Search clinical trials for: machine-learning algorithm

Total 10000 results

Boehringer Ingelheim

Completed

Bioavailability of Increasing Pramipexole Doses of Oral Extended Release (ER) Tablets in Healthy Male Volunteers

Healthy
Roswell Park Cancer Institute

Not yet recruiting

CIMAvax-EGF With KRAS G12C Inhibitor for the Treatment of Advanced, KRAS G12C Mutated Non Small Cell Lung Cancer

Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Advanced Lung Non-Small Cell Carcinoma

United States
Shanghai Institute Of Biological Products

Recruiting

A Study to Evaluate the Safety of Recombinant Herpes Zoster Vaccine for Healthy Individuals

Herpes Zoster (HZ)

China
Second Affiliated Hospital, School of Medicine,...
Hangzhou Medical Biotechnology Co., Ltd; CyTIX.Inc

Recruiting

Clinical Study of an Dendritic and Glioma Cells Fusion Vaccine With IL-12 for Treatment-naïve GBM Patients.

Glioma | Neoplasms | Glioblastoma | Neoplasms, Neuroepithelial | Neuroectodermal Tumors | Neoplasms, Nerve Tissue | Vaccines | Immunologic Factors

China
Sinovac Research and Development Co., Ltd.

Withdrawn

Efficacy,Immunogenicity and Safety of COVID-19 Vaccine , Inactivated Booster Dose in Adults Aged 18 Years and Above

COVID-19
Otsuka Pharmaceutical Development & Commercialization...
H. Lundbeck A/S

Completed

A Study of Flexible Dose Brexpiprazole as Monotherapy or Combination Therapy in the Treatment of Adults With Post-traumatic Stress Disorder (PTSD)

Stress Disorders, Post-Traumatic

United States
UbiVac
Providence Health & Services; Providence Cancer Center, Earle A. Chiles Research... and other collaborators

Completed

Pilot Study of DRibble Vaccine for Prostate Cancer Patients (DRibble)

Adenocarcinoma of the Prostate

United States
Tanta University

Recruiting

L-Carnitine Protective Effect in Nephrotoxicity (LC)

Nephrotoxicity

Egypt
Jemincare

Recruiting

Safety, Tolerability of JMKX003002 in Phase 1 Study in Healthy Subjects

Safety and Tolerability

China
Cairo University

Recruiting

Dental Photography and Numeric Shade Quantification as a Substitute to Conventional and Instrumental Shade Matching Techniques in the Esthetic Zone

Discoloration, Tooth | Chip Tooth | Non Vital Teeth | Trauma Dental

Egypt
Northwestern University
Boston Children's Hospital; Brigham and Women's Hospital; Boston Medical Center

Active, not recruiting

Vaccine Hesitancy in Black/African Americans With Rheumatic Diseases

COVID-19 | Rheumatic Diseases | COVID-19 Vaccine | SLE

United States
University of Alabama at Birmingham
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Live Attenuated Influenza Vaccine as a Nasal Model for Influenza Infection

Influenza

United States
Merck Sharp & Dohme LLC

Completed

V114 and Acute Otitis Media (V114-032/PNEU-ERA)

Acute Otitis Media (AOM)

Thailand
Jean-Michel HASCOET

Active, not recruiting

Comparison of Two Methods of Immunoprophylaxis Against RSV in Term Newborns (Abrystus)

Bronchiolitis

France
GlaxoSmithKline
Affinivax, Inc.

Completed

A Phase 2 Study to Evaluate the Safety, Tolerability, and Immune Response of AFX3772 Vaccine in Healthy Infants

Pneumococcal Infections | Pneumonia, Pneumococcal | Pneumonia, Bacterial

United States, Puerto Rico
Merck Sharp & Dohme LLC

Completed

Efficacy, Immunogenicity, and Safety Study of the 9vHPV Vaccine in Japanese Males (V503-064)

Warts, Genital | Neoplasms, Anal

Japan
University of Campinas, Brazil
Coordination for the Improvement of Higher Education Personnel; Pontifical...

