Search clinical trials for: Dose decrease

Total 7787 results

McGill University Health Centre/Research Institute...
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Teen Adherence in KidnEy Transplant Improving Tracking To Optimize Outcomes - Stage 3

Medication Adherence | Kidney Transplantation

Canada, United States
Portola Pharmaceuticals

Completed

An Open-Label, Single-Dose, Mass-Balance Study to Assess the Disposition of 14C-Labeled PRT054021 in Healthy Male Subjects

Health Volunteers
Xinhua Hospital, Shanghai Jiao Tong University...

Completed

Iron-fortified Parenteral Nutrition in the Prevention and Treatment of Anemia in Premature Infants

Premature Birth

China
Bristol-Myers Squibb

Completed

To Assess the Effect of Renal Impairment on the Blood Levels of Daclatasvir (DCV), Asunaprevir (ASV) and BMS-791325 After Multiple Doses of a Fixed Dose Combination Tablet

Hepatitis C

United States
AFT Pharmaceuticals, Ltd.

Not yet recruiting

A Study of Combogesic® IV (Intravenous) in Pediatric Patients With Acute Pain

Acute Pain

United States
Ain Shams University

Not yet recruiting

Intravenous Tranexamic Acid (TXA)

Bleeding | Obese Patients | Obese Patients With Bariatric Surgery

Saudi Arabia
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Recruiting

Low-dose Radiotherapy Combined With Chemotherapy and AK112 as Second-line Treatment in Patients With Advanced G/GEJ Cancer

Gastric Cancer

China
University Hospital, Caen
University Hospital, Rouen

Completed

Apixaban in Subjects With Peritoneal Dialysis (ApiDP)

Peritoneal Dialysis | Chronic Renal Insufficiency

France
West China Hospital

Completed

Low-dose Radiotherapy Plus Tislelizumab in Combination With Afatinib for Neoadjuvant Treatment of Surgically Resectable Head and Neck Squamous Carcinoma

Head and Neck Cancer

China
University Health Network, Toronto

Terminated

A Study of Various Treatments in Serous or p53 Abnormal Endometrial Cancer (CAN-STAMP)

Endometrial Carcinoma | P53 Mutation | Serous Carcinoma

Canada
Sun Yat-sen University
First Affiliated Hospital, Sun Yat-Sen University; Red Cross Hospital, Hangzhou... and other collaborators

Active, not recruiting

Metformin Hydrochloride and Empagliflozin Tablets in the Treatment of Type 2 Diabetes

Type 2 Diabetes

China
Technische Universität Dresden
Masaryk University; University Hospital Dresden

Completed

Comparison Between Two Dose Levels of Daunorubicin and Between One vs. Two Induction Cycles for Adult Patients With AML (DaunoDouble)

Leukemia, Myelocytic, Acute

Germany, Czechia
Fox Chase Cancer Center

Withdrawn

Sotorasib in KRAS G12C Mutated, Resectable, Stage Ib-IIIA NSCLC

Non-Small Cell Lung Cancer

United States
Rush University Medical Center

Withdrawn

Single Versus Multi-Dose Oral Tranexamic Acid in Patients at High Risk for Blood Transfusion After Total Joint Arthroplasty

Arthritis | Anemia | Total Knee Arthroplasty | Total Hip Arthroplasty

United States
Oregon Health and Science University
National Trauma Research Institute; Medical Research Foundation, Oregon

Completed

Thrombelastography Based Dosing of Enoxaparin

Thromboembolic Complications

United States
National Institute on Drug Abuse (NIDA)

Completed

An Hepatitis B Vaccine Model for HIV Vaccine Trials in Drug Users

HIV Infection | Hepatitis B Infection | Hepatitis C Infection

United States
Xiao Li

Unknown

Efficacy Study of CHG Regimen vs Decitabine to Treat Higher-risk MDS

Myelodysplastic Syndromes

China
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Sun Yat-sen University; Guangzhou First... and other collaborators

Unknown

MSCs Combined With CD25 Monoclonal Antibody and Calcineurin Inhibitors for Treatment of Steroid-resistant aGVHD

Acute Graft-versus-host Disease

China
University of Regensburg
Novartis Pharmaceuticals

Unknown

CNI-free "Bottom"-up Immunosuppression in Patients Undergoing Liver Transplantation (BUILT_01)

Liver Transplantation | Renal Impairment | Everolimus

Germany
Actavis Inc.

