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Exercise Snacking and Cardiometabolic Health

2026年7月21日 更新者：Gregory Ruegsegger、University of Wisconsin, River Falls

Influence of Exercise Snacking on Cardiometabolic Health, Physical Activity, and Psychological Well-Being

Regular physical activity is associated with numerous health benefits, yet many young adults do not achieve recommended levels of physical activity. Exercise snacking, which involves performing brief bouts of physical activity throughout the day, may provide a practical alternative to traditional exercise programs by making physical activity easier to incorporate into daily routines.

This randomized controlled trial will evaluate whether a 12-week exercise snacking intervention improves physical activity levels, aerobic fitness, cardiometabolic health, and psychological well-being in insufficiently active young adults. Participants will be randomly assigned to either an exercise snacking intervention or a usual behavior control group. Assessments will be completed at baseline, after the 12-week intervention, and after an additional 12-week follow-up period to determine whether any changes are maintained after the intervention ends.

The study will measure physical activity using wearable activity monitors and assess aerobic fitness, body composition, blood pressure, blood lipids, glucose, exercise motivation, affective responses to exercise, and mental well-being. The findings will help determine whether exercise snacking is an effective and sustainable strategy for improving health in young adults and may inform future physical activity recommendations and interventions

研究概览

地位

招聘中

条件

干预/治疗

详细说明

Regular physical activity reduces the risk of cardiovascular disease, type 2 diabetes, obesity, and other chronic health conditions. Despite these well-established benefits, many young adults do not achieve recommended levels of physical activity. Commonly reported barriers include limited time, competing academic or work demands, and difficulty maintaining structured exercise programs.

Exercise snacking, defined as accumulating multiple brief bouts of moderate-to-vigorous physical activity throughout the day, has emerged as a potential strategy for increasing physical activity while minimizing many of the barriers associated with traditional exercise programs. Although short bouts of physical activity have demonstrated favorable acute physiological effects, relatively few randomized controlled trials have evaluated whether exercise snacking produces sustained improvements in objectively measured physical activity, physical fitness, cardiometabolic health, and psychological outcomes in free-living young adults.

The purpose of this study is to determine whether a 12-week exercise snacking intervention improves physical activity behavior, aerobic fitness, cardiometabolic health, exercise motivation, affective responses to physical activity, and psychological well-being compared with a usual behavior control group. Participants will be randomly assigned to either an exercise snacking intervention or a control condition. Following completion of the intervention, participants will be observed for an additional 12 weeks to evaluate the maintenance of behavioral and physiological changes after structured support is withdrawn.

The primary objectives are to determine whether exercise snacking increases objectively measured physical activity and improves aerobic fitness. Secondary objectives are to evaluate changes in body composition, blood pressure, fasting cardiometabolic biomarkers, exercise motivation, affective responses to exercise, and psychological well-being. Exploratory analyses will examine whether changes in motivation and affective responses are associated with long-term maintenance of physical activity during the follow-up period.

This study will contribute to the growing evidence regarding practical, scalable approaches for increasing physical activity among young adults and may help inform future lifestyle interventions and public health recommendations aimed at promoting long-term engagement in regular physical activity

研究类型

介入性

注册 (估计的)

60

阶段

  • 不适用

联系人和位置

本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。

学习联系方式

研究联系人备份

学习地点

  • 美国
    • Wisconsin
      • River Falls、Wisconsin、美国、54022
        • 招聘中
        • University of Wisconsin-River Falls
        • 接触：
        • 接触：
        • 首席研究员：
          • Gregory Ruegsegger, PhD

参与标准

研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

  • 成人

接受健康志愿者

是的

描述

Inclusion Criteria:

  • Age 18-60 years.
  • Body mass index (BMI) ≥18.5 kg/m².
  • Insufficiently physically active, defined as generally not meeting current physical activity guidelines for moderate-to-vigorous physical activity.
  • Able to safely participate in moderate-to-vigorous physical activity as determined by study screening procedures, including completion of the Physical - Activity Readiness Questionnaire (PAR-Q+) and health history review.
  • Willing and able to provide written informed consent.
  • Willing to complete all study visits, wear activity monitors, and comply with study procedures.

