Clinical Trials on Optimal SpO2 Value

Total 3636 results

Centro Cardiologico Monzino
Azienda Ospedaliera "Sant'Andrea"; Azienda Sanitaria Universitaria Giuliano...

Recruiting

Exercise Oxygen Kinetic and Cardiac Output in Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy | Cardiopulmonary Exercise Test | Cardiac Output Measurement

Italy
University Hospital, Bordeaux
Amicus Therapeutics; Fédération Française de Cardiologie; Fondation Bordeaux...

Completed

Assessment of the Relations Between Endothelial and Venous Dysfunctions and Left Ventricular Obstruction in Genetic Hypertrophic Cardiomyopathies (HCM-Vein)

Endothelial Dysfunction | Hypertrophic Cardiomyopathy

France
Universitätsklinikum Hamburg-Eppendorf
The German Heart Foundation; Deutsches Zentrum für Herz-Kreislauf-Forschung...

Active, not recruiting

Randomized Trial of TAVI vs. SAVR in Patients With Severe Aortic Valve Stenosis at Low to Intermediate Risk of Mortality (DEDICATE)

Aortic Valve Stenosis

Germany
University of Virginia

Active, not recruiting

Perfusion Abnormalities in Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy (HCM)

United States
Cytokinetics
Sanofi; Bayer

Active, not recruiting

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic nHCM (ACACIA-HCM)

Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy

United States, Israel, Spain, Denmark, Japan, Iceland, China, France, Canada, United Kingdom, Brazil, Australia, Netherlands, Greece, Hungary, Portugal, Germany, Argentina, Italy, Poland
Universitaire Ziekenhuizen KU Leuven
University Hospital, Antwerp; AZ Delta

Completed

COronary and MICrocirculatory Measurements in Patients With Aortic Valve Stenosis. (COMIC-AS)

Coronary Artery Disease | Aortic Stenosis

Belgium
Sahlgrenska University Hospital

Enrolling by invitation

Artificial Intelligence in New Cardiac MR Markers for Congenital Heart Disease (AI-CMR)

Aortic Valve Disease | Magnetic Resonance Imaging | Child, Only | Risk Stratification | Pulmonary Valve Disease

Sweden
Imperial College London
The Leeds Teaching Hospitals NHS Trust; Guy's and St Thomas' NHS Foundation... and other collaborators

Active, not recruiting

Prospective Evaluation Of Exercise-Induced Cardiac Conduction Instability In Predicting Ventricular Fibrillation Events In Hypertrophic Cardiomyopathy (PREDICTVFII)

Hypertrophic Cardiomyopathy

United Kingdom
Cytokinetics

Completed

A Single and Multiple Ascending Dose Study of CK-3773274 in Healthy Adult Subjects

Healthy Subjects | Symptomatic Obstructive Hypertrophic Cardiomyopathy

United States
CHU de Reims

Completed

Cardiac Amyloidosis Prevalence and Outcome in Aortic Stenosis Patients Undergoing Transcatheter Aortic Valve Implantation (CAMPOS-TAVI)

Aortic Stenosis

France
Ya-Wei Xu

Completed

Prognostic Significance of CMD Assessed by IMR in HCM Patients (caIMR-HCM)

Coronary Cicrovascular Dysfunction | Hypertrophic Cardiomyopathy Patients
University of Leicester

Completed

Role of Elastin Metabolites in Aortic Remodelling in AS (ELASTIC-AS)

Aortic Stenosis

United Kingdom
Xijing Hospital

Active, not recruiting

Impact of Liwen Procedure in Obstructive Hypertrophic Cardiomyopathy on Arrhythmias

Arrhythmia | Hypertrophic Cardiomyopathy

China
Medical University of Graz

Terminated

Effect of TF-TAVR on Emotional Status, Quality of Life, Frailty and Inflammation

Depression | Inflammation | Aortic Valve Stenosis | Frail Elderly Syndrome | Clinical Trial

Austria
Tufts Medical Center

Completed

Clinical and Therapeutic Implications of Fibrosis in Hypertrophic Cardiomyopathy

Myocardial Fibrosis | Hypertrophic Cardiomyopathy

United States
Mayo Clinic
Sanofi; National Institutes of Health (NIH)

Completed

A Study Evaluating the Effects of Ataciguat (HMR1766) on Aortic Valve Calcification (CAVS)

Aortic Valve Stenosis

United States
Royal Brompton & Harefield NHS Foundation Trust
Acutus Medical

Unknown

HCM-AF Ablation With ACUTUS

Atrial Fibrillation | Hypertrophic Cardiomyopathy
Hospital Clinic of Barcelona

Unknown

CArdiac Desynchronization In Obstructive HCM, CARDIO-HCM (CARDIO-HCM)

