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Large Language Models for Dental Radiology Report Generation From Structured Textual Data (DENT-LLM)

Evaluation of Large Language Models for Transforming Structured Dental Radiology Data Into Narrative Radiology Reports

The purpose of this observational methodological study is to evaluate whether large language models can transform structured dental radiology data into clear narrative radiology reports. Large language models are computer programs that can generate text from information provided to them. In this study, the input will consist of organized dental radiology findings, such as chart-style or diagram-based information about teeth and surrounding structures.

Dental radiology reports are used by dentists and other health care providers to understand imaging findings and support clinical documentation. Preparing narrative reports may be time-consuming, and the wording of reports may vary between clinicians. This study will examine whether language-model-assisted report generation can produce reports that are complete, accurate, understandable, and clinically useful.

The study will compare reports generated with support from large language models with traditionally prepared reports. Researchers will also assess how the wording of the prompt and selected model parameters influence report quality. In addition, the study will analyze errors and safety risks in generated reports and evaluate whether such a system could be practical in a dental radiology workflow. The language model will not make treatment decisions, and generated reports will be used for research evaluation only.

연구 개요

상세 설명

This study is designed to evaluate the use of large language models for converting structured dental radiology data into narrative radiology reports. The project focuses on the quality, safety, and practical usability of language-model-assisted report generation in dental radiology.

Structured dental radiology data will be used as the input for the language model. These data may include organized findings recorded in a diagram, chart, or predefined structured format. The model will be asked to transform this structured information into a narrative report resembling a conventional dental radiology description. The study does not evaluate the model as an autonomous diagnostic system. The model will not independently interpret radiographic images, establish a diagnosis, or recommend treatment. Its role is limited to generating narrative text from already structured radiological information.

The study will include several related analyses. First, the investigators will assess whether a large language model can reliably transform structured dental radiology findings into a narrative report. Generated reports will be evaluated for completeness, factual consistency with the source data, clarity, terminology, and clinical readability.

Second, the study will examine how prompt construction and model parameters affect the quality of the generated reports. Different prompt formats and selected generation settings may be compared to identify configurations associated with higher report quality and fewer errors.

Third, reports generated with model assistance will be compared with traditionally prepared narrative reports. The comparison may include blinded assessment by qualified evaluators, who will judge report quality without knowing whether a report was generated traditionally or with model support.

Fourth, the study will include an error and safety analysis. Errors may include omitted findings, added findings not present in the source data, incorrect tooth numbering, inconsistent terminology, misleading wording, or statements that could affect clinical interpretation. The purpose of this analysis is to identify types of errors that may occur when large language models are used for this task and to assess their potential clinical relevance.

Finally, the study will assess the potential implementation usefulness of the report-generation workflow. This may include evaluation of usability, perceived time savings, acceptability to users, clarity of generated text, and the need for human review before clinical use.

All generated reports will require expert evaluation in the study setting. The system is intended to support documentation research and workflow assessment, not to replace professional judgment. The study will provide evidence on whether language-model-assisted transformation of structured dental radiology data into narrative reports is feasible, accurate, safe, and potentially useful for future clinical documentation workflows.

연구 유형

관찰

등록 (추정된)

100

연락처 및 위치

이 섹션에서는 연구를 수행하는 사람들의 연락처 정보와 이 연구가 수행되는 장소에 대한 정보를 제공합니다.

연구 연락처

연구 장소

    • Świętokrzyskie Voivodeship
      • Kielce, Świętokrzyskie Voivodeship, 폴란드, 25-375
        • Department of Maxillofacial Surgery
        • 연락하다:

참여기준

연구원은 적격성 기준이라는 특정 설명에 맞는 사람을 찾습니다. 이러한 기준의 몇 가지 예는 개인의 일반적인 건강 상태 또는 이전 치료입니다.

