Search clinical trials for: Adaptive study design

Total 121178 results

Cardresearch

Recruiting

A Multicenter, Adaptive, Randomized, doublE-blinded, Placebo-controlled Study in Participants With Long COVID-19: The REVIVE Trial (REVIVE)

Chronic Fatigue Syndrome | Long COVID-19 Syndrome

Brazil
Fudan University

Not yet recruiting

An Adaptive-design Prospective Cohort Study of Watch and Wait Strategy in Patients With Locally Advanced Rectal Cancer

Rectal Cancer

China
Columbia University
Emergency Medicine Foundation; Mailman School of Public Health

Completed

Dose-Finding Study of Intranasal Midazolam for Procedural Sedation in Children

Procedural Anxiety

United States
Novartis Pharmaceuticals

Completed

An Open-label, Adaptive Design, Positron Emission Tomography Study in Healthy Male Participants to Characterize Receptor Occupancy by MIJ821 in the Brain

Major Depressive Disorder

United Kingdom
DermBiont, Inc.
Zepeda Dermatologia

Active, not recruiting

Adaptive Design Study for Safety and Efficacy of Treatment Regimens With SM-020 in Subjects With Seborrheic Keratosis

Seborrheic Keratosis

El Salvador
Novartis Pharmaceuticals

Terminated

Study of Safety and Efficacy of Tropifexor (LJN452) in Patients With Non-alcoholic Steatohepatitis (NASH) (FLIGHT-FXR)

Non-alcoholic Steatohepatitis (NASH)

Belgium, Germany, Taiwan, Austria, United States, Spain, Korea, Republic of, Argentina, Australia, Italy, Japan, Singapore, Netherlands, Slovakia, France, Canada, India
Wave Neuroscience

Completed

Adaptive Design Study of NEST sTMS in Subjects With Major Depressive Disorder

Depressive Disorder | Depression | Depressive Disorder, Major | Major Depressive Disorder | Depressive Episode

United States
University of Kansas Medical Center
Ohio State University; Nationwide Children's Hospital; University of Cincinnati

Completed

Assessment of DHA On Reducing Early Preterm Birth (ADORE)

Preterm Birth

United States
Novartis Pharmaceuticals

Completed

Adaptive-design Dose Finding Study to Assess the Antiviral Efficacy and Safety of NIM811 Administered in Combination With Standard of Care (SOC) in Relapsed Hepatitis C Virus 1 (HCV-1) Infected Patients

Chronic Hepatitis C Genotype-1 Relapse

Belgium, United States, Germany, Spain, Puerto Rico, Taiwan, Australia
Liverpool John Moores University
University College, London; Duke-NUS Graduate Medical School; Applied Behaviour...

Unknown

A Digital Approach to Improving Carbohydrate Periodisation Behaviours in Athlete: SMART+ Study

Diet Habit

United Kingdom
Eisai Inc.

Completed

A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group, Bayesian Adaptive Randomization Design, Dose Response Study of the Efficacy of E2006 in Adults and Elderly Subjects With Chronic Insomnia

Elderly | Chronic Insomnia | Adults

United States
GlaxoSmithKline

Completed

Dose-Ranging Study of GSK2140944 in the Treatment of Subjects With Suspected or Confirmed Gram-Positive Acute Bacterial Skin and Skin Structure Infections

Infections, Bacterial

United States
GlaxoSmithKline

Terminated

An Adaptive Phase II Study to Evaluate the Efficacy, Pharmacodynamics, Safety and Tolerability of GSK2586184

Systemic Lupus Erythematosus

Estonia, Germany, South Africa, Peru, Sweden, France, Korea, Republic of, Hong Kong, Spain, Romania, Czechia, Argentina, Chile, Hungary, Greece, Poland
Medicus Research, LLC

Completed

DEC033 Study Product for Mild to Moderate Eczema An Open-label, Adaptive-design Pilot Study

Eczema
Clinical Research Management, Inc.
Duke University; Bill and Melinda Gates Foundation; Syneos Health; University of... and other collaborators

