Search clinical trials for: Dose decrease

Total 7785 results

Hospital Universitari Vall d'Hebron Research Institute

Recruiting

Study to Compare the Outcome of Receiving Continued Immunosuppression Versus Stopping Immunosuppression at 6 Months to Safely Prevent Human Leukocyte Antigen (HLA) Sensitization in Patients With Late Renal Graft Failure

Graft Rejection | Renal Failure Chronic Requiring Dialysis | Graft Failure | Allograft | Renal Failure , Chronic

Spain
German Oncology Center, Cyprus

Recruiting

Artificial Intelligence to Personalize Prostate Cancer Treatment (the HypoElect Trial) (HypoElect)

Prostate Cancer

Cyprus
Tata Memorial Hospital

Recruiting

Chemo Alone or in Combination With Radiation in Unresectable Cholangiocarcinoma

Cholangiocarcinoma

India
Bayer
Regeneron Pharmaceuticals

Completed

A Study to Learn More About How Well 8 Milligram Aflibercept Works and How Safe it is in Chinese Participants With Diabetic Macular Edema (PHOTONiC)

Diabetic Macular Edema

China, Hong Kong
Gustave Roussy, Cancer Campus, Grand Paris
National Cancer Institute, France

Active, not recruiting

Multicentric Comparative Study Between a Conventional and an Intensive Follow up Strategy After Treatment of a Head and Neck Squamous Cell Carcinoma (SURVEILL'ORL)

Head and Neck Squamous Cell Carcinoma

France
Merck Sharp & Dohme LLC

Completed

Pembrolizumab (MK-3475) Plus Gemcitabine/Cisplatin Versus Placebo Plus Gemcitabine/Cisplatin for First-Line Advanced and/or Unresectable Biliary Tract Carcinoma (BTC) (MK-3475-966/KEYNOTE-966) (KEYNOTE-966)

Biliary Tract Carcinoma

United States, Argentina, Australia, Belgium, Brazil, Canada, Chile, China, France, Germany, Hong Kong, Ireland, Israel, Italy, Japan, Malaysia, Netherlands, New Zealand, Spain, Taiwan, Thailand, United Kingdom, South Korea, Turkey (Türkiye)
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Active, not recruiting

Temozolomide With or Without Capecitabine in Treating Patients With Advanced Pancreatic Neuroendocrine Tumors

Gastrinoma | Glucagonoma | Insulinoma | Pancreatic Polypeptide Tumor | Recurrent Islet Cell Carcinoma | Somatostatinoma | Islet Cell Carcinoma

United States
Imvax

Active, not recruiting

A Phase 2b Clinical Study With a Combination Immunotherapy in Newly Diagnosed Patients With Glioblastoma

Glioblastoma

United States
LG Chem

Active, not recruiting

A Clinical Study in Healthy Adults to See How the Body Processes and How Safe a Tablet That Combines Gemigliptin, Dapagliflozin, and Metformin is, Compared With Taking Zemiglo and Xigduo XR Together While Fasting.

Healthy Volunteers | Fasting Conditions

South Korea
Brigham and Women's Hospital
Boston Scientific Corporation

Suspended

Augmented Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for PE (SONIC-PE)

Pulmonary Embolism | Right Ventricular Dysfunction | Right Ventricular Failure

United States
ViiV Healthcare

Active, not recruiting

A Study to Evaluate the Efficacy, Safety, and Tolerability of Using an Oral Once-daily 2 Drug Regimen Compared to an Oral Once-daily 3 Drug Regimen for the Treatment of Human Immunodeficiency Virus (HIV)-1 in Adults Who Have Not Previously Taken Antiretroviral Therapy (VOGUE)

HIV Infections | HIV

Spain, Poland, France, Israel, Belgium, Portugal, Germany, Greece, Japan, Ireland, Switzerland, United Kingdom, Denmark, Sweden, Italy, Argentina, Mexico
European Institute of Oncology
Istituto Oncologico Veneto IRCCS; Ente Ospedaliero Ospedali Galliera; Istituto...

