Search clinical trials for: Dose decrease

Total 7779 results

Parameswaran Hari

Completed

Study of Bendamustine and IXAZOMIB (MLN9708) Plus Dexamethasone in Relapsed/Refractory Multiple Myeloma

Multiple Myeloma

United States
Craig Hospital
Allergan; The Craig H. Neilsen Foundation

Completed

Investigating Botulinum Toxin A to Treat Acute Neck/Upper Shoulder Pain Following a New Spinal Cord Injury.

Pain | Spinal Cord Injury

United States
Ottawa Hospital Research Institute

Completed

Comparing Tapering Low Dose Dexamethasone to Other Standard of Care Therapies for TAPS in Breast Cancer Patients (REaCT-TAPS)

Pain Syndrome | Early-stage Breast Cancer

Canada
University of Wisconsin, Madison
Sanofi; Genzyme, a Sanofi Company

Terminated

Study of Docetaxel With Doxercalciferol or Placebo for Advanced Prostate Cancer

Prostate Cancer

United States
GlaxoSmithKline

Completed

A Study to Evaluate the 24 Hour Spirometric Effect (FEV1) of Fluticasone Furoate/Vilanterol Inhalation Powder (100mcg Fluticasone Furoate (FF)/25mcg Vilanterol (VI)) Compared With Salmeterol/Fluticasone Propionate Inhalation Powder (50mcg Salmeterol/500mcg Fluticasone Propionate (FP))

Pulmonary Disease, Chronic Obstructive

France, Germany, Spain, Russian Federation, Belgium, Ukraine, Philippines, Italy, Poland
Noven Therapeutics

Completed

Eight-Week Efficacy & Safety Study of Brisdelle™ (Formerly Known as Mesafem) in the Treatment of Vasomotor Symptoms Associated With Menopause

Hot Flashes

United States
Novacea
Schering-Plough

Suspended

A Study of Gemcitabine ± Erlotinib and DN-101 Versus Gemcitabine ± Erlotinib and Placebo in Patients With Advanced Pancreatic Cancer

Pancreatic Cancer

United States
Albert Schweitzer Hospital

Completed

Treatment of Malaria With Quinine Plus Sulfadoxine-Pyrimethamine

Malaria

Gabon
Sohag University

Recruiting

A Study of Acute Kidney Injury in Children at Sohag University Hospital

Acute Kidney Injury

Egypt
Universidad de Guanajuato
Hospital Regional de Alta Especialidad del Bajio

Unknown

Effect of Low Dose Combination of Linagliptin + Metformin to Prevent Diabetes

Insulin Resistance | Prediabetic State

Mexico
University of Georgia
The Hershey Company

Completed

Effect of Phytochemicals From Theobroma Cacao on Mental Energy

Mental Fatigue

United States
Pfizer

Completed

Study Conducted in Subjects With Rheumatoid Arthritis Who Have Moderate to Severe Disease Activity Despite Methotrexate Therapy With or Without Other Non Biologic Disease Modifying Antirheumatic Drugs (DMARDs)for at Least 12 Weeks Prior to Screening

Rheumatoid Arthritis

Hungary, Qatar, Romania, Ukraine, China, Czech Republic, Malaysia, Thailand, Lebanon, South Africa, Philippines, Brazil, Colombia, Egypt, Jordan, Mexico, Russian Federation, Taiwan, United Arab Emirates
University of Edinburgh
NHS Lothian

Completed

Effects of Urocortins on Forearm Arterial Blood Flow in Healthy Volunteers (Protocol 3)

Heart Disease | Vascular Disease

United Kingdom
Sunnybrook Health Sciences Centre
Focused Ultrasound Foundation

Recruiting

Intravenous Immunoglobulin (IVIG) and Blood-Brain Barrier Disruption in Amyotrophic Lateral Sclerosis (ALS) (ALSFUS003)

Amyotrophic Lateral Sclerosis | ALS

Canada
Xiangya Hospital of Central South University

Not yet recruiting

Metoprolol in Patients With HFrEF and COPD

Heart Failure With Reduced Ejection Fraction (HFrEF) | COPD (Chronic Obstructive Pulmonary Disease)
Irish Research Radiation Oncology Group

Recruiting

Optimising Patient Experience in Head and Neck Radiotherapy (OPEN)