자격 기준

공부할 수 있는 나이

  • 성인
  • 고령자

건강한 자원 봉사자를 받아들입니다

아니

샘플링 방법

비확률 샘플

연구 인구

The study population will consist of dental radiology records from patients admitted to the radiology department in Kielce, a city in southern Poland with approximately 200,000 inhabitants. Eligible records will include dental X-ray examinations performed on the basis of a written referral from a dentist or physician, including examinations performed for screening, diagnostic, or treatment-planning purposes. The study will include records from patients with permanent dentition after completion of exfoliation, provided that structured dental radiology data are available for transformation into narrative radiology reports.

설명

Inclusion Criteria:

  • Dental radiology records based on dental X-ray examination performed on the basis of a written referral from a dentist or physician
  • Dental X-ray examinations performed for screening, diagnostic, or treatment-planning purposes
  • Records from patients with permanent dentition after completion of exfoliation

Exclusion Criteria:

  • Records from patients with mixed dentition before completion of exfoliation
  • Records with incomplete, ambiguous, or internally inconsistent structured dental radiology data preventing reliable report generation
  • Records with missing information required for evaluation of the generated report
  • Duplicate records from the same radiographic examination
  • Records in which anonymization or pseudonymization cannot be ensured

공부 계획

이 섹션에서는 연구 설계 방법과 연구가 측정하는 내용을 포함하여 연구 계획에 대한 세부 정보를 제공합니다.

연구는 어떻게 설계됩니까?

디자인 세부사항

코호트 및 개입

그룹/코호트
개입 / 치료
Dental radiology records
Structured dental radiology records used to evaluate large language model-assisted generation of narrative dental radiology reports.
Structured dental radiology data will be processed using a large language model to generate narrative dental radiology reports. The model will transform predefined structured findings into report text for research evaluation. The model will not independently interpret radiographic images, make clinical diagnoses, recommend treatment, or replace professional review. Generated reports will be assessed for completeness, factual consistency with the source data, clarity, terminology, errors, safety, and potential workflow usefulness.

연구는 무엇을 측정합니까?

주요 결과 측정

결과 측정
측정값 설명
기간
Factual consistency of large language model-generated dental radiology reports with structured source data
기간: At the time of report generation and expert evaluation, up to 12 months
Factual consistency will be assessed by comparing each large language model-generated narrative dental radiology report with the corresponding structured dental radiology source data. Expert evaluators will assess whether the generated report accurately reflects the source data without adding findings, omitting findings, changing tooth numbering, or altering the clinical meaning of the structured findings. The outcome will be reported as the proportion of generated reports without clinically relevant factual inconsistency and/or as the number and type of factual inconsistencies per report.
At the time of report generation and expert evaluation, up to 12 months

2차 결과 측정

결과 측정
측정값 설명
기간
Completeness of large language model-generated dental radiology reports
기간: At the time of report generation and expert evaluation, up to 12 months
Completeness will be assessed by determining whether all predefined findings present in the structured dental radiology source data are included in the generated narrative report. The outcome will be reported as the proportion of required findings correctly included in each report and/or the proportion of complete reports.
At the time of report generation and expert evaluation, up to 12 months
Error rate and error categories in large language model-generated dental radiology reports
기간: At the time of report generation and expert evaluation, up to 12 months
Generated reports will be reviewed for predefined error categories, including omitted findings, added findings not present in the source data, incorrect tooth numbering, inconsistent terminology, ambiguous wording, and statements with potential clinical relevance. The outcome will be reported as the number and frequency of each error category per report and across all generated reports.
At the time of report generation and expert evaluation, up to 12 months
Overall quality score of dental radiology reports
기간: At the time of blinded or non-blinded expert evaluation, up to 12 months
Overall report quality will be assessed by qualified evaluators using a predefined rating scale that may include clarity, readability, terminology, organization, completeness, and clinical usefulness. The outcome will be reported as the mean or median quality score for generated reports and, where applicable, for traditionally prepared reports.
At the time of blinded or non-blinded expert evaluation, up to 12 months
Difference in expert-rated quality between traditional and large language model-assisted dental radiology reports
기간: At the time of comparative expert evaluation, up to 12 months
Traditional narrative dental radiology reports and large language model-assisted reports will be compared using expert assessment. Evaluators may be blinded to the report-generation method where feasible. The outcome will be reported as the difference in predefined quality scores between traditional and model-assisted reports.
At the time of comparative expert evaluation, up to 12 months
Effect of prompt design and model parameters on generated report quality
기간: At the time of prompt and parameter comparison, up to 12 months
The quality of reports generated using different prompt formats and selected model-generation parameters will be compared. Outcomes may include factual consistency, completeness, error rate, and overall quality score. The analysis will identify prompt and parameter configurations associated with higher report quality and fewer errors.
At the time of prompt and parameter comparison, up to 12 months
Usability of the large language model-assisted dental radiology reporting workflow
기간: At the time of usability assessment, up to 12 months
Usability will be assessed among users involved in evaluating or testing the model-assisted reporting workflow. Measures may include perceived usefulness, ease of use, clarity of generated reports, perceived need for editing, and potential workflow acceptability. The outcome will be reported using predefined questionnaire items or usability ratings.
At the time of usability assessment, up to 12 months

