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Improving Dysphagia in Stroke Patients With Chin Tuck Against Resistance Exercise

2026年6月1日 更新者:HUANG CHIAO LIN、Taichung Veterans General Hospital

According to a 2014 report from the Ministry of Health and Welfare, cerebrovascular disease is one of the leading causes of death, with a mortality rate of 51.6 per 100,000 population, ranking fourth among the top ten causes of death. Stroke is often associated with symptoms such as unilateral weakness, slurred speech, facial asymmetry, and swallowing or speech difficulties, with approximately 42-67% of patients experiencing dysphagia.

Dysphagia is primarily associated with dysfunction of the pharyngeal muscles and impaired coordination, often accompanied by central nervous system dysfunction. Common symptoms include choking, coughing after eating, drooling, difficulty eating, and swallowing problems, which may lead to complications such as pneumonia and malnutrition.

Chin tuck against resistance (CTAR), developed by Yoon et al. in 2014, is a simple and non-invasive exercise aimed at improving pharyngeal muscle contraction, chewing and bolus formation, and coordination between the pharynx and upper esophagus. Previous studies suggest that CTAR exercises can effectively improve swallowing-related muscle function.

However, there is a lack of research targeting acute stroke patients in hospital settings. Therefore, this study is designed as a randomized controlled trial (RCT) to evaluate the effectiveness of CTAR exercises in improving dysphagia.

Participants will be randomly assigned to an experimental group or a control group. The experimental group will perform CTAR exercises once daily, five days per week, for two weeks, in addition to routine rehabilitation exercises until discharge. The control group will receive routine rehabilitation exercises once daily, five days per week.

Effectiveness will be assessed using a 90 mL water swallowing test and the Eating Assessment Tool-10 (EAT-10). Baseline measurements will be conducted prior to the intervention, and subsequent assessments will be performed every two days during the study period. Additional outcomes include changes in EAT-10 scores and the removal rate of nasogastric tubes before discharge.

研究概览

详细说明

According to a 2014 report from the Ministry of Health and Welfare, cerebrovascular disease is one of the leading causes of death, with a mortality rate of 51.6 per 100,000 population, ranking fourth among the top ten causes of death. Stroke is commonly associated with neurological deficits such as hemiparesis, dysarthria, facial asymmetry, and dysphagia. Approximately 42-67% of stroke patients experience swallowing difficulties.

Dysphagia in stroke patients is primarily related to dysfunction of pharyngeal muscles and impaired coordination of the swallowing mechanism, often accompanied by central nervous system impairment. Common clinical manifestations include choking, coughing during or after meals, drooling, difficulty chewing and swallowing, which may lead to serious complications such as aspiration pneumonia and malnutrition.

Chin tuck against resistance (CTAR), first introduced by Yoon et al. in 2014, is a simple and non-invasive exercise designed to strengthen suprahyoid muscles, improve pharyngeal contraction, enhance bolus control, and facilitate coordination between the pharynx and upper esophageal sphincter. Previous studies have demonstrated that CTAR exercise can effectively improve swallowing-related muscle function.

However, there remains a lack of evidence focusing on acute stroke patients in hospital settings. Therefore, this study is designed as a randomized controlled trial (RCT) to evaluate the effectiveness of CTAR exercise in improving dysphagia among hospitalized stroke patients.

Participants will be randomly assigned to an experimental group or a control group. The experimental group will perform CTAR exercise once daily, five days per week, for two consecutive weeks, in addition to routine rehabilitation. The control group will receive routine rehabilitation alone at the same frequency.

Swallowing function will be evaluated using a 90 mL water swallowing test and the Eating Assessment Tool-10 (EAT-10). Baseline assessments will be conducted prior to intervention, followed by repeated measurements every two days during the study period. Additional outcomes include changes in EAT-10 scores and the rate of nasogastric tube removal before discharge.

