cognitive complaints (NSI score of 3 or higher on any of the four cognitive symptoms)
  • Ability to understand and communicate in English.

Exclusion Criteria:

  • Medical/psychiatric/neurologic co-morbidities of: blindness/low vision; uncontrolled seizure disorder; psychosis; history of moderate, severe TBI or penetrating BI; or Spinal Cord Injury with no use of upper extremities;
  • Active participation in intensive (> 5 appointments per week) treatment for amputation, orthopedic trauma, burns, substance abuse, or post-traumatic stress disorder which would preclude full participation in an intensive cognitive rehabilitation program; or
  • Daily use of narcotic pain medication(s).

공부 계획

이 섹션에서는 연구 설계 방법과 연구가 측정하는 내용을 포함하여 연구 계획에 대한 세부 정보를 제공합니다.

연구는 어떻게 설계됩니까?

디자인 세부사항

  • 주 목적: 치료
  • 할당: 무작위
  • 중재 모델: 요인 할당
  • 마스킹: 더블

무기와 개입

참가자 그룹 / 팔
개입 / 치료
다른: Standard of Care for mTBI Provider Arm
Arm 1: Psychoeducational Control Group. Individuals assigned to arm 1 will receive psychoeducational materials specifically adapted for persistent management of symptoms and routine follow-up with medical providers (every three weeks). Additionally, subjects assigned to this group will receive medical care (e.g., psychopharmacological management of depression) and/or referral for symptom management (e.g., vestibular rehabilitation) of non-cognitive complaints, consistent with the current standard of care treatment model for managing post-concussive symptoms (see Figure below adapted with permission from authors; Brenner et al., 2009).
행동: Informational Handout/Provider Visits
Provider based visits every three weeks and informational handout given to patient in regulation with current standard of care procedures.
실험적: Computer Based Therapy Group
Arm 2: Non-therapist directed computerized cognitive rehabilitation. Individuals assigned to treatment arm 2 will receive ten hours of in-clinic, computerized treatment per week throughout the 6-week treatment trial. Participants will be scheduled for 2 hours per day, proctored by clinic staff (certified recreation therapist or neuropsychology technician) who will be responsible for recording daily performance, providing positive reinforcement of participation, and effort. Computer programs selected for this treatment trial include both skill-specific training (e.g., attention processes) and general cognitive activation. These computer programs are commercially available and advertised as "brain fitness" or "brain training."
행동: Informational Handout/Provider Visits
Provider based visits every three weeks and informational handout given to patient in regulation with current standard of care procedures.
행동: Brainworks
POSIT
다른 이름들:
  • POSIT
실험적: Cognitive Rehab Group
Arm 3: Therapist-directed individualized cognitive rehabilitation. Individuals assigned to treatment arm 3 will receive 10 hours of individual and group cognitive rehabilitation treatment (including homework assignments) per week conducted by credentialed speech therapists and occupational therapists. The treatment components will include five hours of weekly individual therapy (one-hour sessions; two hours focused on compensatory strategies and three hours focused on restorative strategies), two hours of weekly group therapy (one hour sessions focused on compensatory strategies), and three hours of weekly computer-based "homework" proctored by clinic staff who will be responsible for recording performance, and providing positive reinforcement of participation and effort.
행동: Informational Handout/Provider Visits
Provider based visits every three weeks and informational handout given to patient in regulation with current standard of care procedures.
행동: Cognitive Rehab
APT-III, Other standard individual and group interventions.
다른 이름들:
  • APT-III
실험적: Cognitive and Psychological Based Rehab
Arm 4: Integrated interdisciplinary cognitive rehabilitation combined with cognitive-behavioral psychotherapy. Individuals assigned to treatment arm 4 will receive 10 hours of individual and group treatment per week conducted by credentialed therapists and doctoral-level psychologists. The treatment components will include four hours of weekly 1 hr individual therapy sessions; 2 hrs of cognitive rehabilitation, 1 hr of cognitive rehab & 1 hr of individual psychotherapy targeting anxiety/combat stress symptoms including relaxation training & exposure therapy and cognitive-behavioral principles, 3 hrs of weekly group therapy & three hours of weekly "homework" including 30-mins relaxation training, 30-mins cognitive-behavioral psychotherapy homework, and 2 hrs of computerized cognitive rehabilitation exercises proctored by clinic staff.
행동: Informational Handout/Provider Visits
Provider based visits every three weeks and informational handout given to patient in regulation with current standard of care procedures.
행동: Cognitive Rehab
APT-III, Other standard individual and group interventions.
다른 이름들:
  • APT-III