공동 작업자 및 조사자

여기에서 이 연구와 관련된 사람과 조직을 찾을 수 있습니다.

연구 기록 날짜

이 날짜는 ClinicalTrials.gov에 대한 연구 기록 및 요약 결과 제출의 진행 상황을 추적합니다. 연구 기록 및 보고된 결과는 공개 웹사이트에 게시되기 전에 특정 품질 관리 기준을 충족하는지 확인하기 위해 국립 의학 도서관(NLM)에서 검토합니다.

연구 주요 날짜

연구 시작 (추정된)

2026년 6월 29일

기본 완료 (추정된)

2026년 7월 26일

연구 완료 (추정된)

2026년 7월 26일

연구 등록 날짜

최초 제출

2026년 6월 24일

QC 기준을 충족하는 최초 제출

2026년 6월 24일

처음 게시됨 (실제)

2026년 6월 30일

연구 기록 업데이트

마지막 업데이트 게시됨 (실제)

2026년 6월 30일

QC 기준을 충족하는 마지막 업데이트 제출

2026년 6월 24일

마지막으로 확인됨

2026년 6월 1일

추가 정보

이 연구와 관련된 용어

기타 연구 ID 번호

  • CT/2026/1

개별 참가자 데이터(IPD) 계획

개별 참가자 데이터(IPD)를 공유할 계획입니까?

예

IPD 계획 설명

The investigators plan to share a de-identified structured dataset containing symbolic dental pathology notation derived from panoramic dental radiographs, for example tooth-level coded entries such as "16DR", "15M", or "14C". The shared dataset will not include radiographic images, names, dates of birth, personal identifiers, or other directly identifying information. Data sharing will be performed in accordance with the approval and conditions specified by the Bioethics Committee. The dataset will be shared to support transparency, reproducibility, and independent verification of the large language model-assisted report generation task.

IPD 공유 기간

Beginning at the time of publication of the main study results and available for at least 5 years.

IPD 공유 액세스 기준

The de-identified structured dental pathology notation dataset will be made available as supplementary material accompanying the publication of the main study results or through a scientific data repository. The shared data will not include radiographic images, direct identifiers, dates of birth, names, or other directly identifying information.

IPD 공유 지원 정보 유형

  • 연구_프로토콜
  • 수액
  • ANALYTIC_CODE

약물 및 장치 정보, 연구 문서

미국 FDA 규제 의약품 연구

아니

미국 FDA 규제 기기 제품 연구

아니

이 정보는 변경 없이 clinicaltrials.gov 웹사이트에서 직접 가져온 것입니다. 귀하의 연구 세부 정보를 변경, 제거 또는 업데이트하도록 요청하는 경우 register@clinicaltrials.gov. 문의하십시오. 변경 사항이 clinicaltrials.gov에 구현되는 즉시 저희 웹사이트에도 자동으로 업데이트됩니다. .

구독하다