Search clinical trials for: Dose decrease

Total 7779 results

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Ipsen

Completed

Long Term Safety And Effectiveness Of Dysport® In Adults With Cervical Dystonia

Cervical Dystonia

United States
Brigham and Women's Hospital
Mclean Hospital

Terminated

MDMA-assisted Therapy in People With Anxiety Related to Advanced Stage Cancer

Cancer | Anxiety Disorder

United States
Jianxiang Wang

Unknown

Treatment of Elderly Chinese Acute Myeloid Leukemia Patients Aged 65 to 75 Years Old

Acute Myeloid Leukemia

China
Yonsei University

Completed

Safety and Efficacy of the Early Introduction of Everolimus (Certican®) With Low Dose of Cyclosporine in de Novo Kidney Recipients After 1 Month of Transplantation

Planned Kidney Transplantation

Korea, Republic of
FORUM Pharmaceuticals Inc
Syneos Health

Completed

Safety, Tolerability, and Pharmacokinetic Study of EVP-6124 in Patients With Alzheimer's Disease

Central Nervous System Diseases | Alzheimer's Disease

United States
Actavis Inc.

Completed

Single Dose Two-Way Crossover Fasted Bioequivalence Study of Nabumetone 750 mg Tablets in Healthy Volunteers

Healthy

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Terminated

Study Evaluating of Calcineurin Inhibitor and Sirolimus (Rapamune) Treatment in Liver Transplant Recipients

Liver Transplantation

Italy, Belgium, Spain, France, Canada, Germany, United States, United Kingdom, Portugal, Czech Republic, Switzerland, Netherlands
University Hospital, Clermont-Ferrand

Completed

Low-Dose Dobutamine Tc-99m-Mibi Gated SPECT to Predict Left Ventricular Remodelling in Patients Reperfused in the Acute Phase of MI

Myocardial Infarction | Ischemic Heart Disease

France
Chang Gung Memorial Hospital

Completed

Long-Term Lead Chelation Therapy and Progressive Renal Insufficiency

Urologic Disease

China
University of California, San Francisco
National Eye Institute (NEI); Stanford University; Federal University of São... and other collaborators

Completed

Rose Bengal Electromagnetic Activation With Green Light for Infection Reduction (REAGIR)

Fungal Keratitis | Acanthamoeba Keratitis

Brazil, India
Sequella, Inc.

Completed

Safety, Tolerability And Pharmacokinetics Study Of Single Doses Of PNU-100480 In Healthy Adults

Tuberculosis

United States
Centre Hospitalier Universitaire Vaudois

Completed

Characteristics of Popliteal Sciatic Nerve Block in Patients With and Without Diabetic Neuropathy

Diabetic Neuropathy

Switzerland
Perrault Louis P.
Montreal Heart Institute; Somahlution LLC

Completed

A Study to Evaluate the Use of SOMVC001 (GALA) Vascular Conduit Preservation Solution in Patients Undergoing CABG (STEPS) (GALA)

Coronary Artery Disease

Canada
Oregon Health and Science University
National Heart, Lung, and Blood Institute (NHLBI); National Institute of Environmental...

Completed

Evaluating the Effects of Supplemental Vitamin C on Infant Lung Function in Pregnant Smoking Women

Smoking | Pregnancy

United States
Peking University

Recruiting

The Effectiveness and Safety of FK-506 for the Treatment of Posner-Schlossman Syndrome

Posner Schlossman Syndrome

China
GWT-TUD GmbH

Completed

Prospective German Very High Cardiovascular Risk Patients Dyslipidemia Treatment Indication Registry (PERI-DYS)

Familial Hypercholesterolemia - Homozygous | Hypercholesterolemia, Familial | Familial Combined Hyperlipidemia | Dyslipoproteinemias

Germany
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy, Amifostine, and Peripheral Stem Cell Transplantation in Treating Patients With Stage II, Stage III, or Stage IV Breast Cancer

