Search clinical trials for: Dose decrease

Total 7787 results

Kala Pharmaceuticals, Inc.

Completed

Safety and Efficacy of KPI-121 in Subjects With Postsurgical Inflammation and Pain

Post Surgical Ocular Inflammation and Pain

United States
Amneal Pharmaceuticals, LLC
CBCC Global Inc.; Amneal EU, Limited

Recruiting

A Randomized, Double-blind, Parallel-group, Two-arm, Multiple Dose, Multicenter, Bioequivalence Study With Clinical Endpoint in the Treatment of Subjects With Chronic Open-angle Glaucoma or Ocular Hypertension in Both Eyes

Ocular Hypertension | Open-angle Glaucoma

United States
Simon Fraser University
University of British Columbia

Not yet recruiting

NO AD: Use of Nitric Oxide (NO) Donors for the Prevention of Autonomic Dysreflexia (AD) During Bowel Care Following SCI (NO AD)

Spinal Cord Injuries | Autonomic Dysreflexia
VA Office of Research and Development

Recruiting

High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers (VA-BAT)

Metastatic Prostate Cancer

United States
BioMarin Pharmaceutical

Active, not recruiting

An Extension Study to Evaluate Safety and Efficacy of BMN 111 in Children With Achondroplasia

Achondroplasia

United States, Australia, Japan, United Kingdom
University Hospital, Caen

Completed

Study Multicentre Evaluating the Effectiveness and Toxicity Sorafenib (Nexavar®) in Adult Patients With Uveal Melanoma and Metastatic Dissemination (O-Mel-Sora)

Uveal Melanoma

France
Dana-Farber Cancer Institute
Bristol-Myers Squibb

Terminated

A Study of Ulocuplumab And Ibrutinib in Symptomatic Patients With Mutated CXCR4 Waldenstrom's Macroglobulinemia

Waldenstrom's Macroglobulinemia

United States
Center Trials & Treatment Europe

Completed

Evaluate the Safety and Effectiveness of Intranasal Administration of Temozolomide in Patients With Glioblastoma

Gliosarcoma | Glioma, Malignant | Astrocytoma of Brain

Georgia, Bosnia and Herzegovina, Bulgaria
Bayer

Completed

Study to Assess the Safety, Tolerability, Effects on the Body, Absorption, Distribution and Elimination of 25 mg BAY2433334 in Renal Impairment Including Renal Replacement Therapy ("Dialysis")

Prevention of Thromboembolic Events

Germany
Sun Yat-sen University

Completed

A Retrospective Cohort Study: The Influence of MTHFR C677T and A1298C on the High-dose Methotrexate-Related Toxicities in Pediatric Patients With Non-Hodgkin Lymphoma

Pediatric NHL

China
University of Sao Paulo

Terminated

Treatment of Delirium in the Elderly With Donepezil: a Double-blind, Randomized, Placebo-controlled Clinical Trial

Elderly | Delirium of Unknown (Axis III) Etiology | Intensive Care (ICU) Myopathy

Brazil
Ohio State University Comprehensive Cancer Center

Completed

Velcade (Bortezomib, PS-341) and Rituximab in Relapsed/Refractory Mantle Cell and Follicular Non-Hodgkin's Lymphoma

Non-Hodgkin's Lymphoma | Mantle Cell Lymphoma

United States
Boehringer Ingelheim

Completed

Relative Bioavailability of 2 Oral Formulations of Nintedanib

Healthy

Germany
Genzyme, a Sanofi Company

Completed

A Phase 4 Study to Determine Dosing of Hectorol® Capsules When Converting From Zemplar® Injection

Secondary Hyperparathyroidism

United States
VA Pharmacy Benefits Management Strategic Healthcare...

Completed

Tolerance to Target Doses of Thiazides in Actual Practice: A Feasibility Study

Hypertension

United States
Egyptian Liver Hospital
Wadi El Nil Hospital

Completed

Randomized, Open-Label, Study to Evaluate the Safety and Efficacy of Sofosbuvir Tablet Plus Ribavirin Tablet (Part A) Versus Single Dose (2 Tablets) of EHCV Containing Sofosbuvir, Ribavirin, and Natural Anti-hemolytic (B) in Egyptian Adults With Chronic Genotype 4 HCV Infection

Hepatitis c

Egypt
Epicentre
Liverpool School of Tropical Medicine; R-Evolution Worldwide; CNRST Burkina Faso and other collaborators