This study aims to determine whether CTAR exercise provides additional benefits over conventional rehabilitation in improving swallowing function in stroke patients, and to provide evidence for clinical rehabilitation practice.

研究类型

介入性

注册 (实际的)

112

阶段

  • 不适用

联系人和位置

本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。

学习地点

      • Taichung、台湾、407
        • Taichung Veterans General Hospital

参与标准

研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

  • 成人
  • 年长者

接受健康志愿者

不

描述

Inclusion Criteria:

  • Patients aged ≥ 20 years diagnosed with ischemic stroke
  • NIH Stroke Scale (NIHSS) score between 6 and 20
  • Conscious and able to communicate in Mandarin or Taiwanese
  • Failed the 90 mL water swallow test

Exclusion Criteria:

  • Cognitive impairment
  • Brainstem stroke or intracerebral hemorrhage
  • Diagnosed psychiatric disorder or dementia
  • Unstable vital signs
  • Presence of endotracheal tube or tracheostomy
  • History of cervical spine injury
  • Head-of-bed elevation restricted to less than 30 degrees
  • Nil per os (NPO) status as ordered by a physician

学习计划

本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。

研究是如何设计的?

设计细节

  • 主要用途:治疗
  • 分配:随机化
  • 介入模型:并行分配
  • 屏蔽:无(打开标签)

武器和干预

参与者组/臂
干预/治疗
实验性的:Experimental Group
Participants receive routine rehabilitation plus chin tuck against resistance (CTAR) exercise.
Participants perform chin tuck against resistance (CTAR) exercise once daily, five days per week, for two consecutive weeks. The exercise is conducted in addition to routine rehabilitation therapy to improve swallowing function.
Participants receive routine rehabilitation therapy once daily, five days per week, for two consecutive weeks.
有源比较器:Control Group
Participants receive routine rehabilitation therapy only.
Participants receive routine rehabilitation therapy once daily, five days per week, for two consecutive weeks.

研究衡量的是什么?

主要结果指标

结果测量
措施说明
大体时间
Swallowing function assessed by 90 mL water swallowing test
大体时间:Baseline and every 2 days during the 2-week intervention period
Swallowing function is evaluated using a 90 mL water swallowing test. Participants are assessed at baseline and every 2 days during the intervention period. The outcome is recorded as pass or fail to determine improvement in swallowing ability.
Baseline and every 2 days during the 2-week intervention period

次要结果测量

结果测量
措施说明
大体时间
Swallowing-related quality of life assessed by EAT-10
大体时间:Baseline and once weekly during the 2-week intervention period
The total score ranges from 0 to 40, with higher scores indicating more severe dysphagia symptoms. A score of 3 or higher is considered indicative of a risk of dysphagia
Baseline and once weekly during the 2-week intervention period

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

调查人员

  • 首席研究员:Hsiao-Chi Nieh, Nursing Supervisor、Taichung Veterans General Hospital

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始 (实际的)

2024年10月26日

初级完成 (实际的)

2026年4月20日

研究完成 (实际的)

2026年4月23日

研究注册日期

首次提交

2026年6月1日

首先提交符合 QC 标准的

2026年6月1日

首次发布 (实际的)

2026年6月5日

研究记录更新

最后更新发布 (实际的)

2026年6月5日

上次提交的符合 QC 标准的更新

2026年6月1日

最后验证

2024年6月1日

更多信息

与本研究相关的术语

计划个人参与者数据 (IPD)

计划共享个人参与者数据 (IPD)?

不

IPD 计划说明

Individual participant data (IPD) will not be shared due to privacy and confidentiality concerns. The dataset contains sensitive clinical information, and sharing is restricted to protect participant identity in accordance with institutional policies and ethical regulations.

药物和器械信息、研究文件

研究美国 FDA 监管的药品

不

研究美国 FDA 监管的设备产品

不

此信息直接从 clinicaltrials.gov 网站检索,没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求,请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改,我们的网站上也会自动更新.

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