Clinical Trials on High-Risk Non-Muscle-Invasive Bladder Cancer

Total 838 results

Sun Yat-sen University
Novartis

Completed

Efficacy and Safety Study of ZOMETA® in Treatment of High-level NTX Non Small Cell Lung Cancer With Bone Metastasis

Non Small Cell Lung Cancer | Bone Metastases | High NTX Level

China
Fudan University

Completed

Transcutaneous Electrical Nerve Stimulation in Nerve-Sparing Radical Hysterectomy: Effects on Bladder Management and Quality of Life in Cervical Cancer

Lower Urinary Tract Symptoms | Cervical Cancer | Urinary Retention | Pelvic Floor Muscle Weakness | Postoperative Bladder Dysfunction | Recovery of Bladder Function | Improvement in Pelvic Floor Muscle Strength | Enhancement of Quality of Life

China
Bayer

Completed

A Study to Test Asundexian for Preventing a Stroke Caused by a Clot in Participants After an Acute Ischemic Stroke or After a High-risk Transient Ischemic Attack, a So-called Mini Stroke (OCEANIC-STROKE)

Acute Non-cardioembolic Ischemic Stroke | Prevention of Ischemic Stroke | High-risk Transient Ischemic Attack

Canada, United States, Taiwan, Australia, Sweden, United Kingdom, China, Malaysia, Latvia, Japan, Spain, Brazil, Lithuania, Belgium, Switzerland, Israel, Poland, France, Slovakia, Bulgaria, Netherlands, Finland, Austria, Hungary, India, C... and more
Amgen

Terminated

Effect of Blinatumomab on Minimal Residual Disease (MRD) in Diffuse Large B-Cell Lymphoma (DLBCL) Subjects Post Autologous Hematopoietic Stem Cell Transplantation (aHSCT)

High-risk Diffuse Large B-cell Lymphoma

United States, Italy, Belgium, Switzerland, Australia, France, Greece
Lei Li

Unknown

Immunohistochemical Staining of p16 for the Screening of Cervical Cancer

Cervical Intraepithelial Neoplasia | Cervical Cancer Screening | Histology | p16 Protein | Cytology | High-risk Human Papillomavirus | Diagnostic Accuracy

China
Centre Leon Berard

Completed

Efficiency of Imatinib Treatment Maintenance or Interruption After 3 Years of Adjuvant Treatment in Patients With Gastrointestinal Stromal Tumours (GIST) (ImadGist)

Gastrointestinal Stromal Tumors | Resected Gastrointestinal Stromal Tumors | Non-metastatic | High Risk of Recurrence | KIT Gene Mutation

France
National Cancer Institute (NCI)

Recruiting

Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma

Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Recurrent Diffuse Large B-Cell Lymphoma, Not... and other conditions

United States
Karolinska Institutet
Region Stockholm

Active, not recruiting

Randomized Implementation of Primary HPV Testing in the Organized Screening for Cervical Cancer in Stockholm

High-grade Cervical Intraepithelial Neoplasia | Invasive Cervical Cancer

Sweden
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Melanoma | Sarcoma | Acute Myeloid Leukemia | Stage I Uterine Corpus Cancer AJCC v7 | Stage II Uterine Corpus Cancer AJCC v7 | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Chronic Myeloid Leukemia | Stage III Pancreatic... and other conditions

United States
Palleon Pharmaceuticals, Inc.

Completed

Glycan Mediated Immune Regulation With a Bi-Sialidase Fusion Protein (GLIMMER-01) (GLIMMER-01)

Melanoma | Cancer | Breast Cancer | Head and Neck Cancer | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | NSCLC | Non Small Cell Lung Cancer | Bladder Cancer | Colon Cancer | Urothelial Cancer | Oncology | CRC | Esophagogastric Junction Cancer | EGJ

United States
Emory University
National Cancer Institute (NCI); Pfizer; National Institutes of Health (NIH)

Completed

Palbociclib With Cisplatin or Carboplatin in Advanced Solid Tumors

Sarcoma | Head and Neck Cancer | Stage IIIA Non-Small Cell Lung Cancer | Stage IIIB Non-Small Cell Lung Cancer | Colorectal Cancer | Ovarian Cancer | Bladder Cancer | Stage IV Non-Small Cell Lung Cancer | Stage III Pancreatic Cancer | Stage IV Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IIIC Breast Cancer and other conditions