Recruiting

Integrating Malaria Vaccine With Seasonal Malaria Chemoprevention in West Africa (IMVACS)

Malaria Vaccine

Burkina Faso, Mali
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Phase II Study of Moderate-dose Hypofractionated RT Combined With Pembrolizumab for HCC With Diffuse Tumor Thrombosis

Hepatocellular Carcinoma | Radiotherapy | Pembrolizumab | Tumor Thrombosis

China
Centre Jean Perrin
Ministry for Health and Solidarity, France

Active, not recruiting

AGuIX Nanoparticles with Radiotherapy Plus Concomitant Temozolomide in the Treatment of Newly Diagnosed Glioblastoma (NANO-GBM)

Glioblastoma

France
Oslo University Hospital

Active, not recruiting

A National Phase IV Study With Ipilimumab for Patients With Advanced Malignant Melanoma. (Ipi4)

Malignant Melanoma

Norway
Latin American Cooperative Oncology Group

Terminated

Neoadjuvant Durvalumab Alone Versus Durvalumab With Olaparib in Patients Ineligible for Cisplatin With Muscle-Invasive Urothelial Carcinoma of the Bladder Followed by Radical Cystectomy

Bladder Cancer | Urothelial Carcinoma

Brazil
Lahey Clinic
Brigham and Women's Hospital

Completed

Low Dose Thymoglobin in Renal Transplant Patients

Acute Renal Failure

United States
Novartis Pharmaceuticals

Completed

Pharmacodynamics, Safety, Tolerability, and Pharmacokinetics of Two Orally Inhaled Indacaterol Salts in Adult Subjects With Asthma.

Asthma

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

Regorafenib in Combination With Paclitaxel in Advanced Oesophagogastric Carcinoma (REPEAT)

Stomach Neoplasms | Neoplasm Metastasis | Esophageal Neoplasms

Netherlands
H. Lundbeck A/S
Otsuka Pharmaceutical Co., Ltd.

Completed

Brexpiprazole in Patients With Schizophrenia

Schizophrenia

Serbia, Estonia, United States, Poland, Romania, Russian Federation, Slovakia, Ukraine
ApoPharma

Completed

Absorption, Metabolism, and Excretion of a Single Dose of Ferriprox® in Patients With Sickle Cell Disease

Sickle Cell Disease

Canada
Singapore General Hospital

Completed

Study of Bortezomib and Panobinostat in Treating Patients With Relapsed/Refractory Peripheral T-cell Lymphoma or NK/T-cell Lymphoma

Angioimmunoblastic T-cell Lymphoma | Hepatosplenic T-cell Lymphoma | Peripheral T-cell Lymphoma (Not Otherwise Specified) | Extranodal NK/T-cell Lymphoma Nasal Type | Enteropathy- Type T-cell Lymphoma | Anaplastic Large Cell Lymphoma (ALCL) (ALK-1 Negative) | Relapsed ALCL (ALK-1 Positive) Post...

Singapore, Malaysia, Korea, Republic of
Hadassah Medical Organization

Unknown

C11-Erlotinib PET/CT as a Tool for Identification and Characterization of Tumor With High Expression of Epidermal Growth Factor Receptor(EGFR). (EGFR; PET/CT)

Pancreatic Cancer | Lung Cancer

Israel
Institute of Liver and Biliary Sciences, India

Completed

To Determine the Role of Prokinetics in Feed Intolerance in Critically Ill Cirrhosis

Cirrhosis

India
The University of Hong Kong
United Christian Hospital

Completed

Pre-emptive Treatments in Lupus Nephritis Patients With Serological Reactivation

Lupus Nephritis

Hong Kong
Affidea Nu-med Center of Oncological DIagnostics...

Recruiting

PRO-BOOST-LC: Whole-Gland Boost Strategies Versus SBRT Monotherapy in PSMA-Staged Localized and Locally Advanced Prostate Cancer (PRO-BOOST-LC)

Prostate Cancer (Adenocarcinoma) | Localized Prostate Cancer | Dose Escalation: Solid Tumors | Stereotactic Body Radiation Therapy (SBRT) | Prostate Brachytherapy

Poland
Yale University
National Institute on Drug Abuse (NIDA)

Recruiting

Acute Effects of THC in Older Adult (THC-Aging)

Age-related Cognitive Decline

United States
Fujian Provincial Hospital

Recruiting

Dexmedetomidine Reduces Sevoflurane MAC-BAR During Pneumoperitoneum

Laparoscopic Cholecystectomy

China
Fujian Shengdi Pharmaceutical Co., Ltd.