Unknown

Multiple Treatments for Ebola Virus Disease (EVD)

Ebola Virus Disease
Richmond Pharmacology Limited

Completed

Food and Insulin Effect on QT/QTC Interval of ECG (C11035)

Effects of Different Meals on the QT/QTc Interval | Insulin and Oral Hypoglycemic [Antidiabetic] Drugs Causing Adverse Effects in Therapeutic Use | C-Peptide Effects on the QT/QTc Interval | Moxifloxacin ECG Profile in Fed and Fasted State | Japanese vs. Caucasian TQT Comparison

United Kingdom
Ono Pharmaceutical Co. Ltd

Completed

A Phase I Study to Evaluate Safety, Tolerability and Pharmacokinetics of ONO-4053 in Healthy Volunteers

Healthy Adult Subjects

United Kingdom
National Dental Centre, Singapore

Not yet recruiting

Implementation of Digital Workflow for Complete Dentures - A Crossover Study

Complete Edentulism
AbbVie

Recruiting

An Observational Study to Assess Next Generation Emulsion Preservative Free Eye Drops (NGE-UD) on Dry Eye Symptoms and Quality of Life of Adult Participants With Mild to Moderate Dry Eye Disease (DED)

Dry Eye

United States
Fujian Shengdi Pharmaceutical Co., Ltd.

Not yet recruiting

A Multicenter, Randomized, Open, Parallel-designed Study to Evaluate the Efficacy and Safety of HRS-5635 Injection Alone or in Combination With Other Agents in Patients Treated for Chronic Hepatitis B

Chronic Hepatitis B

China
Fateme Moshirenia
Tarbiat Modarres University

Not yet recruiting

Rationale and Design of Diabetes Management With Curcumin and Saffron (DMCS): a Randomised, Three Blind -Blind, Placebo-controlled Study

Diabetes Mellitus | Women of Reproductive Age
University of Kansas Medical Center
Continuum Educational Technologies

Not yet recruiting

iMRI Prone Positioning Frame Design Feasibility Study

Epilepsy | Pulmonary Embolism

United States
Akdeniz University

Recruiting

Program of Health Behaviour Against to Cancer (PHeBAC) (PHeBAC)

Parents | Health Behavior | Disabilities Mental | Mothers | Cancer Screening | Cancer Prevention | Disability, Intellectual | Experimental Study Designs

Turkey
Designs for Health

Recruiting

A Pilot Study of a Commercially-available Oil Rinse Product (PerioPull™) on Markers of Dental Health

Oral Health

United States
Icahn School of Medicine at Mount Sinai

Recruiting

A Light Exposure Tracker Designed to Improve Circadian Rhythms - Aim 1

Mild Cognitive Impairment | Alzheimer's Disease

United States
University of South Florida
Center for Smart Use of Technologies to Assess Real-world Outcomes

Not yet recruiting

Effects of Recursive Self-feedback on Speech Production in Aphasia

Stroke | Aphasia
Royal College of Surgeons, Ireland

Not yet recruiting

Supporting Secondary School Student Wellbeing Through a Mobile App and Wearable Biofeedback (EWSSS)

Stress Psychological | Overall Wellness | No Disease or Condition is Being Studied
University of South Florida

Not yet recruiting

Novel Adaptive Cognitive Training in Autistic Adults With Co-occurring Insomnia

Insomnia | Autism Spectrum Disorder
Beijing 302 Hospital

Recruiting

Clinical Trial of Metal-Reinforced Teeth Designed for Endoscopic Clips

Pilot Study | Clips

China
University of Texas Southwestern Medical Center

Recruiting

A Study of Amantadine for Cognitive Dysfunction in Patients With Long-Covid

Long COVID | Post-Acute COVID-19 Syndrome

United States
Tianjin Eye Hospital
Beihang University

Recruiting

A Study of Artificial Intelligence Assisted Small Incision Lenticule Extraction (SMILE) for Surgical Design and Influencing Factors

Myopia | Myopic Astigmatism

China
University of Cadiz
Ministerio de Ciencia e Innovación, Spain

Not yet recruiting

Physical Exercise, Diet, and Health in People With Type 2 Diabetes: Longitudinal Design of the EDUGUTION Study

Cardiovascular Diseases | Diabetes Mellitus, Type 2 | Fat Burn | Metabolism Disorder
Xijing Hospital

Recruiting

Retrospective Study of the Effects of Sub-pathologic Phenotypes of BP on Clinical Management and Prognosis (BP)

Bullous Pemphigoid

China
Cardiff University

Not yet recruiting

Evaluating an ACT Self-help Book for University Students

Well-Being, Psychological

United Kingdom
West China Hospital

Not yet recruiting

Study of Adaptive Radiotherapy for High-grade Glioma Based on Interfraction MRI

High-grade Glioma

China
University of Washington
National Institutes of Health (NIH); National Institute on Deafness and Other...

Recruiting

Behavioral and Neural Characteristics of Adaptive Speech Motor Control

Speech

United States
University of North Carolina, Chapel Hill
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

UNCPM 22314 - Pregnancy, Infant and Maternal Health Outcomes Study (PrIMO)

Pregnancy Related | HIV Prevention | Pre-exposure Prophylaxis

Malawi
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Phase I Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes for Advanced HER2-Negative Breast Cancer

Breast Neoplasms

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Phase I Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes as Neoadjuvant Therapy for HER2-Negative Breast Cancer

Breast Neoplasms

China
Stephen Ruedrich
Neurocrine Biosciences

Not yet recruiting

Valbenazine Treatment of Tardive Dyskinesia in Adults With Intellectual/Developmental Disabilities (TD-AIDD)

Intellectual Disability | Developmental Disabilities | Tardive Dyskinesia

United States
Boehringer Ingelheim

Recruiting

A Study to Test the Effect of Survodutide (BI 456906) on Cardiovascular Safety in People With Overweight or Obesity (SYNCHRONIZE™ - CVOT)

Obesity

United States, Korea, Republic of, Belgium, Australia, United Kingdom, Mexico, Spain, Germany, Taiwan, Netherlands, Brazil, Hungary, Denmark, Canada, Poland, Austria, China, Finland, Greece, Italy, Hong Kong, Czechia, Portugal, Saudi... and more
Vastra Gotaland Region
Göteborg University

Recruiting

Adaptive Mechanisms In GRown up ObeSity Study (AMIGROS) (AMIGROS)

Obesity | Type 2 Diabetes

Sweden
Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator...

Not yet recruiting

Pharmacogenomics IND EXEMPT SNP Clinical Study - Crizotinib and Single Nucleotide Polymorphisms (Drugs-SNPs)

Non-Small Cell Lung Cancer

United States
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

A Study of Adipose Tissue in Adaptive Responses to Exercise

Healthy | Obesity

United States
Spanish National Research Council
Andalusian Health Service; Universidad Pablo de Olavide

Recruiting

Oleanolic Acid as Therapeutic Adjuvant for Type 2 Diabetes Mellitus (OLTRAD STUDY) (OLTRAD)

Type II Diabetes Mellitus | Diabetic Patients

Spain
University of Washington
Cystic Fibrosis Foundation

Recruiting

Lung Transplant READY CF 2: CARING CF Ancillary RCT

Cystic Fibrosis

United States
University of Washington
National Institute of Nursing Research (NINR)

Recruiting

Lung Transplant READY CF 2: A Multi-site RCT

Cystic Fibrosis

United States
Aurelia Hospital

Not yet recruiting

Impact of Renal Denervation in Patients With Coronary Microvascular Dysfunction: Study Design and Rationale (IMPRESSION)

Coronary Microvascular Dysfunction | Resistant Hypertension | Hypertensive Heart Disease
Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator...

Not yet recruiting

Pharmacogenomics IND EXEMPT SNP Clinical Study - Alectinib and Single Nucleotide Polymorphisms (Drugs-SNPs)

Non-small Cell Lung Cancer

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes as Neoadjuvant Therapy for HER2-Negative Breast Cancer

Breast Neoplasms

China

Search clinical trials for: Adaptive study design

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