The Effect of Calcium on Fecal Fat and Energy Excretion
研究概览
详细说明
Several reports have found inverse associations between calcium intake and body weight. Few intervention studies have shown that a high calcium diet resulted in a greater body weight loss than a low calcium diet. The mechanism is not clear, but one possible explanation is reduced absorption of fat in the gut, due to formation of insoluble calcium fatty acid soaps or binding of bile acids which impairs the formation of micelles.
The aim of this study is to examined if a high calcium intake from dairy products, in diets high or normal in fat content, have an effect on fecal energy and fat excretion, concentrations of substrates involved in energy metabolism and blood pressure.
研究类型
注册 (预期的)
阶段
- 不适用
联系人和位置
学习联系方式
- 姓名：Arne Astrup, prof. MD
- 电话号码：+45 3533 2476
- 邮箱：ast@life.ku.dk
学习地点
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Frederiksberg、丹麦、1958
- 招聘中
- Dept. of Human Nutrition, Faculty of Life Sciences, University of Copenhagen
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接触：
- Arne Astrup, prof. MD
- 电话号码：+45 3533 2476
- 邮箱：ast@life.ku.dk
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接触：
- Janne K Lorenzen, PhD student
- 电话号码：+45 3533 3632
- 邮箱：jakh@life.ku.dk
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首席研究员：
- Janne K Lorenzen, PhD student
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- healthy meals
- BMI 24-31 kg/m2
- age between 18-50 years
Exclusion Criteria:
- donation of blood 6 months before and under the study
- milk allergy, diabetes, hypertension, hyperlipidemia, cronic infectious disease
- use of dietary supplements 3 months before and under the study
- smoking
- elite athletes
- use of medication
学习计划
研究是如何设计的？
设计细节
- 主要用途：基础科学
- 分配：随机化
- 介入模型：交叉作业
- 屏蔽：无（打开标签）
武器和干预
参与者组/臂 |
干预/治疗 |
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其他：1
Diet with high content of calcium and high content of fat
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Diets with different content of calcium and fat
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其他：2
Diet with low content of calcium and high content of fat
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Diets with different content of calcium and fat
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其他：3
Diet with high content of calcium and normal content of fat
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Diets with different content of calcium and fat
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其他：4
Diet with low content of calcium and normal content of fat
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Diets with different content of calcium and fat
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其他：5
Diet with high content of calcium fra supplement and high content of fat
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Diets with different content of calcium and fat
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研究衡量的是什么？
主要结果指标
结果测量 |
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Fecal fat excretion, fecal energy excretion, calcium excretion, cholesterol
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次要结果测量
结果测量 |
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Vitamin D, changes in lipolyse
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合作者和调查者
合作者
调查人员
- 首席研究员：Janne K Lorenzen, PhD student、Dept. of Human Nutrition, Faculty of Life Sciences, Univerity of Copenhagen
研究记录日期
研究主要日期
学习开始
研究完成 (预期的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
其他研究编号
- H-KF-01-144/02
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.
Dairy calcium的临床试验
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Aristotle University Of ThessalonikiHellenic Society of Hypertension完全的