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Chemotherapy Combined With Adebrelimab and Apatinib as the Perioperative Treatment in Patients With Biliary Tract Cancer

Resectable Intrahepatic Cholangiocarcinoma With High Risk of Recurrence

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Busulfan, Fludarabine Phosphate, and Post-Transplant Cyclophosphamide in Treating Patients With Blood Cancer Undergoing Donor Stem Cell Transplant

Hematopoietic and Lymphoid Cell Neoplasm | Recurrent Hodgkin Lymphoma | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | High Risk Myelodysplastic Syndrome | Recurrent Non-Hodgkin Lymphoma | Recurrent Acute Lymphoblastic Leukemia | Recurrent Chronic... and other conditions

United States
National Cancer Institute (NCI)

Active, not recruiting

Veliparib With or Without Radiation Therapy, Carboplatin, and Paclitaxel in Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery

Lung Adenocarcinoma | Lung Large Cell Carcinoma | Stage IIIA Lung Non-Small Cell Cancer AJCC v7 | Minimally Invasive Lung Adenocarcinoma | Stage IIIB Lung Non-Small Cell Cancer AJCC v7 | Stage III Lung Non-Small Cell Cancer AJCC v7 | Lung Squamous Cell Carcinoma | Lung Adenocarcinoma, Mixed Subtype

United States
McMaster University
Canadian Breast Cancer Foundation

Completed

Trial Comparing Radioactive Seed Localization to Standard Procedure for Non-palpable Breast Cancers

Breast Cancer Invasive Nos | Stage 0 Breast Carcinoma

Canada
Genentech, Inc.
BioNTech SE

Completed

A Study of Autogene Cevumeran (RO7198457) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors

Melanoma | Head and Neck Cancer | Colorectal Cancer | Non-Small Cell Lung Cancer | Bladder Cancer | Triple Negative Breast Cancer | Renal Cancer | Other Solid Cancers

United States, United Kingdom, Germany, Canada, Netherlands, Sweden, Belgium, Spain
BicycleTx Limited

Active, not recruiting

Study BT5528-100 in Patients With Advanced Solid Tumors Associated With EphA2 Expression

Head and Neck Cancer | Ovarian Cancer | Triple Negative Breast Cancer | Non-small Cell Lung Cancer | Advanced Solid Tumor Historically Known for High EphA2 Expression | Urothelial Cancer | Gastric/Upper Gastrointestinal Cancer

United States, Spain, United Kingdom, Belgium, South Korea
European Institute of Oncology

Recruiting

Anal Cancer and/or Precancer Screening: Performance Analysis of the BD Onclarity™ HPV Assay on Anal Specimens

Anal Cancer | High-Risk Cancer | Anal Intraepithelial Neoplasia 2 | Anal Intraepithelial Neoplasia 1

Italy
Elephas

Recruiting

Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies (ELEPHAS-05)

Kidney Cancer | Cancer | Head and Neck Cancer | Colorectal Cancer | Bladder Cancer | Skin Cancer | Endometrial Cancer | Liver Cancer | TNBC, Triple Negative Breast Cancer | Advanced Solid Tumors Cancer | Immunotherapy | Melanoma (Skin Cancer) | DMMR Colorectal Cancer | MSI-H Colorectal Cancer | NSCLC (Non-small-cell...

United States
Stephan Grupp MD PhD
University of Pennsylvania

Recruiting

Orphan Indications for CD19 Redirected Autologous T Cells

Pediatric and Young Adult Patientswith Hypodiploid or t(17;19) B-ALL | Infants With Very High Risk KMT2A B-ALL | Patients With Central Nervous System Relapse Who Did Not Receive Cranial Radiation or Bone Marrow Transplantation

United States
University of the West of Scotland
Swansea University

Completed

The Influence of a High Intensity Physical Activity Intervention on a Selection of Health Related Outcomes: An Ecological Approach

