Search clinical trials for: Biologic response

Total 19792 results

Nanfang Hospital, Southern Medical University

Recruiting

Research on the Mechanisms of Treatment Non-response in Inflammatory Bowel Disease Based on Multi-omics Technology

Inflammatory Bowel Diseases

China
Ohio State University Comprehensive Cancer Center

Not yet recruiting

Ketogenic Dietary Intervention to Improve Response to Immunotherapy in Patients With Metastatic Melanoma and Metastatic Kidney Cancer

Metastatic Renal Cell Carcinoma | Metastatic Cutaneous Melanoma | Stage IV Renal Cell Cancer AJCC v8 | Clinical Stage IV Cutaneous Melanoma AJCC v8

United States
University of Nottingham
Biotechnology and Biological Sciences Research Council

Recruiting

Multi-organ Responses to CHronic Physical Activity and INactivity (CHAIN)

Metabolic Syndrome | Sedentary Behavior | Age-related Cognitive Decline | Age-Related Sarcopenia

United Kingdom
Gruppo Italiano Malattie EMatologiche dell'Adulto

Not yet recruiting

Biological and Clinical Efficacy of Shingrix in Patients With CLL

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma | CLL-like MBL | Varicella-zoster Virus Reactivation

Italy
Mayo Clinic

Recruiting

Predicting Response to Immune Checkpoint Inhibitors Across Solid Tumors Using a Live Tumor Diagnostic Platform (CYBRID-04)

Metastatic Lung Non-Small Cell Carcinoma | Metastatic Clear Cell Renal Cell Carcinoma | Resectable Lung Non-Small Cell Carcinoma | Metastatic Malignant Solid Neoplasm | Metastatic Bladder Urothelial Carcinoma | Metastatic Colorectal Carcinoma | Metastatic Triple-Negative Breast Carcinoma | Locally... and other conditions

United States
Centre Hospitalier Universitaire de Besancon

Not yet recruiting

Antitumor T Cell Responses in Patients With Bladder Cancer (immunoBLAD)

Bladder Cancer
GlaxoSmithKline

Recruiting

A Study on the Immune Response and Safety of Inactivated Poliovirus Vaccine (IPV) When Co-administered With Human Rotavirus (HRV) Porcine Circovirus (PCV)-Free Vaccine in Healthy Chinese Infants

Gastroenteritis

China
Washington State University
National Institute on Alcohol Abuse and Alcoholism (NIAAA); Weill Medical College... and other collaborators

Not yet recruiting

Virtual Incentive Treatment for Alcohol (VITA)

Alcohol Drinking | Alcohol Dependence | Alcohol Use Disorder | Alcohol Abuse

United States
Sanofi

Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab on Background Topical Corticosteroids Therapy in Participants Aged 12 Years and Older With Moderate-to-severe AD Who Have Had an Inadequate Response to Prior Biologic Therapy or an Oral JAK Inhibitor (AQUA)

Dermatitis Atopic

Chile, United Kingdom, United States, Canada, Turkey, Israel, Korea, Republic of
Institut Claudius Regaud
NovoCure Ltd.

Not yet recruiting

Study of Biologic Tumor and Plasma Biomarkers of Response to TTFields in Patients Treated for Newly Diagnosed Glioblastoma (EXOFIELDS)

Glioblastoma

France
University of Wisconsin, Madison
National Institute of Mental Health (NIMH)

Recruiting

Response to Acute Exercise in Eating Disorders

Eating Disorders

United States
Instituto de Ciencia y Tecnología de Alimentos...
Ministry of Science and Innovation

Recruiting

Interindividual Variation in Response to Green Coffee (GREENCOF)

Overweight and Obesity

Spain
LimmaTech Biologics AG
GlaxoSmithKline

Recruiting

Assessing the Safety, Immune Response, and Early Efficacy of a Candida Vaccine in Women With Recurrent Vulvovaginal Candidiasis: A Randomized Controlled Study

Recurrent Vulvovaginal Candidiasis

Belgium
University of Washington
Breast Cancer Research Foundation

Not yet recruiting

Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Metastatic HER2-Negative Breast Carcinoma | Metastatic Hormone Receptor-Positive Breast Carcinoma | Locally Advanced Unresectable HER2-Negative Breast Carcinoma | Locally Advanced Unresectable Hormone Receptor-Positive...