Head and Neck Cancer

Ireland
Khon Kaen University

Unknown

Effectiveness of Budesonide Nasal Instillation in a Vertex-to-floor Position

Chronic Frontal Rhinosinusitis | Vertex to Floor Position

Thailand
Jordan D. Miller, Ph.D.
National Center for Research Resources (NCRR); National Center for Advancing... and other collaborators

Completed

Safety of Ataciguat in Patients With Moderate Calcific Aortic Valve Stenosis

Aortic Valve Stenosis

United States
Ioannis Koutsourelakis

Completed

Effect of Nasal Steroids in Snoring Intensity

Snoring

Greece
University Medical Center Groningen

Completed

Drug Interaction Study Between Linezolid and Clarithromycin in Tuberculosis Patients

Multidrug-resistant Tuberculosis | Extensively Drug-resistant Tuberculosis

Netherlands
Medical University of Vienna

Completed

Effects of Vitamin C on Hyperoxia-Induced Reduction of Retinal Blood Flow

Ocular Physiology | Regional Blood Flow

Austria
Tomsk National Research Medical Center of the Russian...
Russian Science Foundation

Recruiting

Mechanical Dyssynchrony and Microvascular Dysfunction by SPECT (MD&MD)

Myocardial Blood Flow Reserve | Coronary Arterial Disease (CAD) | Mechanical Dyssynchrony

Russia
Zhejiang Cancer Hospital

Recruiting

Rituximab-Methotrexate-Temozolomide-Thiotepa (RMTT) Regimen As First-line Therapy for PCNS DLBCL

Primary Central Nervous System Lymphoma

China
Beijing Hospital of Traditional Chinese Medicine

Not yet recruiting

A Multicentre Randomized Controlled Clinical Study on the Chitosan Nanocrystalline Qinteng Huoxue Runji Ointment Therapy for Psoriasis With Blood Stasis Syndrome.

Plaque Psoriasis
Phramongkutklao College of Medicine and Hospital
Silpakorn University

Recruiting

Dose Optimization by Pharmacokinetic/Pharmacodynamic of Antibiotics to Improve Clinical Outcome of Carbapenem Resistant Klebsiella Pneumoniae Bloodstream Infections in Critically Ill Patients at Phramongkutklao Hospital

Carbapenem Resistant Klebsiella Pneumoniae

Thailand
Assiut University

Not yet recruiting

Impact Of Montelukast On Allergic Rhinitis And Its Inflammatory Makers

Allergic Rhinitis
Washington University School of Medicine
Pfizer

Active, not recruiting

Los Tres Paso: Neoadjuvant Palbociclib Monotherapy, Concurrent Chemoradiation Therapy, Adjuvant Palbociclib Monotherapy in Patients With p16INK4a Negative, HPV-Unrelated Head and Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma

United States
Gilead Sciences

Terminated

Study of Oral Weekly GS-1720 and GS-4182 Compared With Biktarvy in People With HIV-1 Who Have Not Been Treated (WONDERS2)

HIV-1-infection

Spain, United States, Germany, Canada, South Africa, Poland, Portugal, Romania, Puerto Rico
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Canadian Cancer Trials Group; European Organisation...

Active, not recruiting

Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy With Adjuvant PCV Chemotherapy in Patients With Anaplastic Glioma or Low Grade Glioma

Brain and Central Nervous System Tumors

United States, Canada, France, Austria, Netherlands, Belgium
H. Lee Moffitt Cancer Center and Research Institute
Novartis; Celgene Corporation

Completed

Ofatumumab, High Dose Methylprednisolone, Ofatumumab and Lenalidomide Consolidative Therapy for Untreated CLL/SLL

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States
Al-Azhar University

Completed

The Effect of Sitagliptin, Pioglitazone and Dapagliflozine on Myocardial Infarction in Diabetic Rats

Myocardial Infarction | Diabetic

Egypt
Myovant Sciences GmbH

Completed

Study of Relugolix With Estradiol and Norethindrone Acetate in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Uterine Fibroids | Uterine Leiomyoma

United States, Italy, Poland, Czechia, Hungary, South Africa, Brazil, Chile
University of Washington

Completed

Effect of Post-operative Ibuprofen After Surgery for Chronic Rhinosinusitis

Chronic Rhinosinusitis (Diagnosis)

United States
Laboratorios Silanes S.A. de C.V.

