Clinical Trials on Program Development

Total 5498 results

DePuy International

Terminated

A Single Centre Study to Assess the Long-term Performance of the Pinnacle™ Cup With a Ceramic-on-ceramic Bearing in Primary Total Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Traumatic Femoral Fractures | Nonunion of Femoral Fractures

Czech Republic
DePuy International

Terminated

A Two Centre Study to Assess the Long-term Performance of the Pinnacle™ Cup With a Metal-on-Metal Bearing in Primary Total Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Traumatic Femoral Fractures | Nonunion of Femoral Fractures

United Kingdom, Italy
DePuy International

Terminated

A Multi-centre Study to Assess the Long-term Performance of the Summit™ Hip in Primary Total Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Traumatic Femoral Fractures | Nonunion of Femoral Fractures

China, Hong Kong, Italy, Korea, Republic of, New Zealand
Hacettepe University

Recruiting

This Study Aims to Evaluate the Effect of Rinsing Off or Blot-drying Silver Fluoride on the Retention of Subsequently-applied Resin- and Glass Ionomer-based Fissure Sealants in Permanent Molars Affected by Molar-Incisor Hypomineralization.

Dental Caries | Children | Molar Incisor Hypomineralisation

Turkey
BioMarin Pharmaceutical

Recruiting

A Multicenter Multinational Observational Study of Children With Hypochondroplasia

Hypochondroplasia

United States, France, Spain, Canada, Germany, Italy, Japan, Australia, Argentina, Brazil, United Kingdom
Sheffield Children's NHS Foundation Trust
EOS imaging Inc.

Not yet recruiting

Can EOS Hip Imaging Replace CT Hip Scans? (EOS)

Hip Dysplasia | Femoroacetabular Impingement
Hospices Civils de Lyon

Recruiting

Burosumab and 1-25 (OH) Vitamin D on Human Osteoblasts (HYPO-BLASTES)

Craniosynostoses

France
BioMarin Pharmaceutical

Enrolling by invitation

Long-Term Extension Study of Vosoritide to Treat Children With Hypochondroplasia (CANOPY-HCH-EXT)

Hypochondroplasia

United States, Australia, France, United Kingdom, Japan, Italy, Germany, Canada, Spain
Children's Hospital Medical Center, Cincinnati

Active, not recruiting

Comprehensive Study of Post-surgical Pain After Pectus or Spine Surgery

Pain, Postoperative | Scoliosis Idiopathic | Excavatum, Pectus

United States
Marmara University

Completed

The Relationship Between Developmental Level in Infancy and Preschool Motor Performance in Risky Infants

Cerebral Palsy | Developmental Coordination Disorder

Turkey
National Human Genome Research Institute (NHGRI)

Completed

Clinical Study of Muenke Syndrome (FGFR3-Related Craniosynostosis)

Craniosynostosis | Muenke Syndrome

United States
University of South Florida
National Institutes of Health (NIH); Rare Diseases Clinical Research Network

Completed

Pregnancy in Osteogenesis Imperfecta (OI) Registry

Osteogenesis Imperfecta | Brittle Bone Disorders

United States
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Pasireotide LAR (Long-acting Release) in Japanese Patients With Acromegaly or Pituitary Gigantism

Acromegaly | Pituitary Gigantism

Japan
Eunice Kennedy Shriver National Institute of Child...

Terminated

Free Fatty Acids, Body Weight, and Growth Hormones Secretion in Children

Obesity | Growth Hormone Deficiency | Short Stature

United States
National Institute of Dental and Craniofacial Research...

Completed

Bone Marrow Injection to Replace Diseased Bone in Polyostotic Fibrous Dysplasia and McCune-Albright Syndrome

Polyostotic Fibrous Dysplasia

United States
Luca Sangiorgi

Recruiting

Registry of Osteogenesis Imperfecta (ROI)

Osteogenesis Imperfecta

Italy
Eunice Kennedy Shriver National Institute of Child...

