Clinical Trials on Heart Defects

Total 68581 results

Asklepion Pharmaceuticals, LLC

Completed

Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery : Revised Protocol

Atrial Septal Defect | Atrioventricular Septal Defect | Ventricular Septal Defect

United States
Nobles Medical Technologies II Inc

Enrolling by invitation

Stitch Closure of PFO and Septal Repair (STITCH)

Foramen Ovale, Patent | Septal Defect, Atrial | Septal Defect, Heart

United States, Italy
HeartStitch.Com

Unknown

Stitch Closure of PFO and Septal Repair (STITCH)

Foramen Ovale, Patent | Septal Defect, Atrial | Septal Defect, Heart

United States
Nationwide Children's Hospital

Completed

Measures to Lower the Stress Response in Pediatric Cardiac Surgery

Tetralogy of Fallot (TOF) | Ventricular Septal Defects (VSD) | Atrioventricular Septal Defects (AVSD)

United States
Asklepion Pharmaceuticals, LLC

Recruiting

A Study Evaluating the Efficacy and Safety of IV L-Citrulline for the Prevention of Clinical Sequelae of Acute Lung Injury Induced by Cardiopulmonary Bypass in Pediatric Patients Undergoing Surgery for Congenital Heart Defects

Atrioventricular Septal Defect | Ventricular Septal Defect | Primum Atrial Septal Defect

United States
Occlutech International AB

Completed

Occlutech Septal Occluder (Figulla Flex II) Study

Secundum Atrial Septal Defects
Ayman khairy Mohamed

Completed

Assessment of LV/RV S and SR Before and After Percutaneous Closure of ASDs

Atrial Septal Defect, Secundum Type

Egypt
Abbott Medical Devices

Terminated

ADVANCE ASO AMPLATZER™ Atrial Septal Occluder Post Market Surveillance Study (ASO 522)

Atrial Septal Defect Secundum

United States
Occlutech International AB

Recruiting

Follow-up Study to Monitor the Efficacy and Safety of the Occlutech® mVSD Cases (mVSD Registry)

Muscular Ventricular Septal Defect

Turkey
W.L.Gore & Associates

Completed

Long-term Safety Study of the GORE® HELEX® Septal Occluder

Septal Defect, Atrial

United States
Henry Ford Health System

Withdrawn

Iatrogenic Atrial Septal Defect Study (iASD) (iASD)

Septal Defect, Atrial

United States
University Hospital, Toulouse
Philips Healthcare

Completed

Percutaneous Closure of Atrial Septal Defects in Children: Integration of 3D Echocardiography and Fluoroscopy Imaging. (CIA3DNAVIGATOR)

Atrial Septal Defects

France
Ain Shams University

Completed

Transcatheter Versus Surgical Closure of Ventricular Septal Defect: A Comparative Study

Heart Defects, Congenital

Egypt
Xijing Hospital

Completed

Transcatheter Closure Versus Surgery of Perimembranous Ventricular Septal Defects

Ventricular Septal Defects
Chinese Academy of Medical Sciences, Fuwai Hospital

Unknown

Minimally Invasive Transthoracic Device Closure in Perimembranous Ventricular Septal Defect

Perimembranous Ventricular Septal Defect

China
Abbott Medical Devices

Active, not recruiting

Closure of Muscular Ventricular Septal Defects (VSDs) With the AMPLATZER Muscular VSD (MuVSD) Occluder - Post Approval Study (VPA)

Ventricular Septal Defects

United States, Canada
Occlutech International AB

Active, not recruiting

A Multicenter, International, Follow-up Study to Monitor the Efficacy and Safety of the Occlutech® PmVSD Occluder in Patients With Perimembranous Ventricular Septal Defects

Perimembranous Ventricular Septal Defect

Thailand, Germany, Ireland, Vietnam
Nanjing Medical University

Completed

Hybrid Closure of Congenital Heart Disease

Pediatric Ventricular Septal Defects
Shanghai Zhongshan Hospital

Recruiting

The Puncturable Atrial Septal Defect Occluder Trial (the PASSER Trial)

Atrial Septal Defect

China
University Health Network, Toronto
St. Paul's Hospital, Canada; Montreal Heart Institute; Centre de Recherche de...

Recruiting

Comparison of Devices for Atrial Septal Defects Closure: A Pilot Study (Trio-ASD)

Atrial Septal Defect

Canada
W.L.Gore & Associates

Completed

Safety and Efficacy of the GORE® Septal Occluder to Treat Ostium Secundum Atrial Septal Defects

Septal Defect, Atrial

United States
Assiut University

Withdrawn

Outcomes of Transcatheter ASD Closure Guided by 3D-TEE

ASD2(Secundum Atrial Septal Defect)
Abbott Medical Devices

Completed

Closure of Perimembranous Ventricular Septal Defects With The AMPLATZER® Membranous VSD OCCLUDER

Membranous Ventricular Septal Defects

United States
University of California, San Francisco

Withdrawn

Aberrations in Carnitine Homeostasis in Congenital Heart Disease With Increased Pulmonary Blood Flow (L-carn)

Heart Septal Defects, Ventricular | Atrioventricular Septal Defect

United States
Abbott Medical Devices

Recruiting

Trevisio Post-Approval Study (TrevisioPAS)

PFO - Patent Foramen Ovale | VSD - Muscular Ventricular Septal Defect | PIVSD - Post Infarct Muscular Ventricular Septal Defect | ASD - Atrial Septal Defect

Spain, Germany, Poland, France, Italy, Netherlands, Switzerland
Lifetech Scientific (Shenzhen) Co., Ltd.

