Search clinical trials for: Dose decrease

Total 7779 results

Novartis Vaccines

Completed

Dose-finding Study of Four Dosage Levels of an H7N9 Influenza Vaccine in Adults Between Ages of 18 Years and 65 Years

H7N9 Influenza

United States
Longbio Pharma

Completed

A Study of Single and Multiple Dose Administration of LP-001 in Healthy Subjects

Myelodysplastic Syndrome (MDS)

China
Zhongmou Therapeutics

Not yet recruiting

Prospective, Randomized, Sham-controlled, Dose-finding I/II Trial of Safety and Efficacy of Modified Optogenetic Gene Therapy (ZM-02 Injection) (PRISM)

Retinitis Pigmentosa (RP)
Latigo Biotherapeutics

Completed

This is a Study Evaluating the Efficacy and Safety of LTG-001 for Acute Pain After Surgical Removal of Impacted Third Molars

Acute Pain, Postoperative

United States
Theravance Biopharma

Terminated

TD-1473 Long-Term Safety (LTS) Ulcerative Colitis (UC) Study

Ulcerative Colitis (UC)

United States, Australia, Bulgaria, Canada, France, Georgia, Germany, Greece, Hungary, Israel, Italy, Japan, Korea, Republic of, Poland, Portugal, Romania, Serbia, Slovakia, South Africa, Spain, Taiwan, Ukraine
Precigen Actobio T1D, LLC
TFS Trial Form Support; Intrexon Actobiotics NV, d/b/a Precigen Actobio

Completed

A Study to Assess the Safety and Tolerability of Different Doses of AG019 Administered Alone or in Combination With Teplizumab in Participants With Recently Diagnosed Type 1 Diabetes Mellitus (T1D)

Diabetes Mellitus, Type 1

United States, Belgium
The University of Texas Health Science Center,...

Terminated

Dose Ranging Study of the Safety and Efficacy of Orally Administered Lyophilized Fecal Microbiota Product (PRIM-DJ2727) for the Treatment of Recurrent Clostridium Difficile Infection (CDI)

Recurrent C. Difficile Infection

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Completed

Treating High Risk Leukemia With CD40 Ligand & IL-2 Gene Modified Tumor Vaccine

Leukemia

United States
Boehringer Ingelheim

Completed

Efficacy and Safety of BIIL 284 BS in Adult Patients With Active Rheumatoid Arthritis

Arthritis, Rheumatoid
Whanin Pharmaceutical Company

Completed

Safety and Efficacy of WIN-901X in Asthma

Asthma

Korea, Republic of
University Hospital, Ghent

Completed

Sevoflurane-Remifentanil Interaction: Multiple Response Surfaces, Validation of Calibration Stimuli, Validation of the Intraoperative Isobole Concept and Investigating Remifentanil Induced Opioid Tolerance

Anesthesia

Belgium
Longbio Pharma

Completed

A Study of Single and Multiple Doses of LP-003 in Healthy Adult Participants

Chronic Spontaneous Urticaria

China
Rob Erskine
University of East Anglia

Completed

Acute Resistance Exercise and Hydrolyzed Collagen Supplementation

Diet | Nutrition | Food

United Kingdom
Per Pfeiffer

Completed

Chemotherapy for Patients With Cancer of the Stomach (DOS)

First-line Treatment for Patients With Non-resectable Gastric Cancer or Cancer of the Esophagus or

Denmark
BioTheraVision, Inc.

Recruiting

Evaluation of BTV100 in Subjects With Dry Eye Disease

Dry Eye

Taiwan, Australia
HighField Biopharmaceuticals Corporation

Recruiting

HF158K1 in Patients With HER-2 Expressing Advanced Solid Tumors

Solid Tumors, Adult

China, United States
China Academy of Chinese Medical Sciences

Recruiting

The Dose-Effect Relationship of Wenxin Granules in the Treatment of Atrial Premature Beats

Atrial Premature Complexes

China
Jiangsu Province Centers for Disease Control and...

Completed

Phase Ⅱ Clinical Trial of 24-valent Pneumococcal Polysaccharide Conjugate Vaccine

Streptococcus Pneumoniae Pneumonia

China
Dr. Falk Pharma GmbH

Completed

Trichuris Suis Ova (TSO) Suspension Versus Placebo in Active Crohn's Disease (TRUST-2)

Crohn´s Disease

Germany
Pfizer

Recruiting

A Study to Learn About Medicine Called Ritlecitinib in Children Aged Between 6 to 12 Years With Severe Alopecia Areata (B7981027)

Severe Alopecia Areata

Japan, United States, Spain, China, Canada, Italy, United Kingdom, Czechia, Poland, France
MedRegen LLC
Vanderbilt University Medical Center

Not yet recruiting

MRG-001 as an Immunoregulatory and Regenerative Therapy for ARDS Patients (SUMMIT)

Respiratory Tract Diseases | Respiratory Failure | Acute Respiratory Distress Syndrome | Respiratory Distress Syndrome | Cytokine Storm
Perrigo CSCI
Analyze & Realize

Recruiting

Effects of Arterin Cholesterol for Reduction of Lipid Levels

Blood Cholesterol Lowers | LDL-C

Germany
Azafaros A.G.

Completed

Phase 2 Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral AZ-3102 in Patients With GM2 Gangliosidosis or Niemann-Pick Type C Disease (RAINBOW)

Niemann-Pick Disease, Type C | GM2 Gangliosidosis

Brazil
Bausch & Lomb Incorporated

Active, not recruiting

Phase 2 Study of BL1107 Eye Drops vs. Timolol in Adults With Primary Open Angle Glaucoma or Ocular Hypertension

Glaucoma

United States
Kyoto Drug Discovery and Development Co., Ltd.