Hypertrophic Obstructive Cardiomyopathy (HOCM)

Spain
Institute of Cardiology, Warsaw, Poland

Completed

Antiarrhythmic Therapy Versus Catheter Ablation for Atrial Fibrillation in Hypertrophic Cardiomyopathy

Atrial Fibrillation | Hypertrophic Cardiomyopathy

Poland
Insel Gruppe AG, University Hospital Bern
University Hospital, Basel, Switzerland; Cardiocentro Ticino; Triemli Hospital

Recruiting

Prediction of Reverse Remodeling and Outcome in Patients With Severe Secondary Mitral Valve Regurgitation Undergoing Transcatheter Edge-to-edge Mitral Valve Repair (PRE-MITRA)

Severe Mitral Regurgitation

Switzerland
Asan Medical Center
Daewoong Pharmaceutical Co. LTD.

Active, not recruiting

Enavogliflozin Outcome Trial in Functional Tricuspid Regurgitation (EVENT)

Heart Failure With Preserved Ejection Fraction | Tricuspid Regurgitation

South Korea
Hospices Civils de Lyon

Withdrawn

Effectiveness and Safety of Mitral Valve Repair With the NeoChord DS1000 Artificial Chordae Delivery System Versus Conventional Surgery in Patients With Severe Primary Mitral Regurgitation Due to Isolated Leaflet Prolapse (MITRACHORD)

Cardiovascular Diseases

France
Samsung Medical Center

Recruiting

Efficacy of Early Rhythm Control in AF With TR Patients (TRAF)

Atrial Fibrillation (AF) | Tricuspid Regurgitation (TR)

South Korea
First People's Hospital of Hangzhou
Second Affiliated Hospital, School of Medicine, Zhejiang University

Recruiting

Cardiac Synchronization and Tricuspid Regurgitation With Leadless Pacemaker (MICRA-SYNK)

Bradycardia

China
LMU Klinikum
Heart Center Leipzig - University Hospital; Deutsches Zentrum für Herz-Kreislauf-Forschung... and other collaborators

Active, not recruiting

TRICuspid Intervention in Heart Failure Trial (TRIC-I-HF)

Heart Failure Attributable to Severe Tricuspid Regurgitation

Germany
Ancora Heart, Inc.

Completed

Feasibility of the AccuCinch® System for Left Ventricular Reshaping of the Mitral Apparatus to Reduce Functional Mitral Regurgitation and Improve Left Ventricular Function (LVRECOVER)

Severe Functional Mitral Regurgitation and Heart Failure

Australia
Duke University
National Heart, Lung, and Blood Institute (NHLBI); Heart Failure Clinical Research...

Terminated

Effectiveness of Surgical Mitral Valve Repair Versus Medical Treatment for People With Significant Mitral Regurgitation and Non-ischemic Congestive Heart Failure (SMMART-HF)

Heart Failure | Mitral Valve Insufficiency

United States, Canada
Oulu University Hospital

Terminated

Remote Ischemic Preconditioning in Patients Undergoing Isolated Aortic Valve Replacement Surgery

Myocardial Ischemia | Aortic Valve Disease

Finland
Meshalkin Research Institute of Pathology of Circulation

Completed

Flexible Band vs Rigid Ring for Degenerative Mitral Valve Disease

Mitral Regurgitation
Shaare Zedek Medical Center

Completed

Repair of Ischemic Mitral Regurgitation: Comparison Between Flexible and Rigid Annuloplasty Rings (IMR2)

Mitral Regurgitation

Israel
Vitor Emer Egypto Rosa
Fundação de Amparo à Pesquisa do Estado de São Paulo

Recruiting

Effect of Losartan on the Neurohumoral Axis and Ventricular Remodeling of Patients With Severe Aortic Regurgitation Undergoing Valve Surgery. (ARBNP)

Heart Valve Diseases | Natriuretic Peptide, Brain | Aortic Regurgitation Disease | Left Ventricle Remodeling | Heart Failure Congestive

Brazil
China National Center for Cardiovascular Diseases

Recruiting

Concomitant Hybrid Versus Catheter Ablation for Atrial Fibrillation With Hypertrophic Cardiomyopathy

Atrial Fibrillation | Cardiomyopathy, Hypertrophic | Radiofrequency Ablation

China
University of Aarhus
Aarhus University Hospital

Recruiting

Effect of Dapagliflozin on Myocardial and Renal Function Following Aortic Valve Stenosis Intervention (DAPAS)

