Search clinical trials for: Dose decrease

Total 7779 results

Texas Tech University
Texas Tech University Health Sciences Center

Completed

Effects of L-theanine and Caffeine on Attention and Attention-related Brain Activity of Children With Attention Deficit Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder

United States
GlaxoSmithKline

Completed

A 5-Period, Single Dose, Phase 1 Study in Healthy Elderly Subjects to Assess Relative Bioavailability and Food Effect of Two Oral Formulations of GSK1325756 (Free Base vs HBr Salt) and Food Effect on the HBr Formulation When Given With Omeprazole

Pulmonary Disease, Chronic Obstructive

United States
Boehringer Ingelheim

Completed

FLOMAX® Versus HYTRIN® in Patients With the Signs and Symptoms of Benign Prostatic Hyperplasia

Prostatic Hyperplasia
Organisation for Oncology and Translational Research

Unknown

Letrozole and CDK 4/6 Inhibitor for ER Positive, HER2 Negative Breast Cancer in Postmenopausal Women

ER Positive, HER2 Negative Breast Cancer

China
Northumbria University

Completed

Cognitive and Cerebral Blood Flow Effects of 2-week Caffeine Abstinence or Maintenance

Cognitive Function | Mood | Caffeine Withdrawal | Cerebral Haemodynamics

United Kingdom
University of Birmingham
Newcastle University

Recruiting

GLycaemic Outcomes With Whey Protein in ageING (GLOWING)

Type 2 Diabetes

United Kingdom
Cairo University

Not yet recruiting

Microneedling With Vitamin C Versus Injectable Vitamin C for Depigmentation in Gingival Melanin Hyperpigmentation

Gingival Pigmentation
Wrightington, Wigan and Leigh NHS Foundation Trust
TRB Chemedica

Recruiting

Comparing Injection Treatments for Tennis Elbow (CITTE)

Lateral Epicondylitis | Tennis Elbow | Elbows Tendonitis

United Kingdom
Aristotle University Of Thessaloniki

Completed

24-hour Intraocular Pressure (IOP) Control With the Bimatoprost/Timolol Fixed Combination (BTFC)

Glaucoma

Greece
Solvay Pharmaceuticals

Completed

Analgesic Effectiveness of Three Different Doses of a New Formulation of Lamaline in a Model of Painful Knee (Gonarthrosis)

Knee Osteoarthritis

France
St. Justine's Hospital

Not yet recruiting

Oral Viscous Budesonide in Anastomotic Stricture After Esophageal Atresia Repair (OVB in EA) (OVB in EA)

Esophageal Atresia | Anastomotic Stenosis
Universidad Central de Venezuela
The ENose Company, Zutphen, Netherlands; Foundation for Research in Mycobacteria...

Unknown

Diagnostic Trial to Validate the Use of the E-Nose in Pulmonary TB

Tuberculosis, Pulmonary | e-Nose

Venezuela
Ron Postuma
Canadian Institutes of Health Research (CIHR); University of Toronto

Completed

Caffeine for Excessive Daytime Somnolence in Parkinson's Disease

Parkinson's Disease | Excessive Daytime Somnolence

Canada
SANE-Society of Anesthesiology
Instituto de Cardiologia do Rio Grande do Sul; Fundação Universitária de Cardiologia...

Completed

Clinical Trial Comparing Heparin and Protamine Fixed and Titrated Doses in Cardiac Surgery With Cardiopulmonary Bypass

Cardiac Surgery | Cardiopulmonary Bypass | Anticoagulation

Brazil
Karolinska University Hospital
Muhimbili University of Health and Allied Sciences

Completed

Treatment of Uncomplicated Childhood Malaria in Tanzania by Artemether+Lumefantrine - Efficacy and Genotyping

Malaria

Tanzania
National Cancer Institute (NCI)
NRG Oncology

Active, not recruiting

Testing the Addition of Ipatasertib to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) for Stage III or IV Epithelial Ovarian Cancer

Ovarian Endometrioid Adenocarcinoma | Primary Peritoneal High Grade Serous Adenocarcinoma | Fallopian Tube Endometrioid Adenocarcinoma | Ovarian High Grade Serous Adenocarcinoma | Fallopian Tube High Grade Serous Adenocarcinoma | Primary Peritoneal Endometrioid Adenocarcinoma | Stage III Fallopian... and other conditions

United States
Obafemi Awolowo University Teaching Hospital
Obafemi Awolowo University; Open Philanthropy

