Pragmatic Mobile Health Trial to Promote Cancer Screening and Healthy Behaviors (mHEALTH)
Pragmatic Randomized Trial Using Mobile Health (mHealth) Technology to Change Cancer Screening Behavior and Promote Healthier Lifestyle
Cancer is the leading cause of death in Singapore, but many people who are eligible for breast, cervical, and colorectal cancer screening do not get screened on time. Many adults also have chronic health conditions such as high blood pressure, diabetes, high cholesterol, and obesity, which can often be reduced through healthier lifestyle habits. Although reminders for screening are available, they may not be enough to encourage long-term healthy behaviours.
This study will evaluate whether regular health messages delivered through a mobile health (mHealth) platform can help improve cancer screening participation and promote healthier lifestyles among Singaporean women aged 50-69 years. Participants will be randomly assigned to one of two groups. The control group will receive standard cancer screening reminders every six months. The intervention group will receive monthly evidence-based health messages, including information on cancer screening, healthy eating, physical activity, and other healthy lifestyle behaviours, delivered through the NUHS App (or a similar mobile platform) or SMS.
The study will compare whether more frequent and engaging health messages lead to higher participation in recommended cancer screening, greater engagement with the digital platform, and healthier lifestyle behaviours compared with standard reminders. The findings may help identify an effective and scalable digital approach to support cancer prevention and healthy ageing across Singapore.
研究概览
地位
详细说明
Cancer remains the leading cause of death in Singapore despite the availability of national screening programmes for breast, cervical, and colorectal cancers. Participation in recommended cancer screening remains below desired levels, while chronic diseases associated with unhealthy lifestyle behaviours continue to increase. Existing approaches to promoting preventive health often rely on infrequent reminders and may be insufficient to support sustained behavioural change.
Singapore's widespread use of smartphones and digital health platforms provides an opportunity to deliver scalable mobile health (mHealth) interventions. This pragmatic randomized trial will evaluate whether regular delivery of evidence-based health messages through the NUHS App (or a similar mobile platform) or SMS can improve participation in recommended cancer screening and promote healthier lifestyle behaviours among Singaporean women aged 50-69 years.
Participants will receive either standard screening reminders or a more intensive programme of health messages covering cancer screening, healthy diet, physical activity, weight management, and other preventive health topics. The study will evaluate whether a sustained digital engagement strategy is more effective than standard reminders in encouraging long-term health behaviour change.
Because the intervention is delivered using existing healthcare digital infrastructure, the findings will inform whether this approach can be implemented at scale to improve cancer prevention and support healthy ageing in Singapore.
研究类型
注册 (估计的)
阶段
- 不适用
联系人和位置
学习地点
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Singapore、新加坡
- National University Hospital Singapore
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参与标准
资格标准
适合学习的年龄
- 成人
- 年长者
接受健康志愿者
描述
Inclusion Criteria:
- If using app for message delivery: Registered NUHS App users or HealthHub App users OR if using SMS for message delivery: Participants must have a mobile number recorded in electronic medical records (EPIC).
- Female
- Singapore citizen
- Aged 50-69 years
- With or without prior diagnosis of cancer
Exclusion Criteria:
- Participants unable to provide informed consent and take surveys, such as those with cognitive impairments or severe mental health conditions.
- Participants with terminal illness or serious comorbidities that preclude them from participating in preventive health programs.
- Pregnant women: Given the target age group (50-69 years), the prevalence of pregnancy is expected to be extremely low.
学习计划
研究是如何设计的？
设计细节
- 主要用途：放映
- 分配：随机化
- 介入模型：并行分配
- 屏蔽：无（打开标签）
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
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其他：Standard Messaging Arm (Arm 1)
Participants receive standard cancer screening reminders through the NUHS App or SMS according to usual practice.
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Participants receive two standard health messages through PN via the NUHS app or similar platforms OR via SMS - one at recruitment and a subsequent reminder message after 6 months.
The content will include general population cancer screening guidelines (breast, colorectal, and cervical cancers) and information pertaining to healthy lifestyle practices (including maintaining a healthy BMI, balanced diet, and sufficient exercise).
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实验性的：Intensive Engagement Arm (Arm 2)
Participants receive regular evidence-based health messages through the NUHS App or SMS to promote cancer screening and healthy lifestyle.
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Participants will receive the standard bi-annual health messages as in Arm 1, supplemented with additional monthly messages through PN via the app OR via SMS, that provide comprehensive information on general population cancer screening guidelines, healthy lifestyle practices, motivational health messages, video links, and details about relevant events over a period of 12 months.
In addition to the monthly messages, participants will be invited to attend up to 12 webinars (on women's health/screening/nutrition/lifestyle related topics) and 12 in-person or virtual group events (like simple low-intensity exercise/ walking/ basic yoga/ tai chi/nutritional cooking etc.) over 12 months.
Interested participants may also be asked to join a moderated chatgroup (using Telegram app).
The chatgroup is intended to promote peer support and healthy habit building.
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Comparison of Screen-Adherent Participants Between Arm 1 and Arm 2
大体时间：24 months post-intervention
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Proportion of screen-adherent participants (in %) in Arm-2 versus Arm-1 at 24 months. Non-adherence at baseline is defined as not being fully adherent to screening guidelines for all three cancers (with cervical cancer screening excluded for those not sexually active). Adherence following the intervention is defined as showing at least one improvement in adherence (e.g., previously adherent to only cervical cancer screening, with subsequent adherence to colorectal cancer screening). |
24 months post-intervention
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Proportion of participants with BMI in the healthy range
大体时间：24 months post-intervention
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Proportion of participants (in %) with BMI in the healthy range (18.5-22.9
kg/m2) in Arm 1 vs Arm 2
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24 months post-intervention
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Proportion of participants achieving a daily goal of 10,000 steps
大体时间：24 months post-intervention
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Proportion of participants (in %) achieving a daily goal of 10,000 steps in Arm 1 vs Arm 2
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24 months post-intervention
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Proportion of participants with recommended moderate-intensity aerobic activity
大体时间：24 months post-intervention
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Proportion of participants (in %) with 150-300 minutes of moderate-intensity aerobic activity in Arm 1 vs Arm 2
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24 months post-intervention
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Proportion of participants eating recommended servings of fruits/vegetables daily at 24 months
大体时间：24 months post-intervention
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Proportion of participants eating at least 5 servings of fruits/vegetables daily in Arm 1 vs Arm 2
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24 months post-intervention
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合作者和调查者
调查人员
- 首席研究员：Soo-Chin Lee, MBBS, MRCP、National University Hospital, Singapore
研究记录日期
研究主要日期
学习开始 (估计的)
初级完成 (估计的)
研究完成 (估计的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
关键字
其他研究编号
- 2024-4448
计划个人参与者数据 (IPD)
计划共享个人参与者数据 (IPD)？
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