Completed

Immunological Response of Bladder Cancer Patients Under BCG (IMMUNOBCG)

Bladder Cancer | Bacillus Calmette-Guerin

Brazil
GPN Vaccines

Completed

Safety, Tolerability and Immunogenicity of an Inactivated Whole-cell Pneumococcal Vaccine Gamma-PN3.

Pneumococcal Infections

Australia
Pfizer

Terminated

Vaccine-Based Immunotherapy Regimen For NSCLC and TNBC

Non-Small Cell Lung Cancer | Triple-negative Breast Cancer

United States
Norwegian Institute of Public Health
International Centre for Diarrhoeal Disease Research, Bangladesh; Sykehuset...

Completed

Effectiveness Trial to Evaluate Protection of Pregnant Women by Hepatitis E Vaccine in Bangladesh.

Hepatitis E Infection

Bangladesh
Vaxart

Completed

A Phase 1, Open-label, Safety and Immunogenicity Study of an Oral Multi-dose Administration Regimen With an Adenoviral-vector Based Tablet Norovirus Vaccine (VXA-G1.1-NN) Administered to Healthy Adult Volunteers ((VXA-G1-1-NN))

Norovirus Infections

United States
Jena University Hospital

Completed

Sequential Versus Simultaneous Pneumococcal Vaccination in Elderly: Immunological Memory and Antibody Levels

Pneumococcal Infections

Germany
GlaxoSmithKline

Completed

A Phase III Study to Assess the Lot-to-lot Consistency of GSK's Investigational RSV Maternal Vaccine and the Immune Response and Safety of RSV Maternal Vaccine When Given Alone or Co-administered With GSK's Influenza D-QIV Vaccine in Healthy Non-pregnant Women.

Respiratory Syncytial Virus Infections

Finland, Spain, Canada, United States, Korea, Republic of
Novavax

Completed

RSV F Vaccine Maternal Immunization Study in Healthy Third-trimester Pregnant Women.

Respiratory Syncytial Virus Infections

United States
Merck Sharp & Dohme LLC

Completed

Evaluation of the Safety and Immunogenicity of Sequential Administration of Prevnar 13™ and Pneumovax™ 23 in Healthy Participants 50 Years of Age and Older (V110-029)

Pneumococcal Infections
National Institute of Allergy and Infectious Diseases...

Completed

2013/2017 H7N9 Prime-Boost Interval

Influenza Immunisation | Avian Influenza

United States
Valneva Austria GmbH

Completed

Safety and Immunogenicity of the Japanese Encephalitis Vaccine IC51 (IXIARO®) in a Pediatric Population

Encephalitis

Philippines
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Withdrawn

Late Phase Administration Anakinra as a Rescue Treatment for Inhaled Allergen Challenge-Induced Airway Inflammation (LateAna)

Asthma
Gary Archer Ph.D.
National Cancer Institute (NCI)

Completed

Basiliximab in Treating Patients With Newly Diagnosed Glioblastoma Multiforme Undergoing Targeted Immunotherapy and Temozolomide-Caused Lymphopenia (REGULATe)

Malignant Neoplasms Brain

United States
GlaxoSmithKline

Completed

Assessment of Antibody Persistence in Children Previously Vaccinated With Pneumococcal Conjugate Vaccine

Streptococcus Pneumoniae Vaccines | Infections, Streptococcal

Poland
Mikhael Petrovich Kostinov
Pfizer

Completed

Clinical and Immunological Efficiency of Bacterial Vaccines at Adult Patients With Bronchopulmonary Pathology

Chronic Obstructive Pulmonary Disease | Pneumococcal Infections | Asthma

Russian Federation
University of Wisconsin, Madison
National Cancer Institute (NCI)

Completed

Two-Arm Study of a DNA Vaccine Encoding Prostatic Acid Phosphatase (PAP) in Patients With Non-Metastatic Castrate-Resistant Prostate Cancer

Prostate Cancer

United States
Eisai Inc.

