Search clinical trials for: Dose decrease

Total 7787 results

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Boehringer Ingelheim

Terminated

Single Rising Dose Study of BI 201335 ZW in Healthy Male Subjects

Healthy
University of Virginia

Completed

Trial for the Evaluation of the Effect of Systemic Low-dose Interleukin-2 (IL-2) on the Immunogenicity of a Vaccine Comprising Synthetic Melanoma Peptides Administered With Granulocyte-macrophage Colony-stimulating Factor (GM-CSF)-In-Adjuvant, in Patients With High Risk Melanoma (MEL36)

Melanoma
Medical University of Vienna
Polymun Scientific, Vienna, Austria

Completed

Recombinant Human Superoxide Dismutase (rhSOD) and Vascular Reactivity

Inflammation

Austria
State University of New York at Buffalo
National Institute on Minority Health and Health Disparities (NIMHD)

Recruiting

Project ASTHMA - Aligning With Schools To Help Manage Asthma and Improve Outcomes

Asthma in Children | Directly Observed Therapy

United States
Omar Mahmoud

Recruiting

Dose Adjusted Chemoradiotherapy in HPV-Associated Oropharynx Cancer of the Elderly ((DACHOC-E))

Frailty | Oropharynx Cancer

United States
Centre Francois Baclesse

Recruiting

Phase II Study of Intensity Modulated Radiotherapy in Dose Painting for Sinus Carcinomas After Endoscopic Surgery (SinocaRT)

Tumor, Solid

France
University of Nebraska

Recruiting

High-dose Brachytherapy Boost With Stereostatic Body Radiation Therapy to Intermediate or Higher Risk Prostate Cancer

Prostatic Cancer

United States
Institute of Hematology & Blood Diseases Hospital...

Recruiting

A Study of FVIII Gene Therapy for Hemophilia A

Hemophilia A

China
Shanghai General Hospital, Shanghai Jiao Tong University...

Recruiting

High Dose PET/CT-guided Intensity Modulated Radiotherapy and Concurrent Chemotherapy in Esophageal Cancer

Esophageal Cancer

China
Arnatar Therapeutics, Inc.

Completed

A Phase I Clinical Study of ART101 Injection in Healthy Adult Subjects

Hypertension (HTN)

China
Zhang Tao
Akeso Pharmaceuticals, Inc.

Active, not recruiting

SBRT-LDRT-Cadonilimab for Advanced Gastric, Colorectal and Ovarian Cancers With Peritoneal Metastases

Advanced Colorectal Cancer | Advanced Ovarian Cancer | Advanced Gastric Cancer | Peritoneal Metastasis

China
Norgine

Completed

A Monocentric Study to Investigate a New Low Dose Oral Gut Cleansing Solution

Colorectal Cancer

Germany
Sanofi Pasteur, a Sanofi Company

Completed

Immunogenicity and Safety of a Tetravalent Dengue Vaccine Booster Injection in Subjects Who Previously Completed a 3-dose Schedule

Dengue Fever | Dengue Hemorrhagic Fever

Singapore
S.M.Chang, MD
The Methodist Hospital Research Institute

Completed

Reducing Radioisotope Dose: the Half-Dose CZT Study

Coronary Artery Disease

United States
The Netherlands Cancer Institute

Completed

PET Response During Chemoradiation of Lung Cancer

NSCLC

Netherlands
Gruppo Italiano Malattie EMatologiche dell'Adulto

Completed

Short Course of Bortezomib in Anemic Patients With Refractory Cold Agglutinin Disease (CAD0111)

Refractory Cold Agglutinin Disease

Italy
GlaxoSmithKline

Completed

Alcohol Interaction Study

Alcoholism

Netherlands
Odense University Hospital

Completed

Breast Cancer Recurrence - the Accuracy of Dual-time PET/CT (BREAC-AUT)

Breast Cancer Recurrent

Denmark
Stanford University

Completed

Transplantation for Patients With Chronic Lymphocytic Leukemia

Leukemia, Lymphocytic, Chronic

United States
Rennes University Hospital

Not yet recruiting

Randomized Controlled Trial Testing the Efficacy of Transcranial Magnetic Stimulation by Accelerated & High-dose Theta-burst, Functional Imaging Guided, in the Treatment of Depression in Elderly Subjects With Cognitive Impairment (OLDEP-TBS)

Treatment Resistant Depression | Elderly Depression (≥65y.o.)
Hunan Cancer Hospital

Recruiting

LDRT and Chemoimmunotherapy in NPC With Liver Metastasis (Light)

Nasopharyngeal Cancinoma (NPC)

China
Shanghai Xinzhi BioMed Co., Ltd.
Shanghai Mianyi Biopharmaceutical Co., Ltd.

