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Ai Chi-Based Rehabilitation for Peripheral Unilateral Vestibular Dysfunction (AICHI-VR)

2026年5月4日 更新者:Yaren Çelik、Gaziosmanpasa Research and Education Hospital

Contribution of an Ai Chi-Based Rehabilitation Program in Patients With Peripheral Unilateral Vestibular Dysfunction: A Randomized Prospective Single-Blind Study

This study aims to evaluate the effects of an Ai Chi-based rehabilitation program on balance, dizziness severity, and quality of life in patients with unilateral peripheral vestibular hypofunction. Participants will be randomly assigned to either a control group receiving standard home-based vestibular rehabilitation exercises or an intervention group receiving additional Ai Chi sessions. The intervention will be conducted over a 4-week period with a total of 10 sessions under the supervision of a certified therapist.

研究概览

详细说明

Unilateral peripheral vestibular hypofunction is a clinical condition characterized by reduced vestibular function due to inner ear or vestibular nerve pathology. It presents with symptoms such as dizziness, imbalance, visual instability, and impaired postural control, significantly affecting functional independence and quality of life. Diagnosis is typically established by the otorhinolaryngology clinic and supported by vestibular function tests such as videonystagmography (VNG) and video head impulse testing (vHIT).

Vestibular rehabilitation is an evidence-based therapeutic approach aimed at promoting central compensation through mechanisms of adaptation, substitution, and habituation. These mechanisms contribute to the improvement of vestibulo-ocular reflex function, postural stability, and overall functional performance.

Ai Chi is an aquatic exercise program derived from Tai Chi and Qi Gong principles, consisting of slow, continuous, and controlled movements coordinated with breathing. The aquatic environment provides unique therapeutic properties such as buoyancy, hydrostatic pressure, and viscosity, allowing safe movement, reducing fall risk, and enhancing proprioceptive and sensory input. These features may support multisensory integration and facilitate central compensation in patients with vestibular dysfunction.

Although aquatic therapy has been increasingly used in rehabilitation, there is limited evidence regarding the effectiveness of Ai Chi specifically in patients with unilateral peripheral vestibular hypofunction. To the best of our knowledge, no randomized controlled study has specifically evaluated the effects of Ai Chi in this patient population.

In this randomized controlled study, participants will be allocated into two groups. Both groups will receive a standardized home-based vestibular rehabilitation program. In addition, the intervention group will participate in supervised Ai Chi sessions conducted in an aquatic environment over a 4-week period, consisting of a total of 10 sessions. All sessions will be delivered by a certified therapist, and adherence will be monitored using exercise logs.

Assessments will be performed at baseline, immediately after the intervention, and during the follow-up period by a blinded evaluator. The findings of this study are expected to contribute to the development of alternative rehabilitation strategies and provide additional evidence for the management of patients with vestibular disorders.

研究类型

介入性

注册 (估计的)

38

阶段

  • 不适用

联系人和位置

本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。

学习联系方式

参与标准

研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

  • 成人
  • 年长者

接受健康志愿者

不

描述

Inclusion Criteria:

  • Age between 18 and 70 years
  • Diagnosis of unilateral peripheral vestibular hypofunction
  • Presence of dizziness symptoms for at least 3 months
  • Ability to participate in Ai Chi and aquatic exercise program
  • Berg Balance Scale score ≥21
  • Willingness to participate in the study

Exclusion Criteria:

  • Inability to complete assessment tests and questionnaires
  • Severe systemic disease that may interfere with exercise participation
  • Central vestibular disorders
  • Berg Balance Scale score ≤20
  • Severe visual or hearing impairment
  • Initiation or change of psychiatric medication within the last 3 weeks
  • Severe cardiopulmonary disease
  • Contraindications to hydrotherapy, including water phobia, behavioral disorders, dyspnea at rest, incontinence, known chlorine allergy, open wounds, acute systemic illness, epilepsy, tracheostomy, permanent drainage devices, immunodeficiency, or known neurological disorders

学习计划

本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。

研究是如何设计的?

设计细节

  • 主要用途:治疗
  • 分配:随机化
  • 介入模型:并行分配
  • 屏蔽:单身的

武器和干预

参与者组/臂
干预/治疗
实验性的:Ai Chi Group
Participants in this group will receive an Ai Chi-based aquatic exercise program in addition to standard home-based vestibular rehabilitation exercises. The Ai Chi program will be applied over 4 weeks with a total of 10 sessions under the supervision of a certified therapist.
Ai Chi-based exercise program is a structured aquatic therapy approach consisting of slow, continuous, and controlled movements combined with breathing techniques. The program will be conducted in a pool environment over 4 weeks, with a total of 10 sessions delivered as group sessions under the supervision of a certified therapist. The exercises are designed to enhance balance, postural control, proprioceptive input, and multisensory integration, thereby supporting central compensation in patients with vestibular dysfunction.
Participants will receive a structured home-based vestibular rehabilitation program including gaze stabilization, head movement, balance, and postural control exercises. The program aims to promote vestibulo-ocular reflex adaptation, improve postural stability, and reduce dizziness-related symptoms. Participants will be instructed to perform the exercises regularly, and adherence will be monitored using exercise logs.
有源比较器:Control Group
Participants in this group will receive standard home-based vestibular rehabilitation exercises without additional Ai Chi intervention.
Participants will receive a structured home-based vestibular rehabilitation program including gaze stabilization, head movement, balance, and postural control exercises. The program aims to promote vestibulo-ocular reflex adaptation, improve postural stability, and reduce dizziness-related symptoms. Participants will be instructed to perform the exercises regularly, and adherence will be monitored using exercise logs.