Active, not recruiting

Low Dose TamOxifen and LifestylE Changes for bReast cANcer prevenTion (TOLERANT)

Ductal Carcinoma in Situ | RAD51C Gene Mutation | RAD51D Gene Mutation | PALB2 Gene Mutation | Lobular Carcinoma in Situ | ATM Gene Mutation | CDH1 Gene Mutation | CHEK2 Gene Mutation | BRCA Mutation

Italy
Joseph J. Cullen, MD, FACS
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

A Phase I Trial of High-Dose Ascorbate in Glioblastoma Multiforme

Glioblastoma | Glioblastoma Multiforme | GBM

United States
Ralph Hauke
Prometheus Laboratories; Nebraska Cancer Specialists; Midwest Cancer Center-Legacy

Terminated

Anti-PD-1 Antibody With HD IL-2 in Metastatic Melanoma

Melanoma

United States
Allodynic Therapeutics, Inc

Completed

The Preventive Treatment of Migraine With Low-Dose Naltrexone and Acetaminophen Combination

Migraine With or Without Aura

United States
Sumitomo Pharma America, Inc.

Terminated

A Phase 1b/2 Study of Alvocidib Plus Decitabine or Azacitidine in Patients With MDS

Myelodysplastic Syndromes (MDS)

United States
Novartis Pharmaceuticals

Completed

Lapatinib and Bevacizumab for Metastatic Breast Cancer

Neoplasms, Breast

United States
Aga Khan University

Completed

Isoflurane Versus Propofol for Removal of LMA in Children

Complication of Anesthesia

Pakistan
University of California, San Francisco
National Institute of Dental and Craniofacial Research (NIDCR)

Completed

Glass Ionomer Sealant and Fluoride Varnish Study to Prevent Early Childhood Caries (GIFVT)

Dental Caries

United States
Janssen Research & Development, LLC

Completed

Study of Subcutaneous and Intravenous Velcade in Combination With Dexamethasone in Chinese Subjects With Relapsed and Refractory Multiple Myeloma

Multiple Myeloma

China
Sanofi

Completed

Study of Capecitabine and Cyclophosphamide Administered as a Single Pill in Patients With Advanced Breast Cancer (METRO-ABC)

Breast Cancer Metastatic

India
Emory University
Ipsen

Completed

Dysport for the Treatment of OMD

Tardive Dystonia | Oral Dystonia

United States
National Institute of Diabetes and Digestive and...
University of Texas Southwestern Medical Center

Completed

Randomized Study of Acetylcysteine in Patients With Acute Liver Failure Not Caused by Acetaminophen

Acute Liver Failure

United States
Hadassah Medical Organization

Unknown

Nivolumab in Relapsed Pediatric Solid Tumors

Antibodies, Neoplasm
Indivior Inc.

Completed

Single Ascending Dose Study of RBP-7000

Schizophrenia

United States
Merck KGaA, Darmstadt, Germany

Completed

Phase 2b Randomized Controlled Study of Tecemotide (L-BLP25) for Immunotherapy of NSCLC (Non-Small Cell Lung Cancer)

Carcinoma, Non-Small-Cell Lung | Lung Neoplasms

Germany
Janssen Research & Development, LLC

Completed

Bioequivalence Study of Metformin Component of Canagliflozin and Metformin Fixed Dose Combination Immediate Release (IR) Tablet Comparing With Metformin IR Tablet Co-administered With Canagliflozin Tablet in Healthy Fed and Fasted Participants

Healthy

United States
National Cancer Institute (NCI)

Completed

Sorafenib and Bortezomib in Treating Patients With Advanced Cancer

Stage III Multiple Myeloma | Unspecified Adult Solid Tumor, Protocol Specific | Refractory Multiple Myeloma | Refractory Chronic Lymphocytic Leukemia | Stage IV Chronic Lymphocytic Leukemia

United States
Duke University
GlaxoSmithKline; Kilimanjaro Christian Medical Centre, Tanzania; Kibongoto National...

Completed

Tuberculosis and Human Immunodeficiency Virus (HIV) Immune Reconstitution Syndrome Trial (THIRST) (THIRST)

HIV | Tuberculosis

Tanzania
Michael Mauer, MD
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Merck... and other collaborators

Completed

Renin Angiotensin System Study (RASS/B-RASS)

Type 1 Diabetes

Canada
University of California, San Francisco
Stanford University; Federal University of São Paulo; Aravind Eye Care System

Active, not recruiting

Rose Bengal Electromagnetic Activation With Green Light for Infection Reduction II (REAGIR II)

Bacterial Keratitis

Brazil, India
Cancer Research Campaign Clinical Trials Centre

Unknown

Hyperthermia and Mitomycin C, Bacillus Calmette-Guerin, or Standard Therapy as Second-Line Therapy in Treating Patients With Recurrent Bladder Cancer

Bladder Cancer

United Kingdom
Tehran University of Medical Sciences

Completed

Two Schedules of Hepatitis B Vaccination in Predialysis Chronic Renal Failure Patients

Renal Failure
Hospital Universitario Ramon y Cajal

Terminated

Efficacy of Tocilizumab in Modifying the Inflammatory Parameters of Patients With COVID-19 (COVITOZ-01) (COVITOZ-01)

Covid19

Spain
University Hospital, Strasbourg, France

Unknown

Comparison of Two Laryngoscopes: Single-use Device Laryngobloc ® (SU) Versus Reusable Handle With Disposable Metal Blade (R) (MUUR)

Contamination of the Handles | Quality of the Laryngoscopy

France
Guangzhou Fermion Technology Co., LTD

Completed

A Phase 1 Study of FZ008-145 in Healthy Subjects.

Healthy

Australia
Kahramanmaras Sutcu Imam University

Completed

Effects of Chiropractic and Exercise on Wrist Proprioception and Grip Strength in Individuals With Mechanical Neck Pain

Neck Pain

Turkey
Laval University

Completed

Immunogenicity and Safety of Gardasil-9 and Cervarix

HPV Vaccines Immunogenicity and Safety

Canada
Second Affiliated Hospital of Guangzhou Medical...

Recruiting

Triple Hypoglycemic Regimens In Patients With Newly Diagnosed Type 2 Diabetes Mellitus (TRED)

Type 2 Diabetes

China
Saint John's Cancer Institute
Chordoma Foundation

Recruiting

Pembrolizumab and Pemetrexed for Progressive Chordoma

Chordoma | Chordomas

United States
Melanoma Institute Australia
Bristol-Myers Squibb

Recruiting

Neoadjuvant Nivolumab and Relatlimab in Merkel Cell Carcinoma

Merkel Cell Carcinoma

Australia
The Institute of Molecular and Translational Medicine...
Cancer Research Foundation CR

Recruiting

Study of Early Cancer Biomarkers in Breath Condensate in Population of Individuals With High-Risk of Lung Cancer Undergoing LDCT Screening.

Lung Cancer

Czechia
Fujian Cancer Hospital

Not yet recruiting

A Study to Evaluate Lenvatinib Plus Tislelizumab for Locally Advanced Unresectable or Metastatic Hepatocellular Carcinoma With Hepatitis B Virus Infection and Biomarker Analyses

Hepatocellular Carcinoma
Lawson Health Research Institute

Recruiting

Flexible vs. Fixed Diuretic Regimen in the Management of Chronic Heart Failure: A Pilot Study

Heart Diseases | Heart Failure

Canada
Radboud University Medical Center

Recruiting

Pharmacokinetic Boosting of Olaparib to Improve Exposure, Tolerance and Cost-effectiveness (PROACTIVE)

Cancer

Netherlands
National Taiwan University Hospital
Mackay Memorial Hospital; Kaohsiung Medical University; Tri-Service General Hospital and other collaborators

Recruiting

Radiotherapy Versus Low-Dose Tamoxifen Following Breast Conserving Surgery for Low-Risk Breast Ductal Carcinoma in Situ

Breast Ductal Carcinoma in Situ

Taiwan
Thammasat University

Completed

Intravenous Nalbuphine for Prevention of Intrathecal Morphine-induced Nausea and Vomiting in Patients Undergoing Cesarean Section: A Double-blind, Randomized Controlled Trial.

Caesarean Section | Postoperative Nausea and Vomiting | Intrathecal Morphine | Neuraxial Opioid

Thailand
AstraZeneca
Karolinska Institutet; CTC Clinical Trial Consultants AB

Terminated

AZD3427 Effects on Renal Perfusion in Heart Failure Patients With Reduced Ejection Fraction and Renal Impairment (Re-PERFUSE)

Renal Impairment | Heart Failure With Reduced Ejection Fraction (HFrEF)

Sweden
Hellenic Scientific Society for the Study of AIDS...
Gilead Sciences

Completed

Rapid Antiretroviral Treatment Initiation With BIC/FTC/TAF in HIV-infected People Who Inject Drugs (PWID) (BFTAFDU)

HIV Positive People Who Inject Drugs

Greece
Janssen Research & Development, LLC

Completed

A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin XR Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants

Healthy

United States

Search clinical trials for: Dose decrease

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