The Acute Effects of Controlled Breathing Exercises and Music Therapy on the Autonomic Nervous System in Anxious Individuals
2026년 8월 17일 업데이트: Okan Sahin, Istanbul Health and Technology University
The Acute Effects of Controlled Breathing Exercises and Music Therapy on the Autonomic Nervous System in Anxious Individuals: A Randomized Controlled Study
This project aims to investigate the acute effects of controlled breathing exercises and music therapy on parasympathetic nervous system activation and increased heart rate variability in anxious individuals.
연구 개요
상태
완전한
상세 설명
The main objective of our project is to reduce the suppressive effect of stress on the parasympathetic nervous system and, accordingly, to increase heart rate variability in individuals with anxiety through controlled breathing exercises and music therapy applications. For this purpose, individuals aged between 18 and 40 years who have moderate anxiety levels according to the State-Trait Anxiety Inventory, who have not previously been diagnosed with any cardiovascular, respiratory, neurological, or psychiatric diseases, and who have not smoked for at least the past 6 months will be included in the study.
The individuals included in the study will be randomly assigned into three groups: a control group, a controlled breathing exercise group, and a music-supported breathing exercise group. At the baseline assessment, the State-Trait Anxiety Inventory will be used to determine the anxiety levels of all participants and to ensure group homogenization. In addition to determining anxiety levels at baseline, heart rate variability, blood pressure, heart rate, and oxygen saturation will be assessed in all groups.
No intervention will be applied to the control group; only assessments will be conducted. A single-session exercise protocol lasting 20 minutes will be applied to the breathing exercise group and the music-supported breathing exercise group. Heart rate variability will be measured using the Polar H9 device and Elite HRV software. Blood pressure and heart rate measurements will be performed using a digital blood pressure monitor. Oxygen saturation will be determined using a fingertip pulse oximeter.
The heart rate variability, blood pressure, heart rate, and oxygen saturation assessments performed at baseline will be repeated at the 0th, 10th, and 20th minutes after the completion of the exercise in the intervention groups. In the control group, participants will be asked to remain seated for 20 minutes, and following the completion of this period, the measurements performed at baseline will be repeated at the 0th, 10th, and 20th minutes. Thus, the final evaluation will be completed, and the obtained data will be analyzed.
연구 유형
중재적
등록 (실제)
30
단계
- 해당 없음
연락처 및 위치
이 섹션에서는 연구를 수행하는 사람들의 연락처 정보와 이 연구가 수행되는 장소에 대한 정보를 제공합니다.
연구 장소
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Beyoğlu
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Istanbul, Beyoğlu, 터키 (Türkiye), 34421
- Istanbul Health and Technology University
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참여기준
연구원은 적격성 기준이라는 특정 설명에 맞는 사람을 찾습니다. 이러한 기준의 몇 가지 예는 개인의 일반적인 건강 상태 또는 이전 치료입니다.
자격 기준
공부할 수 있는 나이
- 성인
건강한 자원 봉사자를 받아들입니다
아니
설명
Inclusion Criteria:
- Volunteer to participate in the study
- Not having a prior diagnosis of cardiovascular, respiratory, or neurological/psychiatric disease
- Not having a history of regular arrhythmias, pacemakers, or severe hypertension
- Not having smoked for at least 6 months
- Not having engaged in strenuous exercise in the last 24 hours
- Not having consumed caffeine/energy drinks within 6-8 hours prior to the intervention
- Being between 18 and 40 years of age
- Having a moderate level of anxiety according to the State-Trait Anxiety Scale
- Participants must be literate and have at least a high school diploma.
Exclusion Criteria:
- Having an active or chronic illness
- Experiencing cooperation problems
- Regular use of psychiatric medication (antidepressants, anxiolytics, etc.)
- Use of medications that affect heart rate, such as beta-blockers
- Auditory dysfunction (to the point of being unable to hear music)
- Individuals who are highly trained (very experienced) in breathing exercises or meditation
공부 계획
이 섹션에서는 연구 설계 방법과 연구가 측정하는 내용을 포함하여 연구 계획에 대한 세부 정보를 제공합니다.
연구는 어떻게 설계됩니까?
디자인 세부사항
- 주 목적: 치료
- 할당: 무작위
- 중재 모델: 병렬 할당
- 마스킹: 하나의
무기와 개입
참가자 그룹 / 팔 |
개입 / 치료 |
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간섭 없음: Control Group(CG)
The control group will not receive any intervention.
Participants in this group will be asked to sit comfortably in a chair for a single 20-minute session.