To Assess the Impact of the HIT Intervention on Physiological Responses | To Assess the Role of a Secondary High School as a Setting for Promoting Healthy Eating and PA Behaviours | To Determine the Associations Between CVD Risk Factors at Baseline in 15 - 18 Year Old Youth

United Kingdom
Beth Israel Deaconess Medical Center
Johns Hopkins University; Dana-Farber Cancer Institute; AstraZeneca

Active, not recruiting

Olaparib In Metastatic Breast Cancer

Metastatic Breast Cancer | Invasive Breast Cancer | BRIP1 Gene Mutation | PALB2 Gene Mutation | ATM Gene Mutation | CHEK2 Gene Mutation | NBN Gene Mutation | RAD51 Gene Mutation | Somatic Mutation Breast Cancer (BRCA1) | Somatic Mutation Breast Cancer (BRCA2)

United States
Sociedad de Lucha Contra el Cáncer del Ecuador

Not yet recruiting

Omic Technologies Applied to the Study of B-cell Lymphoma for the Discovery of Diagnostic and Prognosis Biomarkers

Neoplasms | Lymphoma, B-Cell | Cancer | Non Hodgkin Lymphoma | Diffuse Large B Cell Lymphoma | High-grade B-cell Lymphoma | Metabolomics

Ecuador
European Institute of Oncology

Not yet recruiting

Minimal Residual Disease in Solid Malignancies (IMRD)

Breast Cancer | Gastric Cancer | Prostate Cancer | Non Small Cell Lung Cancer | High Grade Serous Ovarian Cancer
Children's Hospital of Philadelphia

Recruiting

Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT

Leukemia | Hemoglobinopathies | Immunodeficiency | MDS (Myelodysplastic Syndrome) | Inborn Errors of Metabolism | Bone Marrow Failure | Acquired Aplastic Anemia | High Risk Acute Myeloid Leukemia | Relapsed Non-Hodgkin Lymphoma | Relapse Leukemia | HLH | Inherited BMF Syndrome | High Risk Acute Lymphoblastic Leukemia and other conditions

United States
Merck Sharp & Dohme LLC

Completed

A Study of V934/V935 Vaccine in Cancer Participants With Selected Solid Tumors (V934-002)

Melanoma | Renal Cell Carcinoma | Breast Cancer | Prostate Cancer | Bladder Carcinoma | Colon Carcinoma | Non-Small Cell Lung Carcinoma | Upper GI Tract Carcinoma
Replimune Inc.
Bristol-Myers Squibb

Active, not recruiting

Study of RP1 Monotherapy and RP1 in Combination With Nivolumab (IGNYTE) (IGNYTE)

Cutaneous Melanoma | Non-Small Cell Lung Cancer (NSCLC) | Non-melanoma Skin Cancer (NMSC) | Microsatellite Instability-High (MSI-H)

United States, France, United Kingdom, Spain, Germany
NKGen Biotech, Inc.

Withdrawn

Safety and Preliminary Efficacy of SNK01 in Combination With Trastuzumab or Cetuximab in Subjects With Advanced HER2 or EGFR Cancers

Sarcoma | Cervical Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Metastatic Cancer | Bladder Cancer | Triple Negative Breast Cancer | Advanced Solid Tumor | HER2-positive Breast Cancer | Head and Neck Squamous Cell Carcinoma | EGF-R Positive Non-Small... and other conditions
Angle plc
MidLantic Urology, LLC

Terminated

Characterization of Circulating Tumor Cells (CTCs) in High Risk and Early Metastatic Prostate Cancer Patients Using Parsortix® System (CHARTER)

Prostate Cancer | Castration-resistant Prostate Cancer | Biochemically Recurrent Prostate Carcinoma | High Risk Prostate Carcinoma

United States
Rondo Therapeutics

Enrolling by invitation

A Phase 1/1b of RNDO-564 Single Agent or in Combination With Pembrolizumab in Bladder Cancer and Other Solid Tumors Associated With Nectin-4

Cervical Cancer | Cancer | Gastric Cancer | Non Small Cell Lung Cancer | Urothelial Carcinoma Bladder | Head and Neck Squamous Cell Cancer | Esophageal Squamous Cell Cancer | Triple Negative Breast Cancer (TNBC) | Gastroesophageal Junction (GEJ) Adenocarcinoma | Solid Tumors (Phase 1)

United States
Natera, Inc.