연구는 무엇을 측정합니까?

주요 결과 측정

결과 측정
측정값 설명
기간
Emotional Functioning
기간: Baseline

Symptom Checklist-90-Revised (SCL-90-R)

Global Severity Index and 9 subscales:

Somatization; Obsessive-Compulsive; Interpersonal Sensitivity; Depression; Anxiety; Hostility; Phobic Anxiety; Paranoid Ideation, and Psychoticism
Baseline
Cognitive Efficiency
기간: Baseline

Paced Auditory Serial Addition Test (PASAT)

  • correct trial 1
  • correct trial 2
  • correct trial 3
  • correct trial 4 Sum of trials 1-4
Baseline
Functional Behaviors
기간: Baseline
Key Behaviors Change Inventory (KBCI) Total score Inattention- raw & T-score Impulsivity- raw & T-score Unawareness of Problems - raw & T-score Apathy - raw & T-score Interpersonal Difficulties - raw & T-score Communication Problems - raw & T-score Somatic Difficulties - raw & T-score Emotional Adjustment - raw & T-score 64 individual items
Baseline
Emotional Functioning
기간: 3 Weeks

Symptom Checklist-90-Revised (SCL-90-R)

Global Severity Index and 9 subscales:

Somatization; Obsessive-Compulsive; Interpersonal Sensitivity; Depression; Anxiety; Hostility; Phobic Anxiety; Paranoid Ideation, and Psychoticism
3 Weeks
Emotional Functioning
기간: 6 Weeks

Symptom Checklist-90-Revised (SCL-90-R)

Global Severity Index and 9 subscales:

Somatization; Obsessive-Compulsive; Interpersonal Sensitivity; Depression; Anxiety; Hostility; Phobic Anxiety; Paranoid Ideation, and Psychoticism
6 Weeks
Emotional Functioning
기간: 12 Weeks

Symptom Checklist-90-Revised (SCL-90-R)

Global Severity Index and 9 subscales:

Somatization; Obsessive-Compulsive; Interpersonal Sensitivity; Depression; Anxiety; Hostility; Phobic Anxiety; Paranoid Ideation, and Psychoticism
12 Weeks
Emotional Functioning
기간: 18 Weeks

Symptom Checklist-90-Revised (SCL-90-R)

Global Severity Index and 9 subscales:

Somatization; Obsessive-Compulsive; Interpersonal Sensitivity; Depression; Anxiety; Hostility; Phobic Anxiety; Paranoid Ideation, and Psychoticism
18 Weeks
Cognitive Efficiency
기간: 3 Weeks

Paced Auditory Serial Addition Test (PASAT)

  • correct trial 1
  • correct trial 2
  • correct trial 3
  • correct trial 4 Sum of trials 1-4
3 Weeks
Cognitive Efficiency
기간: 6 Weeks

Paced Auditory Serial Addition Test (PASAT)

  • correct trial 1
  • correct trial 2
  • correct trial 3
  • correct trial 4 Sum of trials 1-4
6 Weeks
Cognitive Efficiency
기간: 12 Weeks

Paced Auditory Serial Addition Test (PASAT)

  • correct trial 1
  • correct trial 2
  • correct trial 3
  • correct trial 4 Sum of trials 1-4
12 Weeks
Cognitive Efficiency
기간: 18 Weeks