Completed

A Relative Bioavailability Study of Glyburide/Metformin HCl 5 mg/500 mg Tablets Under Fasting Conditions

Healthy

United States
Hadassah Medical Organization
Jerusalem Institute for Child Development

Unknown

Trial of Low-Dose Naltrexone for Children With Pervasive Developmental Disorder (PDD)

Pervasive Developmental Disorder

Israel
GlaxoSmithKline
Crucell Holland BV; The PATH Malaria Vaccine Initiative (MVI)

Completed

Safety, Immunogenicity and Efficacy Against of a Combined Malaria Vaccine in Healthy Malaria-naïve Adults

Malaria

United States
H. Lee Moffitt Cancer Center and Research Institute
Clinigen, Inc.

Recruiting

IL2 With Ipilimumab Followed by Nivolumab in Stage 3 or 4 Melanoma Patients

Melanoma Stage IV | Melanoma Stage III | Inoperable Disease

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Terminated

Amifostine and Melphalan in Treating Patients With Primary Systemic Amyloidosis Who Are Undergoing Peripheral Stem Cell Transplantation

Multiple Myeloma and Plasma Cell Neoplasm | Drug/Agent Toxicity by Tissue/Organ

United States
Masonic Cancer Center, University of Minnesota

Active, not recruiting

MT2017-45: CAR-T Cell Therapy for Heme Malignancies

Acute Lymphoblastic Leukemia | Large B-cell Lymphoma

United States
Xi'an Xintong Pharmaceutical Research Co.,Ltd.

Not yet recruiting

A Randomized, Double-blind, Single-center Phase I/IIa Study of XTYW007 Tablets in Subjects.

Non-Alcoholic Fatty Liver Disease

China
Mahidol University
Thai AIDs society

Recruiting

Efficacy and Safety of Low-Dose Colchicine on Surrogate Markers of Cardiovascular Events in People Living With HIV Receiving Antiretroviral Therapy

HIV Infections | Inflammatory Markers | Colchicine Adverse Reaction

Thailand
Duke University
Merck Sharp & Dohme LLC

Withdrawn

Trimodality Approach of Low Dose iOnizing Radiation With or Without Neoadjuvant Pembrolizumab and Prostatectomy for Men With Intermediate/High Risk Prostate Cancer (TALON) (TALON)

Prostate Cancer

United States
Gregory Daniels
Immunotherapy Foundation

Terminated

Adoptive Cell Transfer of Autologous Tumor Infiltrating Lymphocytes and High-Dose Interleukin 2 in Select Solid Tumors

Metastatic Melanoma | Metastatic Head and Neck Cancer | Locally Advanced Refractory/Recurrent Melanoma | Locally Advanced Refractory/Recurrent Head and Neck Cancer

United States
Johnson & Johnson Private Limited

Completed

A Study to Assess Safety of Canagliflozin and Metformin Hydrochloride Combination Given as a Supplement to Diet and Exercise to Improve Blood Sugar Level in Indian Adult Participants With Diabetes

Diabetes Mellitus

India
Georgetown University
Abbott

Terminated

ABT-888 and Temozolomide for Liver Cancer

Hepatocellular Carcinoma

United States
Tang-Du Hospital

Active, not recruiting

Neoadjuvant PD-1 Inhibitor (Sintilimab), Anlotinib Combined With Chemotherapy in Resectable Stage IIA-IIIB NSCLC

Lung Cancer | Chemotherapy | Sintilimab | Anlotinib

China
Karolinska Institutet

Completed

Dosing of Thromboprophylaxis and Mortality in Critically Ill COVID-19 Patients

Covid19 | Thromboembolism

Sweden
Hepatopancreatobiliary Surgery Institute of Gansu...