Completed

BLOOM-DM: Behavioral Modification and Lorcaserin for Overweight and Obesity Management in Diabetes Mellitus

Obesity

United States
University of Nottingham
Northumbria University

Completed

Mood and Influenza Vaccine Response: A Feasibility Trial

Vaccination; Infection

United Kingdom
GlaxoSmithKline

Completed

Immunogenicity and Reactogenicity of a Booster Dose of GSK Bio's DTPa-HBV-IPV/Hib Vaccine

Hepatitis B | Tetanus | Diphtheria | Acellular Pertussis | Poliomyelitis | Haemophilus Influenzae Type b

Finland
GlaxoSmithKline

Completed

A Study in Cancer Patients to Evaluate the Effect of Lapatinib on the QTc Interval

Cancer

United States
Sanofi Pasteur, a Sanofi Company

Completed

Safety and Immunogenicity Testing of Influenza Vaccine in Healthy Children 2 Months and 6 Months of Age

Influenza

United States
Sanofi Pasteur, a Sanofi Company

Completed

Safety and Immunogenicity of the World Health Organization (WHO) Formulation of the 2004-2005 Fluzone® Vaccine

Influenza

United States
Mayo Clinic
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health... and other collaborators

Completed

Human Brain Natriuretic Peptide (BNP) (or Nesiritide) to Help Heart, Kidney and Humoral Function.

Left Ventricular Diastolic Dysfunction

United States
Statens Serum Institut
Hvidovre University Hospital; Herlev Hospital

Completed

Pneumococcal Vaccination of Crohn Patients (PneuVAC)

Crohns Disease

Denmark
The University of Texas Health Science Center,...
Bausch Health Americas, Inc.

Completed

Rifaximin, Loperamide and the Combination to Treat Travelers' Diarrhea

Travelers' Diarrhea

Mexico
Eye & ENT Hospital of Fudan University
Changhai Hospital; Shanghai Zhongshan Hospital; Fujian Medical University Union... and other collaborators

Recruiting

Adjuvant vs Surgery Only in Early-stage Recurrent NPC

Recurrent Nasopharyngeal Carcinoma

China
Queen Mary University of London
Takeda Pharmaceuticals International, Inc.

Recruiting

SIZOMUS Safety of Ixazomib Targeting Plasma Cells in Multiple Sclerosis (SIZOMUS)

Relapsing Remitting Multiple Sclerosis | Primary Progressive Multiple Sclerosis | Secondary Progressive Multiple Sclerosis

United Kingdom
Nantes University Hospital

Active, not recruiting

Evaluation of the Diagnostic Performance of Dynamic Myocardial Perfusion Scintigraphy in Comparison With Invasive Intracoronary FFR Measurement, in the Assessment of Significant Residual Coronary Stenosis After Acute Coronary Syndrome: Dyna-MI Pilot Study. (Dyna-MI)

Myocardial Infarction

France
Washington University School of Medicine
AstraZeneca; Gateway for Cancer Research

Active, not recruiting

Personalized Neoantigen Vaccine in Combination With Durvalumab (MEDI4736) in Extensive Stage Small Cell Lung Cancer

Extensive-stage Small Cell Lung Cancer

United States
Ultimovacs ASA
Oslo University Hospital

Completed

A Phase I/IIa Study of UV1 Vaccination in Patients With Non Small Cell Lung Cancer. (UV1-hTERT2012L)

Non-small Cell Lung Cancer

Norway
Ultimovacs ASA

Completed

A Phase I/IIa Study of UV1 Vaccine in Patients With Prostate Cancer (UV1/hTERT2012P)

Prostate Cancer

Norway
NantBioScience, Inc.

Terminated

QUILT-3.013: Study of Ad5 [E1-, E2b-]-HER2/Neu Vaccine (ETBX-021) in Subjects With Unresectable Locally Advanced or Metastatic HER2-Expressing Breast Cancer

Cancer

United States
Ministry of Public Health, Argentina
Centers for Disease Control and Prevention; Pan American Health Organization

Active, not recruiting

Immunogenicity of Yellow Fever Vaccine in a Pediatric Population Vaccinated at 12-23 Months of Age in Argentina

Yellow Fever

Argentina
Centers for Disease Control and Prevention
Southcentral Foundation; Alaska Native Tribal Health Consortium

Completed

Immunogenicity and Reactogenicity of Pneumococcal Polysaccharide and Conjugate Vaccines in Native Elders

Pneumococcal Infections

United States

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