Exclusion Criteria:

  • Known cardiovascular, pulmonary, metabolic, neurological, orthopedic, or other medical conditions that would make participation in moderate-to-vigorous physical activity unsafe.
  • Resting heart rate >100 beats/minute at screening.
  • Resting blood pressure >160/100 mmHg at screening.
  • Clinically significant electrocardiogram (ECG) abnormalities identified during screening that require medical evaluation.
  • Current participation in regular structured physical activity that meets or exceeds recommended physical activity guidelines.
  • Physical limitations or injuries that preclude safe participation in the intervention or fitness testing.
  • Moderate-to-severe psychological distress or other mental health concerns identified during screening that require referral or would make study participation inappropriate.
  • Pregnancy or any other condition judged by the investigators to make participation unsafe or interfere with completion of study procedures.

学习计划

本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。

研究是如何设计的？

设计细节

  • 主要用途：基础科学
  • 分配：随机化
  • 介入模型：并行分配
  • 屏蔽：无（打开标签）

武器和干预

参与者组/臂
干预/治疗
实验性的：Exercise Snacking
Participants assigned to the exercise snacking group will complete a 12-week intervention consisting of multiple brief bouts (approximately 1-3 minutes each) of moderate-to-vigorous physical activity performed throughout the day. Participants will receive written instructions, examples of appropriate exercise snacks, and periodic check-ins to support adherence. The intervention is designed to increase daily physical activity by integrating short bouts of exercise into normal daily routines.
行为的：Exercise Snacking
Participants assigned to the intervention group will complete multiple brief bouts of moderate-to-vigorous physical activity throughout each day for 12 weeks. Each exercise snack will typically last approximately 1-3 minutes and may include activities such as stair climbing, brisk walking, repeated sit-to-stands, body-weight squats, or other moderate-to-vigorous activities that can be incorporated into daily routines. Participants will receive standardized written instructions, examples of exercise snacks, and periodic follow-up visits to monitor adherence and reinforce study procedures.
无干预：Usual Behavior Control
Participants assigned to the control group will continue their usual daily activities for 12 weeks and will not receive instruction regarding exercise snacking or any structured physical activity program during the intervention period. They will complete the same outcome assessments as participants in the intervention group.

研究衡量的是什么？

主要结果指标

结果测量
措施说明
大体时间
Moderate-to-Vigorous Physical Activity
大体时间：Baseline, Week 12, and Week 24
Average daily minutes of moderate-to-vigorous physical activity measured objectively using an accelerometer worn for seven consecutive days.
Baseline, Week 12, and Week 24

次要结果测量

结果测量
措施说明
大体时间
Body Fat Percentage
大体时间：Baseline, Week 12, Week 24
Body composition measured using air displacement plethysmography (BodPod).
Baseline, Week 12, Week 24
Aerobic Fitness
大体时间：Baseline, Week 12, and Week 24
Aerobic fitness assessed during a submaximal cycle ergometer exercise test with respiratory gas analysis using a metabolic measurement system.
Baseline, Week 12, and Week 24
Fasting Blood Glucose
大体时间：Baseline, Week 12, Week 24
Capillary fasting glucose measured using the Cholestech LDX analyzer.
Baseline, Week 12, Week 24
Blood Lipid Profile
大体时间：Baseline, Week 12, Week 24
Total cholesterol, HDL cholesterol, LDL cholesterol, and triglycerides measured from fasting capillary blood samples.
Baseline, Week 12, Week 24
Exercise Motivation
大体时间：Baseline, Week 12, Week 24
Exercise motivation will be assessed using the 24-item Behavioral Regulation in Exercise Questionnaire-3 (BREQ-3). The questionnaire produces six subscale scores: amotivation, external regulation, introjected regulation, identified regulation, integrated regulation, and intrinsic regulation. Each subscale is calculated as the mean of four items and ranges from 0 to 4. Higher scores indicate a greater degree of the corresponding type of exercise motivation; therefore, higher scores do not uniformly represent a better or worse outcome.
Baseline, Week 12, Week 24
Psychological Well-Being
大体时间：Baseline, Week 12, Week 24
Psychological well-being will be assessed using the World Health Organization-Five Well-Being Index (WHO-5). The five items are summed to produce a raw total score ranging from 0 to 25. Higher scores indicate better psychological well-being.
Baseline, Week 12, Week 24
Depressive Symptoms
大体时间：Baseline, Week 12, Week 24
Depressive symptoms will be assessed using the 9-item Patient Health Questionnaire (PHQ-9). Items are summed to produce a total score ranging from 0 to 27. Higher scores indicate more severe depressive symptoms and therefore a worse outcome.
Baseline, Week 12, Week 24
Anxiety Symptoms
大体时间：Baseline, Week 12, Week 24
Anxiety symptoms will be assessed using the 7-item Generalized Anxiety Disorder scale (GAD-7). Items are summed to produce a total score ranging from 0 to 21. Higher scores indicate more severe anxiety symptoms and therefore a worse outcome.
Baseline, Week 12, Week 24
Perceived Stress
大体时间：Baseline, Week 12, Week 24
Perceived stress will be assessed using the 10-item Perceived Stress Scale (PSS-10). Items are summed after reverse-scoring the positively stated items, producing a total score ranging from 0 to 40. Higher scores indicate greater perceived stress and therefore a worse outcome.
Baseline, Week 12, Week 24

其他结果措施

结果测量
措施说明
大体时间
Everyday Cognitive Failures
大体时间：Baseline, Week 12, Week 24
Everyday cognitive failures will be assessed using the 25-item Cognitive Failures Questionnaire (CFQ). Items are summed to produce a total score ranging from 0 to 100. Higher scores indicate a greater frequency of everyday cognitive failures and therefore a worse outcome.
Baseline, Week 12, Week 24
Exercise-Related Affective Valence
大体时间：Baseline, Week 12, Week 24
Exercise-related affective valence will be assessed using the single-item Feeling Scale. Responses range from -5 ("very bad") to +5 ("very good"), with 0 representing "neutral." Higher scores indicate more positive affective valence and therefore a better outcome.
Baseline, Week 12, Week 24
Academic engagement (UWES-S)
大体时间：Baseline, Week 12, Week 24
Academic engagement will be assessed using the 9-item Utrecht Work Engagement Scale for Students (UWES-S-9), which measures vigor, dedication, and absorption in academic activities. Each item is scored from 0 ("never") to 6 ("always/every day"). Higher scores indicate greater academic engagement and therefore a better outcome.
Baseline, Week 12, Week 24

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

赞助

University of Wisconsin, River Falls

调查人员

  • 首席研究员：Gregory Ruegsegger, PhD、University of Wisconsin, River Falls

出版物和有用的链接

负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。

一般刊物

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始 (估计的)

2026年8月1日

初级完成 (估计的)

2027年12月31日

研究完成 (估计的)

2027年12月31日

研究注册日期

首次提交

2026年7月16日

首先提交符合 QC 标准的

2026年7月16日

首次发布 (实际的)

2026年7月21日

研究记录更新

最后更新发布 (实际的)

2026年7月23日

上次提交的符合 QC 标准的更新

2026年7月21日

最后验证

2026年7月1日

更多信息

与本研究相关的术语

关键字

其他相关的 MeSH 术语

其他研究编号

  • 2026-33

计划个人参与者数据 (IPD)

计划共享个人参与者数据 (IPD)？

是的

IPD 计划说明

De-identified individual participant data underlying the results reported in publications arising from this study may be shared with qualified researchers upon reasonable request to the Principal Investigator. Data will become available beginning six months after publication of the primary study results and remain available for up to five years. Requests should include a brief research proposal and analysis plan and will be evaluated based on scientific merit and the proposed use of the data. When applicable, a data use agreement will be required before data are shared. The study protocol, statistical analysis plan, data dictionary, and analytic code (if applicable) may also be made available. All data sharing will comply with institutional policies and applicable regulations to protect participant confidentiality.

IPD 共享时间框架

De-identified individual participant data and supporting documentation will be available beginning six months after publication of the primary study results and will remain available for five years thereafter.

IPD 共享访问标准

De-identified individual participant data, the study protocol, statistical analysis plan, and analytic code may be made available to qualified researchers upon reasonable request to the Principal Investigator. Requests should include a brief research proposal and analysis plan and will be evaluated based on scientific merit, investigator qualifications, and the proposed use of the data. When applicable, a data use agreement will be required prior to data sharing. All shared data will be de-identified and released in accordance with institutional policies and applicable regulations to protect participant confidentiality.

IPD 共享支持信息类型

  • 研究方案
  • 树液
  • 分析代码

药物和器械信息、研究文件

研究美国 FDA 监管的药品

不

研究美国 FDA 监管的设备产品

不

此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.

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