Completed

A Study of the Efficacy and Safety of KUS121 in Participants With Acute Non-Arteritic Central Retinal Artery Occlusion (CRAO) (GION)

Central Retinal Artery Occlusion

United States
McMaster University

Completed

Ketone Dose and Cerebral Blood Flow Study (kCBF)

Cognition | Cerebrovascular Function

Canada
Longbio Pharma

Completed

Efficacy and Safety of LP-003 in Moderate-to-severe Seasonal Allergic Rhinitis Adult

Seasonal Allergic Rhinitis

China
ACADIA Pharmaceuticals Inc.

Terminated

Evaluate the Efficacy and Safety of ACP-044 in Subjects With Pain Associated With Osteoarthritis of the Knee

Osteoarthritis Pain

United States
QurAlis Corporation
Centre for Human Drug Research, Netherlands

Completed

A 3-way Cross-over Study on the Effects of QRL-101 on Transcranial Magnetic Stimulation and Nerve Excitability in Healthy Participants

Healthy

Netherlands
Renibus Therapeutics, Inc.

Completed

Effect of RBT-1 on Preconditioning Response Biomarkers in Subjects Undergoing CABG and/or Cardiac Valve Surgery (START)

AKI

United States, Australia, Canada
ACADIA Pharmaceuticals Inc.

Completed

Evaluate the Efficacy and Safety of ACP-044 for the Treatment of Acute Postoperative Pain Following Bunionectomy

Acute Postoperative Pain | Bunionectomy

United States
Oryzon Genomics S.A.
Alzheimer's Drug Discovery Foundation

Completed

Testing the Safety and Preliminary Efficacy of the New Drug ORY-2001 in Mild to Moderate Alzheimer's Disease (ETHERAL-US)

Mild to Moderate Alzheimer's Disease

United States
Children's Hospital Medical Center, Cincinnati

Completed

An Initial Study of AZD7325 in Adults With Fragile X Syndrome

Fragile X Syndrome

United States
Thomas Jefferson University

Completed

Gluten Ingestion Biomarkers in Patients w Gluten Sensitivity and Healthy Controls Peptides in Patients With Non-celiac Gluten Sensitivity and Healthy Patients: A Placebo-controlled Study (NCGS)

Non Celiac Gluten Sensitivity

United States
AbbVie (prior sponsor, Abbott)

Completed

Efficacy and Safety Study for Cognitive Deficits in Adult Subjects With Schizophrenia

Cognitive Deficits in Schizophrenia

United States
The Hospital for Sick Children

Terminated

Impact of Emergency Department Probiotic Treatment of Diarrheal Illness on Daycare Attendance

Gastroenteritis

Canada
Dennis Charney

Completed

Intranasal Administration of Neuropeptide Y in Healthy Male Volunteers (NPY)

Anxiety Disorders | Mood Disorder

United States
Circassia Limited
Cetero Research, San Antonio; Adiga Life Sciences, Inc.

Completed

Cat-PAD Follow on Study

Cat Allergy | Rhinoconjunctivitis

Canada
Guangzhou Patronus Biotech Co., Ltd.
Yantai Patronus Biotech Co., Ltd.

Active, not recruiting

A Safety and Immunogenicity Trial of a Respiratory Syncytial Virus Vaccine, LYB005 in Healthy Adults

Respiratory Syncytial Virus (RSV) | RSV Infection

Australia
Gustave Roussy, Cancer Campus, Grand Paris
LinKinVax

Recruiting

Therapeutic Vaccine in Patients With Human Papillomavirus HPV-positive Oropharyngeal Cancer (HPVDCVax)

Head and Neck Carcinoma | Adult Disease

France
Enanta Pharmaceuticals, Inc
hVIVO Services Limited

Completed

A Phase 2a Study to Evaluate EDP-938 in the Virus Challenge Model

RSV Infection

United Kingdom
Zhejiang University

Not yet recruiting

Safety and Efficacy Clinical Study of Severe Hemophilia B Treatment With KL001

Hemophilia B Without Inhibitor
Acerus Pharmaceuticals Corporation

Completed

Efficacy and Safety of TBS-2 Testosterone Gel in Women With Acquired Female Orgasmic Disorder

Female Orgasmic Disorder

United States, Canada, Australia
Marker Therapeutics, Inc.
M.D. Anderson Cancer Center

Not yet recruiting

MT-601 Administered To Patients With Locally Advanced Unresectable or Metastatic Pancreatic Cancer (PANACEA)

Pancreatic Cancer Metastatic | Pancreas Cancer | Pancreatic Cancer (Unresectable)

United States
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Recruiting

Study of HS-10517 in Chinese Adult Participants

COVID-19

China
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Completed

Bioequivalence Study of Eltrombopag Olamine Tablets in Healthy Subjects in the Fed State

Thrombocytopenia

China
Centre Jean Perrin

Completed

Targeted Radionuclide Therapy for Metastatic Melanoma [131I] ICF01012 (MELRIV-1)

Melanoma

France
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Completed

Bioequivalence Test of Eltrombopag Olamine Tablets in Humans Under Fasting State

Thrombocytopenia

China
Biocad

Terminated

Clinical Study of the Safety and Immunogenicity of a Recombinant Viral Vector AAV5 (Adeno-Associated Virus Type 5 )-RBD (Receptor Binding Domain)-S Vaccine for the Prevention of Coronavirus Infection (COVID-19) (COVER)

COVID-19 | Coronavirus Infection

Russian Federation
Vanderbilt University
Vanderbilt University Medical Center

Completed

Putative Cognitive Enhancer VU319

Cognitive Impairment

United States

Search clinical trials for: Dose decrease

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