Clinical Trials on High-Risk Localized Prostate Cancer

Total 7551 results

Memorial Sloan Kettering Cancer Center
Progenics Pharmaceuticals, Inc.

Active, not recruiting

Prostate-Specific Membrane Antigen (PSMA) PET Scans in People Prostate Cancer

Prostate Cancer | Metastatic Prostate Cancer | Prostate Adenocarcinoma | Prostate Cancer Metastatic | Prostate Neoplasm

United States
Cedars-Sinai Medical Center
National Cancer Institute (NCI)

Recruiting

RCT of NLP-Based Feedback for Improving SDM in Men With Localized Prostate Cancer (NLP RCT)

Prostate Cancer | Shared Decision Making | Risk Communication

United States
University College, London
Blue Earth Therapeutics Ltd

Recruiting

ACTinium in Castrate-RESistant Prostate Cancer After LUTEtium (ACT-RESoLUTE)

Prostate Cancer | Metastatic Prostate Cancer | Metastatic Castration-resistant Prostate Cancer

United Kingdom
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Stereotactic Body Radiation Therapy in Treating Patients With Prostate Cancer After Undergoing Surgery

Recurrent Prostate Cancer | Stage I Prostate Cancer | Stage III Prostate Cancer | Stage IIA Prostate Cancer | Stage IIB Prostate Cancer

United States
University of Zurich

Active, not recruiting

Early Magnetic Resonance Imaging Response of the Dominant Intraprostatic Lesion After Online Adaptive Stereotactic Body Radiotherapy for Localized Prostate Cancer and Correlation With Prostate Specific Antigen Response (PRODART)

Magnetic Resonance Imaging | Prostate Carcinoma | Stereotactic Body Radiotherapy | Multiparametric MRI | Stereotactic Radiotherapy | Localized Prostate Adenocarcinoma

Switzerland
National Cancer Institute (NCI)

Active, not recruiting

18F-DCFPyL PET/CT in High Risk and Recurrent Prostate Cancer

Prostate Cancer | Metastatic Prostate Cancer | Cancer Of Prostate | Prostate Neoplasms | Prostatic Cancer

United States
Weill Medical College of Cornell University
Millennium Pharmaceuticals, Inc.

Completed

A Phase II Trial of MLN8237 in Patients With Metastatic Castrate Resistant and Neuroendocrine Prostate Cancer

Neuroendocrine Prostate Cancer | Small Cell Prostate Cancer | Prostate Adenocarcinoma Plus > 50% Immunohistochemical Staining for Neuroendocrine Markers

United States
Mayo Clinic
National Cancer Institute (NCI)

Withdrawn

Daily, Long-Term Intermittent Fasting for the Prevention of PSA-Recurrence in Patients With Localized Prostate Cancer After Radical Prostatectomy

Stage I Prostate Cancer AJCC v8 | Stage II Prostate Cancer AJCC v8 | Stage IIIA Prostate Cancer AJCC v8 | Stage IIIB Prostate Cancer AJCC v8 | Stage IIC Prostate Cancer AJCC v8 | Stage III Prostate Cancer AJCC v8 | Stage IIIC Prostate Cancer AJCC v8 | Stage IIA Prostate Cancer AJCC v8 | Stage IIB Prostate...

United States
National Cancer Institute (NCI)

Terminated

Perifosine in Treating Patients With Recurrent Prostate Cancer

Recurrent Prostate Cancer | Stage III Prostate Cancer | Adenocarcinoma of the Prostate | Stage IV Prostate Cancer | Stage IIB Prostate Cancer

United States
Peking University First Hospital

Active, not recruiting

Clinically Actionable Tumor-Associated Antigens in Prostate Cancer

Prostate Cancer | Metastatic Prostate Cancer | Metastatic Prostate Cancer (mCRPC)

China
Stanford University
National Cancer Institute (NCI)