Recruiting

Evaluation of the Safety and Efficacy of Hemophilia A Gene Therapy Drugs

Hemophilia A

China
Matthew J. Frigault, M.D.
Novartis

Completed

Tisagenlecleucel In Primary CNS Lymphoma

Primary CNS Lymphoma | Refractory Primary CNS Lymphoma | Relapsed Primary CNS Lymphoma

United States
CinDome Pharma, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of CIN-102 (Deudomperidone) in Adults With Diabetic Gastroparesis

Diabetic Gastroparesis

United States
University Hospital, Ghent
University Ghent

Active, not recruiting

Observational Prospective Study on Resective and Regenerative Periodontal Therapy: Short & Longterm Follow-up (UZFLAPSTUD)

Periodontitis | Periodontal Diseases

Belgium
Beijing Tongren Hospital

Completed

Optimization of Intestinal Preparation in Older Patients

Colonoscopy | Older Adults

China
Institut du Cancer de Montpellier - Val d'Aurelle

Completed

Sphincter-preserving Surgery After Preoperative Treatment of Ultra-low Rectal Carcinoma (GRECCAR1)

Rectal Cancer

France
Qpex Biopharma, Inc.
Biomedical Advanced Research and Development Authority

Completed

Phase 1 Study of Oral QPX2015 in Healthy Adult Subjects

Bacterial Infections

Australia
Pfizer

Terminated

Efficacy, Safety and Tolerability of PF-06649751 in Parkinson's Disease Patients at Early Stage of the Disease

Parkinson Disease

United States, France, Israel, Germany
Emory University
Ortho-McNeil Janssen Scientific Affairs, LLC

Completed

Pharmacokinetic and Pharmacodynamic Evaluation of Doripenem in Critically Ill Trauma Patients

Sepsis

United States
University of Aarhus
Aarhus University Hospital; Rigshospitalet, Denmark

Completed

Adjuvant Low Dose Total Body Irradiation in Elderly Patients With Diffuse Large B-Cell Lymphoma

Non Hodgkin's Lymphoma
Calithera Biosciences, Inc

Completed

Safety and Efficacy Study of Sapanisertib in Combination With Exemestane or Fulvestrant in Postmenopausal Women With Estrogen Receptor Positive/Human Epidermal Growth Factor Receptor 2 Negative (ER+/HER2-) Metastatic Breast Cancer

Breast Cancer

United States, Belgium, France
Institut National de la Santé Et de la Recherche...
French private agencies

Completed

Primary Prevention Trial of the Health Effects of Antioxidant Vitamins and Minerals.

Healthy

France
Tasly Pharmaceutical Group Co., Ltd

Not yet recruiting

A Study of the Effectiveness and Safety of JS1-1-01 Tablet in Patients With Moderate to Severe Depression

Depression

China
Sinocelltech Ltd.

Not yet recruiting

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of a Recombinant Herpes Zoster Vaccine

Herpes Zoster

China
Ankara City Hospital Bilkent

Not yet recruiting

Comparison of Sugammadex and Sugammadex-neostigmine Combination in the Antagonism of Moderate Neuromuscular Block

Residual Neuromuscular Block | Neuromuscular Blockade Monitoring

Turkey
Pfizer

Terminated

Protonix Treatment of Maintenance of Healing in Pediatric Participants Aged 1-11 Years and 12-17 Years

Esophagitis

Bosnia and Herzegovina, United Kingdom, United States, Serbia, India, Georgia, Puerto Rico, Slovakia, Turkey (Türkiye)
Sun Yat-sen University

Active, not recruiting

KDR2-2 Suspension Eyedrop in the Treatment of Neovascular Glaucoma (KDR-NVG) Trial (KDR-NVG)

Neovascular Glaucoma | Neovascularization

China
University of Alabama at Birmingham

Terminated

CB-839 in Combination With Niraparib in Platinum Resistant BRCA -Wild-type Ovarian Cancer Patients (BRCA)

Ovarian Cancer | Resistant BRCA Wild-Type Ovarian Cancer

United States
Shiraz University of Medical Sciences

Completed

Effective Dose of Statin Post PCI

Statin Dose

Iran, Islamic Republic of
Daiichi Sankyo, Inc.

Completed

Colesevelam for Children With Type 2 Diabetes (WELKid DM)

Type 2 Diabetes Mellitus

United States
Udo Sechtem

Withdrawn

Therapeutic Effect of Sildenafil in Patients With Coronary Vasospasm

Coronary Vasospasm

Germany
Sanofi Pasteur, a Sanofi Company

Completed

Immunogenicity of High-dose Inactivated, Split-virion Influenza Vaccine Versus Standard Fluzone Vaccine in the Elderly

Influenza | Orthomyxoviridae Infection | Myxovirus Infection

United States
Wakayama Medical University

Completed

Change in Plaque Characteristics With Atorvastatin (EASY-FIT)

Atherosclerosis | Dyslipidemia | Acute Coronary Syndrome

Japan
Boehringer Ingelheim

Completed

Telmisartan in Mild to Moderate Hypertensive Patients

Hypertension
University Hospital, Tours
Astellas Pharma Inc

Unknown

Efficacy and Safety Study of a 4-Month Post-Renal Transplant Dose Reduction of Tacrolimus(ADEQUATE) (ADEQUATE)

De Novo Transplant Disease

France
University of Oxford

Completed

A Study of the Safety and Effectiveness of Two New Malaria Vaccines

Malaria

United Kingdom
Qingyuan Zhan

Not yet recruiting

Adaptive RCT of Corticosteroids for Severe Chlamydia Psittaci Pneumonia in Adults

Psittacosis
Qingyuan Zhan

Not yet recruiting

Adaptive RCT of Corticosteroids for Severe Influenza Pneumonia in Adults (CAPSTONE-IFV)

Influenza
Qingyuan Zhan

Not yet recruiting

Adaptive RCT of Corticosteroids for Severe Adenovirus Pneumonia in Adults (CAPSTONE-AD)

Adenovirus Infections, Human

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