Completed

Evaluation and Intervention for the Effects of Osteogenesis Imperfecta

Osteogenesis Imperfecta

United States
BioMarin Pharmaceutical

Active, not recruiting

An Extension Study to Evaluate Safety and Efficacy of BMN 111 in Children With Achondroplasia

Achondroplasia

United States, Australia, Japan, United Kingdom
BioMarin Pharmaceutical

Active, not recruiting

A Clinical Trial to Evaluate Safety of Vosoritide in At-risk Infants With Achondroplasia

Achondroplasia

Australia, United Kingdom
Tamas Vegh, MD

Enrolling by invitation

Measuring of the Duration of Action of Different Doses of Rocuronium-induced Neuromuscular Block in Infants During Surgical Treatment of Craniosynostosis

Residual Neuromuscular Block | Neuromuscular Blocking Agents | Neuromuscular Blockade Monitoring

Hungary
Columbia University
Tercica

Terminated

Differential Effects of rhGH vs. rhIGF-1 on Cardiovascular Risk Factors

Growth Hormone Deficiency

United States
CENTOGENE GmbH Rostock

Withdrawn

Biomarker for Creatine Deficiency Syndromes (BioCDS) (BioCDS)

Intellectual Disability | Developmental Delay | Intractable Epilepsy | Movement Disorder | Behavioral Disorder

India, Sri Lanka, Egypt
B.P. Koirala Institute of Health Sciences

Completed

Height Versus Height and Weight Based Spinal Bupivacaine on Maternal Haemodynamics for Elective Cesarean in Short Stature Patients

Maternal Hypotension After Spinal Anesthesia

Nepal
Pfizer

Completed

Patient Perception of Treatment Burden in Weekly Versus Daily Growth Hormone Injections in Children With GHD

Growth Hormone Deficiency

United States, United Kingdom, Bulgaria, Czechia, Slovakia
Cairo University

Unknown

Hypo-mineralization of Primary and Permanent Teeth in a Group of Children With Stunted Growth.A Cross Sectional Study.

Hypomineralization of Enamel | Hypomineralization Molar Incisor | Short Stature

Egypt
Pfizer

Completed

A Prospective Non-Interventional Study Protocol With Primary Data Collection - Assessment Of The Long Term Treatment Outcomes Of Genotropin Treatment In Growth Hormone Deficiency (GHD) Patients

Growth Hormone Deficiency

Sweden
Genentech, Inc.

Completed

A Post-Marketing Study of the Immunogenicity of Somatropin (Ribosomal Deoxyribo Nucleic Acid [rDNA] Origin) Injection (Nutropin AQ®) in Children With Growth Hormone Deficiency

Growth Hormone Deficiency

United States
Nationwide Children's Hospital

Completed

Repeated Infusions of Mesenchymal Stromal Cells in Children With Osteogenesis Imperfecta (STOD3)

Osteogenesis Imperfecta Type III | Osteogenesis Imperfecta Type II

United States
Phage Pharmaceuticals, Inc.

Completed

Safety Study of Syntropin (Human Growth Hormone) for the Treatment of Growth Hormone Deficiency

Growth Hormone Deficiency

United States
Genentech, Inc.

Completed

National Cooperative Growth Study (NCGS) of Optimal Nutropin AQ and Nutropin Dosing in Pubertal Growth Hormone-Deficient (GHD) Patients

Dwarfism, Pituitary

United States
McGill University

Unknown

Randomized Clinical Trial of Phonological Interventions (ECRIP)

Dyslexia | Developmental Articulation Disorder | Speech Articulation Disorder | Phonological Impairment

Canada
Shanghai Jiao Tong University School of Medicine

Not yet recruiting

Comparisons of Different Forms of Glucocorticoid on the Recovery of Reproductive Function in Patients With 21α-hydroxylase Deficiency (CGP21)

Congenital Adrenal Hyperplasia

China
Northwestern University
Chicago Run; American Academy of Cerebral Palsy and Developmental Medicine; Spencer...