Active, not recruiting

High-Dose Brachytherapy in Treating Patients With Prostate Cancer

Prostate Adenocarcinoma | Stage I Prostate Cancer | Stage III Prostate Cancer | Stage IIA Prostate Cancer | Stage IIB Prostate Cancer

United States
National Cancer Institute (NCI)

Terminated

Photodynamic Therapy With Lutetium Texaphyrin in Treating Patients With Locally Recurrent Prostate Cancer

Recurrent Prostate Cancer | Stage I Prostate Cancer | Adenocarcinoma of the Prostate | Stage IIA Prostate Cancer | Stage IIB Prostate Cancer

United States
National Cancer Institute (NCI)

Completed

Highly Conformal, Hypofractionated, Focally Dose Escalated Post-Prostatectomy Radiotherapy

Prostate Cancer | Neoplasms of Prostate | Cancer Of Prostate | Prostate Neoplasms | Prostatic Cancer

United States
National Cancer Institute (NCI)

Completed

Zoledronate and BMS-275291 in Treating Patients With Prostate Cancer

Recurrent Prostate Cancer | Adenocarcinoma of the Prostate | Stage IV Prostate Cancer

United States
University of Southern California
National Cancer Institute (NCI)

Terminated

Cell-Free DNA and RNA in Blood fromMetastatic Prostate Cancer Patients

Metastatic Prostate Carcinoma | Prostate Adenocarcinoma | Hormone-Resistant Prostate Cancer

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
AstraZeneca

Recruiting

The Study of Olaparib in Newly Diagnosed mCRPC Patients With HRR Gene Mutation (PROspect)

Prostate Cancer | Prostate Carcinoma | Metastatic Castration-resistant Prostate Cancer

China
Ruijin Hospital

Not yet recruiting

The Efficacy and Safety of Sonrotoclax, Zanubrutinib Combined With Obinutuzumab in MCL

Intermediate-to-High-Risk Mantle Cell Lymphoma | the Efficacy and Safety

China
Astellas Pharma Global Development, Inc.

Recruiting

A Study to Evaluate the Safety and Drug Levels of ASP5541 in Chinese Participants With Prostate Cancer

Prostate Cancer | Metastatic Castration-Resistant Prostate Cancer | Metastatic Hormone Sensitive Prostate Cancer

China
Bin Xu
The First People's Hospital of Lianyungang

Not yet recruiting

Memantine Hydrochloride in Prostate Cancer Patients

Prostate Cancer | Metastatic Castration-resistant Prostate Cancer (mCRPC) | Neuroendocrine Prostate Cancer (NEPC)
Massachusetts General Hospital
Bayer

Completed

A Biomarker Study of Standard-of-care Radium-223 Chloride for Metastatic Castration-resistant Prostate Cancer

Prostate Cancer | Castration-resistant Prostate Cancer | Castration-resistant Prostate Cancer Metastatic to Bone

United States
National Cancer Institute (NCI)

Completed

AZD0530 in Treating Patients With Prostate Cancer That Did Not Respond to Hormone Therapy

Recurrent Prostate Cancer | Hormone-resistant Prostate Cancer

United States
Ipsen

Completed

Effects of Triptorelin Pamoate 6-month When Given to Adult Chinese Participants With Advanced Cancer in the Prostate

Metastatic Prostate Cancer | Advanced Prostate Cancer | Locally Advanced Prostate Cancer

China
University of Wisconsin, Madison
United States Department of Defense

Recruiting

Trial of pTVG-HP+Nivo+Targeted Ablation of Resistant Lesions in Non-Castrate RecurrentOMPC

Recurrent Prostate Cancer | Prostate Cancer Patients | Oligometastatic Prostate Cancer (OMPC) | Non-castrate Prostate Cancer

United States
Community Cancer Center, Normal, Illinois

Unknown

A Phase II Trial of CyberKnife Stereotactic Radiosurgery to Prostate Tumors

Prostate Cancer | Prostate Neoplasm | Cancer of the Prostate

United States
University Hospital Tuebingen
Ludwig-Maximilians - University of Munich; University Hospital Freiburg; University... and other collaborators

