Anorexia Nervosa, Evaluation and MOdification of Attention (ANEMA)

completion of ABMT sessions aiming to decrease attentional avoidance of food. In a modified dot-probe task with pairs of food and non-food stimuli, the probe appears at the location of the food stimulus in 90% of the trials, aiming to focus participants' attention on those stimuli.

One group, labelled as "experimental group (TR group)", receives an attentional bias modification training (ABMT) which aims to decrease avoidance of food by focusing attention on food stimuli, while the other group, labelled as "control group (CT group)" receives a sham ABMT, which acts as a control and does not aim to modify attentional orientation. Both groups complete eight at-home sessions consisting of dot-probe task trials. In the TR group, the probe appears at the location of the food stimulus in 90% of trials (in order to orient participants' attention towards those stimuli), while in the CT group, the probe appears randomly and with equal probability behind the food or non-food stimulus in all trials (classic dot-probe task).

completion of ABMT sessions not aiming to modify attentional orientation. In a classic dot-probe task with pairs of food and non-food stimuli, the probe appears at the location of the food stimulus or the non-food stimulus randomly and with equal probability across trials.

One group, labelled as "experimental group (TR group)", receives an attentional bias modification training (ABMT) which aims to decrease avoidance of food by focusing attention on food stimuli, while the other group, labelled as "control group (CT group)" receives a sham ABMT, which acts as a control and does not aim to modify attentional orientation. Both groups complete eight at-home sessions consisting of dot-probe task trials. In the TR group, the probe appears at the location of the food stimulus in 90% of trials (in order to orient participants' attention towards those stimuli), while in the CT group, the probe appears randomly and with equal probability behind the food or non-food stimulus in all trials (classic dot-probe task).

Attentional bias towards food, measured with reaction times (measured in milliseconds) and accuracy of responses, during a dot-probe and an ARDPEI tasks. The combination of the two for each type of stimuli allow for the calculation of a Speed-Accuracy Composite Score (SACS, no unit of measure) for both food and non-food stimuli. An attentional bias towards food score is then obtained by subtracting the SACS obtained when the probe appears at the location of the non-food picture to the SACS obtained when the probe appears at the location of the food picture.

Attentional bias towards food, measured with fixation time and saccade latency (measured in milliseconds), during a dot-probe and an ARDPEI tasks. An attentional bias towards food score is then calculated by subtracting fixation time and saccade latency when the probe appears at the location of the non-food picture to the fixation time and saccade latency when the probe appears at the location of the food picture.

Cardiac activity, measured via an electrocardiogram, with two electrodes placed on the wrists. It is measured through heart rate (in beats per minute).

Autonomic reactivity to food stimuli, measured via an EKG for cardiac reactivity, a respiratory belt for respiratory reactivity, and electrodes placed on participants' fingers for electrodermal reactivity. Measured before and after the ABMT interventions (visits 1 and 2).

Psychometric outcomes, measured through validated questionnaires administered before and after the ABMT interventions (visits 1 and 2).

• Eating disorders symptoms, EDE-Q (Eating Disorder Examination Questionnaire). EDE-Q score is calculated by adding the score of each of the items.
• Depression, Anxiety, and Stress levels, DASS-42 (Depression, Anxiety, Stress, Scale - 42 items). DASS-42 score is calculated by adding the score of each of the items.
• Body image and body shape concerns, BSQ (Body Shape Questionnaire). BSQ score is calculated by adding the score of each of the items.
• Emotional regulation difficulties, DERS-SF (Difficulties in Emotional Regulation - Short Form). DERS-SF score is calculated by adding the score of each of the items.

Electrodermal activity, measured via electrodes specifically designed to measure electrodermal activity, placed on the non-dominant hand's index and major. It is measured through amplitude of skin conductance response (μS).

3) Respiratory activity, measured via a respiratory belt placed on the sternum. It is measured through respiratory frequency (cycles per minute)

Cutaneous temperature, measured via an electrode specifically designed to measure cutaneous temperature places on the non-dominant hand's ring finger. It is measured through the finger's temperature (in Celsius degrees).

Eating disorders symptoms, measured via the Eating Disorder Examination - Questionnaire (EDE-Q), which gives a score between 0 and 132, with a higher score meaning more severe eating disorders symptoms (worse outcome). The score is calculated by summing the items' score together.

Depression, Anxiety, and Stress levels, measured via the Depression, Anxiety, Stress scale - 42 items (DASS-42), which gives a score between 0 and 126, with a higher score meaning higher levels of depression, anxiety, and stress (worse outcome). The score is calculated by summing the items' score together.

Body image and body shape concerns, measured via the Body Shape Questionnaire (BSQ), which gives a score between 34 and 204, with a higher score meaning more body image and body shape concerns (worse outcome). The score is calculated by summing the items' score together.

Emotional regulation difficulties, measured via the Difficulties with Emotional Regulation Scale - Short Form (DERS-SF) which gives a score between 18 and 90, with a higher score meaning greater emotional regulation difficulties (worse outcome). The score is calculated by summing the items' score together.

Interoceptive sensibility, measured via the Multidimensional Assessment of Interoceptive Awareness (MAIA), which gives a score between 0 and 160, with a higher score meaning greater interoceptive sensibility (better outcome). The score is calculated by summing the items' score together.