United States
Royal College of Surgeons, Ireland

Not yet recruiting

Neck Posturing in Surgeons During Microsurgery Procedures Using Upright Go 2 Device

Neck Pain Musculoskeletal
City of Hope Medical Center
National Cancer Institute (NCI)

Not yet recruiting

Immune Response Activation for the Treatment of Unresectable Metastatic Colorectal Cancer or CEA Positive Metastatic Breast Cancer

Breast Carcinoma | Colorectal Carcinoma

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Evaluation of Anti-PD-1 Therapy by Monitoring T Cell Responses in Melanoma, Lung and Other Cancer Types

Metastatic Melanoma | Stage III Lung Cancer AJCC v8 | Metastatic Lung Carcinoma | Stage IV Lung Cancer AJCC v8 | Locally Advanced Malignant Solid Neoplasm | Locally Advanced Melanoma | Metastatic Malignant Solid Neoplasm | Clinical Stage III Cutaneous Melanoma AJCC v8 | Clinical Stage IV Cutaneous Melanoma... and other conditions

United States
Fondazione Italiana Linfomi - ETS

Recruiting

Prospective Biological Study to Evaluate the Persistence of COVID-19 Vaccine and Other Vaccines'-Induced Immune Responses in Follicular Lymphoma Patients Undergoing Frontline Induction Immuno-chemotherapy and Anti-CD20 Maintenance (FIL_FollVax22)

Follicular Lymphoma

Italy
Exscientia GmbH
AGO Research GmbH

Recruiting

Association of Ex Vivo Drug Response (EVDR) and Clinical Outcome in Ovarian Cancer (EXCYTE-1)

Epithelial Ovarian Cancer

Austria, Germany
Royal College of Surgeons, Ireland
New York University; The Charitable Infirmary Charitable Trust

Not yet recruiting

This is a 6-month Observational Study. Patients Included Will be Those Referred With a Possible Diagnosis or an Established Diagnosis of Asthma. It Will Look at the Association of the Asthma Microbiome and Disease Characteristics, Severity and Treatment Response.

Asthma
Emory University

Recruiting

Systems Biological Assessment of Statin Effect on Vaccine Responses

Vaccine Response

United States
UNC Lineberger Comprehensive Cancer Center

Recruiting

Brain Slice Explants to Predict Drug Response in Brain Tumors

Central Nervous System Tumor

United States
Innovent Biologics (Suzhou) Co. Ltd.

Recruiting

A Study of IBI112 in Chinese Patients With Psoriasis Who Were Previously Treated With Biologics

Psoriasis

China
OHSU Knight Cancer Institute
Oregon Health and Science University; Progenics Pharmaceuticals, Inc.

Not yet recruiting

Evaluation of the Change in PSMA Expression in Prostate Cancer in Response to Hormonal Therapy

Prostate Adenocarcinoma | Castration Resistant Prostate Cancer | Castration Sensitive Prostate Cancer

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Early Stage Triple-Negative Breast Carcinoma

United States, Puerto Rico
Emory University
Defense Advanced Research Projects Agency

Recruiting

Systems Biological Assessment of the Durability of Vaccine Responses (DARPASB)

Vaccine Response

United States
Istituto Auxologico Italiano

Recruiting

Potential Predictive Biological Markers of Major Depression Response to Citalopram Therapy in Anorexia Nervosa. (ANCITA)

Anorexia Nervosa

Italy
Aristotle University Of Thessaloniki
1st ORL Department, AHEPA Hospital, Aristotle University of Thessaloniki; Department... and other collaborators

Recruiting

Biomarkers of Response to Mepolizumab Treatment in Patients With Nasal Polyps With or Without Bronchial Asthma (CALIOPI)

Asthma | Chronic Rhinosinusitis With Nasal Polyps

Greece
University of Missouri-Columbia

Recruiting

Biological Response to Platelet-rich Plasma and Corticosteroid Injections

Knee Osteoarthritis

United States
King's College London
Guy's and St Thomas' NHS Foundation Trust; Biotechnology and Biological Sciences... and other collaborators