Not yet recruiting

Patients With Metastasized Prostate Cancer Whose Prostate-specific Antigen-level (PSA) Remains >0,2 ng/ml After Six Months of Dual Antihormonal Therapy Will Receive Radiotherapy to the Prostate and Radiotherapy to Refractory Metastases (RIALTO)

Prostate Cancer | Prostate Cancer Metastatic Disease | Prostate Cancer Metastatic to Bone
Janux Therapeutics

Recruiting

Study of JANX014 in Subjects With Metastatic Castration-Resistant Prostate Cancer

Prostate Cancer | Castration-resistant Prostate Cancer | Metastatic Castration-resistant Prostate Cancer

United States
Fundacao Champalimaud

Unknown

Single Dose Radiotherapy (SDRT) With or Without Adjuvant Systemic Therapy for Oligometastatic Prostate Cancer

Metastatic Prostate Cancer | Prostate Adenocarcinoma

Portugal
Sidney Kimmel Cancer Center at Thomas Jefferson...
National Institutes of Health (NIH)

Completed

Copper Cu 64 TP3805 PET in Detecting Cancer in Patients With Prostate Cancer Undergoing Surgery

Prostate Adenocarcinoma | Stage III Prostate Cancer | Stage IV Prostate Cancer | Stage IIB Prostate Cancer

United States
Dana-Farber Cancer Institute
Eli Lilly and Company

Active, not recruiting

TRADE: Dose Escalation Tolerability of Abemaciclib in HR+ HER2- Early Stage Breast Cancer

Breast Cancer | Early-stage Breast Cancer | High Risk Breast Carcinoma

United States
Alliance Foundation Trials, LLC.
Bayer

Completed

Androgen Receptor Directed Therapy on Cognitive Function in Patients Treated With Darolutamide or Enzalutamide (ARACOG)

Prostate Cancer | Metastatic Prostate Cancer | Prostate Cancer Metastatic | Castrate Resistant Prostate Cancer | Non-metastatic Prostate Cancer | Hormone Sensitive Prostate Cancer

United States
University of Southern California
National Cancer Institute (NCI)

Completed

Diffusion-Weighted MRI in Staging Patients With Localized Prostate Cancer

Adenocarcinoma of the Prostate | Stage IIA Prostate Cancer | Stage IIB Prostate Cancer

United States
Hospital Clinic of Barcelona

Completed

Effectiveness of Prehabilitation Program for High-risk Patients Underwent Abdominal Surgery

High-risk Patient | Abdominal Surgical Patient

Spain
Cairo University

Unknown

Antibacterial Effect of Guava Leaves Extract Mouthwash Compared to Chlorhexidine Mouthwash in High Caries Risk Patients

High Caries Risk Patients | Antimicrobial Effect | Salivary pH | Patient Satisfaction to Taste
Exact Imaging

Completed

Urology of Virginia Case Series

Prostate Cancer | Prostatic Neoplasm | Cancer of the PROSTATE

United States
National Cancer Institute (NCI)

Completed

A Phase II Study of PROSTVAC-V (Vaccinia)/TRICOM and PROSTVAC-F (Fowlpox)/TRICOM With GM-CSF in Patients With PSA Progression After Local Therapy for Prostate Cancer

Recurrent Prostate Carcinoma | Stage I Prostate Cancer | Stage III Prostate Cancer | Stage IIA Prostate Cancer | Stage IIB Prostate Cancer

United States
Amasya University

Recruiting

Effect of Hypnobreastfeeding Education in High-Risk Pregnant Women

Breast Feeding | High-risk Pregnancy

Turkey (Türkiye)
QH Medical Technology Ltd.