Recruiting

ATORvastatin in Pulmonary TUBerculosis: a POPulation PharmacoKinetics -PharmacoDynamics Sub-study (ATORTUB popPK-PD) (ATORTUB-PKPD)

Pulmonary Tuberculosis (TB)

Nigeria
Vall d'Hebron Institute of Oncology
Banc de Sang i Teixits

Recruiting

Evaluation of a Pragmatic Approach to Adoptive Cell Therapy (ACT) Using an IL2 Analog (ANV419) vs High Dose IL2 After Tumor Infiltrating Lymphocytes (TIL) Therapy in Patients With Melanoma, NSCLC and Cervical Cancer (PragmaTIL) (PragmaTIL)

Melanoma | Cervical Cancer | Non Small Cell Lung Cancer

Spain
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Low Dose Aspirin for the Prevention of Postpartum Related Breast Cancer

Breast Carcinoma

United States
Swedish Orphan Biovitrum
PSI CRO

Active, not recruiting

A Phase 3 Study of Pacritinib in Patients With Primary Myelofibrosis, Post Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis (PACIFICA)

Primary Myelofibrosis | Post-polycythemia Vera Myelofibrosis | Post-essential Thrombocythemia Myelofibrosis

Spain, United States, Brazil, Canada, France, India, Italy, Japan, Poland, Hungary, Belarus, Czechia, Bulgaria, Romania, United Kingdom, Australia, Georgia, Bosnia and Herzegovina, Serbia, South Korea, Israel, Kazakhstan, Russia, Ukraine
AstraZeneca
Parexel

Completed

AZD9291 Versus Gefitinib or Erlotinib in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer (FLAURA)

Locally Advanced or Metastatic EGFR Sensitising Mutation Positive Non Small Cell Lung Cancer

Belgium, United States, Canada, Poland, Romania, Thailand, Vietnam, Switzerland, France, Italy, Brazil, China, Malaysia, Germany, Spain, Taiwan, United Kingdom, Japan, Australia, Hungary, Portugal, Israel, Philippines, Sweden, Ukraine, Bu... and more
Pfizer

Withdrawn

A Study on 2 Different Combination Tablets of Nirmatrelvir Plus Ritonavir to Compare Them With Marketed Paxlovid in Healthy Participants

Healthy Participants | Biological Availability
St. Jude Children's Research Hospital
Schering-Plough

Active, not recruiting

Phase II Study Incorporating Pegylated Interferon In the Treatment For Children With High-Risk Melanoma

Malignant Melanoma

United States
The George Institute
Royal Prince Alfred Hospital, Sydney, Australia; Victor Chang Cardiac Research... and other collaborators

Terminated

Polydiuretic Therapy for HFpEF, a Randomised Controlled Trial

Heart Failure With Preserved Ejection Fraction

Australia
PharmaEssentia Japan K.K.

Completed

A Study to Evaluate P1101 in Japanese PV Patients

Polycythemia Vera (PV)

Japan
University of Southern California
The Leona M. and Harry B. Helmsley Charitable Trust

Completed

Specialized Technology Education for Pumps & Pens in Underserved Populations With Diabetes (STEPP-UP)

Type1diabetes

United States
Institut Cancerologie de l'Ouest
Hospices Civils de Lyon; Centre Antoine Lacassagne

Terminated

Phase-1 Study of Folinic Acid to Modulate MGMT Gene in Glioblastoma (FOLAGLI)

Glioblastoma | Grade IV Astrocytoma

France
Apsen Farmaceutica S.A.

Terminated

Phase III Efficacy and Tolerability Trial of the Fixed Dose Combination of Etodolac 400 mg and Cyclobenzaprine 10 mg Versus Isolated Active Substances in Pain Control After Impacted Third Molar Extraction (FDCETCB-III)

Pain, Acute

Brazil
Laboratorios Silanes S.A. de C.V.

Completed

Comparative Bioavailability Study Between Etoricoxib and Tramadol, Administered Individually or in Combination

Healthy

Mexico
The Third Xiangya Hospital of Central South University

Completed

Saccharomyces Boulardii as Pretreatment Before Rescue Therapy of Helicobacter Pylori

Helicobacter Pylori Infection

China
GlaxoSmithKline

Completed

Phase 2a, AMP Challenge, Dose Escalation Study to Assess the Dose Response for Topical Efficacy and Systemic Activity in Asthmatic Subjects

Asthma

United Kingdom, Germany
Emory University

Completed

AiDing Diuresis wIth Tolvaptan (ADD-IT) (ADD-IT)

Congestive Heart Failure | Cardiomyopathy

United States
Weill Medical College of Cornell University
Genentech, Inc.; Biogen

Completed

Higher Dose of Rituxan Versus Standard Doses of Rituxan With Cyclophosphamide, Vincristine, and Prednisone in Subjects With Chronic ITP

Immune Thrombocytopenic Purpura

United States
Arkansas Children's Hospital Research Institute

Completed

Preservation of Pancreatic Beta Cell Function Through Insulin Pump Therapy (ktpump)

Diabetes Mellitus

United States
Pearl Therapeutics, Inc.