Individuals will be provided with an environment where disturbing factors (sound, light) are prevented.
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실험적: Controlled Breathing Exercises Group (CBE)
Controlled breathing exercises will include resonant breathing, nadi shodhana, bhramari pranayama, and physiological sighing exercises.
Controlled breathing exercises will be performed in a single session lasting a total of 20 minutes.
Individuals will be provided with an environment where disturbing factors (sound, light) are prevented.
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Controlled breathing exercises include Resonance Breathing Exercises, Nadi Shodhana Pranayama, Bhramari Pranayama, and physiological sighing exercises.
The controlled breathing exercise group will receive these exercises in a single 20-minute session.
Resonance breathing will be practiced for 5 minutes at a rate of 6 breaths per minute.
During the intervention, patients will receive 2 sets of Nadi Shodhana Pranayama consisting of 8 breathing cycles, with a 2-minute rest period between sets.
The session will also include 2 sets of Bhramari Pranayama consisting of 8 breathing cycles at a low breathing rate, with a 1-minute rest period between sets.
The physiological sighing exercise involves an initial inhalation phase lasting 1 second, a second inhalation phase lasting 0.25 seconds, and an exhalation phase lasting 2 seconds, and is repeated for 5 minutes.
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실험적: Music-Assisted Breathing Group (MAB)
The music-assisted breathing exercise will perform the same breathing exercises (resonant breathing, nadi shodhana, bhramari pranayama, and physiological sighing) along with music.
Individuals will be provided with an environment where disturbing factors (sound, light) are prevented.
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The music-assisted breathing exercise will perform the same breathing exercises (resonant breathing, nadi shodhana, bhramari pranayama, and physiological sighing) along with music.
Music-assisted breathing exercise will be performed in a single session lasting a total of 20 minutes.
Music 1 (250-1000 Hz) and Music 2 (1000-16000 Hz) will be used at specific frequencies.
A slow, rhythmically consistent, vocalless basic melody will be selected within these frequency ranges.
The volume levels of all tracks will be kept constant.
The music will be played through stereo headphones.
Participants will listen to Music 1 (250-1000 Hz) for 10 minutes and Music 2 (1000-16000 Hz) for another 10 minutes.
Individuals will be provided with an environment where disturbing factors (sound, light) are prevented.
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연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
측정값 설명 |
기간 |
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Autonomic Nervous System Assessment
기간: Baseline, and at 0, 10, and 20 minutes after the 20-minute exercise session.
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To assess the autonomic nervous system, heart rate variability will be evaluated.
A Polar H9 heart rate sensor chest strap and Elite HRV software will be used to measure analytical heart rate variability.
During the assessment, the participant will be in a seated position in a chair, the Polar system chest strap will be placed directly over the sternum, and ultrasound gel will be used to increase the conductivity of the sensor.
This method has validity with electrocardiogram.
Heart rate variability parameters such as RMSSD, PNN50, and LF/HF will be measured.
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Baseline, and at 0, 10, and 20 minutes after the 20-minute exercise session.
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Pulse Measurement
기간: Baseline, and at 0, 10, and 20 minutes after the 20-minute exercise session.
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Pulse measurements will be performed using an Omron brand digital blood pressure monitor.
Individuals will be rested for at least 5 minutes before the measurement to ensure relaxation for an accurate reading.
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Baseline, and at 0, 10, and 20 minutes after the 20-minute exercise session.
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Blood Pressure Measurement
기간: Baseline, and at 0, 10, and 20 minutes after the 20-minute exercise session.
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Blood pressure measurements will be performed using an Omron brand digital blood pressure monitor.
Individuals will be rested for at least 5 minutes before the measurement to ensure relaxation for an accurate reading.
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Baseline, and at 0, 10, and 20 minutes after the 20-minute exercise session.
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2차 결과 측정
결과 측정 |
측정값 설명 |
기간 |
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Oxygen Saturation
기간: Baseline, and at 0, 10, and 20 minutes after the 20-minute exercise session.
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Pulse oximetry is a non-invasive, painless, and reliable method used to measure oxygen saturation (SpO2) in arterial blood.
Oxygen saturation measurement will be performed with a finger-type pulse oximeter device.
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Baseline, and at 0, 10, and 20 minutes after the 20-minute exercise session.
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기타 결과 측정
결과 측정 |
측정값 설명 |
기간 |
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State-Trait Anxiety Scale
기간: Baseline
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To determine the anxiety level of all participants and to ensure group homogeneity, the State-Trait Anxiety Scale will be used.