Enrolling by invitation

Ready, Set, Go! A Physical Fitness Intervention for Children With Mobility Challenges

Cerebral Palsy | Gross Motor Development Delay | Motor Skills Disorders | Myelomeningocele | Arthrogryposis

United States
Diurnal Limited
National Institutes of Health (NIH)

Withdrawn

Open-label Comparison of Chronocort® Versus Standard Glucocorticoid Replacement Therapy (RESTORE)

Congenital Adrenal Hyperplasia

United States
Region Stockholm

Enrolling by invitation

Effects and Importance of Epinephrine/Adrenalin Deficiency in CAH

Congenital Adrenal Hyperplasia

Sweden
Ain Shams University

Unknown

Final Height in Patients With CAH

Congenital Adrenal Hyperplasia
Indiana University

Completed

Acamprosate in Youth With Fragile X Syndrome

Fragile X Syndrome | Autism Spectrum Disorders

United States
University of North Carolina, Chapel Hill

Completed

Brain Connectivity in Neurodevelopmental Disorders in Response to Treatment

Fragile X Syndrome | Psychosis | Autism Spectrum Disorders

United States
Boston Children's Hospital

Completed

Dexamethasone Treatment of Congenital Adrenal Hyperplasia

Adrenal Hyperplasia, Congenital

United States
University of North Carolina, Chapel Hill
National Institute on Minority Health and Health Disparities (NIMHD)

Not yet recruiting

Personalized Care for Prenatal Stress Reduction & Prevention of Preterm Birth (PTB) Disparities (PTBCARE+)

Stress | Pregnancy Complications | Pregnancy | Preterm Birth | Preeclampsia | Emotional Stress | Cervical Insufficiency | Care Coordination | Resilience, Psychological | Cervical Shortening | Disparities | Preterm Birth Complication | Prenatal Care | Pregnancy Induced Hypertension | Preeclampsia (PE) | Neonates and Preterm... and other conditions

United States
Yun Liu,PhD

Recruiting

Development and Application of a Diagnosis and Treatment System for Children's Brain Diseases Based on Knowledge Graphs and Large Models

Cerebral Palsy | Attention Deficit Hyperactivity Disorder | Mental Retardation | Tourette's Syndrome | Autism Spectrum Disorders

China
University Hospital, Toulouse

Recruiting

Autistic Symptomatology and Sensory Profile in Children With Prader-Willi Syndrome (CASSPER)

Prader-Willi Syndrome

France
Krystal Parker, PhD

Recruiting

Cerebellar Stimulation and Cognitive Control

Depression | Schizophrenia | Parkinson Disease | Bipolar Disorder | Autism Spectrum Disorder

United States
Boston Children's Hospital

Enrolling by invitation

A Safety and Feasibility Trial Protocol of Metformin in Infants After Perinatal Brain Injury

Hypoxic-Ischemic Encephalopathy | Infant Development | Neurodevelopment | HIE

United States
Elizabeth Kilbey
Braingaze

Active, not recruiting

Exploring Eye Vergence Markers ADHD) and ASD

Attention Deficit Hyperactivity Disorder (ADHD) | Autism Spectrum Disorder (ASD)

Spain, United Kingdom
Dairy Goat Co-operative (N.Z.) Limited
Chulalongkorn University

Active, not recruiting

Transition to Infant Formula Feeding on Gastrointestinal Regurgitation (TIGER) Study (TIGER)

Constipation - Functional | Infant Development | Gastrointestinal Disorder, Functional | Colic, Infantile | Regurgitation, Gastric

Thailand
Vanda Pharmaceuticals

Completed

Study of the Pharmacokinetics and Safety of Tasimelteon in Children and Adolescents

Autism Spectrum Disorder | Smith-Magenis Syndrome | Non-24 Hour Sleep-Wake Disorder | Circadian Rhythm Sleep Disorders

United States
University Hospital, Clermont-Ferrand

Completed

Predictive Values of Plasma Soluble RAGE Levels and RAGE Polymorphisms for the Onset of Acute Respiratory Distress Syndrome in Critically Ill Patients (PrediRAGE)

Intensive Care Unit | Population at High Risk for ARDS Development

France
Haukeland University Hospital

Unknown

Continuous Subcutaneous Hydrocortisone Infusion in Congenital Adrenal Hyperplasia (CAH)

Adrenal Hyperplasia, Congenital

Norway
Maria I. New
National Center for Research Resources (NCRR); Office of Rare Diseases (ORD)

Completed

Examining Genetic Differences Among People With 21-Hydroxylase Deficiency

21-hydroxylase Deficiency

United States, Brazil

Clinical Trials on Program Development

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Slovakia

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Rare Diseases

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