Search clinical trials for: Dose decrease

Total 7787 results

Carmel Medical Center
Technion, Israel Institute of Technology

Completed

Nanotechnology for Detection of Multiple Sclerosis Compared to Autoimmune and Neurological Diseases by Exhaled Samples

Multiple Sclerosis

Israel
Carmel Medical Center
Technion, Israel Institute of Technology

Completed

Applications of Nanotechnology in Multiple Sclerosis by Respiratory Samples (MS-NANOSE)

Multiple Sclerosis

Israel
Second Affiliated Hospital, School of Medicine,...

Recruiting

Efficacy of Individualized Rituximab in Maintaining Remission of Moderate and Severe Systemic Lupus Erythematosus

Autoimmune Diseases

China
Innovent Biologics (Suzhou) Co. Ltd.

Completed

A Study of IBI302 in Patients With nAMD

Neovascular Age-related Macular Degeneration

China
Boehringer Ingelheim

Completed

A Study to Test Whether Different Doses of Alteplase Help People With Severe Breathing Problems Because of COVID-19 (TRISTARDS)

Acute Respiratory Distress Syndrome

Spain, Germany, Italy, Belgium, Mexico, Netherlands, India, France, Malaysia, Austria, Brazil, Russian Federation, Turkey
University of Iowa

Completed

Covid-19 Associated Coagulopathy

COVID 19 Associated Coagulopathy

United States
Oramed, Ltd.
Integrium

Completed

Safety, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Multiple Oral Bedtime Doses of ORMD-0801 in Adult Patients With Type 2 Diabetes Mellitus (T2DM)

Diabetes Mellitus Type 2

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of Metformin HCl 500 mg ER Tablets Under Fasting Conditions

Healthy

United States
Massachusetts General Hospital

Not yet recruiting

Role of n On-contrast Chest CT (NCCT) Based CT V: Q in Patients With Acute Pulmonary Embolism (aPE)

Pulmonary Embolism Acute | Pulmonary Embolism (Diagnosis)

United States
Medical University of Warsaw

Not yet recruiting

Sustained Unresponsiveness (SU) to Sesame Protein Following Low-dose Oral Allergen-specific Immunotherapy

Food Allergy in Children

Poland
First Affiliated Hospital of Zhejiang University

Not yet recruiting

Inaticabtagene Autoleucel (Inati-cel; CNCT19) Treatment for Newly Diagnosed B-cell ALL Patients in CR1 (JUVENTAS-ALL05)

Acute Lymphoblastic Leukemia | B Cell ALL
Beam Therapeutics Inc.

Recruiting

A Phase 1/2, Dose-Exploration Study to Evaluate the Safety and Efficacy of BEAM-301 in Patients With Glycogen Storage Disease Type Ia (GSDIa)

Glycogen Storage Disease Type Ia

United States
Shanxi Medical University

Not yet recruiting

The Immunogenicity and Persistence of Booster Dose With Hepatitis B Vaccine in College Students

Hepatitis B Vaccine
Viriom

Not yet recruiting

Study Evaluating the Efficacy and Safety of AV5080 in Patients With Uncomplicated Influenza

Influenza

Russian Federation
Shanghai Chest Hospital

Recruiting

China Lung Cancer Screening (CLUS) Study Version 2.0

Lung Neoplasms

China
Memorial Sloan Kettering Cancer Center

Completed

Proton Re-Irradiation for Recurrent Head and Neck Cancer

Head and Neck Cancer

United States
Enterome
Covance

Completed

First-in-Human, Phase 1b/2a Trial of a Multipeptide Therapeutic Vaccine in Patients With Progressive Glioblastoma (ROSALIE)

Glioblastoma, Adult

United States, Spain, France, Germany
Geisinger Clinic
Novo Nordisk A/S

Terminated

Treatment of GLP-1 for Diabetic Bariatric Patients (NOVO-GLP1)

Diabetes Mellitus, Type 2

United States
Contrad Swiss SA

Completed

Evaluation of the Effect of the AI500™ SINGLE-DOSE GEL Medical Device in Patients With Reduced Knee Function

Knee Osteoarthritis | Knee Injuries | Pain, Acute | Knee Arthritis | Pain, Chronic | Knee Pain Swelling

Italy
Hipra Scientific, S.L.U

Completed

A Phase III Trial to Assess the Safety and Immunogenicity of a HIPRA's Candidate Booster Vaccination Against COVID-19.