Paced Auditory Serial Addition Test (PASAT)

  • correct trial 1
  • correct trial 2
  • correct trial 3
  • correct trial 4 Sum of trials 1-4
18 Weeks
Functional Behaviors
기간: 3 Weeks
Key Behaviors Change Inventory (KBCI) Total score Inattention- raw & T-score Impulsivity- raw & T-score Unawareness of Problems - raw & T-score Apathy - raw & T-score Interpersonal Difficulties - raw & T-score Communication Problems - raw & T-score Somatic Difficulties - raw & T-score Emotional Adjustment - raw & T-score 64 individual items
3 Weeks
Functional Behaviors
기간: 6 Weeks
Key Behaviors Change Inventory (KBCI) Total score Inattention- raw & T-score Impulsivity- raw & T-score Unawareness of Problems - raw & T-score Apathy - raw & T-score Interpersonal Difficulties - raw & T-score Communication Problems - raw & T-score Somatic Difficulties - raw & T-score Emotional Adjustment - raw & T-score 64 individual items
6 Weeks
Functional Behaviors
기간: 12 Weeks
Key Behaviors Change Inventory (KBCI) Total score Inattention- raw & T-score Impulsivity- raw & T-score Unawareness of Problems - raw & T-score Apathy - raw & T-score Interpersonal Difficulties - raw & T-score Communication Problems - raw & T-score Somatic Difficulties - raw & T-score Emotional Adjustment - raw & T-score 64 individual items
12 Weeks
Functional Behaviors
기간: 18 Weeks
Key Behaviors Change Inventory (KBCI) Total score Inattention- raw & T-score Impulsivity- raw & T-score Unawareness of Problems - raw & T-score Apathy - raw & T-score Interpersonal Difficulties - raw & T-score Communication Problems - raw & T-score Somatic Difficulties - raw & T-score Emotional Adjustment - raw & T-score 64 individual items
18 Weeks

2차 결과 측정

결과 측정
측정값 설명
기간
Fatigue
기간: Baseline
Fatigue Severity Scale (FSS) Total Raw scale 9 individual items
Baseline
Post-Concussive Symptoms
기간: Baseline
Neurobehavioral Symptom Inventory Total Raw scale 22 individual items
Baseline
Self Reported Quality of Life
기간: Baseline

World Health Organization Brief Quality of Life Scale (WHO-QOL-BREF) Total transformed score

Total score for each of the 5 subscale domains:

Overall Functioning Physical Capacity Psychological Social Relationships Environment
Baseline
Neuropsychological Status
기간: Baseline
Neuropsychological Global Composite Score Average normative t-score of: [CVLT-2 sum trials 1-5, D-KEFS Verbal Fluency total score, Trail Making Test - part B only, WAIS-IV Processing Speed, Working, CVLT- 2 Trial 1, CVLT-2 Trial 2, CVLT- 2 Trial 3, CVLT-2 Trial 4, CVLT-2 Trial 5, CVLT-2 Total Trials 1-5, CVLT-2 Total Trials 1-5 (T-score), CVLT-2 List B, SDFR, SDCR, LDFR, LDCR, total perseverations,total intrusions CVLT-2 LD recognition hits CVLT-2 LD recognition FP errors Trails part A, Trails part B, Trails part A, Trails part B, WAIS-IV Processing Speed Index, WAIS-IV Symbol Search
Baseline
Self Reported Alcohol Use Behaviors
기간: Baseline
Alcohol Use Disorders Identification Test (AUDIT) Summary Socre; 10 individual items
Baseline
Post-Traumatic Stress Symptomatology
기간: 18 Weeks
Post-Traumatic Stress Checklist-Military Form (PCL-M) Total Raw Socre 17 items
18 Weeks
Self Reported Headache Disability
기간: Baseline
Headache Impact Test-6 (HIT-6) Total Weighted Score
Baseline
Health Related (Cognition) Locus of Control
기간: Baseline
Multidimensional Health Locus of Control Scale (MHLCS-Form C) Internal subscale-total raw Chance subscale-total raw Powerful others subscale-total raw Doctors subscale-total raw Other people subscale-total raw
Baseline
Perceived Self-Efficacy (Cognition)
기간: Baseline
Self-Efficacy for Symptom Management Scale SEsx total SEsocial subscale SEemotional subscale SEcognitvie subscale 13 individual items
Baseline
Attribution of Cognitive Symptoms
기간: Baseline
Cognitive Symptom Attribution Scale 7 individual items
Baseline
Therapist-Rated Patient Engagement in Treatment
기간: Week 6 of treatment
Rehabilitation Intensity of Therapy Scale (RITS) Weekly average rating (weeks 1-6)
Week 6 of treatment
Post-Concussive Symptoms
기간: 6 Weeks
Neurobehavioral Symptom Inventory (NSI) Total Raw scale 22 individual items
6 Weeks
Post-Concussive Symptoms
기간: 12 weeks
Neurobehavioral Symptom Inventory (NSI) Total Raw scale 22 individual items
12 weeks
Post-Concussive Symptoms
기간: 18 weeks
Neurobehavioral Symptom Inventory (NSI) Total Raw scale 22 individual items
18 weeks
Fatigue
기간: 6 weeks
Fatigue Severity Scale (FSS) Total Raw scale 9 individual items
6 weeks
Fatigue
기간: 12 Weeks
Fatigue Severity Scale (FSS) Total Raw scale 9 individual items
12 Weeks
Fatigue
기간: 18 Weeks
Fatigue Severity Scale (FSS) Total Raw scale 9 individual items
18 Weeks
Change in Healthcare Utilization
기간: 30 days prior to Baseline and 6 months post Baseline
Summed total number of appointments 30 days prior to study enrollment and summed total number of appointments for 30 days between 5 and 6 months post-treatment.
30 days prior to Baseline and 6 months post Baseline
Self Reported Quality of Life
기간: 6 weeks

World Health Organization Brief Quality of Life Scale (WHO-QOL-BREF) Total transformed score

Total score for each of the 5 subscale domains:

Overall Functioning Physical Capacity Psychological Social Relationships Environment
6 weeks
Self Reported Quality of Life
기간: 12 weeks

World Health Organization Brief Quality of Life Scale (WHO-QOL-BREF) Total transformed score

Total score for each of the 5 subscale domains:

Overall Functioning Physical Capacity Psychological Social Relationships Environment
12 weeks
Self Reported Quality of Life
기간: 18 weeks

World Health Organization Brief Quality of Life Scale (WHO-QOL-BREF) Total transformed score

Total score for each of the 5 subscale domains:

Overall Functioning Physical Capacity Psychological Social Relationships Environment
18 weeks
Neuropsychological Status
기간: 6 Weeks
Neuropsychological Global Composite Score Average normative t-score of: [CVLT-2 sum trials 1-5, D-KEFS Verbal Fluency total score, Trail Making Test - part B only, WAIS-IV Processing Speed, Working, CVLT- 2 Trial 1, CVLT-2 Trial 2, CVLT- 2 Trial 3, CVLT-2 Trial 4, CVLT-2 Trial 5, CVLT-2 Total Trials 1-5, CVLT-2 Total Trials 1-5 (T-score), CVLT-2 List B, SDFR, SDCR, LDFR, LDCR, total perseverations,total intrusions CVLT-2 LD recognition hits CVLT-2 LD recognition FP errors Trails part A, Trails part B, Trails part A, Trails part B, WAIS-IV Processing Speed Index, WAIS-IV Symbol Search
6 Weeks
Neuropsychological Status
기간: 12 Weeks
Neuropsychological Global Composite Score Average normative t-score of: [CVLT-2 sum trials 1-5, D-KEFS Verbal Fluency total score, Trail Making Test - part B only, WAIS-IV Processing Speed, Working, CVLT- 2 Trial 1, CVLT-2 Trial 2, CVLT- 2 Trial 3, CVLT-2 Trial 4, CVLT-2 Trial 5, CVLT-2 Total Trials 1-5, CVLT-2 Total Trials 1-5 (T-score), CVLT-2 List B, SDFR, SDCR, LDFR, LDCR, total perseverations,total intrusions CVLT-2 LD recognition hits CVLT-2 LD recognition FP errors Trails part A, Trails part B, Trails part A, Trails part B, WAIS-IV Processing Speed Index, WAIS-IV Symbol Search
12 Weeks
Neuropsychological Status
기간: 18 Weeks
Neuropsychological Global Composite Score Average normative t-score of: [CVLT-2 sum trials 1-5, D-KEFS Verbal Fluency total score, Trail Making Test - part B only, WAIS-IV Processing Speed, Working, CVLT- 2 Trial 1, CVLT-2 Trial 2, CVLT- 2 Trial 3, CVLT-2 Trial 4, CVLT-2 Trial 5, CVLT-2 Total Trials 1-5, CVLT-2 Total Trials 1-5 (T-score), CVLT-2 List B, SDFR, SDCR, LDFR, LDCR, total perseverations,total intrusions CVLT-2 LD recognition hits CVLT-2 LD recognition FP errors Trails part A, Trails part B, Trails part A, Trails part B, WAIS-IV Processing Speed Index, WAIS-IV Symbol Search
18 Weeks
Self Reported Alcohol Use Behaviors
기간: 6 weeks
Alcohol Use Disorders Identification Test (AUDIT) Summary Socre; 10 individual items
6 weeks
Self Reported Alcohol Use Behaviors
기간: 12 weeks
Alcohol Use Disorders Identification Test (AUDIT) Summary Socre; 10 individual items
12 weeks
Self Reported Alcohol Use Behaviors
기간: 18 weeks
Alcohol Use Disorders Identification Test (AUDIT) Summary Socre; 10 individual items
18 weeks
Post-Traumatic Stress Symptomatology
기간: 6 weeks
Post-Traumatic Stress Checklist-Military Form (PCL-M) Total Raw Socre 17 items
6 weeks
Post-Traumatic Stress Symptomatology
기간: Baseline
Post-Traumatic Stress Checkilist-Military Form (PCL-M) Total Raw Socre 17 items
Baseline
Post-Traumatic Stress Symptomatology
기간: 12 Weeks
Post-Traumatic Stress Checklist-Military Form (PCL-M) Total Raw Socre 17 items
12 Weeks
Self Reported Headache Disability
기간: 6 weeks
Headache Impact Test-6 (HIT-6) Total Weighted Score
6 weeks
Self Reported Headache Disability
기간: 12 weeks
Headache Impact Test-6 (HIT-6) Total Weighted Score
12 weeks
Self Reported Headache Disability
기간: 18 Weeks
Headache Impact Test-6 (HIT-6) Total Weighted Score
18 Weeks
Health Related (Cognition) Locus of Control
기간: 6 weeks
Multidimensional Health Locus of Control Scale (MHLCS-Form C) Internal subscale-total raw Chance subscale-total raw Powerful others subscale-total raw Doctors subscale-total raw Other people subscale-total raw
6 weeks
Health Related (Cognition) Locus of Control
기간: 12 weeks
Multidimensional Health Locus of Control Scale (MHLCS-Form C) Internal subscale-total raw Chance subscale-total raw Powerful others subscale-total raw Doctors subscale-total raw Other people subscale-total raw
12 weeks
Health Related (Cognition) Locus of Control
기간: 18 weeks
Multidimensional Health Locus of Control Scale (MHLCS-Form C) Internal subscale-total raw Chance subscale-total raw Powerful others subscale-total raw Doctors subscale-total raw Other people subscale-total raw
18 weeks
Perceived Self-Efficacy (Cognition)
기간: 6 weeks
Self-Efficacy for Symptom Management Scale SEsx total SEsocial subscale SEemotional subscale SEcognitvie subscale 13 individual items
6 weeks
Perceived Self-Efficacy (Cognition)
기간: 12 weeks
Self-Efficacy for Symptom Management Scale SEsx total SEsocial subscale SEemotional subscale SEcognitvie subscale 13 individual items
12 weeks
Perceived Self-Efficacy (Cognition)
기간: 18 weeks
Self-Efficacy for Symptom Management Scale SEsx total SEsocial subscale SEemotional subscale SEcognitvie subscale 13 individual items
18 weeks
Attribution of Cognitive Symptoms
기간: 6 weeks
Cognitive Symptom Attribution Scale 7 individual items
6 weeks
Attribution of Cognitive Symptoms
기간: 12 weeks
Cognitive Symptom Attribution Scale 7 individual items
12 weeks
Attribution of Cognitive Symptoms
기간: 18 weeks
Cognitive Symptom Attribution Scale 7 individual items
18 weeks
Therapist-Rated Patient Engagement in Treatment
기간: Week 1 of Treatment
Rehabilitation Intensity of Therapy Scale (RITS) Weekly average rating (weeks 1-6)
Week 1 of Treatment
Therapist-Rated Patient Engagement in Treatment
기간: Week 2 of treatment
Rehabilitation Intensity of Therapy Scale (RITS) Weekly average rating (weeks 1-6)
Week 2 of treatment
Therapist-Rated Patient Engagement in Treatment
기간: Week 3 of treatment
Rehabilitation Intensity of Therapy Scale (RITS) Weekly average rating (weeks 1-6)
Week 3 of treatment
Therapist-Rated Patient Engagement in Treatment
기간: Week 4 of treatment
Rehabilitation Intensity of Therapy Scale (RITS) Weekly average rating (weeks 1-6)
Week 4 of treatment
Therapist-Rated Patient Engagement in Treatment
기간: Week 5 of treatment
Rehabilitation Intensity of Therapy Scale (RITS) Weekly average rating (weeks 1-6)
Week 5 of treatment