Individuals with moderate anxiety according to the State-Trait Anxiety Scale will be included in the study.
This scale aims to assess the intensity of the emotions or behaviors expressed in the items on the scale.
Theoretically, scores on this scale can range from 20 to 80.
A higher score indicates a high level of anxiety, while a lower score indicates a low level of anxiety.
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Baseline
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공동 작업자 및 조사자
여기에서 이 연구와 관련된 사람과 조직을 찾을 수 있습니다.
수사관
- 연구 책임자: Okan Şahin, PT, PhD, Istanbul Health and Technology University
간행물 및 유용한 링크
연구에 대한 정보 입력을 담당하는 사람이 자발적으로 이러한 간행물을 제공합니다. 이것은 연구와 관련된 모든 것에 관한 것일 수 있습니다.
일반 간행물
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- Parizek D, Visnovcova N, Hamza Sladicekova K, Veternik M, Jakus J, Jakusova J, Visnovcova Z, Ferencova N, Tonhajzerova I. Effect of Selected Music Soundtracks on Cardiac Vagal Control and Complexity Assessed by Heart Rate Variability. Physiol Res. 2023 Nov 28;72(5):587-596. doi: 10.33549/physiolres.935114.
- Balban MY, Neri E, Kogon MM, Weed L, Nouriani B, Jo B, Holl G, Zeitzer JM, Spiegel D, Huberman AD. Brief structured respiration practices enhance mood and reduce physiological arousal. Cell Rep Med. 2023 Jan 17;4(1):100895. doi: 10.1016/j.xcrm.2022.100895. Epub 2023 Jan 10.
- Naci B, Demir R, Onder OO, Sinan UY, Kucukoglu MS. Effects of Adding Respiratory Training to Osteopathic Manipulative Treatment on Exhaled Nitric Oxide Level and Cardiopulmonary Function in Patients With Pulmonary Arterial Hypertension. Am J Cardiol. 2022 Jan 1;162:184-190. doi: 10.1016/j.amjcard.2021.09.023. Epub 2021 Oct 24.
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- Chaitanya S, Datta A, Bhandari B, Sharma VK. Effect of Resonance Breathing on Heart Rate Variability and Cognitive Functions in Young Adults: A Randomised Controlled Study. Cureus. 2022 Feb 13;14(2):e22187. doi: 10.7759/cureus.22187. eCollection 2022 Feb.
- Öner, N. Ve Le Compte, A. (1998). Süreksiz Durumluk/Sürekli Kaygı Envanteri El Kitabı (2. baskı). İstanbul: Boğaziçi Üniversitesi Yayınevi.
- Hatik SH, Arslan M, Demirbilek O, Ozden AV. The effect of transcutaneous auricular vagus nerve stimulation on cycling ergometry and recovery in healthy young individuals. Brain Behav. 2023 Dec;13(12):e3332. doi: 10.1002/brb3.3332. Epub 2023 Nov 16.
- Latha, R., Tamilselvan, K., Susiganeshkumar, E., & Sairaman, H. (2015). Effect of classical music on heart rate variability between genders. International Journal of Biomedical Research, 6(03), 192-195.
- Brown RP, Gerbarg PL, Muench F. Breathing practices for treatment of psychiatric and stress-related medical conditions. Psychiatr Clin North Am. 2013 Mar;36(1):121-40. doi: 10.1016/j.psc.2013.01.001.
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연구 기록 날짜
이 날짜는 ClinicalTrials.gov에 대한 연구 기록 및 요약 결과 제출의 진행 상황을 추적합니다. 연구 기록 및 보고된 결과는 공개 웹사이트에 게시되기 전에 특정 품질 관리 기준을 충족하는지 확인하기 위해 국립 의학 도서관(NLM)에서 검토합니다.
연구 주요 날짜
연구 시작 (실제)
2026년 5월 2일
기본 완료 (실제)
2026년 8월 14일
연구 완료 (실제)
2026년 8월 15일
연구 등록 날짜
최초 제출
2026년 5월 10일
QC 기준을 충족하는 최초 제출
2026년 5월 17일
처음 게시됨 (실제)
2026년 5월 19일
연구 기록 업데이트
마지막 업데이트 게시됨 (실제)
2026년 8월 19일
QC 기준을 충족하는 마지막 업데이트 제출
2026년 8월 17일
마지막으로 확인됨
2026년 4월 1일
추가 정보
이 연구와 관련된 용어
기타 연구 ID 번호
- OEZBP-2026
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