Completed

Glycopyrronium and Formoterol Fumarate (GFF) Metered Dose Inhaler (MDI) Dose Indicator Study in Adults With Moderate to Very Severe COPD

COPD

United States
Noven Therapeutics

Completed

Efficacy/Safety Study of Brisdelle™ (Formerly Known as Mesafem) in the Treatment of Vasomotor Symptoms (VMS) (N30-003)

Postmenopausal Symptoms

United States
National Taiwan University Hospital
National Science Council, Taiwan

Completed

Efficacy of High Dose Dual Therapy, Sequential Therapy and Triple Therapy in H. Pylori Eradication

Helicobacter Infection

Taiwan
Pfizer

Completed

Estimation Of Effect Of Rifampin On Pharmacokinetics Of Crizotinib In Healthy Volunteers

Healthy

United States
Hallym University Medical Center

Completed

Pharmacogenetic Study of Methylphenidate in Attention Deficit/Hyperactivity Disorder(ADHD) (NETADHD)

Pharmacogenetics | Attention Deficit Disorder With Hyperactivity | Methylphenidate

Korea, Republic of
Sankyo Pharma Gmbh

Completed

Olmesartan and an add-on Treatment in Patients With Mild to Moderate Hypertension (OLMETREAT)

Essential Hypertension

France, Austria, Switzerland, Belgium, Germany, Italy, Netherlands, United Kingdom, Portugal
Mansoura University

Completed

Letrozole or Combined Metformin Clomiphene Citrate (CC) for Women With CC Resistant Polycystic Ovary Syndrome

Polycystic Ovary Syndrome

Egypt
Karuna Therapeutics
Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Recruiting

A Study to Evaluate the Effects of KarXT on the Drug Levels of Midazolam, Fexofenadine, and Digoxin

Healthy Volunteers

United States
Laboratorios Silanes S.A. de C.V.

Recruiting

Efficacy and Safety in the Combination of Ibuprofen / Loratadine Versus Ibuprofen Versus Loratadine

Common Cold

Mexico
Institut de Recherches Internationales Servier

Recruiting

Ivosidenib Plus Durvalumab and Gemcitabine/Cisplatin as First-Line Therapy in Participants With Locally Advanced or Metastatic Cholangiocarcinoma With an IDH1 Mutation

Locally Advanced, Unresectable or Metastatic Cholangiocarcinoma With an IDH1 Mutation

United States, France, Spain, Germany, Japan, Australia, South Korea, Brazil, Canada
Northwell Health

Recruiting

Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM

Glioblastoma | Brain Cancer | Glioblastoma Multiforme | GBM | Glioma, Malignant | Glioblastoma, IDH-wildtype | Glioblastoma Multiforme, Adult

United States
Klinički Bolnički Centar Zagreb
University of Zagreb

Recruiting

Switching From the Preserved to the Preservative - Free Latanoprost - Timolol FC in Glaucoma Patients With OSD

Ocular Hypertension | Primary Open-angle Glaucoma

Croatia
Laboratorios Silanes S.A. de C.V.

Completed

Comparative Bioavailability Study Between Ticagrelor and ASA Administered Individually or in Combination.

Healthy

Mexico
Theodore S. Johnson
National Cancer Institute (NCI); Emory University; Augusta University

Active, not recruiting

Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG

Glioblastoma | Ependymoma | Medulloblastoma | Diffuse Intrinsic Pontine Glioma

United States
Vastra Gotaland Region

Completed

Changes of Motor Function Tests in Congenital Myopathy Subjects Treated With Oral Salbutamol as Compared to no Treatment (COMPIS)

Musculoskeletal Diseases | Neuromuscular Diseases | Centronuclear Myopathy | Nemaline Myopathy | Congenital Myopathy | Myosin Storage Myopathy

Sweden
Kilimanjaro Clinical Research Institute
European and Developing Countries Clinical Trials Partnership (EDCTP)

Completed

Evaluation of Pharmacokinetics and Safety Tolerability of Higher Doses of Rifampic (HighRif C)

Clinical Trial

Tanzania

Search clinical trials for: Dose decrease

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