Recruiting

Individual Variability of Experimental Gingivitis Response

Gingivitis | Oral Disease

United Kingdom
Harvard School of Public Health (HSPH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Dietary Biomarkers Intervention Core

Diet, Healthy | Biological Markers | Nutrition, Healthy | Metabolomics

United States
Assiut University

Not yet recruiting

The Role of Intestinal Ultrasound in Monitoring the Response to Biological Therapy in Patients With Ulcerative Colitis

Ulcerative Colitis
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Multi-omics to Predict Responses to Biologics in IBD (MORE)

Crohn Disease | Ulcerative Colitis

China
University Hospital, Montpellier

Recruiting

Mepolizumab Pharmacokinetics Among Patients With Severe Asthma (CESAM)

Asthma

France
National Research Centre, Egypt
Theodor Bilharz Research Institute; The holding company for biological products...

Recruiting

Comparative Study of Patterns of Immune Response to COVID 19 Vaccination

Immune Response to Covid 19 Vaccination

Egypt
University of Crete

Recruiting

Role of Epithelial Barrier Integrity in Biologic Treatment Response of Severe Asthmatics With/Out Chronic Rhinosinusitis With Nasal Polyps (CRSwNP).

Severe Eosinophilic Asthma w/wo CRSwNP

Greece
Rachael Cusack
Grifols Biologicals, LLC

Recruiting

Microcirculation Properties of Albumin for Fluid Resuscitation in Septic Shock

Sepsis | Septic Shock | Sepsis, Severe

Ireland
University Hospital, Montpellier

Not yet recruiting

Biological Variables Associated With the Response to Intensive Training in Athletes (CareStress)

Muscle Injury

France
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Association Between Gut Microbiome and Dietary Determinants and Vaccine Response

Influenza

United States
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

Evaluation of Immunologic Response Following COVID-19 Vaccination in Children, Adolescents, and Young Adults With Cancer

Malignant Solid Neoplasm | COVID-19 Infection | Hematopoietic and Lymphatic System Neoplasm

United States
Asan Medical Center

Recruiting

Prediction Model for Response to Biologics and Small Molecular Agent for UC

Ulcerative Colitis

Korea, Republic of
University of California, San Francisco
Merck Sharp & Dohme LLC

Recruiting

Peripheral T Cell Determinants of Response and Resistance to Pembrolizumab in Melanoma

Melanoma | Advanced Melanoma

United States
The Second Affiliated Hospital of Chongqing Medical...

Recruiting

Safety and Immune Response of COVID-19 Vaccination in Patients With HIV Infection

HIV Infections | Covid19

China
Mindera Health

Not yet recruiting

A 16-week Randomized Evaluation of the Impact of Mind.Px Application on Response to Biologic Treatment in Patients Suffering From Plaque Psoriasis Through Clinical Utility and Health Outcomes. (MATCH)

Plaque Psoriasis
M.D. Anderson Cancer Center

Recruiting

Anti-Leukemia Immune Responses After Irradiation of Extramedullary Tumors

Acute Myeloid Leukemia | Myeloid Leukemia | Recurrent Acute Myeloid Leukemia

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

TuBerculosis Viability Interregional Study and Agreement on Biological Tests (TBVISA)

Tuberculosis, Pulmonary
Ohio State University Comprehensive Cancer Center

Recruiting

Evaluating Modifiable Biomarkers for the Prediction of Immunotherapy Response and Toxicity

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Lung Non-Squamous Non-Small Cell Carcinoma | Stage IIIB Lung Cancer AJCC v8

United States
National Institute of Environmental Health Sciences...

Recruiting

Natural History of the Human Biological Response to Environmental Exposure and Injury

Inflammation | Metabolic Disease | Normal Controls

United States
Centre Hospitalier Universitaire de Besancon

Recruiting

COVID-19-Study of Immune Responses Following Vaccination Against SARS-CoV-2 (CACOV-VAC)

Cancer | Healthy Aging | Elderly

France
National Jewish Health

Recruiting

Measuring Omalizumab Responses Using Real-world Evidence (MORRE) Study (MORRE)

Asthma

United States

Search clinical trials for: Biologic response

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