Aortic Stenosis | Left Ventricle Hypertrophied

Denmark
University of Zurich

Active, not recruiting

Optimal Timing of Transcatheter Aortic Valve Implantation and Percutaneous Coronary Intervention - The TAVI PCI Trial (TAVI-PCI)

Coronary Artery Disease | Aortic Stenosis | PCI | TAVI

Switzerland, France, Germany, Netherlands, Austria, Italy
GCS Ramsay Santé pour l'Enseignement et la Recherche
Euraxi Pharma

Terminated

Predictive Value of Pre-TAVI Infrahissian Conduction Time in the Occurrence of Complete Atrioventricular Block (TAVHIS)

Aortic Stenosis, Severe

France
Prolaio

Completed

A Noninterventional, Single-Center Feasibility Study to Evaluate Measures of Heart Failure Risk

Heart Failure | Cardiomyopathy, Hypertrophic | Left Ventricular Hypertrophy

United States
Tongji Hospital

Completed

Anesthetic Management for TA-BSM in HOCM

Anesthesia | Hypertrophic Cardiomyopathy | Transapical Beating-heart Septal Myectomy

China
Michele De Bonis

Completed

Use of Cryoenergy to Faciltate Myectomy in Hypertrophic Obstructive Cardiomyopathy: Comparison With the Classical Approach

Obstructive Hypertrophic Cardiomyopathy | Septal Hypertrophy

Italy
Seoul National University Hospital

Completed

A Feasibility Study to Evaluate the Safety and Short-term Effectiveness of Transcatheter Pulmonary Valve (TPV)

Cardiovascular Abnormalities | Pulmonary Valve Insufficiency | Pulmonary Valve Stenosis | Congenital Heart Defects

Korea, Republic of
Henry Ford Health System

Completed

Remote Ischemic Preconditioning for Renal Protection in TAVI

Renal Insufficiency | Aortic Valve Stenosis | Contrast-induced Nephropathy

United States
Rabin Medical Center

Completed

Acute STROke Complicating TAVI - Management and Outcomes (ASTRO-TAVI)

Stroke | Aortic Valve Stenosis | Periprocedural Complication

Israel
MyoKardia, Inc.

Completed

A Phase 2 Open-label Pilot Study Evaluating MYK-461 in Subjects With Symptomatic Hypertrophic Cardiomyopathy and Left Ventricular Outflow Tract Obstruction (PIONEER-HCM)

Cardiomyopathy, Hypertrophic Obstructive | Left Ventricular Outflow Tract Obstruction

United States
University of Texas Southwestern Medical Center
Mid America Heart Institute

Withdrawn

Targeted Testing for ATTR Among Aortic Stenosis Patients-Pilot

Aortic Valve Stenosis | Cardiac Amyloidosis
IRCCS San Raffaele
Menarini International Operations Luxembourg SA

Completed

Effects of Ranolazine on Coronary Microvascular Dysfunction in Patients With Hypertrophic Cardiomyopathy

HCM - Hypertrophic Non-Obstructive Cardiomyopathy

Italy
Xijing Hospital

Unknown

Risk Factors of Postoperative Complications in HCM Patients (RFHCM)

Hypertrophic Obstructive Cardiomyopathy

China
Emory University

Completed

Follow Up on Freestyle Valves in Children

Pulmonary Valve Stenosis | Right Ventricle | Pulmonary Valve Atresia

United States
Oslo University Hospital

Unknown

Severe Aortic Stenosis in Patients Referred for Valve Surgery (SAS)

Aortic Stenosis | Valvular Heart Disease | Symptomatic Aortic Stenosis

Norway
Tomsk National Research Medical Center of the Russian...

Recruiting

Study of Treatment of Thoracic Aortic Aneurysms and Dilatation in Combination With Tricuspid and Bicuspid Aortic Valves.

Ascending Aorta Aneurysm | Dilation of the Ascending Aorta

Russian Federation
University of Edinburgh

Completed

Assessment of Risk in Thoracic Aortopathy Using 18F-Sodium Fluoride (AoRTAS)

Bicuspid Aortic Valve | Aortic Dissection | Thoracic Aortic Aneurysm

United Kingdom
Caption Health, Inc.

Recruiting

Point-of-Care Echocardiography in Patients with Known or Suspected Aortic Stenosis (POC)

Patients with an Indication for an Echocardiographic Examination with Suspicion of Valcular Heart Disease

United States

Clinical Trials on Optimal SpO2 Value

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