Not yet recruiting

Lifetech CeraFlex™ ASD Closure System Post-Market Clinical Follow-Up

Atrial Septal Defect

Italy, Brazil, Greece
Lifetech Scientific (Shenzhen) Co., Ltd.

Recruiting

Safety and Efficacy Study of Absnow Absorbable ASD Closure System For Treating ASD Patients

Atrial Septal Defect | Heart Septal Defects, Atrial

China
Chinese Academy of Medical Sciences, Fuwai Hospital

Unknown

A Prospective Randomized Multicenter Trial of the Guidewire for Echo-guided Interventions

Atrial Septal Defect

China
Duke University

Completed

Magnetic Resonance Imaging of Atrial Septal Defects

Atrial Septal Defect

United States
Abbott Medical Devices

Completed

Closure of Atrial Septal Defects With the AMPLATZER Septal Occluder - Post Approval Study

Atrial Septal Defect

United States
RWTH Aachen University

Unknown

The Effect of the Hole in the Cardiac Septum Developed by the MitraClip Procedure on the Blood Flow Mechanics (MitraClipASD)

Atrial Septal Defect

Germany
Institute of Cardiology, Warsaw, Poland

Unknown

Occluder Size Determination in Transcatheter ASD II Closure Based on 3D TEE Assessment

Ostium Secundum Atrial Septal Defect

Poland
Duke University
The Society of Pediatric Anesthesia

Recruiting

Regional Anesthesia Following Pediatric Cardiac Surgery

Atrial Septal Defect | Pain, Procedural | Ventricular Septal Defect

United States
W.L.Gore & Associates

Completed

Safety and Efficacy Study of Transcatheter Closure of Ostium Secundum ASDs (ASSURED)

Atrial Septal Defect

United States
University Hospitals of North Midlands NHS Trust

Completed

The Effect on EPCs by Successful Cardiac Occlusion Device Implantation (EPIC)

Atrial Septal Defect | Heart Septal Defects, Atrial | Foramen Ovale, Patent

United Kingdom
Dr. Soetomo General Hospital

Completed

Improvement In Left Ventricular Diameter After Closure Of ASD With Fenestrated Patch: A Cross-sectional Study

Atrial Septal Defect

Indonesia
University of Aarhus

Completed

Cardiopulmonary Function in Adults Born With a Ventricular Septal Defect

Ventricular Septal Defect

Denmark
Abbott Medical Devices

Completed

Closure of Muscular Ventricular Septal Defects With The AMPLATZER™ Muscular VSD Occluder

Heart Septal Defects, Ventricular

United States
Chinese Academy of Medical Sciences, Fuwai Hospital
Shanghai Shape Memory Alloy Co., Ltd.

Unknown

A Trial to Evaluate the Safety and Efficacy of a Fully Degradable Ventricular Septal Defect (VSD) Closure

Ventricular Septal Defect

China
University of Aarhus

Completed

Longterm Outcome After Ventricular Septal Defect Closure

Ventricular Septal Defect

Denmark
Bark Technology LLP

Recruiting

Evaluation of the Effectiveness and Safety of Vibro-acoustic Pulmonary Therapy (VAPT) in Complex Therapy for Acute Respiratory Failure of Mixed Type I-II Stages in Comparison With Percussion Massage in Cardiac Surgical Patients in the Early Postoperative Period

Cardiac Surgical Patients (CABG,Mammary Coronary Bypass Surgery,Plastic and Replacement of Valves, Atrial Septal Defect,Ventricular Septal Defect)

Kazakhstan
Asan Medical Center

Recruiting

Efficacy of Three Dimensional Transesophageal Echocardiography for Percutaneous Device Closure in Atrial Septal Defect (ASD)

Atrial Septal Defect | Successful Device Closure

Korea, Republic of
Lund University Hospital
Göteborg University; Region Jönköping County

Active, not recruiting

Improving Care for Children With Congenital Heart Disease.

Cardiovascular Diseases | Atrial Septal Defect | Patent Ductus Arteriosus | Ventricular Septal Defect | Aortopulmonary Window | Heart Disease Congenital | Partial Anomalous Pulmonary Venous Connection

Sweden
French Cardiology Society

Active, not recruiting

French Observatory of Congenital Ventricular Septal Defect With Pulmonary Overload (FRANCISCO)

Congenital Heart Disease

France
Universitaire Ziekenhuizen KU Leuven

Completed

Evaluation of Latent Pulmonary Arterial Hypertension in Congenital Shunt Lesions

Ventricular Septal Defects | Atrial Septal Defects

Belgium
Ludwig-Maximilians - University of Munich

Unknown

International Registry for ASD Closure by Using the Occlutech®Flex II Device in More Than 2000 Patients (IRFACODE-II)

Atrial Septal Defect
Third Military Medical University
Chongqing Medical University

Unknown

Study of Blood Clotting After Transcatheter Atrial Septal Defect Closure

Thrombosis

China
Tanta University

Recruiting

General Anesthesia Versus Sedation By Dexmedetomidine and Ketamine With Local Infiltration for Percutaneous Transcatheter Closure of Atrial Septal Defect in Pediatric Patients

Atrial Septal Defect | Ketamine | General Anesthesia | Dexmedetomidine | Local Infiltration

Egypt
National Taiwan University Hospital
E-DA Hospital

Unknown

Cardiac Function After Transcatheter VSD Closure

Ventricular Septal Defect

Taiwan
Universitaire Ziekenhuizen KU Leuven

Completed

Evaluation of Dynamic Pulmonary Vascular Resistance in Patients With Closed Ventricular Septal Defect

Pulmonary Vascular Disease

Belgium

Clinical Trials on Heart Defects

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Serbia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations