Search clinical trials for: Machine learning algorithm

Total 10000 results

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Mayo Clinic

Completed

Pneumococcal Vaccines in Patients With Asthma

Asthma

United States
National Institute of Allergy and Infectious Diseases...
University of Maryland, Baltimore; Duke University; HIV Vaccine Trials Network... and other collaborators

Withdrawn

Evaluating the Safety and Immunogenicity of a Prime-boost Vaccine Regimen of GEO-D02 DNA and MVA/HIV62B With and Without B63521^11 gp120 and IHV01 gp120 Env Proteins in Healthy, HIV-uninfected Adult Participants

HIV Infections
Allena Pharmaceuticals

Completed

ALLN-346 Single Ascending Dose (SAD) Study in Healthy Volunteers (SAD)

Hyperuricemia

United States
Centers for Disease Control and Prevention, China
World Health Organization; Shandong Province Centers for Disease Control and...

Completed

A Study of Immunogenicity and Seroconversion With Sabin IPV Schedules in China.

Poliomyelitis

China
U.S. Army Medical Research and Development Command

Completed

Booster Dose (50 µg) of Recombinant Ricin Toxin Vaccine (RVEc™) in Previously Vaccinated Healthy Adults (RVEc)

Ricin Poisoning

United States
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Safety and Efficacy of Inactivated Varicella-zoster Vaccine (VZV) as a Preventative Treatment for Herpes Zoster (HZ) and HZ-related Complications in Adult Participants With Solid Tumor or Hematologic Malignancy (V212-011)

Herpes Zoster
Korea University Guro Hospital

Completed

Immunogenicity and Safety of 13-valent Pneumococcal Conjugate Vaccine Among HIV-infected Adults

HIV/AIDS | Streptococcal Pneumonia
Pfizer

Completed

A Study To Investigate A Clostridium Difficile Vaccine In Healthy Adults Aged 50 To 85 Years, Who Will Each Receive 3 Doses Of Vaccine.

Clostridium Difficile

United States, Canada
AstraZeneca

Completed

Study to Evaluate the Potential Effect of Benralizumab on the Humoral Immune Response to the Seasonal Influenza Vaccination in Adolescent and Young Adult Patients With Severe Asthma (ALIZE)

Asthma

United States
Novartis Vaccines
GlaxoSmithKline

Completed

Evaluation of Meningococcal Immune Response Among Children Who Previously Received MenACWY Conjugate Vaccine

Meningococcal Meningitis

United States
Merck Sharp & Dohme LLC

Completed

Phase III Placebo-controlled Study of V260 (RotaTeq™) in Japanese Healthy Infants (V260-029)(COMPLETED)

Gastroenteritis | Rotavirus
GlaxoSmithKline

Completed

Vaccine Efficacy Against Rotavirus Diarrhea; Vaccine Given With Routine Childhood Vaccinations in Healthy African Infants

Infections, Rotavirus

South Africa, Malawi
Sanofi Pasteur, a Sanofi Company

Completed

Persistence of Bactericidal Antibodies in Adults Who Received a Booster Dose of Menactra® Approximately 4 Years Earlier

Meningitis | Meningococcal Infections | Meningococcal Meningitis

United States
GlaxoSmithKline

Completed

Consistency of 3 Consecutive Lots of a Novel HBV Vaccine With Single-blind Safety Evaluation Using Engerix™-B as Control

Hepatitis B
Beijing Chaoyang District Centre for Disease Control...

Completed

Safety Study of Quadrivalent Influenza Virus Vaccine in Healthy People Aged 3 Years and Older

Quadrivalent Influenza Virus Vaccine

China
GSK Vaccines Institute For Global Health S.r.l.

Completed

Evaluate a New Shigella Sonnei Vaccine Administered Either by Intradermal, Intranasal or Intramuscular Route in Healthy Adults

Shigellosis

United Kingdom
Sanofi Pasteur, a Sanofi Company

Completed

Phase IV Trial to Collect Safety Data and Sera for Immunogenicity Testing in Healthy Children Given Fluzone® Vaccine

Influenza

United States
Merck Sharp & Dohme LLC

Terminated

Efficacy, Immunogenicity, and Safety of a Single Dose of V710 in Adult Patients Scheduled for Cardiothoracic Surgery (V710-003 AM2)

Bacteremia | Staphylococcus Aureus | Mediastinitis
University of Witwatersrand, South Africa

Completed

Immunogenicity and Safety of Different Dosing Schedules of Trivalent Influenza Vaccine in HIV-infected Pregnant Women

Influenza

South Africa
Karolinska University Hospital
Pfizer

Completed

PNEUMOCELL - Conjugated Pneumococcal Vaccination in Patients With Immunoglobulin G-deficiency (PNEUMOCELL)

IgG Deficiency

Sweden
University of Southern California
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Metastatic Melanoma

Intraocular Melanoma | Melanoma (Skin)

United States
Sanofi Pasteur, a Sanofi Company

Completed

Study of Inactivated, Split-Virion Influenza Vaccine Compared With the Reference Vaccine Vaxigrip® in the Elderly

Influenza | Orthomyxoviridae Infection | Myxovirus Infection

Italy, Belgium, France, Lithuania
London School of Hygiene and Tropical Medicine
Bill and Melinda Gates Foundation; Wellcome Trust

Completed

Study on the Impact of Vaccination With a Conjugate Vaccine on Meningococcal Carriage (MenAfriCar)

Meningitis

Mali, Chad, Niger
US Department of Veterans Affairs
St. Louis University

Withdrawn

MAS-1 Adjuvanted Compared to Unadjuvanted Influenza Vaccines in the Elderly (CCTA #0005)

Aged | Influenza Vaccines

United States
Eastern Virginia Medical School
Merck Sharp & Dohme LLC

Unknown

A Model for Implementation of Cervical Cancer Screening and HPV Vaccination the Emergency Department: a Pilot Study

Genital Human Papilloma Virus Infection

United States
Sanofi

Completed

Study of Different Formulations of an Intramuscular A/H5N1 Inactivated, Split Virion Influenza Adjuvanted Vaccine

Influenza | Orthomyxoviridae Infections

United States
Arizona State University

Completed

Recombinant Attenuated Salmonella Typhi Vaccine Vectors Producing Streptococcus Pneumoniae PspA

Pneumonia

United States
Shantha Biotechnics Limited
PATH

Withdrawn

Safety and Immunogenicity Study of the Recombinant Human Bovine Reassortant Rotavirus Vaccine in Healthy Indian Infants

Rotavirus Infections

India
Hamilton Health Sciences Corporation
Population Health Research Institute

Recruiting

Bleeding Reduction in Acute and Chronic Kidney Patients Having Surgery (BRACKETS) Pilot Trial (BRACKETS)

Chronic Kidney Diseases | Bleeding | Surgery | Acute Kidney Injury

Canada
National Institute of Mental Health (NIMH)

Terminated

Treatment of Menstrually Related Disorders With Continuous v. Interrupted Oral Contraceptives

Depression | Premenstrual Dysphoric Disorder | Premenstrual Syndrome | PMS | PMDD

United States
Tibotec Pharmaceuticals, Ireland

Completed

TMC435350-TiDP16-C105: Phase I, 3-way Crossover, Drug-drug Interaction Between TMC435350 and Rifampin After Multiple Dosing.

Hepatitis C | Tuberculosis | Pharmacokinetics | HCV | Rifampin
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Withdrawn

A Cytomegalovirus-Directed Vaccine (CMV-alphaDC1) for Preventing Cytomegalovirus Infection or Reactivation in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Hematopoietic and Lymphoid System Neoplasm | Cytomegaloviral Infection

United States
New York State Psychiatric Institute
National Institute on Aging (NIA)

Completed

Treating Hearing Loss to Improve Mood and Cognition in Older Adults

Depression | Hearing Loss

United States
Roya mohamed Hamad Elmaghrbi
Shofu Inc.

Not yet recruiting

Efficacy and Cost-effectiveness of Different Caries Preventive Protocols

Caries Prevention
University of Limerick
Marigot Ltd.; Enterprise Ireland

Completed

Combination Plant-Based Protein and Marine-Based Multi-Mineral Supplement and Bone Remodeling in Young Adults

Bone Resorption | Bone and Bones

Ireland
Sanofi Pasteur, a Sanofi Company

Completed

Study to Assess the Immune Response and the Safety Profile of a High-Dose Quadrivalent Influenza Vaccine (QIV-HD) Compared to a Standard-Dose Quadrivalent Influenza Vaccine (QIV-SD) in Japanese Adults 60 Years of Age and Older

Healthy Volunteers | Influenza Immunization

Japan
Novavax

Completed

Phase 3 Adolescent Study for SARS-CoV-2 rS Variant Vaccines (COVID-19)

COVID-19

United States
Beth Israel Deaconess Medical Center
National Cancer Institute (NCI); Massachusetts General Hospital; Dana-Farber... and other collaborators

Active, not recruiting

Vaccination of Patients With Ovarian Cancer With Dendritic Cell/Tumor Fusions With Granulocyte Macrophage Colony-stimulating Factor (GM-CSF) and Imiquimod

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cancer

United States
GlaxoSmithKline

Completed

Effectiveness of GlaxoSmithKline Biologicals S.A's Meningococcal Group B and Combined ABCWY Vaccines in Healthy Adolescents and Young Adults

Infections, Meningococcal

United States, Australia, Finland, Estonia, Canada, Turkey, Czechia
University Hospital, Ghent

Completed

Study of the Molecular Mechanisms Underlying the Cross-neutralizing Capacity of AS04-adjuvanted HPV Vaccine (Cervarix®) in Comparison With the Aluminiumhydroxyphosphate Sulphate Adjuvanted HPV Vaccine (Gardasil®) (HPVXneutra001)

Infection With Human Papillomavirus

Belgium
Tris Pharma, Inc.

Completed

A Trial to Evaluate the Abuse Potential of 3 Doses of GRT6005 in Adult Non-dependent Recreational Opioid Users

Abuse, Drug

Canada
University of Florida

Completed

The Effect of Short-term Atorvastatin Treatment on Immune Responses to Pneumovax 23 (StatVax)

Healthy Controls

United States
Toronto Rehabilitation Institute

Completed

Quantitative Ultrasound Response of Capsaicin (QUROC)

Central Sensitisation

Canada
Mayo Clinic

Recruiting

Folate Receptor Alpha Dendritic Cells (FRαDCs) or Placebo for the Treatment of Patients With Stage III or IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer, FAROUT Trial

Fallopian Tube Clear Cell Adenocarcinoma | Fallopian Tube Endometrioid Adenocarcinoma | Fallopian Tube Carcinosarcoma | Primary Peritoneal Carcinosarcoma | Primary Peritoneal Clear Cell Adenocarcinoma | Primary Peritoneal Endometrioid Adenocarcinoma | Advanced Fallopian Tube Carcinoma | Advanced... and other conditions

United States
National Heart, Lung, and Blood Institute (NHLBI)
National Cancer Institute (NCI); National Marrow Donor Program; Blood and Marrow...

Completed

Dendritic Cell/Myeloma Fusion Vaccine for Multiple Myeloma (BMT CTN 1401)

Multiple Myeloma

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Lustgarten Foundation; Agenus Inc.; Oncovir, Inc.

Recruiting

Comparing Neoadjuvant/Adjuvant GVAX vs a mKRASvax Given With Anti-PD-1 and Anti-CD137 for Surgically Resectable Pancreatic Cancer

Pancreatic Cancer

United States
Mario Negri Institute for Pharmacological Research
Agenzia Italiana del Farmaco

Completed

Preventing Microalbuminuria in Type 2 Diabetes (VARIETY)

Diabetes

Italy
WestVac Biopharma Co., Ltd.

Not yet recruiting

A Phase Ⅲ Clinical Trial of Recombinant COVID-19 Trivalent (XBB+BA.5+Delta) Protein Vaccine (Sf9 Cell) in Booster Vaccination

COVID-19
Sanofi

Completed

Study of a Combination Vaccine Comprised of Different Recombinant Spike Antigen Levels of a Matrix-M Adjuvanted Recombinant COVID-19 Vaccine and Recombinant Influenza Vaccine in Adult Participants 50 Years of Age and Older

Influenza Immunization | COVID-19 Immunization

United States
Sanofi Pasteur, a Sanofi Company

Completed

Study to Assess the Safety and Immunogenicity of a Single Dose of a Quadrivalent Meningococcal (MenACYW) Conjugate Vaccine in Older Adults Who Received a Primary Vaccination (3 or More Years Earlier) in Study MET49

Meningococcal Infection (Healthy Volunteers)

Puerto Rico, United States

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