COVID-19 | SARS-CoV-2 Acute Respiratory Disease

Spain, Italy
University Hospital, Ghent

Completed

Comparison of Adaptive Dose Painting by Numbers With Standard Radiotherapy for Head and Neck Cancer. (C-ART-2)

Primary Non-operated Squamous Cell Carcinoma of Oral Cavity | Primary Non-operated Squamous Cell Carcinoma of Oropharynx | Primary Non-operated Squamous Cell Carcinoma of Hypopharynx | Primary Non-operated Squamous Cell Carcinoma of Larynx

Belgium
University of Aarhus
Odense University Hospital; Aarhus University Hospital Skejby; Rigshospitalet...

Terminated

Dose Escalated Adaptive RadioTherapy in Definitive Chemo-radiotherapy for Esophageal Cancer (DART)

Esophageal Cancer

Denmark
Instituto Mexicano del Seguro Social

Completed

Anti-inflammatory Effect of Low-Dose Whole-Lung Radiation for COVID-19 Pneumonia

COVID-19 Pneumonia

Mexico
Shahid Beheshti University of Medical Sciences

Unknown

Low Dose Radiotherapy in COVID-19 Pneumonia

COVID | SARS (Severe Acute Respiratory Syndrome)

Iran, Islamic Republic of
Rigshospitalet, Denmark
Public Health Laboratory Ivo de Carneri

Unknown

NEO-study, Newborn Emergency Outcome (NEO)

Neonatal Death
AstraZeneca
Quotient Sciences

Completed

Mass Balance Recovery, Pharmacokinetics and Metabolite Profile and Identification of [14C]AZD7594

Asthma

United Kingdom
Mbarara University of Science and Technology
The Hospital for Sick Children

Unknown

Development of a Mobile Application for HBB Prompt Study (HBB-Prompt)

Neonatal Death | Birth Asphyxia

Uganda
University of Pittsburgh
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Completed

Low-Dose Radiation to Prevent Complications of Back Surgery

Failed Back Surgery Syndrome | Postlaminectomy Syndrome | Postdiscectomy Epidural Fibrosis

United States
Ankara University

Unknown

VKORC1 and CYP2C9 Gene Polymorphisms and Warfarin Management

Atrial Fibrillation | Peripheral Vascular Disease | Deep Vein Thrombosis | Pulmonary Embolism | Cardiac Thrombus | Heart Valve Replacement (Mechanical or Biological With AF) | Cardiomyopathy (Ischemic or Dilated)

Turkey
Ottawa Hospital Research Institute

Completed

High Dose Ace Inhibitor Therapy Versus Combination of ACE and ARB Therapy

Diabetic Kidney Disease

Canada
Sanofi Pasteur, a Sanofi Company

Completed

Safety and Immunogenicity of Quadrivalent Influenza mRNA Vaccine MRT5413 in Adult Participants18 Years of Age and Older

Influenza Immunization

Australia, United States, Puerto Rico
University of Oxford

Unknown

A Study of a Candidate COVID-19 Vaccine (COV003)

Coronavirus

Brazil
Hiroshima University
SBI ALApromo Co., Ltd., Japan

Completed

Effects of 5-Aminolevulinic Acid on Iron Deficiency Anemia

Iron Deficiency Anemia

Japan
Pfizer

Completed

A Study for Multiple Tablet Forms of The Study Medicine (PF-07220060) in Healthy Adults

Healthy Participants

United States
Merck Sharp & Dohme LLC

Completed

A Study of Safety, Tolerability, and Immunogenicity of the MRKAd5 Gag/Pol/Nef Vaccine in Healthy Adults (V520-016)