Not yet recruiting

Verify the Safety and Effectiveness of the Cerclage Pessary in Prevention and Treatment of High-risk Preterm Pregnancy

High Risk Pregnancy
KDH Research & Communication
National Institute on Minority Health and Health Disparities (NIMHD)

Completed

Monitoring and Outreach for Maternal Safety Postpartum (MOMSPostpartum)

Self Efficacy | Attitude | Postpartum | Intention | Knowledge | Community Health Workers | Women | High-risk

United States
Adam S. Kibel, MD
National Cancer Institute (NCI)

Recruiting

Polygenic Risk Stratification Combined With mpMRI to Identify Clinically Relevant Prostate Cancer (PRS)

Prostate Cancer | Polygenic Risk Score

United States
University of Chicago
National Cancer Institute (NCI)

Completed

MR-Guided Laser Interstitial Thermal Therapy in Treating Patients With Prostate Cancer

Stage II Prostate Carcinoma | Stage I Prostate Cancer

United States
Beijing Biotech

Recruiting

Dual-target PSMA/PSCA CAR-NK Cells in Advanced Prostate Cancer (DUAL-NK-PC)

Metastatic Castration-resistant Prostate Cancer | Advanced Prostate Adenocarcinoma | PSMA-Positive Progressive Metastatic Castration-Resistant Prostate Cancer | PSCA-positive Prostate Cancer

China
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Completed

LHRH Analogue Therapy With Enzalutamide or Bicalutamide in Treating Patients With Hormone Sensitive Prostate Cancer

Recurrent Prostate Cancer | Adenocarcinoma of the Prostate | Stage IV Prostate Cancer

United States
National Cancer Institute (NCI)

Completed

Treating Patients With Metastatic Prostate Cancer Not Responding to Hormone and Chemotherapy

Recurrent Prostate Cancer | Adenocarcinoma of the Prostate | Stage IV Prostate Cancer

United States
National Cancer Institute (NCI)

Completed

SB-715992 in Treating Patients With Metastatic Prostate Cancer That Did Not Respond to Docetaxel or Paclitaxel

Recurrent Prostate Cancer | Adenocarcinoma of the Prostate | Stage IV Prostate Cancer

United States
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Safety and Efficacy Study of SHR3680 in Metastatic Castration-Resistant Prostate Cancer Patients

Hormone Refractory Prostate Cancer | Metastatic Prostate Carcinoma

China
University of Southern California
National Cancer Institute (NCI)

Terminated

Molecular Characterization of CTCs and ctDNA in Blood and Plasma Samples From Patients With Metastatic and/or Hormone-Resistant Prostate Cancer

Metastatic Prostate Carcinoma | Hormone-Resistant Prostate Cancer

United States
University of Southern California
National Cancer Institute (NCI)

Completed

Oxaliplatin and Pemetrexed Disodium in Treating Patients With Refractory Hormone-Resistant Prostate Cancer

Recurrent Prostate Cancer | Hormone-resistant Prostate Cancer

United States
Ohio State University Comprehensive Cancer Center

Completed

Aborption and Metabolism of Lyophilized Black Raspberry Food Products in Men With Prostate Cancer Undergoing Surgery

Stage I Prostate Cancer | Stage III Prostate Cancer | Stage IIA Prostate Cancer | Stage IIB Prostate Cancer

United States
AstraZeneca

Completed

Retrospective Study to Describe the Real-world Treatment Patterns and Associated Clinical Outcomes in Patients With Metastatic Castration-resistant Prostates Cancer (REMPRO)

Metastatic Castration-resistant Prostates Cancer

India, Peru, Saudi Arabia, Egypt, Colombia, Korea, Republic of, Turkey, United Arab Emirates
University of Illinois at Chicago

Recruiting

BRE-04: Window of Opportunity Trial of Preoperative Low Dose Azacitidine in High-Risk Early Stage Breast Cancer (BRE-04)

Early-stage Breast Cancer | Breast Cancer Invasive | High Risk Breast Carcinoma

United States

Clinical Trials on High-Risk Localized Prostate Cancer

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