Completed

Radiofrequency-assisted Liver Resection in Intractable Liver Cancer

Liver Cancer

China
University of Texas Southwestern Medical Center

Withdrawn

Vitamin C for Severe Thermal Injuries

Severe Thermal Injury, Greater Than 20% TBSA

United States
University Hospital, Strasbourg, France

Terminated

Efficacy of Metformin in Achieving Glycaemia Goals as Recommended for the Treatment of Gestational Diabetes in Non Obese Women

Oxidative Stress | Gestational Diabetes | Treatment | Metformin

France
Novartis Pharmaceuticals

Completed

Dose-ranging Safety and Tolerability Study in Subjects ≥60 Years of Age

Alzheimer's Disease

Netherlands, United States, Belgium, Germany, United Kingdom
University of Miami

Terminated

Cetuximab + Taxotere With Low Dose Fractionated Radiation for Head and Neck Carcinoma

Head and Neck Cancer | Recurrent Disease | Squamous Cell Carcinoma

United States
Seoul National University Hospital

Completed

The Effect of High Dose Vitamin C on the Liver Function in Chronic Hepatitis Patients

Chronic Hepatitis C | Chronic Hepatitis | Chronic Alcoholic Hepatitis

Korea, Republic of
University of Wisconsin, Madison

Completed

Use of High-resolution Manometry to Detect Upper Airway Obstruction During Sleep

Obstructive Sleep Apnea

United States
University Hospitals Cleveland Medical Center

Completed

Reparel Knee Sleeve vs. TED Hose for Post-op Swelling, Pain and Range of Motion After Total Knee Replacement

Osteoarthritis Knees Both

United States
Hospital Regional Dr. Rafael Estévez
Complejo Hospitalario Dr. Arnulfo Arias Madrid; Hospital Santo Tomas; Hospital... and other collaborators

Completed

Use of Multiple Doses of Convalescent Plasma in Mechanically Intubated Patients With COVID-19

COVID-19

Panama
Boehringer Ingelheim

Completed

Safety, Pharmacodynamics, and Pharmacokinetics of BIBT 1011 BS in Healthy Subjects

Healthy
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Clofarabine and High-Dose Melphalan Followed by Donor Stem Cell Transplant in Patients With Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, or Myelodysplastic Syndromes

Myelodysplastic Syndromes | Leukemia

United States
The Hospital for Sick Children
Society for Pediatric Dermatology

Completed

Pulse Steroids Versus Oral Steroids in Problematic Hemangiomas of Infancy

Hemangiomas

Canada
Baoping XU

Recruiting

Research on the Treatment of Severe Community-acquired Pneumonia in Children

Severe Pneumonia

China
National Cancer Institute (NCI)

Terminated

RO4929097 And Exemestane in Treating Pre- and Postmenopausal Patients With Advanced or Metastatic Breast Cancer

Stage IV Breast Cancer | Recurrent Breast Carcinoma | Stage IIIB Breast Cancer | Stage IIIC Breast Cancer | Estrogen Receptor Positive | HER2/Neu Negative | Male Breast Carcinoma

United States
Centre Hospitalier Universitaire de Nīmes

Completed

MIROCALS: Modifying Immune Response and OutComes in ALS (MIROCALS)

Amyotrophic Lateral Sclerosis

France, United Kingdom
KIST Medical and Teaching Hospital
Nepal Health Research Council

Completed

Comparative Analytical Study of Intravenous Bolus Dose of Mephentermine and Phenylephrine for Hemodynamic Stability During Elective Cesarean Section Under Spinal Anesthesia at KIST Medical College and Teaching Hospital

Hemodynamic Stability

Nepal
University of Tennessee

Withdrawn

Aspirin (ASA) Therapy and Preeclampsia Prevention

Preeclampsia

United States

Search clinical trials for: Dose decrease

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