Search clinical trials for: Dose decrease

Total 7787 results

Laval University

Completed

Immunogenicity of Gardasil and Twinrix and the Effect of a Dose of Gardasil or Cervarix Given 42 Months Later.

Human Papillomavirus

Canada
Boehringer Ingelheim

Completed

A Study With BIBF 1120 in Patients With Hormone Refractory Prostate Cancer

Prostatic Neoplasms
Bayer

Completed

A Trial to Compare Prophylaxis Therapy to On-demand Therapy With a New Full Length Recombinant FVIII in Patients With Severe Hemophilia A (Leopold II)

Hemophilia A

China, United States, Ukraine, Taiwan, Mexico, Thailand, Romania, Colombia, Turkey, Serbia, Russian Federation, South Africa, Japan, Indonesia, Argentina, Czech Republic, India, Slovakia
Enterome
Quotient Clinical

Completed

First-in-Human Single and Multiple Dose of EB8018

Healthy Volunteers

United Kingdom
Pulmocide Ltd

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Single and Repeat Doses of PC945

Aspergillosis

United Kingdom
Medtronic BRC

Unknown

LINQ for impEdance meAsuremeNt While Off From HF Medication Study (LEAN HF)

Heart Failure

United Kingdom
National Cancer Institute (NCI)

Completed

A Study of RO4929097 in Patients With Advanced Renal Cell Carcinoma That Have Failed Vascular Endothelial Growth Factor (VEGF)/Vascular Endothelial Growth Factor Receptor (VEGFR) Therapy

Clear Cell Renal Cell Carcinoma | Recurrent Renal Cell Carcinoma | Stage IV Renal Cell Cancer

Canada
Guangzhou Chia Tai Innovative Pharmaceutical Co...

Completed

Safety, Tolerability, and Pharmacokinetics of a Single or Multiple Ascending Doses of CPX101

Overweight and Obesity

China
Changchun BCHT Biotechnology Co.

Enrolling by invitation

A Phase I Study to Evaluate the Safety, Tolerability, and Immunogenicity of an mRNA Vaccine Against Herpes Simplex Virus Type 2 (HSV-2) Post-Vaccination

Genital Herpes

China
Otsuka Pharmaceutical Development & Commercialization...

Completed

Study of the Effectiveness of Three Different Doses of OPC-34712 in the Treatment of Adults With Acute Schizophrenia (VECTOR)

Acute Schizophrenia

Korea, Republic of, United States, Serbia, Ukraine, Romania, Poland, Canada, Latvia, Japan
Haisco Pharmaceutical Group Co., Ltd.

Not yet recruiting

A Clinical Trial Evaluating the Efficacy and Safety of HSK55718 in Patients for Postoperative Pain Treatment in Orthopedic Surgery

Pain After Surgery
Haisco Pharmaceutical Group Co., Ltd.

Recruiting

A Clinical Trial Evaluating the Efficacy and Safety of HSK55718 in Patients for Postoperative Pain Treatment in Abdominal Surgery

Pain After Surgery

China
Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.

Recruiting

Efficacy and Safety of HDM1005 Compared to Tirzepatide in Obese Adults Without Diabetes

Obesity

China
Sinovac Biotech Co., Ltd

Active, not recruiting

Inactivated Bivalent Enterovirus Vaccine (Vero Cell) Phase I/II Clinical Trial

Hand, Foot and Mouth Disease | Herpangina

China
Innovent Biologics (Suzhou) Co. Ltd.