공동 작업자 및 조사자

여기에서 이 연구와 관련된 사람과 조직을 찾을 수 있습니다.

스폰서

Brooke Army Medical Center

협력자

Henry M. Jackson Foundation for the Advancement of Military Medicine
The Defense and Veterans Brain Injury Center

수사관

  • 수석 연구원: Amy O Bowles, MD, BAMC

간행물 및 유용한 링크

연구에 대한 정보 입력을 담당하는 사람이 자발적으로 이러한 간행물을 제공합니다. 이것은 연구와 관련된 모든 것에 관한 것일 수 있습니다.

일반 간행물

유용한 링크

연구 기록 날짜

이 날짜는 ClinicalTrials.gov에 대한 연구 기록 및 요약 결과 제출의 진행 상황을 추적합니다. 연구 기록 및 보고된 결과는 공개 웹사이트에 게시되기 전에 특정 품질 관리 기준을 충족하는지 확인하기 위해 국립 의학 도서관(NLM)에서 검토합니다.

연구 주요 날짜

연구 시작

2011년 6월 1일

기본 완료 (실제)

2014년 6월 1일

연구 완료 (실제)

2014년 8월 1일

연구 등록 날짜

최초 제출

2011년 4월 15일

QC 기준을 충족하는 최초 제출

2011년 4월 20일

처음 게시됨 (추정)

2011년 4월 21일

연구 기록 업데이트

마지막 업데이트 게시됨 (추정)

2015년 2월 9일

QC 기준을 충족하는 마지막 업데이트 제출

2015년 2월 6일

마지막으로 확인됨

2015년 2월 1일

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추가 관련 MeSH 약관

기타 연구 ID 번호

  • C.2010.199

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