Breast Cancer

United States
Janssen-Cilag International NV

Completed

A Study in Healthy Participants to Evaluate the Effects of Multiple Doses of JNJ-55308942 on Cytochrome P450 Substrate Activity and on the Pharmacokinetics of Levonorgestrel/Ethinyl Estradiol

Healthy

Belgium
National Cancer Institute (NCI)

Terminated

Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097, Paclitaxel, and Carboplatin Before Surgery in Treating Patients With Stage II or Stage III Triple-Negative Breast Cancer

Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IIA Breast Cancer | Stage IIB Breast Cancer | Stage IIIC Breast Cancer | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast Carcinoma

United States
Region Skane
Swedish Lung Cancer Study Group

Recruiting

EGFR-mutated Lung Cancer in Randomized Investigator-Initiated Study (ERIS)

Non-Small Cell Lung Cancer

Sweden
Egymedicalpedia

Recruiting

Low Dose Aspirin for Prevention of Early Pregnancy Loss

Pre-Eclampsia

Egypt
Protherics Medicines Development Limited
Resonance Health

Recruiting

Retrospective Registry Study of Patients With Cancer Treated With High-dose Methotrexate

Acute Kidney Injury | Drug Toxicity

Spain, France, Italy
Shandong University

Not yet recruiting

14-day Double Therapy Versus Bismuth Quadruple Therapy in First-line Treatment of Helicobacter Pylori Infection

Helicobacter Pylori Infection

China
Women's Hospital School Of Medicine Zhejiang University

Recruiting

The Investigation of the Prediction Model and Prevention Strategy of Serious Pregnancy Complications in Hypertensive Disorders of Pregnancy Based on the Chinese Population (HDP-RPP)

Pregnancy Complications | Hypertensive Disorder of Pregnancy

China
RenJi Hospital

Recruiting

Preventive Effects of Aspirin as Adjuvant Therapy in Patients With Locally Advanced Renal Cell Carcinoma

Aspirin as Adjuvant Therapy in Patients With Surgically Treated High Risk Renal Cell Carcinoma

China
Memorial Sloan Kettering Cancer Center
Bristol-Myers Squibb

Active, not recruiting

Temozolomide, Cisplatin, and Nivolumab in People With Colorectal Cancer

Colorectal Adenocarcinoma

United States
Aarhus University Hospital

Enrolling by invitation

Effects of Total Thyroid Removal on Parathyroid Function and Quality of Life

Quality of Life | Hypoparathyroidism Post-surgical

Denmark
Women and Infants Hospital of Rhode Island

Withdrawn

Adherence to Universal Aspirin Compared to Screening Indicated Aspirin for Prevention of Preeclampsia

Medication Adherence | Preeclampsia

United States
Queen Mary University of London
AstraZeneca

Completed

A Randomized Study of AZD2014 in Combination With Fulvestrant in Metastatic or Advanced Breast Cancer (MANTA)

Estrogen Receptor Positive Breast Cancer

Spain, United Kingdom, France, Portugal, Georgia, Korea, Republic of, Germany, Hungary, Romania
Istanbul Training and Research Hospital

Completed

Effects of Subanesthetic Dose of Ketamine Given on Postoperative Mood in Patients Undergoing Fractional Curettage

Ketamine | Woman | Minor Surgical Procedure | Total Mood Score

Turkey
University of Maryland, Baltimore

Terminated

Pelvic Radiotherapy With Concurrent Neoadjuvant FOLFOX for Patients With Newly Diagnosed Rectal Adenocarcinoma (GCC 1314)

Rectal Adenocarcinoma

United States
Leonardo Clavijo
Amgen

Unknown

Effect of Evolocumab in Patients With Critical Limb Ischemia (Evol-CLI) (Evol-CLI)

Critical Limb Ischemia

United States
Bayer

Terminated

Study Testing Radium-223 Dichloride in Relapsed Multiple Myeloma

Multiple Myeloma

Korea, Republic of, Spain, United States
GlaxoSmithKline

Completed

Crossover Study Comparing Fluticasone Furoate (FF)/Vilanterol (VI) Once Daily Versus Fluticasone Propionate (FP) Twice Daily in Subjects With Asthma and Exercise-Induced Bronchoconstriction (EIB)

Asthma

United States, Canada
Cui Xulei

Completed

Quadratus Lumborum Block : Effect on Acute Pain and Quality of Recovery After Laparoscopic Renal Surgery

Pain Management | Laparoscopic Renal Surgery | Nerve Block

China
Boryung Pharmaceutical Co., Ltd

Completed

Drug Interaction Study of Fimasartan/Amlodipine/Hydrochlorothiazide in Healthy Male Subjects

Drug-Drug Interaction

Korea, Republic of
Mallinckrodt

Completed

Inhaled Nitric Oxide (INO) for the Prevention of Bronchopulmonary Dysplasia (BPD) in Preterm Infants

Bronchopulmonary Dysplasia

United States, Canada
AstraZeneca

Completed

A Study to Assess the Bioavailability and to Compare the Pharmacokinetics of AZD7594 Inhaled Via Monodose Inhaler and Multiple-dose Dry Powder Inhalers (DPI) or Pressurized Metered-dose Inhaler (pMDI) in Healthy Male Subjects

Asthma | Chronic Obstructive Pulmonary Disease (COPD)

United States
Nair, Vinay, D.O.
Bristol-Myers Squibb; Icahn School of Medicine at Mount Sinai

Unknown

Early Conversion From CNI to Belatacept in Renal Transplant Recipients With Delayed and Slow Graft Function

Kidney Transplant | Delayed Graft Function

United States
Kaohsiung Kai-Suan Psychiatric Hospital
Department of Health, Executive Yuan, R.O.C. (Taiwan)

Completed

Olanzapine vs. Low-dose Olanzapine Plus Trifluoperazine

Schizophrenia

Taiwan
H. Lundbeck A/S

Terminated

Sleep Laboratory Study of MK0928 in Adult Patients With Primary Insomnia (0928-041)(TERMINATED)

Primary Insomnia
Naveen Poonai

Completed

Oral Morphine Versus Ibuprofen

Upper Extremity Fractures | Analgesia Post Fracture

Canada
Central South University

Unknown

The Biomarker for Immunosuppressive Agents Metabolism in Chinese Renal Transplant Recipients

Kidney Transplantation

China
Boehringer Ingelheim

Completed

A Comparison of 18g of Tiotropium Inhalation Capsules Once Daily and Atrovent Metered Dose Inhaler (2 Puffs of 20g, 4 Times Daily) in a Double-Blind, Double-Dummy, Efficacy and Safety Study in Adults With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

China
University of Pennsylvania
Bill and Melinda Gates Foundation

Completed

Two-Dose Methotrexate for Ectopic Pregnancy

Ectopic Pregnancy

United States
David Marcinek
Stealth BioTherapeutics Inc.

Recruiting

Study of Healthy Aging and Physical Function With Elamipretide (SHAPE)

Aging, Healthy

United States
Ruijin Hospital

Recruiting

Study on the Safety and Tolerability of PD-1 Knockout Tumor-infiltrating T Cells (TILs) in the Treatment of Advanced Colorectal Cancer

Colorectal Cancer (CRC) | PD-1 | Tumor Infiltrating Lymphocytes

China
Medical University of Vienna

Not yet recruiting

Preoperative Use of Liraglutide Additionally to Common Dietological Measures as Opposed to Dietological Measures Alone

Obesity, Adolescent
Medical University of Warsaw

Recruiting

Aspirin Dose Comparison in Elderly PCI Patients: 30mg vs. 75mg in Acute Coronary Syndrome (LowASA-PCI)

Myocardial Infarction | Acute Coronary Syndrome

Poland
Keymed Biosciences Co.Ltd

Recruiting

Dose Escalation and Expansion Study of CM313 in Subjects With Relapsed or Refractory Multiple Myeloma and Lymphoma

Lymphoma | Multiple Myeloma

China

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