Completed

Non-interaction Study of Chlorthalidone and Losartan in Fixed Combination, in Healthy Subjects, Under Fasting Conditions

Healthy

Mexico
Bagcilar Training and Research Hospital

Completed

Palonosetron vs. Ondansetron for Postoperative Nausea and Vomiting in Bariatric Surgery

Pain, Postoperative | Nausea, Postoperative | Vomiting, Postoperative | Patient Reported Outcomes | Antiemetics

Turkey
Novartis

Completed

Efficacy and Safety of Valsartan and Amlodipine (± HCTZ) in Adults With Moderate, Inadequately Controlled Hypertension

Hypertension

Germany
Children's Hospital of Philadelphia
Gateway for Cancer Research

Completed

Preventing Nephrotoxicity and Ototoxicity From Osteosarcoma Therapy

Osteosarcoma | Nephrotoxicity | Ototoxicity

United States
Midas Pharma GmbH

Completed

Drug-drug-interaction Study of Candesartan, Amlodipine and Atorvastatin

Healthy Volunteers

Jordan
Corcept Therapeutics

Completed

First-in-human Study in Healthy Subjects

Healthy

United Kingdom
National Research Council, Spain

Completed

Olive Oil and Nampt on Postprandial Inflammation and Atherosclerosis in the Setting of Metabolic Syndrome (OLNAMS)

Metabolic Syndrome

Spain
Daiichi Sankyo, Inc.

Completed

Pharmacokinetics (PK) Drug Interaction Study of Milademetan and Itraconazole or Posaconazole in Healthy Participants

Pharmacokinetics

United States
Chongqing Medical University

Unknown

Comparison of Tandospirone, Amlodipine and Their Combination in Adults With Hypertension and Anxiety

Hypertension | Anxiety

China
Harvard University Faculty of Medicine
National Institute of Allergy and Infectious Diseases (NIAID); Sanofi; University... and other collaborators

Completed

Trial of High-Dose Rifampin in Patients With TB (HIRIF)

Tuberculosis

United States, Peru, United Kingdom
GlaxoSmithKline

Completed

Study to Evaluate the 24-Hour Pulmonary Function Profile of Fluticasone Furoate (FF) /GW642444 (Vilanterol) (VI) Inhalation Powder 100/25mcg Once Daily Compared With Fluticasone Propionate/Salmeterol Inhalation Powder 250/50mcg Twice Daily in Subjects With Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

Germany, Poland, Romania, United States, Czechia, Russian Federation
Janssen-Cilag International NV

Completed

Study to Evaluate Optimized Retreatment and Prolonged Therapy With Bortezomib (OPTIMRETREAT)

Multiple Myeloma

France, Poland, Belgium, Germany, Israel, Portugal, Turkey, Finland, Sweden, Netherlands, Norway
University of Liverpool
ViiV Healthcare; Makerere University

Completed

Dolutegravir Interactions With Artemisinin-based Combination Therapies (DolACT)

HIV | Malaria

Uganda
Assistance Publique Hopitaux De Marseille

Unknown

Efficacy of Lidocaine Versus Placebo in Palliative Care Patients With Opioid-refractory Cancer Pain With Neuropathic Component: a Multicenter, Prospective, Double-blind Randomized Placebo-controlled Study. (LIDOSP)

Cancer | Pain With Neuropathic Component

France
Ajou University School of Medicine

Unknown

Cilostazol-Simvastatin Drug Interaction Study

Dyslipidemias | Peripheral Artery Disease

Korea, Republic of
Janssen-Cilag International NV

Completed

Treatment With Velcade (Bortezomib) Plus Dexamethasone (VD) or VD Plus Cyclophosphamide or VD Plus Lenalidomide in Patients With Multiple Myeloma Stabilized After 4 Cycles of VD (SEQUENTIAL)

Multiple Myeloma

France, United Kingdom, Spain, Poland, Serbia, Turkey, Greece, Germany, Hungary, Lithuania
Janssen-Cilag International NV

Completed

A Study of Relapse Prevention and the Effectiveness of Long-acting Injectable Risperidone and Quetiapine Tablets in the Treatment of Patients With Schizophrenia or Schizoaffective Disorder

Psychotic Disorders | Schizophrenia

France, Poland, Germany, Spain, Slovenia, Bulgaria, Romania, Israel, Greece, Sweden, Turkey, Czech Republic, Hungary, Lithuania, Latvia, Portugal, Croatia, Slovakia, Austria, United Kingdom, Estonia, Ireland, Denmark, Saudi Arabia

Search clinical trials for: Dose decrease

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