研究衡量的是什么?

主要结果指标

结果测量
措施说明
大体时间
Change in balance performance assessed by Berg Balance Scale
大体时间:Baseline, immediately after the 4-week intervention, and 2 months after the end of treatment
Change in balance performance will be assessed using the Berg Balance Scale (BBS). The BBS consists of 14 items scored from 0 to 4, with a total score ranging from 0 to 56. Higher scores indicate better balance performance. balance performance will be assessed using the Berg Balance Scale in participants receiving Ai Chi-based exercise program in addition to home-based vestibular rehabilitation, compared with participants receiving home-based vestibular rehabilitation alone.
Baseline, immediately after the 4-week intervention, and 2 months after the end of treatment

次要结果测量

结果测量
措施说明
大体时间
Change in dizziness-related disability will be assessed using the Dizziness Handicap Inventory (DHI). The DHI consists of 25 items with a total score ranging from 0 to 100. Higher scoredizziness-related disability assessed by Dizziness Handicap Inventory
大体时间:Baseline, immediately after the 4-week intervention, and 2 months after the end of treatment
Change in dizziness-related disability will be assessed using the Dizziness Handicap Inventory.
Baseline, immediately after the 4-week intervention, and 2 months after the end of treatment
Change in dizziness severity assessed by Vertigo Symptom Scale-Short Form
大体时间:Baseline, immediately after the 4-week intervention, and 2 months after the end of treatment
Change in vestibular symptoms will be assessed using the Vestibular Symptoms Scale (VSS). The VSS consists of 15 items evaluating the frequency of vestibular symptoms. Each item is scored from 0 to 4, with a total score ranging from 0 to 60. Higher scores indicate more severe symptoms. dizziness severity will be assessed using the Vertigo Symptom Scale-Short Form.
Baseline, immediately after the 4-week intervention, and 2 months after the end of treatment
Change in kinesiophobia assessed by Tampa Kinesiophobia Scale
大体时间:Baseline, immediately after the 4-week intervention, and 2 months after the end of treatment
Change in kinesiophobia will be assessed using the Tampa Scale for Kinesiophobia (TSK). The TSK consists of 17 items scored from 1 to 4, with total scores ranging from 17 to 68. Higher scores indicate greater fear of movement.
Baseline, immediately after the 4-week intervention, and 2 months after the end of treatment
Change in quality of life assessed by Short Form-36
大体时间:Baseline, immediately after the 4-week intervention, and 2 months after the end of treatment
Change in quality of life will be assessed using the Short Form-36 Health Survey (SF-36). The SF-36 consists of 8 subscales scored from 0 to 100, with higher scores indicating better health status.
Baseline, immediately after the 4-week intervention, and 2 months after the end of treatment
Change in balance confidence assessed by Activities-specific Balance Confidence Scale
大体时间:Baseline, immediately after the 4-week intervention, and 2 months after the end of treatment
Change in balance confidence will be assessed using the Activities-specific Balance Confidence Scale (ABC). The ABC includes 16 items scored from 0% to 100%, with higher scores indicating greater balance confidence.
Baseline, immediately after the 4-week intervention, and 2 months after the end of treatment
Change in functional mobility assessed by Timed Up and Go Test
大体时间:Baseline, immediately after the 4-week intervention, and 2 months after the end of treatment
Change in functional mobility will be assessed using the Timed Up and Go Test (TUG). The time required to stand up, walk 3 meters, turn, and sit down is recorded in seconds. Lower times indicate better performance.
Baseline, immediately after the 4-week intervention, and 2 months after the end of treatment
Change in tandem balance performance assessed by tandem stance/walking duration
大体时间:Baseline, immediately after the 4-week intervention, and 2 months after the end of treatment
Change in dynamic balance will be assessed using tandem walking performance. The duration or number of steps maintained in tandem stance is recorded. Higher performance indicates better balance.
Baseline, immediately after the 4-week intervention, and 2 months after the end of treatment
Change in perceived benefit assessed by Vestibular Rehabilitation Benefit Questionnaire
大体时间:Baseline, immediately after the 4-week intervention, and 2 months after the end of treatment
Change in perceived benefit will be assessed using the Vestibular Rehabilitation Benefit Questionnaire (VRBQ). The questionnaire evaluates symptom severity and quality of life related to vestibular dysfunction. Raw scores are converted to percentage values ranging from 0 to 100. Higher scores indicate greater symptom severity and poorer quality of life.
Baseline, immediately after the 4-week intervention, and 2 months after the end of treatment

合作者和调查者

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出版物和有用的链接

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研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始 (估计的)

2026年4月27日

初级完成 (估计的)

2026年5月27日

研究完成 (估计的)

2026年7月27日

研究注册日期

首次提交

2026年4月23日

首先提交符合 QC 标准的

2026年4月23日

首次发布 (实际的)

2026年4月30日

研究记录更新

最后更新发布 (实际的)

2026年5月7日

上次提交的符合 QC 标准的更新

2026年5月4日

最后验证

2026年4月1日

更多信息

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不

研究美国 FDA 监管的设备产品

不

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