Suspended

Evaluation of IBI302 Injection in nAMD or DME

Diabetic Macular Edema | Neovascular Age-related Macular Degeneration

China
Chinese University of Hong Kong

Not yet recruiting

Novel Chinese Medicine Formula for Diabetes

Type 2 Diabetes

Hong Kong
Celularity Incorporated

Terminated

Natural Killer Cell (CYNK-001) IV Infusion or IT Administration in Adults With Recurrent GBM (CYNK001GBM01)

Glioblastoma Multiforme | Molecular Mechanisms of Pharmacological Action | Giant Cell Glioblastoma | Astrocytoma, Grade IV | Physiological Effects of Drugs | Peripheral Nervous System Agents | Analgesics | Analgesics, Non-narcotic | Cyclophosphamide | Immunosuppressive Agents | Immunologic Factors | Antiviral... and other conditions

United States
Vanderbilt-Ingram Cancer Center

Completed

Standard vs High-Dose Trivalent Inactivated Flu Vaccine in Adult Hematopoetic Stem Cell Transplant (HSCT) Recipients

Adult Stem Cell Hematopoetic Transplant

United States
National Cancer Institute (NCI)

Completed

Phase II Trial of the Gamma-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors/Aggressive Fibromatosis

Desmoid Tumors | Aggressive Fibromatosis

United States
National Cancer Institute (NCI)

Completed

RO4929097 in Treating Patients With Recurrent and/or Metastatic Epithelial Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Stage IV Fallopian Tube Cancer | Stage IV Ovarian Cancer | Stage IV Primary Peritoneal Cancer

United States, Canada
Berthold Langguth, MD, Ph.D.

Recruiting

High-dose Accelerated Theta Burst Stimulation for the Treatment of Alcohol Addiction (TBA)

Alcohol Dependence

Germany
AstraZeneca

Active, not recruiting

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of AZD0780 in Participants With Dyslipidaemia

Dyslipidaemia

China, Hong Kong
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Shorter Course, Hypofractionated Pre-Surgery Radiation Therapy in Treating Patients With Localized, Resectable Soft Tissue Sarcoma of the Extremity of Superficial Trunk

Stage II Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Stage IIIA Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Stage IIIB Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Resectable... and other conditions

United States
University of Maryland, Baltimore
Medical Technology Enterprise Consortium (MTEC)

Completed

Dengue 4 Human Infection Model (Dengue CVD 11000; DHIM-4)

Dengue

United States
Reade Rheumatology Research Institute
ZonMw: The Netherlands Organisation for Health Research and Development; Sint...

Completed

Adalimumab Dose Reduction Aiming Low Serum Concentration With Control of Disease Activity (ADDORA-low)

Rheumatoid Arthritis

Netherlands
Fundación de investigación HM
Syntax for Science, S.L

Terminated

Clinical Trial on the Efficacy and Safety of Bemiparin in Patients Hospitalized Because of COVID-19

Covid-19

Spain
Oregon Health and Science University

Terminated

Below Knee DVT Study

Deep Vein Thrombosis (DVT) | Blood Clots

United States
Boehringer Ingelheim

Completed

BI 207127 / Faldaprevir Combination Therapy in Hepatic Impairment (Child-Pugh B) Patients With Genotype 1b Chronic Hepatitis C Infection: HCVerso3

Hepatitis C, Chronic

United States, Germany, Spain, United Kingdom
Penn State University

Withdrawn

C1-INH Compared to Placebo at the Time of Prodromal Symptoms for Hereditary Angioedema (HAE) Exacerbation

Hereditary Angioedema
Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.

Recruiting

Clinical Trials of Quadrivalent Influenza Vaccine

Influenza, Human

China
Jiangsu Simcere Pharmaceutical Co., Ltd.

Completed

To Evaluate SSD8432/ Ritonavir in Adults With COVID-19

COVID-19 Patients

China
Societa Italiana di Endoscopia Digestiva
IRCCS Azienda Ospedaliero-Universitaria di Bologna; Federico II University; Azienda... and other collaborators

Completed

Evaluation of Two Different Regimens of Colon Preparations for Advanced Cleaning. (ERACLES)

Colonoscopy

Italy
Sanofi Pasteur, a Sanofi Company

Completed

Study of Different Formulations of a Clostridium Difficile Toxoid Vaccine Given at Three Different Schedules in Adults

Diarrhea | Clostridium Difficile Infection

United States
Hospital for Special Surgery, New York

Completed

Effect of Local Anesthetic Dose on Interscalene Block (Low Dose ISB)

Interscalene Block | Shoulder Arthroscopy

United States
Bial - Portela C S.A.