Recruiting

Sample Collection for Ongoing Research and Product Evaluation Study (SCORE)

Melanoma | Breast Cancer | Head and Neck Cancer | Pancreatic Cancer | Ovarian Cancer | Lung Cancer | Rectal Cancer | Prostate Cancer | Liver Cancer | Uterine Cancer | Gastroesophageal Cancer | Muscle Invasive Bladder Cancer

United States
Tianjin Medical University Second Hospital

Active, not recruiting

A Study of Toripalimab in Adjuvant Therapy After Resection of High-risk Renal Cancer (TUORA)

High-risk Renal Cell Carcinoma

China
Hacettepe University

Recruiting

Acute Effects of Visual Feedback-Assisted Inspiratory Muscle Training After Lobectomy

Exercise Training | Lobectomy | VATS | Respiratory Muscles | Lung Cancer (NSCLC)

Turkey (Türkiye)
Elephas
Hoosier Cancer Research Network

Active, not recruiting

Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform (ELEPHAS-02)

Kidney Cancer | Cancer | Colorectal Cancer | Hepatocellular Carcinoma (HCC) | Bladder Cancer | Skin Cancer | Endometrial Cancer | Urothelial Carcinoma Bladder | Solid Tumor Cancer | Liver Cancer | Cutaneous Melanoma | Immunotherapy | Squamous Cell Carcinoma Head and Neck Cancer (HNSCC) | DMMR Colorectal Cancer | MSI-H... and other conditions

United States
Peking Union Medical College Hospital

Not yet recruiting

Adjuvant Therapy for High-risk Hepatocellular Carcinoma Post Liver Transplantation

Liver Transplant; Complications | Recurrent Osteosarcoma | Hepatocarcinoma | High-Risk Cancer

China
GTx

Completed

Phase III Study of the Effect of GTx-024 on Muscle Wasting in Patients With Non-Small Cell Lung Cancer (NSCLC)

Non Small Cell Lung Cancer | Muscle Wasting

United States
Netherlands Open University
Maastricht University Medical Center; Dutch Cancer Society; Maastro Clinic, The... and other collaborators

Completed

The Effectiveness of the Screening Inventory of Psychosocial Problems (SIPP) in Cancer Patients

Breast Cancer | Colorectal Cancer | Lung Cancer | Prostate Cancer | Non-Hodgkin Lymphoma | Bladder Cancer | Cervix Cancer | Cancer of Skin | Cancer of Endometrium

Netherlands
Istituto Scientifico Romagnolo per lo Studio e...
Pierre Fabre Laboratories

Terminated

Open-label, Multicenter, Randomized Phase II Trial of Treatment With Cisplatin and Pemetrexed or Cisplatin and Oral Vinorelbine in Chemotherapy Naïve Patients Affected by Stage IIIB-IV Non-Squamous Non-Small Cell Lung Cancer With High Thymidylate Synthase Expression (HighTySy)

Carcinoma, Non-Small-Cell Lung | Secondary | Advanced Stage IIIB | High Thymidylate Synthase Expression

Italy
Northwestern University
National Cancer Institute (NCI)

Completed

Combination Chemotherapy and TAK-659 as Front-Line Treatment in Treating Patients With High-Risk Diffuse Large B Cell Lymphoma

Diffuse Large B-Cell Lymphoma | Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | High Grade B-Cell Lymphoma, Not Otherwise Specified | T-Cell/Histiocyte-Rich Large B-Cell Lymphoma | High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements | Diffuse Large B-Cell Lymphoma... and other conditions

United States
Genmab

Recruiting

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001) (RAINFOL-01)

Fallopian Tube Cancer | Mesothelioma | Triple Negative Breast Cancer | Endometrial Cancer | Non-small Cell Lung Cancer | Primary Peritoneal Carcinoma | Uterine Cancer | Breast Adenocarcinoma | High Grade Serous Ovarian Cancer | Platinum-resistant Ovarian Cancer (PROC) | High Grade Epithelial Ovarian Cancer | Hormone Receptor-positive/Her2 Negative Breast Cancer and other conditions

United States, China, Japan
HiberCell, Inc.
Covance

Terminated

A Study of HC-7366 to Establish the Maximum Tolerated Dose (MTD) and Recommended Phase 2 Dose (RP2D)

Clear Cell Renal Cell Carcinoma | Non Small Cell Lung Cancer | Squamous Cell Carcinoma of Head and Neck | Colo-rectal Cancer | Transitional Cell Carcinoma of the Bladder | Other Solid Tumors

United States
Mayo Clinic

Recruiting

Golcadomide and Rituximab as Bridging Therapy for Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma Before CAR T-cell Therapy

Recurrent Transformed Non-Hodgkin Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | Recurrent Aggressive B-Cell Non-Hodgkin Lymphoma | Refractory Aggressive B-Cell Non-Hodgkin Lymphoma | Recurrent... and other conditions

United States
National Cancer Institute (NCI)

Active, not recruiting

Combination Chemotherapy, Radiation Therapy, and Bevacizumab in Treating Patients With Newly Diagnosed Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery

Lung Adenocarcinoma | Lung Large Cell Carcinoma | Stage IIIA Lung Non-Small Cell Cancer AJCC v7 | Minimally Invasive Lung Adenocarcinoma | Stage IIIB Lung Non-Small Cell Cancer AJCC v7 | Lung Squamous Cell Carcinoma | Lung Adenosquamous Carcinoma

United States
Pfizer

Recruiting

A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors

Head and Neck Cancer | Pancreatic Cancer | Esophageal Cancer | Pancreatic Adenocarcinoma | Bladder Cancer | Esophageal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Urothelial Carcinoma | Advanced Non-Small Cell Lung Cancer | Gastroesophageal Junction Adenocarcinoma | Carcinoma, Squamous Cell of Head... and other conditions

United States, Canada, Spain, United Kingdom, Puerto Rico
Maastricht University Medical Center

Active, not recruiting

Needs and Preferences of Patients With Head-neck Cutaneous SCC

Squamous Cell Carcinoma of the Head and Neck | Squamous Cell Carcinoma of Head and Neck | Skin Cancer | Patient Satisfaction | Decision Making | Squamous Cell Carcinoma | Cutaneous Squamous Cell Carcinoma of the Head and Neck | Cutaneous Squamous Cell Carcinoma | High-Risk Cancer | Preference, Patient | I...

Netherlands
German Breast Group
Celgene Corporation; Amgen

Completed

Denosumab as an add-on Neoadjuvant Treatment (GeparX) (GeparX)

Inflammatory Breast Cancer | HER2 Positive Breast Cancer | Tubular Breast Cancer Stage II | Mucinous Breast Cancer Stage II | Breast Cancer Female NOS | Invasive Ductal Breast Cancer | Tubular Breast Cancer Stage III

Germany
Tocagen Inc.

Terminated

A Study of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Patients With Solid Tumors or Lymphoma (Toca 6)

Melanoma | Sarcoma | Lymphoma | Head and Neck Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Bladder Cancer | Triple Negative Breast Cancer | IDH1 Mutated Solid Tumors | IDH1 Mutated or MGMT Methylated Recurrent HGG (Not Recruiting)

United States
Institut Curie

Completed

Prospective Evaluation of a Program for Early Identification of Needs and Multidisciplinary Intervention in Supportive Care in Digestive Oncology (DParcoursDig)

Non-colorectal Cancer (Esophagus, Stomach, Liver/Bile Ducts, Pancreas, Neuroendocrine Carcinoma) | Colorectal With Associated Risk Factors

France
Tasca Therapeutics

Recruiting

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

Non-Small Cell Lung Cancer | Bladder Cancer | Colorectal Carcinoma | Solid Tumor Malignancies | Pancreatic Cancer, Advanced or Metastatic | Head and Neck (HNSCC) | Small Cell Lung Cancer ( SCLC )

United States
Pinnacle Biologics Inc.

Withdrawn

Efficacy and Safety of a Sunscreen Against Porfimer Sodium-induced Phototoxicity to Visible Light

Esophageal Cancer | Non Small Cell Lung Cancer | High-grade Dysplasia in Barrett Esophagus

Clinical Trials on High-Risk Non-Muscle-Invasive Bladder Cancer

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