Recruiting

A Multicenter, Randomized, Open, Parallel-designed Study to Evaluate the Efficacy and Safety of HRS-5635 Injection Alone or in Combination With Other Agents in Patients Treated for Chronic Hepatitis B

Chronic Hepatitis B

China
Yale University
National Institute on Drug Abuse (NIDA)

Recruiting

Genetics of Cannabis Use Disorder and Cannabinoid Response in Humans

Schizophrenia | Cannabis Use Disorder

United States
Medical College of Wisconsin

Not yet recruiting

Phase I Trial of BCMA-TGF-BETA CAR-T Cells in Relapsed, Refractory Myeloma

Multiple Myeloma
University of California, San Francisco
Hayward Firefighters Local 1909 of the International Association of Firefighters

Withdrawn

Lung Cancer Screening CT for Firefighters

Lung Diseases | Lung Cancer | Lung Diseases, Interstitial | Interstitial Lung Disease | Occupational Exposure | Exposure to Pollution | Smoke Inhalation | Occupational Lung Disease | Exposure Occupational | Exposure, Inhalation

United States
SpyGlass Pharma, Inc.

Active, not recruiting

Evaluation of the Bimatoprost Implant System Used in Combination With the SpyGlass Intraocular Lens Compared to Timolol Ophthalmic Solution (Tigris)

Ocular Hypertension | Glaucoma | Cataract

United States
Chuanfu Song
Wuhu Fourth People's Hospital affiliated with Bengbu Medical University

Completed

Effects of Buspirone Combined with Clozapine

Schizophrenia

China
Clinigen, Inc.
Johns Hopkins University; M.D. Anderson Cancer Center

Terminated

HD IL-2 + Ipilimumab in Patients With Metastatic Melanoma (PROCLIVITY02)

Metastatic Melanoma

United States
GlaxoSmithKline

Completed

Respiratory Syncytial Virus (RSV) Investigational Vaccine in Infants Aged 6 and 7 Months Likely to be Unexposed to RSV

Respiratory Syncytial Virus Infections

Finland, Spain, United Kingdom, United States, Thailand, Brazil, Canada, Panama, Italy, Colombia, Mexico, Poland, Turkey
M.D. Anderson Cancer Center

Completed

Standard Dose Bevacizumab Versus Low Dose Bevacizumab Plus Lomustine (CCNU) for Recurrent Glioblastoma Multiforme (GBM)

Glioblastoma | Brain Cancer

United States
Guang'anmen Hospital of China Academy of Chinese...
Beijing Hospital; Beijing Shijitan Hospital, Capital Medical University; Gansu... and other collaborators

Completed

Zushima Plaster for Treating Knee Osteoarthritis

Osteoarthritis

China
Yale University

Terminated

A Drug Treatment for Cocaine Users Who Are Also on Methadone Maintenance Treatment

Cocaine Dependence | Opiate Dependence

United States
Zhi-Hong Liu, M.D.

Completed

An Multi-site Prospective Study to Assess the Efficacy and Safety of MMF in the Treatment of Proliferative IgA Nephropathy(IgAN)

IgA Nephropathy (IgAN)

China
Boehringer Ingelheim

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BI 653048 BS H3PO4 Capsule Multiple Rising Doses in Healthy Male Volunteers

Healthy
Trans Tasman Radiation Oncology Group
Cancer Council Queensland; Victorian Cancer Council

Completed

Chemoradiotherapy in Patients With Localised Lung Cancer

Non Small Cell Lung Carcinoma

Australia
Hunan Province Tumor Hospital

Not yet recruiting

Intrathecal Pemetrexed Combined With High-dose Furmonertinib and Beva for EGFR-m NSCLC With Leptomeningeal Metastases

Non-small Cell Lung Cancer

China
Emory University
National Cancer Institute (NCI)

Recruiting

Hypofractionated Proton Therapy for Benign Intracranial Brain Tumors, the HiPPI Study (HiPPI)

Schwannoma | Grade III Meningioma | Intracranial Neoplasm | Nerve Sheath Neoplasm | Grade II Meningioma | Grade I Meningioma | Pituitary Gland Adenoma

United States
Novavax

Completed

A Study to Evaluate the Safety and Immunogenicity of COVID-19 Vaccine and Influenza Combination Vaccine

COVID-19

Australia, New Zealand

Search clinical trials for: Dose decrease

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