Prospective Single-center Study Evaluating the Central Blood Pressure in Renal Transplantation (PACT)
The renal transplant patient is at high cardiovascular risk compared to the general population. The cardiovascular mortality represents one of the most important causes of late graft loss. Cardiovascular risk prediction tools applied to the general population, however, are caught failing on the population of kidney transplant and tend to underestimate the actual risk.
Central blood pressure is the pressure imposed at large artery (aorta, carotid) and is directly related to the target organ (heart, kidney, brain). Central blood pressure could be a cardiovascular risk factor more robust and powerful than brachial blood pressure.
Central blood pressure may in part explain the increased risk of cardiovascular disease in the population of kidney transplant patients. A cohort of 250 kidney transplant patients will be constituted with a measure of concomitant central hemodynamic monitoring to the annual review will be conducted. The main objective of this study is to describe the central blood pressure measured by oscillometric method in renal transplanted population.
研究概览
研究类型
注册 (实际的)
阶段
- 不适用
联系人和位置
学习地点
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Saint-etienne、法国、42000
- CHU de Saint-Etienne
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- Major Patient
- Renal transplant patient
Exclusion Criteria:
- Minor patient
学习计划
研究是如何设计的?
设计细节
- 主要用途:诊断
- 分配:不适用
- 介入模型:单组作业
- 屏蔽:无(打开标签)
武器和干预
参与者组/臂 |
干预/治疗 |
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实验性的:renal transplant patient
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Central blood pressure recorded in the non-fistula arm using a validated oscillometric device (Arteriograph®, Medexpert).
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研究衡量的是什么?
主要结果指标
结果测量 |
大体时间 |
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central blood pressure
大体时间:Baseline
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Baseline
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合作者和调查者
调查人员
- 首席研究员:Christophe MARIAT, MD PhD、CHU de Saint-Etienne
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
此信息直接从 clinicaltrials.gov 网站检索,没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求,请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改,我们的网站上也会自动更新.
oscillometric device (Arteriograph®, Medexpert)的临床试验
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University Hospital, Basel, SwitzerlandClinical Trial Unit, University Hospital Basel, Switzerland完全的
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Instituto Valenciano de Infertilidad, IVI VALENCIAIVI Madrid招聘中
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Federal University of AmazonasCoordination for the Improvement of Higher Education Personnel完全的