HIV Infections | HIV-1
University Medicine Greifswald

Completed

Pharmacokinetic and Pharmacodynamic Interactions Between the Cholesterol-lowering Ezetimibe and the Non-nucleoside Reverse Transcriptase Inhibitor Efavirenz During Chronic Treatment in Healthy Volunteers With Reference to Intestinal Expression of CYP3A4, UGT1A1, ABCB1 and ABCC2

Pharmacokinetics | Pharmacodynamics | Drug Interactions | Intestinal Transporter Expression

Germany
Memorial Sloan Kettering Cancer Center
Bristol-Myers Squibb; UConn Health; Adaptive Biotechnologies; MedGenome

Completed

Relationship Between Tumor Mutation Burden and Predicted Neo-antigen Burden in Patients With Advanced Melanoma or Bladder Cancer Treated With Nivolumab or Nivolumab Plus Ipilimumab (CA209-260)

Melanoma | Bladder Cancer

United States
Megalabs

Not yet recruiting

Biosimilarity Study of Intravenous Recombinant Human Erythropoietin in Healthy Volunteers (RUBI)

Healthy

India
Wugen, Inc.

Active, not recruiting

A Phase 1b Study of WU-NK-101 in Combination With Cetuximab

Squamous Cell Carcinoma of Head and Neck | Colorectal Cancer Metastatic

United States
Mitotech, SA
ORA, Inc.

Completed

Study of SkQ1 as Treatment for Dry-eye Syndrome (VISTA-1)

Dry Eye Syndrome

United States
CR-CSSS Champlain-Charles-Le Moyne

Completed

Vancomycin Dose Adjustments Comparing Trough Levels to The AUC/MIC Method Using a Bayesian Approach in a Hospitalized Adult Population (VancoDATABayes)

Adult | Vancomycin | Area Under Curve

Canada
Damascus Hospital

Withdrawn

Comparison of Low Against High Regimen of Proton Pump Inhibitors for Treatment of Acute Peptic Ulcer Bleeding

Peptic Ulcer Hemorrhage | Marginal Ulcer | Gastroduodenal Ulcer

Syrian Arab Republic
Actavis Inc.

Completed

A Relative Bioavailability Study of Metformin HCl 500 mg ER Tablets Under Fasting Conditions

Healthy

United States
Dana-Farber Cancer Institute
Bristol-Myers Squibb

Completed

Nivolumab Plus Ipilimumab in Thyroid Cancer

Thyroid Cancer

United States
Bristol-Myers Squibb

Active, not recruiting

Long-term Outcomes Among Patients With Programmed Death-ligand 1 <1% Metastatic Non-small Cell Lung Cancer Treated With First-line Nivolumab + Ipilimumab + 2 Cycles of Chemotherapy

Metastatic Non-small Cell Lung Cancer

United States
Novartis Pharmaceuticals

Terminated

A Proof of Concept and Dose-finding Study of XXB750 in Patients With Heart Failure

Heart Failure

Spain, Bulgaria, Germany, Italy, United States, Taiwan, China, India, Japan, Portugal, Hungary, Slovakia
Peter MacCallum Cancer Centre, Australia

Completed

Avelumab With Chemoradiation in Locally Advanced Rectal Cancer

Rectal Cancer

Australia
Novartis Vaccines

Completed

Persistence of Antibody Levels and Response to Fifth or Third Meningococcal B Recombinant Vaccine in 4-year Old Healthy Children Who Previously Participated in Study V72P12E1

Meningococcal Disease | Meningococcal Meningitis

Spain, Italy, United Kingdom, Czech Republic
Cairo University

Unknown

Soft Tissue Augmentation Around Immediate Implants In The Esthetic Zone

Recession, Gingival
Shanghai Huilun Pharmaceutical Co., Ltd.

Not yet recruiting

A Clinical Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Inhaled H057 in the Treatment of Acute Exacerbations of Bronchiectasis

Acute Exacerbations of Bronchiectasis

China

Search clinical trials for: Dose decrease

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