Search clinical trials for: decrease of sedation doses and switch of ventilator settings

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University of Aberdeen
NHS Grampian

Recruiting

Rebalancing the Fat Content of the Heart and Muscles (Re-CHARM)

Diabetes Mellitus Type 2

United Kingdom
GlaxoSmithKline

Withdrawn

Effectiveness of Fluticasone Furoate/ Umeclidinium/ Vilanterol (FF/UMEC/VI) Using the Connected Inhaler System (CIS) as Compared With Fluticasone Proprionate/ Salmeterol (FP/SAL) Plus Tiotropium (TIO) in Inadequately Controlled Asthma

Asthma
Dartmouth-Hitchcock Medical Center

Completed

A Study of Quetiapine and Mirtazapine for the Treatment of Alcohol Dependency

Alcohol Dependence

United States
GlaxoSmithKline

Withdrawn

A Study Comparing the Closed Triple Therapy, Open Triple Therapy and a Dual Therapy for Effect on Lung Function in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Canada, Germany
ALK-Abelló A/S
Merck Sharp & Dohme LLC

Completed

Efficacy and Safety Study of SCH 900237/MK-8237 in Children and Adults With House Dust Mite-Induced Allergic Rhinitis/Rhinoconjunctivitis (P05607)

Rhinitis, Allergic, Perennial | Rhinitis, Allergic, Nonseasonal
Janssen Sciences Ireland UC

Completed

A Bioequivalence Study of Darunavir, Emtricitabine, and Tenofovir Alafenamide, in the Presence of Cobicistat in Healthy Participants

Healthy

Netherlands
Pfizer

Withdrawn

A Study on 2 Different Combination Tablets of Nirmatrelvir Plus Ritonavir to Compare Them With Marketed Paxlovid in Healthy Participants

Healthy Participants | Biological Availability
GlaxoSmithKline

Completed

Phase 2a, AMP Challenge, Dose Escalation Study to Assess the Dose Response for Topical Efficacy and Systemic Activity in Asthmatic Subjects

Asthma

United Kingdom, Germany
Universitätsklinikum Hamburg-Eppendorf

Completed

Auto-Allo Tandem Stem Cell Transplantation for Patients With Multiple Myeloma

Multiple Myeloma

Germany
Sixth Affiliated Hospital, Sun Yat-sen University

Completed

Dexmedetomidine Versus Propofol for Sedation During Awake Endotracheal Intubation

Intubation | Sedation

China
The Hong Kong Polytechnic University

Completed

Auricular Acupressure for Chemotherapy-Induced Nausea and Vomiting in Female Breast Cancer Patients

Breast Neoplasms | Nausea | Vomiting

China
Seoul National University

Recruiting

Feasibility of Lower-Body EMS Combined With Resistance Training in Postmenopausal Women: A Pilot Randomized Controlled Trial (LB-EMS-Pilot)

Body Composition | Resistance Exercise | Autonomic Function | Post Menopausal

South Korea
Peking University Third Hospital

Recruiting

Safety and Effectiveness of No-touch Technique for Ascending Aorta in MICS-CABG

Coronary Artery Bypass Grafting | Off-pump Coronary Artery Bypass | Minimally Invasive Cardiac Surgery | Coronary Arterial Disease (CAD)

China
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Zanubrutinib Combined With G-CVP in Previously Untreated FL

Follicular Lymphoma ( FL)

China
University of Alabama at Birmingham

Completed

Increasing Naloxone Access for Persons Who Use Opioids

Naloxone

United States
Memorial Sloan Kettering Cancer Center

Completed

Humanized 3F8 Monoclonal Antibody (Hu3F8) When Combined With Interleukin-2 in Patients With High-Risk Neuroblastoma and GD2-positive Solid Tumors

Neuroblastoma

United States
Mahidol University

Completed

Effect of Bilateral Quadratus Lumborum Block for Pain Relief in Patients With Cesarean Section