Completed

Tolerability, Safety and Pharmacokinetics of Four Single-doses of BIA 6-512 (Trans-resveratrol) and Their Effect on the Levodopa Pharmacokinetics

Parkinson Disease

Portugal
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy Study of Epinastine Nasal Spray in Subjects With Seasonal Allergic Rhinitis (P08648)

Seasonal Allergic Rhinitis
University of California, Los Angeles
Indivior Inc.

Unknown

Analgesic Response to Opioid Analgesics in Buprenorphine-Maintained Individuals

Analgesic Response

United States
Kure Cells, INC
CellServe LLC; Roya Clinical

Not yet recruiting

Study to Evaluate the Safety of UF-KURE-BCMA CAR T-Cells in Advanced Myeloma

Multiple Myeloma in Relapse | Multiple Myeloma, Refractory
Chengdu Zenitar Biomedical Technology Co., Ltd

Recruiting

Phase IIa Study on Flonoltinib Maleate Tablets in the Treatment of Patients With Polycythemia Vera

Polycythemia Vera (PV)

China
Wang Min
Lanyue Biotech (Hangzhou) Co., Ltd.

Recruiting

A Clinical Study Evaluating the Safety, Tolerability and Initial Efficacy of SKG0106 Intravitreal Injection in Diabetic Macular Edema (DME) Patients

Diabetic Macular Edema

China
Memorial Sloan Kettering Cancer Center
Vanderbilt University

Active, not recruiting

Study of the Effects of Pre-surgical Aerobic Exercise on Patients With Solid Tumors

Solid Tumors | Preoperative Aerobic Training

United States
National Taiwan University Hospital

Enrolling by invitation

Robotic Therapy Hybridized With Mirror Therapy in Stroke Rehabilitation

Stroke

Taiwan
AGC Biologics S.p.A.

Completed

A Modified Phase I Study of NGR-hTNF in Advanced Solid Tumors

Advanced Solid Tumors

Italy
Centre Chirurgical Marie Lannelongue

Active, not recruiting

Epidemiological Study to Assess the Prevalence of Lung Cancer (PREVALUNG)

Lung Cancer | Tobacco | Atherosclerotic Cardiovascular Event

France
Hvidovre University Hospital
Aalborg University Hospital; Region Örebro County; Danmarks Lungeforening

Completed

Automated Oxygen Titration During Walking in Patients With COPD

Chronic Obstructive Pulmonary Disease | Respiratory Failure

Denmark
LG Chem

Completed

An Ascending Dose, Single/Multiple Dosing, Food Effect Clinical Trial to Evaluate Pharmacokinetics, Safety and Tolerability in Healthy Subjects After Oral Administration of Gemigliptin (Phase I)

Type 2 Diabetes Mellitus

China
Grupo de Investigación Clínica en Oncología Radioterapia

Unknown

Dose-escalation Trial of Preoperative Radiotherapy and Concurrent Chemotherapy in Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

Spain
Jhpiego
Bill and Melinda Gates Foundation

Completed

Accelerating Newborn Survival in Ghana Through a Low-dose, High-frequency Health Worker Training Approach

Stillbirth | Neonatal Death
National Cancer Institute (NCI)

Terminated

Bortezomib in Treating Patients With Unresectable Locally Advanced or Metastatic Adenocarcinoma of the Bile Duct or Gallbladder

Gastrointestinal Cancer | Advanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Recurrent Extrahepatic Bile Duct Cancer | Recurrent Gallbladder Cancer | Unresectable Extrahepatic Bile Duct Cancer | Unresectable Gallbladder... and other conditions

United States
Amgen

Withdrawn

Study to Evaluate Darbepoetin Alfa in Pediatric Subjects With Anemia Due to Chronic Kidney Disease

Anemia | Chronic Kidney Disease

Search clinical trials for: Dose decrease

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