Caesarean Section | Analgesia | Spinal Anesthesia | Quadratus Lumborum Block

Thailand
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Postmarketing Study of the Risk of Venous Thromboembolism (Blood Clots), Myocardial Infarction (Heart Attacks), and Stroke Among Women Using ORTHO EVRA (Norelgestromin and Ethinyl Estradiol Contraceptive Patch) Compared With Women Who Take Oral Contraceptives for Birth Control

Female Contraception | Contraception
Sheba Medical Center

Unknown

Intravesically Heated Thermo-chemotherapy With Mitomycin-C Prior to TURBT

Transitional Cell Carcinoma

Israel
All India Institute of Medical Sciences, New Delhi
University of Bergen

Completed

Micronutrient Supplementation in in Paediatric Pulmonary Tuberculosis (ICTBSG)

Tuberculosis

India
National Taiwan University Hospital
Taipei Veterans General Hospital, Taiwan; National Cheng-Kung University Hospital

Completed

Low-dose RAD001(Everolimus) Plus Cisplatin-HDFL Chemotherapy for the First-line Treatment of Advanced Gastric Cancer

Metastatic Gastric Cancer

Taiwan
Hospital Israelita Albert Einstein
Colgate Palmolive

Completed

Salivary SARS-CoV-2 Load of Covid-19 Patients After Oral Antimicrobial Solutions and Dentifrices

Corona Virus Infection

Brazil
Minia University

Completed

Quadratus Luborum Block Using Bupivacaine Versus Bupivacaine-Dexamethasone in Laparoscopic Cholecystectomy

Post Operative Pain

Egypt
Merck Sharp & Dohme LLC

Terminated

A Study of the Pharmacokinetics and Safety of MK-8808 (MK-8808-002)

Rheumatoid Arthritis
Jessa Hospital

Completed

Effect of Virtual Reality (VR) Therapy on Patients Undergoing Hand Surgery Under Ultrasound-guided Regional Anesthesia

Anesthesia, Local | Surgery | Hand Injuries

Belgium
Kasr El Aini Hospital

Recruiting

The Efficacy of Intravenous Dexamethasone on the Duration of Analgesia of Ultrasound Guided Axillary Brachial Plexus Block in Pediatric Patients Undergoing Below Elbow Orthopaedic Surgeries

Axillary Brachial Plexus Block

Egypt
Cairo University

Not yet recruiting

Preoperative Pregabalin vs Gabapentin in Elderly Undergoing Surgry,Controlled Trial

Anxiety | Anxiety Disorder (Panic Disorder or GAD)

Egypt
Convalife (Shanghai) Co., Ltd.

Not yet recruiting

Nilatinib Maleate Tablets Combined With Capecitabine in the Treatment of HER2-positive Advanced Esophageal/Esophagogastric Junction/Gastric Adenocarcinoma With Brain Metastases

Her2-positive Advanced Esophageal/Esophagogastric Junction/Gastric Adenocarcinoma With Brain Metastasis
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Temozolomide for Injection Combined With Epirubicin in First-line Treatment of Leiomyosarcoma

Leiomyosarcoma

China
Bio-Path Holdings, Inc.

Recruiting

A Clinical Trial of BP1002 in Patients With Refractory/Relapsed Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia, in Relapse | Acute Myeloid Leukemia Refractory

United States
Hunan Province Tumor Hospital

Recruiting

Erlotinib Combined With Chemotherapy in TKI Resistant Non-Small Cell Lung Cancers

Carcinoma, Non-Small Cell Lung | EGFR Gene Mutation

China
PT Bio Farma
Hasan Sadikin General Hospital

Withdrawn

Immunogenicity and Safety of DTP-HB-Hib Using New Hepatitis B Bulk (Bio Farma)

Diphtheria Vaccine Adverse Reaction | Tetanus Vaccine Adverse Reaction | Pertussis Vaccine Adverse Reaction | Haemophilus Influenzae Type B Vaccine Adverse Reaction | Hepatitis B Vaccine Adverse Reaction

Indonesia
University of Novi Sad

Completed

Caudal Block for Inguinal Hernioplasty in Children

Postoperative Pain

Serbia
Shire
Halozyme Therapeutics

Completed

A Study to Evaluate the Safety and Pharmacology of Subcutaneous Administration of CINRYZE With Recombinant Human Hyaluronidase

Hereditary Angioedema

United States
Shire

Completed

Subcutaneous CINRYZE With Recombinant Human Hyaluronidase for Prevention of Angioedema Attacks

Hereditary Angioedema (HAE)

United States, Germany, Spain, Sweden
Teva Pharmaceuticals USA

Withdrawn

An Open-Label, Single-Center Study to Evaluate the Exposure-Response Relationship Between the Plasma Drug Concentrations and the Change From Baseline in QTc at Steady State Following Once-daily Administration of CASSIPA® in Opioid Dependent Subjects.

Evaluation of QTc Interval
Hospital de Clinicas de Porto Alegre

Completed

Postoperative Urinary Retention in Orthopedic Patients

Urinary Retention | Orthopedic Procedures | Nerve Block | Anesthesia, Spinal
University Hospital, Basel, Switzerland

Completed

Anti-EGFR Immunoliposomes in Solid Tumors

Solid Tumors

Switzerland
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

Carmustine Implants and O(6)-Benzylguanine in Treating Children With Recurrent Malignant Glioma

Brain and Central Nervous System Tumors

United States
Kholoud Usama

Recruiting

Comparison Between Erector Spinae Plane Block Versus Serratus Anterior Plane Block Regarding Analgesia Post Modified Radical Mastectomy (FMASUMD66/2025)

Breast Cancer | Modified Radical Mastectomy

Egypt
University of Calgary

Not yet recruiting

Diltiazem Ointment With Lidocaine vs. Nifedipine Ointment With Lidocaine Ointment for Treatment of Chronic Anal Fissure

Rectal Diseases | Fissure in Ano | Rectal Bleed

Canada
Viatris Specialty LLC

Completed

Study Evaluating Abuse Potential of Lyrica® in Healthy Non-Drug Dependent Recreational Opioid Users

Abuse Potential

United States
University of Salerno

Not yet recruiting

Efficacy and Safety of Bempedoic Acid in Association With Anti-PCSK9 and Ezetimibe in Statin-intolerant Patients (BESAFE)

Cardiovascular Diseases | Dyslipidemias | Lipid Metabolism Disorders | Statin Adverse Reaction
LifeBridge Health

Unknown

Gel-Sinuplasty for Chronic Rhinosinusitis With and Without Nasal Polyposis

Chronic Sinusitis | Nasal Polyps | Chronic Sinusitis, Ethmoidal | Chronic Sinusitis, Sphenoidal | Chronic Sinusitis - Frontoethmoidal | Chronic Sinusitis - Ethmoidal, Posterior | Chronic Sinusitis - Ethmoidal Anterior | Nasal Polyp - Posterior

United States
Ankara University

Completed

Intrathecal Morphine for Inguinal Hernia Repair.

Nausea | Vomiting | Postoperative Pain | Inguinal Hernia | Pruritus

Turkey
National Cancer Institute, Egypt

Completed

Dexmedetomidine vs Dexamethasone as Adjuvant to Bupivacaine in Bilevel Erector Spinae Plane Block in Breast Surgeries

Analgesia

Egypt
Brno University Hospital
Masaryk University

Completed

Perioperative Analgesia in Neonates Who Underwent Primary Cleft Lip Repair Surgery

Perioperative Analgesia in Neonates

Czechia
Enzyvant Therapeutics GmBH
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Thymus Transplantation Dose in DiGeorge #932

DiGeorge Syndrome | DiGeorge Anomaly | Complete DiGeorge Anomaly | Complete DiGeorge Syndrome

United States
Merve Erkmen Almaz

Completed

Effectiveness Fluoride Varnishes in Children With Early Childhood Caries

Early Childhood Caries
CHFDX,Inc.
University of South Florida; Tampa General Hospital

Recruiting

Observational Study Designed to Detect Decompensation of Congestive Heart Failure (dCHF) Using a Non-Invasive Wearable Device

Decompensated Chronic Heart Failure

United States

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